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| | SUB1 | SUB1 regulator of transcription. (127 aa) |
| | GDF2 | Growth differentiation factor 2. (429 aa) |
| | GDF10 | Growth differentiation factor 10. (483 aa) |
| | LRRC32 | Leucine rich repeat containing 32. (639 aa) |
| | GDF6 | Growth differentiation factor 6. (289 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (544 aa) |
| | ITGB5 | Integrin beta; Belongs to the integrin beta chain family. (621 aa) |
| | ZFYVE9 | Zinc finger FYVE domain-containing protein. (1422 aa) |
| | MSX1 | Msh homeobox 1. (303 aa) |
| | ENSUAMP00000000756 | MH1 domain-containing protein. (170 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa) |
| | HIPK2 | Homeodomain interacting protein kinase 2. (1200 aa) |
| | ITGB8 | Integrin beta; Belongs to the integrin beta chain family. (767 aa) |
| | ENSUAMP00000001661 | TGF_BETA_2 domain-containing protein. (194 aa) |
| | NOG | Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa) |
| | EID2 | EP300 interacting inhibitor of differentiation 2. (172 aa) |
| | AKAP3 | A-kinase anchoring protein 3. (510 aa) |
| | SPART | Spartin. (672 aa) |
| | DSG4 | Desmoglein 4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1039 aa) |
| | ENSUAMP00000003258 | Uncharacterized protein. (246 aa) |
| | ENSUAMP00000003640 | Uncharacterized protein. (101 aa) |
| | ACVR1 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa) |
| | ENSUAMP00000004097 | Uncharacterized protein. (245 aa) |
| | SFRP1 | Secreted frizzled related protein 1. (337 aa) |
| | TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (504 aa) |
| | FGF9 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | ENSUAMP00000005012 | Uncharacterized protein. (59 aa) |
| | CHRD | Chordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes. (949 aa) |
| | TWSG1 | Twisted gastrulation BMP signaling modulator 1. (202 aa) |
| | MTMR4 | Myotubularin related protein 4. (1195 aa) |
| | ENSUAMP00000006566 | UDENN FLCN/SMCR8-type domain-containing protein. (579 aa) |
| | HES1 | Hes family bHLH transcription factor 1. (259 aa) |
| | ENSUAMP00000006610 | CUT domain-containing protein. (259 aa) |
| | ACVR2B | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (527 aa) |
| | INHBA | Inhibin subunit beta A. (424 aa) |
| | COL3A1 | Collagen type III alpha 1 chain. (997 aa) |
| | FOXH1 | Forkhead box H1. (370 aa) |
| | RNF111 | Ring finger protein 111. (985 aa) |
| | CDH5 | Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (783 aa) |
| | ENSUAMP00000008401 | TGF_BETA_2 domain-containing protein. (367 aa) |
| | STAT3 | Signal transducer and activator of transcription. (770 aa) |
| | JUN | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa) |
| | GDF5 | Growth differentiation factor 5. (499 aa) |
| | ABL1 | Tyrosine-protein kinase. (1138 aa) |
| | NODAL | Nodal growth differentiation factor. (348 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) |
| | ENSUAMP00000010127 | Kindlin_2_N domain-containing protein. (70 aa) |
| | CLDN5 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa) |
| | TGFBR3 | Transforming growth factor beta receptor 3. (808 aa) |
| | ENSUAMP00000010701 | Uncharacterized protein. (51 aa) |
| | ENSUAMP00000011475 | PPM-type phosphatase domain-containing protein. (216 aa) |
| | WFIKKN2 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2. (573 aa) |
| | ENSUAMP00000012044 | TGF_BETA_2 domain-containing protein. (154 aa) |
| | ENSUAMP00000012266 | CTNNB1_binding domain-containing protein. (162 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | EXT1 | Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (506 aa) |
| | MEGF8 | Multiple EGF like domains 8. (2820 aa) |
| | ENSUAMP00000014216 | Homeobox domain-containing protein. (315 aa) |
| | CHRDL1 | Chordin like 1. (414 aa) |
| | GDF3 | Growth differentiation factor 3. (365 aa) |
| | LTBP4 | Latent transforming growth factor beta binding protein 4. (1577 aa) |
| | FAM83G | Family with sequence similarity 83 member G. (822 aa) |
| | ACVR2A | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (510 aa) |
| | ATOH8 | Atonal bHLH transcription factor 8. (322 aa) |
| | ENSUAMP00000015227 | Uncharacterized protein. (167 aa) |
| | BMP10 | Bone morphogenetic protein 10. (424 aa) |
| | USP15 | Ubiquitin specific peptidase 15; Belongs to the peptidase C19 family. (968 aa) |
| | TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa) |
| | ENSUAMP00000016793 | BZIP domain-containing protein. (179 aa) |
| | ENSUAMP00000016813 | Uncharacterized protein. (404 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (501 aa) |
| | SOSTDC1 | Sclerostin domain containing 1. (206 aa) |
| | SMURF2 | E3 ubiquitin-protein ligase. (736 aa) |
| | ACVRL1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (518 aa) |
| | ACVR1B | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (505 aa) |
| | ENSUAMP00000017561 | Uncharacterized protein. (285 aa) |
| | TGFB1I1 | Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (464 aa) |
| | TDGF1 | Teratocarcinoma-derived growth factor 1. (184 aa) |
| | FERMT2 | Fermitin family member 2. (567 aa) |
| | DLX3 | Distal-less homeobox 3. (287 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog. (552 aa) |
| | GDF11 | Growth differentiation factor 11. (409 aa) |
| | RBM14 | RNA binding motif protein 14. (618 aa) |
| | SKIL | SKI like proto-oncogene. (684 aa) |
| | NRROS | Negative regulator of reactive oxygen species. (692 aa) |
| | SLC33A1 | Solute carrier family 33 member 1. (550 aa) |
| | SMPD3 | Sphingomyelin phosphodiesterase 3. (658 aa) |
| | AFP | Alpha fetoprotein. (614 aa) |
| | PTPRK | Uncharacterized protein. (786 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (439 aa) |
| | HFE | Homeostatic iron regulator; Belongs to the MHC class I family. (355 aa) |
| | ENSUAMP00000020920 | Uncharacterized protein. (86 aa) |
| | SIRT1 | Sirtuin 1. (618 aa) |
| | BMP2 | Bone morphogenetic protein 2. (395 aa) |
| | NUP93 | Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (819 aa) |
| | HNF4A | Hepatocyte nuclear factor 4 alpha. (474 aa) |
| | NCEH1 | Neutral cholesterol ester hydrolase 1. (402 aa) |
| | BMP6 | Bone morphogenetic protein 6. (384 aa) |
| | SMAD5 | Mothers against decapentaplegic homolog. (465 aa) |
| | ENSUAMP00000022378 | TGF_BETA_2 domain-containing protein. (155 aa) |
| | ENSUAMP00000022406 | Uncharacterized protein. (242 aa) |
| | ACVR1C | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (494 aa) |
| | CITED2 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa) |
| | ENSUAMP00000023083 | Uncharacterized protein. (485 aa) |
| | SOST | Sclerostin. (213 aa) |
| | CITED1 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (195 aa) |
| | NLK | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa) |
| | SKI | SKI proto-oncogene. (704 aa) |
| | ENSUAMP00000024123 | Uncharacterized protein. (522 aa) |
| | INHBC | Inhibin subunit beta C. (352 aa) |
| | INHBE | Inhibin subunit beta E. (351 aa) |
| | TMPRSS6 | Transmembrane serine protease 6; Belongs to the peptidase S1 family. (800 aa) |
| | ZNF8 | Zinc finger protein 8. (566 aa) |
| | GLG1 | Golgi glycoprotein 1. (1111 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | SMAD6 | Mothers against decapentaplegic homolog. (484 aa) |
| | SMAD2 | Mothers against decapentaplegic homolog. (467 aa) |
| | ENSUAMP00000026772 | ETS domain-containing protein. (163 aa) |
| | ENSUAMP00000026773 | Uncharacterized protein. (179 aa) |
| | COL1A2 | Collagen type I alpha 2 chain. (1243 aa) |
| | LTBP3 | Latent transforming growth factor beta binding protein 3. (1169 aa) |
| | SMAD7 | Mothers against decapentaplegic homolog. (426 aa) |
| | TGFBR3L | Transforming growth factor beta receptor 3 like. (290 aa) |
| | CCDC142 | Coiled-coil domain containing 142. (747 aa) |
| | HPGD | 15-hydroxyprostaglandin dehydrogenase. (172 aa) |
| | RGMA | Repulsive guidance molecule BMP co-receptor a. (439 aa) |
| | ZYX | Zyxin. (576 aa) |
| | HJV | Hemojuvelin BMP co-receptor. (317 aa) |
| | ZNF831 | Zinc finger protein 831. (1654 aa) |
| | BMP4 | Bone morphogenetic protein 4. (409 aa) |
| | HNF1A | HNF1 homeobox A. (631 aa) |
| | USP9X | Ubiquitin specific peptidase 9 X-linked; Belongs to the peptidase C19 family. (2153 aa) |
| | DLX5 | Distal-less homeobox 5. (289 aa) |
| | AKAP4 | A-kinase anchoring protein 4. (856 aa) |
| | FST | Follistatin. (344 aa) |
| | ENG | Endoglin. (650 aa) |
| | ADAM9 | ADAM metallopeptidase domain 9. (572 aa) |
| | SRC | Tyrosine-protein kinase. (557 aa) |
| | DDX5 | DEAD-box helicase 5; Belongs to the DEAD box helicase family. (614 aa) |
| | INHA | Inhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (368 aa) |
| | MSTN | Myostatin. (376 aa) |
| | ENSUAMP00000031224 | Uncharacterized protein. (323 aa) |
| | MAPK3 | Mitogen-activated protein kinase. (354 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (567 aa) |
| | TMEM100 | Transmembrane protein 100. (134 aa) |
| | SMAD9 | Mothers against decapentaplegic homolog. (469 aa) |
| | NPNT | Nephronectin. (462 aa) |
| | PDCD4 | Programmed cell death 4. (474 aa) |
| | BMPR1B | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (502 aa) |
| | LPXN | Leupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (379 aa) |
| | PML | Promyelocytic leukemia. (877 aa) |
| | BMP3 | Bone morphogenetic protein 3; Belongs to the TGF-beta family. (475 aa) |
| | ENSUAMP00000033758 | Uncharacterized protein. (409 aa) |
| | ENSUAMP00000033771 | Beta-hexosaminidase. (529 aa) |
| | NOTCH2 | Notch receptor 2. (2374 aa) |
| | ENSUAMP00000033951 | Uncharacterized protein. (383 aa) |
| | ENSUAMP00000034195 | Uncharacterized protein. (1577 aa) |
| | APPL2 | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (652 aa) |
| | PXN | Uncharacterized protein. (1082 aa) |
| | WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa) |
| | ENSUAMP00000035777 | HMG box domain-containing protein. (191 aa) |
| | RGMB | Repulsive guidance molecule BMP co-receptor b. (441 aa) |
| | SLC39A5 | Solute carrier family 39 member 5. (472 aa) |
| | APPL1 | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (665 aa) |
| | VIM | Vimentin; Belongs to the intermediate filament family. (447 aa) |
| | BMPR1A | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa) |
| | COMP | Cartilage oligomeric matrix protein. (756 aa) |
| | BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (857 aa) |
| | ENSUAMP00000037566 | TGF_BETA_2 domain-containing protein. (293 aa) |
| | ZMIZ1 | Zinc finger MIZ-type containing 1. (1044 aa) |
