STRINGSTRING
PCGF5 PCGF5 ENSUAMP00000003678 ENSUAMP00000003678 DDB2 DDB2 CUL4B CUL4B ENSUAMP00000009022 ENSUAMP00000009022 ENSUAMP00000009030 ENSUAMP00000009030 ENSUAMP00000009854 ENSUAMP00000009854 RYBP RYBP CDC73 CDC73 PAF1 PAF1 UHRF1 UHRF1 KDM2B KDM2B LEO1 LEO1 PCGF3 PCGF3 WAC WAC DDB1 DDB1 RNF20 RNF20 RNF2 RNF2 CTR9 CTR9 RAG1 RAG1 PCGF1 PCGF1 ENSUAMP00000028265 ENSUAMP00000028265 ENSUAMP00000028840 ENSUAMP00000028840 DTX3L DTX3L ATXN7L3 ATXN7L3 RNF40 RNF40 RING1 RING1 PCGF6 PCGF6 PCGF2 PCGF2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PCGF5Polycomb group ring finger 5. (190 aa)
ENSUAMP00000003678Uncharacterized protein. (542 aa)
DDB2Damage specific DNA binding protein 2. (421 aa)
CUL4BCullin 4B; Belongs to the cullin family. (879 aa)
ENSUAMP00000009022RING-type domain-containing protein. (140 aa)
ENSUAMP00000009030Uncharacterized protein. (304 aa)
ENSUAMP00000009854Uncharacterized protein. (319 aa)
RYBPRING1 and YY1 binding protein. (214 aa)
CDC73Cell division cycle 73. (519 aa)
PAF1PAF1 homolog, Paf1/RNA polymerase II complex component. (528 aa)
UHRF1Ubiquitin like with PHD and ring finger domains 1. (812 aa)
KDM2BLysine demethylase 2B. (1282 aa)
LEO1LEO1 homolog, Paf1/RNA polymerase II complex component. (618 aa)
PCGF3Polycomb group ring finger 3. (267 aa)
WACWW domain containing adaptor with coiled-coil. (617 aa)
DDB1Damage specific DNA binding protein 1. (1151 aa)
RNF20E3 ubiquitin protein ligase; Belongs to the BRE1 family. (975 aa)
RNF2Ring finger protein 2. (336 aa)
CTR9CTR9 homolog, Paf1/RNA polymerase II complex component. (1173 aa)
RAG1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1043 aa)
PCGF1Polycomb group ring finger 1. (263 aa)
ENSUAMP00000028265RING-type domain-containing protein. (357 aa)
ENSUAMP00000028840RING-type domain-containing protein. (116 aa)
DTX3LDeltex E3 ubiquitin ligase 3L. (688 aa)
ATXN7L3Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] (408 aa)
RNF40E3 ubiquitin protein ligase; Belongs to the BRE1 family. (1001 aa)
RING1Ring finger protein 1. (406 aa)
PCGF6Polycomb group ring finger 6. (322 aa)
PCGF2Polycomb group ring finger 2. (344 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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