(12 nodes) Coenzyme A biosynthetic process network (Ursus americanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSUAMP00000002512	Uncharacterized protein. (197 aa)
	ACOT7	Acyl-CoA thioesterase 7. (357 aa)
	COASY	Coenzyme A synthase. (560 aa)
	ACAT1	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (417 aa)
	ENSUAMP00000010000	Uncharacterized protein. (245 aa)
	ENSUAMP00000010002	Uncharacterized protein. (220 aa)
	PPCS	Phosphopantothenoylcysteine synthetase. (310 aa)
	PPCDC	Phosphopantothenoylcysteine decarboxylase. (204 aa)
	PANK3	Pantothenate kinase 3. (368 aa)
	PANK4	4'-phosphopantetheine phosphatase; May play a role in the physiological regulation of coenzyme A (CoA) intracellular levels. The phosphatase activity shows preference for normal or oxidatively damaged intermediates of 4'- phosphopantetheine, which provides strong indirect evidence that the phosphatase activity pre-empts damage in the CoA pathway. (789 aa)
	PANK2	Pantothenate kinase 2. (451 aa)
	DCAKD	Dephospho-CoA kinase domain containing. (231 aa)

Your Current Organism:

Ursus americanus

NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COASY	DCAKD	ENSUAMP00000008730	ENSUAMP00000023093	Coenzyme A synthase.	Dephospho-CoA kinase domain containing.	0.814
COASY	ENSUAMP00000002512	ENSUAMP00000008730	ENSUAMP00000002512	Coenzyme A synthase.	Uncharacterized protein.	0.968
COASY	ENSUAMP00000010000	ENSUAMP00000008730	ENSUAMP00000010000	Coenzyme A synthase.	Uncharacterized protein.	0.914
COASY	ENSUAMP00000010002	ENSUAMP00000008730	ENSUAMP00000010002	Coenzyme A synthase.	Uncharacterized protein.	0.914
COASY	PANK2	ENSUAMP00000008730	ENSUAMP00000035481	Coenzyme A synthase.	Pantothenate kinase 2.	0.978
COASY	PANK3	ENSUAMP00000008730	ENSUAMP00000030355	Coenzyme A synthase.	Pantothenate kinase 3.	0.968
COASY	PANK4	ENSUAMP00000008730	ENSUAMP00000034355	Coenzyme A synthase.	4'-phosphopantetheine phosphatase; May play a role in the physiological regulation of coenzyme A (CoA) intracellular levels. The phosphatase activity shows preference for normal or oxidatively damaged intermediates of 4'- phosphopantetheine, which provides strong indirect evidence that the phosphatase activity pre-empts damage in the CoA pathway.	0.979
COASY	PPCDC	ENSUAMP00000008730	ENSUAMP00000024115	Coenzyme A synthase.	Phosphopantothenoylcysteine decarboxylase.	0.977
COASY	PPCS	ENSUAMP00000008730	ENSUAMP00000010005	Coenzyme A synthase.	Phosphopantothenoylcysteine synthetase.	0.915
DCAKD	COASY	ENSUAMP00000023093	ENSUAMP00000008730	Dephospho-CoA kinase domain containing.	Coenzyme A synthase.	0.814
DCAKD	ENSUAMP00000002512	ENSUAMP00000023093	ENSUAMP00000002512	Dephospho-CoA kinase domain containing.	Uncharacterized protein.	0.440
DCAKD	ENSUAMP00000010000	ENSUAMP00000023093	ENSUAMP00000010000	Dephospho-CoA kinase domain containing.	Uncharacterized protein.	0.495
DCAKD	ENSUAMP00000010002	ENSUAMP00000023093	ENSUAMP00000010002	Dephospho-CoA kinase domain containing.	Uncharacterized protein.	0.495
DCAKD	PANK2	ENSUAMP00000023093	ENSUAMP00000035481	Dephospho-CoA kinase domain containing.	Pantothenate kinase 2.	0.440
DCAKD	PANK3	ENSUAMP00000023093	ENSUAMP00000030355	Dephospho-CoA kinase domain containing.	Pantothenate kinase 3.	0.574
DCAKD	PANK4	ENSUAMP00000023093	ENSUAMP00000034355	Dephospho-CoA kinase domain containing.	4'-phosphopantetheine phosphatase; May play a role in the physiological regulation of coenzyme A (CoA) intracellular levels. The phosphatase activity shows preference for normal or oxidatively damaged intermediates of 4'- phosphopantetheine, which provides strong indirect evidence that the phosphatase activity pre-empts damage in the CoA pathway.	0.914
DCAKD	PPCDC	ENSUAMP00000023093	ENSUAMP00000024115	Dephospho-CoA kinase domain containing.	Phosphopantothenoylcysteine decarboxylase.	0.808
DCAKD	PPCS	ENSUAMP00000023093	ENSUAMP00000010005	Dephospho-CoA kinase domain containing.	Phosphopantothenoylcysteine synthetase.	0.747
ENSUAMP00000002512	COASY	ENSUAMP00000002512	ENSUAMP00000008730	Uncharacterized protein.	Coenzyme A synthase.	0.968
ENSUAMP00000002512	DCAKD	ENSUAMP00000002512	ENSUAMP00000023093	Uncharacterized protein.	Dephospho-CoA kinase domain containing.	0.440