(31 nodes) Proton motive force-driven ATP synthesis network (Ursus americanus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

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protein homology

Your Input:
	ENSUAMP00000028470	Uncharacterized protein. (178 aa)
	ENSUAMP00000022055	Uncharacterized protein. (88 aa)
	ATP5MD	ATP synthase membrane subunit DAPIT. (58 aa)
	ENSUAMP00000020606	Uncharacterized protein. (81 aa)
	ATP5F1B	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (528 aa)
	ATP5F1A	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (578 aa)
	ENSUAMP00000023736	Uncharacterized protein. (60 aa)
	ENSUAMP00000025606	ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (163 aa)
	ENSUAMP00000003773	ATP synthase subunit; Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proto [...] (103 aa)
	ENSUAMP00000004574	Uncharacterized protein. (86 aa)
	ATP5PF	ATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain; Belongs to the eukaryotic ATPase subunit F6 family. (108 aa)
	ENSUAMP00000007626	ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (155 aa)
	C17orf80	Chromosome 17 open reading frame 80. (592 aa)
	ENSUAMP00000001637	Uncharacterized protein. (76 aa)
	ATP5MC3	ATP synthase membrane subunit c locus 3; Belongs to the ATPase C chain family. (199 aa)
	ATP5MC2	ATP synthase membrane subunit c locus 2; Belongs to the ATPase C chain family. (145 aa)
	ENSUAMP00000012985	ATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (161 aa)
	ENSUAMP00000015733	Uncharacterized protein. (73 aa)
	ENSUAMP00000017439	ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (136 aa)
	ENSUAMP00000037342	Uncharacterized protein. (213 aa)
	ATP5F1C	ATP synthase subunit gamma. (298 aa)
	ATP6V1A	ATPase H+ transporting V1 subunit A. (618 aa)
	ENSUAMP00000034617	Uncharacterized protein. (85 aa)
	ENSUAMP00000000532	Uncharacterized protein. (106 aa)
	ATP5PB	ATP synthase peripheral stalk-membrane subunit b. (256 aa)
	ATP5F1D	ATP synthase F1 subunit delta. (219 aa)
	ENSUAMP00000026220	Uncharacterized protein. (100 aa)
	ENSUAMP00000026219	Uncharacterized protein. (132 aa)
	ENSUAMP00000033499	Uncharacterized protein. (66 aa)
	STOML2	Stomatin like 2. (356 aa)
	ENSUAMP00000030335	ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (136 aa)

Your Current Organism:

Ursus americanus

NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP5F1A	ATP5F1B	ENSUAMP00000023236	ENSUAMP00000028116	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.999
ATP5F1A	ATP5F1C	ENSUAMP00000023236	ENSUAMP00000017457	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	ATP synthase subunit gamma.	0.999
ATP5F1A	ATP5F1D	ENSUAMP00000023236	ENSUAMP00000018477	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	ATP synthase F1 subunit delta.	0.999
ATP5F1A	ATP5MC2	ENSUAMP00000023236	ENSUAMP00000010955	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	ATP synthase membrane subunit c locus 2; Belongs to the ATPase C chain family.	0.997
ATP5F1A	ATP5MC3	ENSUAMP00000023236	ENSUAMP00000010045	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	ATP synthase membrane subunit c locus 3; Belongs to the ATPase C chain family.	0.999
ATP5F1A	ATP5MD	ENSUAMP00000023236	ENSUAMP00000022971	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	ATP synthase membrane subunit DAPIT.	0.997
ATP5F1A	ATP5PB	ENSUAMP00000023236	ENSUAMP00000018387	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	ATP synthase peripheral stalk-membrane subunit b.	0.999
ATP5F1A	ATP5PF	ENSUAMP00000023236	ENSUAMP00000006983	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	ATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain; Belongs to the eukaryotic ATPase subunit F6 family.	0.999
ATP5F1A	ATP6V1A	ENSUAMP00000023236	ENSUAMP00000034806	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	ATPase H+ transporting V1 subunit A.	0.864
ATP5F1A	C17orf80	ENSUAMP00000023236	ENSUAMP00000009265	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Chromosome 17 open reading frame 80.	0.923
ATP5F1A	ENSUAMP00000000532	ENSUAMP00000023236	ENSUAMP00000000532	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Uncharacterized protein.	0.997
ATP5F1A	ENSUAMP00000001637	ENSUAMP00000023236	ENSUAMP00000001637	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Uncharacterized protein.	0.988
ATP5F1A	ENSUAMP00000003773	ENSUAMP00000023236	ENSUAMP00000003773	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	ATP synthase subunit; Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proto [...]	0.998
ATP5F1A	ENSUAMP00000004574	ENSUAMP00000023236	ENSUAMP00000004574	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Uncharacterized protein.	0.997
ATP5F1A	ENSUAMP00000007626	ENSUAMP00000023236	ENSUAMP00000007626	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family.	0.996
ATP5F1A	ENSUAMP00000012985	ENSUAMP00000023236	ENSUAMP00000012985	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	ATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...]	0.999
ATP5F1A	ENSUAMP00000015733	ENSUAMP00000023236	ENSUAMP00000015733	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Uncharacterized protein.	0.997
ATP5F1A	ENSUAMP00000017439	ENSUAMP00000023236	ENSUAMP00000017439	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family.	0.996
ATP5F1A	ENSUAMP00000020606	ENSUAMP00000023236	ENSUAMP00000020606	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Uncharacterized protein.	0.999
ATP5F1A	ENSUAMP00000022055	ENSUAMP00000023236	ENSUAMP00000022055	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Uncharacterized protein.	0.988