STRINGSTRING
ADIPOR2 ADIPOR2 MCHR1 MCHR1 RXFP2 RXFP2 LGR5 LGR5 IGF1R IGF1R LGR4 LGR4 INSRR INSRR INSR INSR ADIPOR1 ADIPOR1 ENSUAMP00000024427 ENSUAMP00000024427 DCAF8 DCAF8 FSHR FSHR LGR6 LGR6 ENSUAMP00000028222 ENSUAMP00000028222 ENSUAMP00000028357 ENSUAMP00000028357 LHCGR LHCGR TSHR TSHR CMKLR1 CMKLR1 GPR1 GPR1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADIPOR2Adiponectin receptor 2. (386 aa)
MCHR1Melanin concentrating hormone receptor 1. (392 aa)
RXFP2Relaxin family peptide receptor 2. (720 aa)
LGR5Leucine rich repeat containing G protein-coupled receptor 5. (907 aa)
IGF1RTyrosine-protein kinase receptor. (1288 aa)
LGR4Leucine rich repeat containing G protein-coupled receptor 4. (971 aa)
INSRRTyrosine-protein kinase receptor. (1318 aa)
INSRTyrosine-protein kinase receptor. (1072 aa)
ADIPOR1Adiponectin receptor 1. (375 aa)
ENSUAMP00000024427Recep_L_domain domain-containing protein. (297 aa)
DCAF8DDB1 and CUL4 associated factor 8. (596 aa)
FSHRFollicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (691 aa)
LGR6Leucine rich repeat containing G protein-coupled receptor 6. (910 aa)
ENSUAMP00000028222WD_REPEATS_REGION domain-containing protein. (595 aa)
ENSUAMP00000028357G_PROTEIN_RECEP_F1_2 domain-containing protein. (377 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (673 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa)
CMKLR1Chemerin chemokine-like receptor 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
GPR1G protein-coupled receptor 1; Belongs to the G-protein coupled receptor 1 family. (387 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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