(15 nodes) NuRD complex network (Ursus americanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSUAMP00000002604	CAF1C_H4-bd domain-containing protein. (133 aa)
	CHD3	Chromodomain helicase DNA binding protein 3. (1838 aa)
	CHD5	Chromodomain helicase DNA binding protein 5. (1942 aa)
	ENSUAMP00000029725	Uncharacterized protein. (1947 aa)
	ZBTB7A	Zinc finger and BTB domain containing 7A. (529 aa)
	MTA3	Metastasis associated 1 family member 3. (589 aa)
	MBD3	Methyl-CpG binding domain protein 3. (295 aa)
	HDAC1	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (479 aa)
	ENSUAMP00000017773	CAF1C_H4-bd domain-containing protein. (87 aa)
	MTA1	Metastasis associated 1. (741 aa)
	RBBP7	RB binding protein 7, chromatin remodeling factor. (427 aa)
	GATAD2B	GATA zinc finger domain containing 2B. (593 aa)
	MTA2	Metastasis associated 1 family member 2. (668 aa)
	GATAD2A	GATA zinc finger domain containing 2A. (639 aa)
	HDAC2	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (446 aa)

Your Current Organism:

Ursus americanus

NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHD3	ENSUAMP00000002604	ENSUAMP00000006397	ENSUAMP00000002604	Chromodomain helicase DNA binding protein 3.	CAF1C_H4-bd domain-containing protein.	0.860
CHD3	ENSUAMP00000017773	ENSUAMP00000006397	ENSUAMP00000017773	Chromodomain helicase DNA binding protein 3.	CAF1C_H4-bd domain-containing protein.	0.860
CHD3	ENSUAMP00000029725	ENSUAMP00000006397	ENSUAMP00000029725	Chromodomain helicase DNA binding protein 3.	Uncharacterized protein.	0.918
CHD3	GATAD2A	ENSUAMP00000006397	ENSUAMP00000000667	Chromodomain helicase DNA binding protein 3.	GATA zinc finger domain containing 2A.	0.979
CHD3	GATAD2B	ENSUAMP00000006397	ENSUAMP00000007652	Chromodomain helicase DNA binding protein 3.	GATA zinc finger domain containing 2B.	0.956
CHD3	HDAC1	ENSUAMP00000006397	ENSUAMP00000017970	Chromodomain helicase DNA binding protein 3.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.909
CHD3	HDAC2	ENSUAMP00000006397	ENSUAMP00000001578	Chromodomain helicase DNA binding protein 3.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.909
CHD3	MBD3	ENSUAMP00000006397	ENSUAMP00000018561	Chromodomain helicase DNA binding protein 3.	Methyl-CpG binding domain protein 3.	0.897
CHD3	MTA1	ENSUAMP00000006397	ENSUAMP00000012686	Chromodomain helicase DNA binding protein 3.	Metastasis associated 1.	0.922
CHD3	MTA2	ENSUAMP00000006397	ENSUAMP00000035906	Chromodomain helicase DNA binding protein 3.	Metastasis associated 1 family member 2.	0.945
CHD3	MTA3	ENSUAMP00000006397	ENSUAMP00000022386	Chromodomain helicase DNA binding protein 3.	Metastasis associated 1 family member 3.	0.915
CHD3	RBBP7	ENSUAMP00000006397	ENSUAMP00000009562	Chromodomain helicase DNA binding protein 3.	RB binding protein 7, chromatin remodeling factor.	0.939
CHD3	ZBTB7A	ENSUAMP00000006397	ENSUAMP00000029033	Chromodomain helicase DNA binding protein 3.	Zinc finger and BTB domain containing 7A.	0.496
CHD5	ENSUAMP00000002604	ENSUAMP00000032051	ENSUAMP00000002604	Chromodomain helicase DNA binding protein 5.	CAF1C_H4-bd domain-containing protein.	0.732
CHD5	ENSUAMP00000017773	ENSUAMP00000032051	ENSUAMP00000017773	Chromodomain helicase DNA binding protein 5.	CAF1C_H4-bd domain-containing protein.	0.732
CHD5	GATAD2A	ENSUAMP00000032051	ENSUAMP00000000667	Chromodomain helicase DNA binding protein 5.	GATA zinc finger domain containing 2A.	0.795
CHD5	GATAD2B	ENSUAMP00000032051	ENSUAMP00000007652	Chromodomain helicase DNA binding protein 5.	GATA zinc finger domain containing 2B.	0.839
CHD5	HDAC1	ENSUAMP00000032051	ENSUAMP00000017970	Chromodomain helicase DNA binding protein 5.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.656
CHD5	HDAC2	ENSUAMP00000032051	ENSUAMP00000001578	Chromodomain helicase DNA binding protein 5.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.656
CHD5	MBD3	ENSUAMP00000032051	ENSUAMP00000018561	Chromodomain helicase DNA binding protein 5.	Methyl-CpG binding domain protein 3.	0.740