STRINGSTRING
DHRS11 DHRS11 PTGR1 PTGR1 ENSUAMP00000030699 ENSUAMP00000030699 HSD17B10 HSD17B10 DHRS7C DHRS7C ENSUAMP00000031210 ENSUAMP00000031210 H6PD H6PD ENSUAMP00000031664 ENSUAMP00000031664 ENSUAMP00000031737 ENSUAMP00000031737 ENSUAMP00000031741 ENSUAMP00000031741 DHRS1 DHRS1 RDH14 RDH14 KCNAB2 KCNAB2 ENSUAMP00000032060 ENSUAMP00000032060 SORD SORD FASN FASN ENSUAMP00000032699 ENSUAMP00000032699 PHGDH PHGDH SDR42E1 SDR42E1 HSD17B2 HSD17B2 SDR16C5 SDR16C5 HSD17B13 HSD17B13 HSD17B11 HSD17B11 ENSUAMP00000033916 ENSUAMP00000033916 ENSUAMP00000034153 ENSUAMP00000034153 PRXL2B PRXL2B HSD17B8 HSD17B8 HADH HADH ENSUAMP00000037252 ENSUAMP00000037252 PGD PGD UGDH UGDH HSD17B12 HSD17B12 ENSUAMP00000000227 ENSUAMP00000000227 ENSUAMP00000000505 ENSUAMP00000000505 ENSUAMP00000001439 ENSUAMP00000001439 ENSUAMP00000001533 ENSUAMP00000001533 BDH2 BDH2 ENSUAMP00000003052 ENSUAMP00000003052 ENSUAMP00000003092 ENSUAMP00000003092 ADH6 ADH6 ENSUAMP00000003267 ENSUAMP00000003267 ENSUAMP00000003631 ENSUAMP00000003631 ENSUAMP00000003802 ENSUAMP00000003802 ENSUAMP00000003971 ENSUAMP00000003971 ENSUAMP00000004224 ENSUAMP00000004224 ENSUAMP00000004597 ENSUAMP00000004597 AKR1B1 AKR1B1 ENSUAMP00000005190 ENSUAMP00000005190 ENSUAMP00000005609 ENSUAMP00000005609 ENSUAMP00000005719 ENSUAMP00000005719 KCNAB3 KCNAB3 ENSUAMP00000006381 ENSUAMP00000006381 IDH3B IDH3B ENSUAMP00000007016 ENSUAMP00000007016 ENSUAMP00000007027 ENSUAMP00000007027 ENSUAMP00000008515 ENSUAMP00000008515 AKR1E2 AKR1E2 AKR1C8P AKR1C8P IMPDH1 IMPDH1 HSD17B1 HSD17B1 DHRS2 DHRS2 RDH10 RDH10 IDH2 IDH2 RNF138 RNF138 AKR1A1 AKR1A1 ENSUAMP00000010334 ENSUAMP00000010334 HADHA HADHA DHRS7 DHRS7 ENSUAMP00000011425 ENSUAMP00000011425 IDH1 IDH1 ENSUAMP00000011619 ENSUAMP00000011619 ENSUAMP00000011699 ENSUAMP00000011699 KDSR KDSR RDH12 RDH12 ENSUAMP00000012555 ENSUAMP00000012555 HMGCR HMGCR HSD17B14 HSD17B14 DHDH DHDH ENSUAMP00000013499 ENSUAMP00000013499 SDR9C7 SDR9C7 RDH16 RDH16 MDH2 MDH2 G6PD G6PD SRD5A2 SRD5A2 ADH4 ADH4 ENSUAMP00000014798 ENSUAMP00000014798 ENSUAMP00000014859 ENSUAMP00000014859 BDH1 BDH1 GRHPR GRHPR ENSUAMP00000016165 ENSUAMP00000016165 ME1 ME1 MDH1 MDH1 GPD1 GPD1 ENSUAMP00000017482 ENSUAMP00000017482 HSD3B7 HSD3B7 RDH5 RDH5 URB2 URB2 ENSUAMP00000019553 ENSUAMP00000019553 ENSUAMP00000019554 ENSUAMP00000019554 ME2 ME2 AKR1D1 AKR1D1 ENSUAMP00000020051 ENSUAMP00000020051 DHRS13 DHRS13 ENSUAMP00000020160 ENSUAMP00000020160 ENSUAMP00000020162 ENSUAMP00000020162 IDH3G IDH3G NSDHL NSDHL HSD11B1 HSD11B1 ENSUAMP00000021877 ENSUAMP00000021877 SPR SPR LDHD LDHD RDH13 RDH13 IMPDH2 IMPDH2 ENSUAMP00000022722 ENSUAMP00000022722 CBR3 CBR3 IDH3A IDH3A RDH8 RDH8 LDHAL6B LDHAL6B ENSUAMP00000024468 ENSUAMP00000024468 ENSUAMP00000024469 ENSUAMP00000024469 ENSUAMP00000024472 ENSUAMP00000024472 ENSUAMP00000024473 ENSUAMP00000024473 LDHA LDHA ENSUAMP00000024543 ENSUAMP00000024543 ENSUAMP00000024577 ENSUAMP00000024577 ZADH2 ZADH2 DHRS9 DHRS9 DHRS3 DHRS3 CBR4 CBR4 ENSUAMP00000026055 ENSUAMP00000026055 ENSUAMP00000027042 ENSUAMP00000027042 CTBP1 CTBP1 FAM114A2 FAM114A2 ENSUAMP00000027938 ENSUAMP00000027938 ENSUAMP00000028100 ENSUAMP00000028100 HSD17B6 HSD17B6 HPGD HPGD HIBADH HIBADH KCNAB1 KCNAB1 ENSUAMP00000030237 ENSUAMP00000030237
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DHRS11Dehydrogenase/reductase 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (332 aa)
PTGR1Prostaglandin reductase 1. (300 aa)
ENSUAMP00000030699NAD_Gly3P_dh_N domain-containing protein. (180 aa)
HSD17B10Hydroxysteroid 17-beta dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (261 aa)
DHRS7CDehydrogenase/reductase 7C; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (312 aa)
ENSUAMP00000031210Uncharacterized protein. (296 aa)
H6PDHexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase. (804 aa)
ENSUAMP00000031664annotation not available (372 aa)
ENSUAMP00000031737Uncharacterized protein. (187 aa)
ENSUAMP00000031741Uncharacterized protein. (295 aa)
DHRS1Dehydrogenase/reductase 1. (313 aa)
RDH14Retinol dehydrogenase 14; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (336 aa)
KCNAB2Potassium voltage-gated channel subfamily A regulatory beta subunit 2. (382 aa)
ENSUAMP00000032060Uncharacterized protein. (403 aa)
SORDSorbitol dehydrogenase. (319 aa)
FASNFatty acid synthase. (2519 aa)
ENSUAMP000000326993Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. (373 aa)
PHGDHD-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (533 aa)
SDR42E1Short chain dehydrogenase/reductase family 42E, member 1; Belongs to the 3-beta-HSD family. (393 aa)
HSD17B2Hydroxysteroid 17-beta dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (380 aa)
SDR16C5Short chain dehydrogenase/reductase family 16C member 5; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (309 aa)
HSD17B13Hydroxysteroid 17-beta dehydrogenase 13; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (300 aa)
HSD17B11Hydroxysteroid 17-beta dehydrogenase 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (300 aa)
ENSUAMP00000033916Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (328 aa)
ENSUAMP00000034153Epimerase domain-containing protein. (268 aa)
PRXL2BPeroxiredoxin like 2B. (218 aa)
HSD17B8Hydroxysteroid 17-beta dehydrogenase 8. (259 aa)
HADHHydroxyacyl-CoA dehydrogenase. (374 aa)
ENSUAMP00000037252PKS_ER domain-containing protein. (390 aa)
PGD6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (483 aa)
UGDHUDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (494 aa)
HSD17B12Hydroxysteroid 17-beta dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (227 aa)
ENSUAMP00000000227Uncharacterized protein. (123 aa)
ENSUAMP00000000505Uncharacterized protein. (231 aa)
ENSUAMP00000001439Ldh_1_C domain-containing protein. (58 aa)
ENSUAMP00000001533Uncharacterized protein. (98 aa)
BDH23-hydroxybutyrate dehydrogenase 2. (265 aa)
ENSUAMP00000003052Uncharacterized protein. (372 aa)
ENSUAMP00000003092Aldo_ket_red domain-containing protein. (163 aa)
ADH6Alcohol dehydrogenase 6 (class V). (400 aa)
ENSUAMP00000003267Aldo_ket_red domain-containing protein. (354 aa)
ENSUAMP00000003631Uncharacterized protein. (189 aa)
ENSUAMP00000003802Uncharacterized protein. (368 aa)
ENSUAMP00000003971Ldh_1_C domain-containing protein. (101 aa)
ENSUAMP00000004224Uncharacterized protein. (169 aa)
ENSUAMP00000004597Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (292 aa)
AKR1B1Aldo-keto reductase family 1 member B. (285 aa)
ENSUAMP00000005190Ldh_1_N domain-containing protein. (221 aa)
ENSUAMP00000005609Uncharacterized protein. (351 aa)
ENSUAMP00000005719Ldh_1_N domain-containing protein. (127 aa)
KCNAB3Potassium voltage-gated channel subfamily A regulatory beta subunit 3. (428 aa)
ENSUAMP00000006381Uncharacterized protein. (307 aa)
IDH3BIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (385 aa)
ENSUAMP00000007016Uncharacterized protein. (241 aa)
ENSUAMP00000007027Uncharacterized protein. (81 aa)
ENSUAMP00000008515Uncharacterized protein. (148 aa)
AKR1E2Aldo-keto reductase family 1 member E2. (301 aa)
AKR1C8PAldo-keto reductase family 1 member C8, pseudogene. (324 aa)
IMPDH1Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (609 aa)
HSD17B1Hydroxysteroid 17-beta dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (312 aa)
DHRS2Dehydrogenase/reductase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (245 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
IDH2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (421 aa)
RNF138Ring finger protein 138. (245 aa)
AKR1A1Aldo-keto reductase family 1 member A1. (333 aa)
ENSUAMP00000010334Fe-ADH domain-containing protein. (433 aa)
HADHAHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. (812 aa)
DHRS7Dehydrogenase/reductase 7; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (339 aa)
ENSUAMP00000011425Malic domain-containing protein. (254 aa)
IDH1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
ENSUAMP00000011619Malic_M domain-containing protein. (256 aa)
ENSUAMP00000011699NAD_Gly3P_dh_C domain-containing protein. (117 aa)
KDSR3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (317 aa)
RDH12Retinol dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (315 aa)
ENSUAMP00000012555Uncharacterized protein. (284 aa)
HMGCR3-hydroxy-3-methylglutaryl coenzyme A reductase. (897 aa)
HSD17B14Hydroxysteroid 17-beta dehydrogenase 14. (336 aa)
DHDHDihydrodiol dehydrogenase. (335 aa)
ENSUAMP00000013499Uncharacterized protein. (109 aa)
SDR9C7Short chain dehydrogenase/reductase family 9C member 7; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (313 aa)
RDH16Retinol dehydrogenase 16; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (317 aa)
MDH2Malate dehydrogenase. (338 aa)
G6PDGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (572 aa)
SRD5A23-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (254 aa)
ADH4Alcohol dehydrogenase 4 (class II), pi polypeptide. (380 aa)
ENSUAMP00000014798S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (374 aa)
ENSUAMP00000014859Iso_dh domain-containing protein. (372 aa)
BDH13-hydroxybutyrate dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (343 aa)
GRHPRGlyoxylate and hydroxypyruvate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (328 aa)
ENSUAMP00000016165Uncharacterized protein. (565 aa)
ME1Malic enzyme. (580 aa)
MDH1Malate dehydrogenase. (321 aa)
GPD1Glycerol-3-phosphate dehydrogenase [NAD(+)]. (349 aa)
ENSUAMP00000017482Uncharacterized protein. (228 aa)
HSD3B7Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7; Belongs to the 3-beta-HSD family. (369 aa)
RDH5Retinol dehydrogenase 5; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (318 aa)
URB2URB2 ribosome biogenesis homolog. (1521 aa)
ENSUAMP00000019553Uncharacterized protein. (82 aa)
ENSUAMP00000019554Uncharacterized protein. (434 aa)
ME2Malic enzyme. (547 aa)
AKR1D1Aldo-keto reductase family 1 member D1. (323 aa)
ENSUAMP00000020051Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (445 aa)
DHRS13Dehydrogenase/reductase 13. (374 aa)
ENSUAMP00000020160Uncharacterized protein. (375 aa)
ENSUAMP00000020162Uncharacterized protein. (830 aa)
IDH3GIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (395 aa)
NSDHLNAD(P) dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family. (361 aa)
HSD11B1Hydroxysteroid 11-beta dehydrogenase 1. (292 aa)
ENSUAMP00000021877Uncharacterized protein. (80 aa)
SPRSepiapterin reductase. (267 aa)
LDHDLactate dehydrogenase D. (485 aa)
RDH13Retinol dehydrogenase 13; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (334 aa)
IMPDH2Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (514 aa)
ENSUAMP00000022722Uncharacterized protein. (223 aa)
CBR3Carbonyl reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (277 aa)
IDH3AIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (380 aa)
RDH8Retinol dehydrogenase 8; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (312 aa)
LDHAL6BL-lactate dehydrogenase. (236 aa)
ENSUAMP00000024468UEV domain-containing protein. (76 aa)
ENSUAMP00000024469UEV domain-containing protein; Belongs to the LDH/MDH superfamily. (377 aa)
ENSUAMP00000024472Ldh_1_C domain-containing protein. (55 aa)
ENSUAMP00000024473L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (179 aa)
LDHAL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (332 aa)
ENSUAMP00000024543Uncharacterized protein. (554 aa)
ENSUAMP00000024577Uncharacterized protein. (146 aa)
ZADH2Zinc binding alcohol dehydrogenase domain containing 2. (377 aa)
DHRS9Dehydrogenase/reductase 9; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (319 aa)
DHRS3Dehydrogenase/reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa)
CBR4Carbonyl reductase 4. (237 aa)
ENSUAMP00000026055Ldh_1_C domain-containing protein. (101 aa)
ENSUAMP00000027042ADH_N domain-containing protein. (95 aa)
CTBP1C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (421 aa)
FAM114A2Family with sequence similarity 114 member A2. (472 aa)
ENSUAMP00000027938Uncharacterized protein. (110 aa)
ENSUAMP00000028100Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (330 aa)
HSD17B6Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (314 aa)
HPGD15-hydroxyprostaglandin dehydrogenase. (172 aa)
HIBADH3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (336 aa)
KCNAB1Potassium voltage-gated channel subfamily A member regulatory beta subunit 1. (318 aa)
ENSUAMP00000030237Uncharacterized protein. (68 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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