STRINGSTRING
ENSUAMP00000016019 ENSUAMP00000016019 MKNK2 MKNK2 ULK3 ULK3 SGK2 SGK2 ENSUAMP00000000198 ENSUAMP00000000198 DYRK3 DYRK3 MAPKAPK2 MAPKAPK2 ENSUAMP00000000381 ENSUAMP00000000381 BAK1 BAK1 TSSK6 TSSK6 HIPK2 HIPK2 LATS2 LATS2 DGKQ DGKQ DYRK1B DYRK1B MAPKAPK5 MAPKAPK5 DYRK1A DYRK1A MYO3B MYO3B DYRK4 DYRK4 GALK1 GALK1 H3F3B H3F3B ENSUAMP00000004127 ENSUAMP00000004127 MKNK1 MKNK1 PRKCQ PRKCQ PDGFB PDGFB ENSUAMP00000004964 ENSUAMP00000004964 ENSUAMP00000005048 ENSUAMP00000005048 ENSUAMP00000005084 ENSUAMP00000005084 MAP4K1 MAP4K1 TLK1 TLK1 AURKB AURKB ENSUAMP00000034416 ENSUAMP00000034416 PRPF4B PRPF4B DCLK3 DCLK3 RPS6KB2 RPS6KB2 GRK2 GRK2 TTBK1 TTBK1 LATS1 LATS1 ENSUAMP00000006938 ENSUAMP00000006938 PKN3 PKN3 ENSUAMP00000007378 ENSUAMP00000007378 PRKCB PRKCB SGK1 SGK1 ENSUAMP00000008298 ENSUAMP00000008298 CAMKV CAMKV PRKCD PRKCD ENSUAMP00000008823 ENSUAMP00000008823 ERN1 ERN1 STK38L STK38L TTK TTK ENSUAMP00000009120 ENSUAMP00000009120 PRKD1 PRKD1 ENSUAMP00000009775 ENSUAMP00000009775 DCLK1 DCLK1 PRKCA PRKCA AKT1 AKT1 CDC7 CDC7 PRKDC PRKDC MAP3K13 MAP3K13 RPS6KA2 RPS6KA2 AKT3 AKT3 AURKC AURKC GSK3B GSK3B MAST1 MAST1 MAPK1 MAPK1 MAST2 MAST2 ILK ILK NEK6 NEK6 CAB39 CAB39 PRKAA1 PRKAA1 ENSUAMP00000032511 ENSUAMP00000032511 MAPK13 MAPK13 SYK SYK ENSUAMP00000031986 ENSUAMP00000031986 ENSUAMP00000031985 ENSUAMP00000031985 TSSK4 TSSK4 RICTOR RICTOR ENSUAMP00000031131 ENSUAMP00000031131 MAP3K12 MAP3K12 DYRK2 DYRK2 RPS6KA3 RPS6KA3 RPS6KA4 RPS6KA4 ENSUAMP00000030353 ENSUAMP00000030353 CSNK1G1 CSNK1G1 IKBKE IKBKE CDK5 CDK5 MAPK9 MAPK9 TLK2 TLK2 ENSUAMP00000028373 ENSUAMP00000028373 ENSUAMP00000028141 ENSUAMP00000028141 HIPK3 HIPK3 STK32B STK32B GAS6 GAS6 NTRK2 NTRK2 HIPK1 HIPK1 TSSK1B TSSK1B STK32C STK32C MAST4 MAST4 NEK7 NEK7 PKN1 PKN1 PCK1 PCK1 H3-3A H3-3A ENSUAMP00000025300 ENSUAMP00000025300 CSNK1A1 CSNK1A1 RPS6KA6 RPS6KA6 SBK2 SBK2 ENSUAMP00000024788 ENSUAMP00000024788 VRK1 VRK1 PAK2 PAK2 CDK1 CDK1 AURKA AURKA NLK NLK ENSUAMP00000023165 ENSUAMP00000023165 ENSUAMP00000023048 ENSUAMP00000023048 SGK3 SGK3 ENSUAMP00000023019 ENSUAMP00000023019 STK4 STK4 RPS6KB1 RPS6KB1 ENSUAMP00000022273 ENSUAMP00000022273 ULK1 ULK1 PRKD2 PRKD2 STK32A STK32A CSNK2A2 CSNK2A2 CAMK1G CAMK1G ENSUAMP00000020667 ENSUAMP00000020667 IKBKB IKBKB ENSUAMP00000020485 ENSUAMP00000020485 PRKCG PRKCG SBK1 SBK1 RIPK1 RIPK1 MTOR MTOR PRKCI PRKCI ROCK1 ROCK1 ENSUAMP00000018638 ENSUAMP00000018638 CLK1 CLK1 CHEK2 CHEK2 CAMK1 CAMK1 SMTNL1 SMTNL1 CSNK1D CSNK1D PINK1 PINK1 RPS6KA1 RPS6KA1 MARK3 MARK3 ENSUAMP00000015215 ENSUAMP00000015215 ENSUAMP00000018470 ENSUAMP00000018470 TBK1 TBK1 SMG1 SMG1 MAST3 MAST3 RPS6KA5 RPS6KA5 MAPKAPK3 MAPKAPK3 ENSUAMP00000017468 ENSUAMP00000017468 MAPK12 MAPK12 TGFBR1 TGFBR1 TNKS TNKS PDPK1 PDPK1 LRRK2 LRRK2 PRKAA2 PRKAA2 MAP3K10 MAP3K10 AKT2 AKT2 HIPK4 HIPK4 STK38 STK38 VRK3 VRK3 CHUK CHUK ENSUAMP00000036314 ENSUAMP00000036314 ENSUAMP00000036253 ENSUAMP00000036253 UHMK1 UHMK1 ENSUAMP00000035755 ENSUAMP00000035755 ENSUAMP00000035681 ENSUAMP00000035681
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSUAMP00000016019Uncharacterized protein. (711 aa)
MKNK2MAPK interacting serine/threonine kinase 2; Belongs to the protein kinase superfamily. (463 aa)
ULK3Unc-51 like kinase 3. (537 aa)
SGK2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (367 aa)
ENSUAMP00000000198Uncharacterized protein. (238 aa)
DYRK3Dual specificity tyrosine phosphorylation regulated kinase 3. (551 aa)
MAPKAPK2MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (387 aa)
ENSUAMP00000000381Uncharacterized protein. (476 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
TSSK6Testis specific serine kinase 6; Belongs to the protein kinase superfamily. (273 aa)
HIPK2Homeodomain interacting protein kinase 2. (1200 aa)
LATS2Non-specific serine/threonine protein kinase. (1084 aa)
DGKQDiacylglycerol kinase. (950 aa)
DYRK1BDual specificity tyrosine phosphorylation regulated kinase 1B. (614 aa)
MAPKAPK5MAPK activated protein kinase 5. (456 aa)
DYRK1ADual specificity tyrosine phosphorylation regulated kinase 1A. (754 aa)
MYO3BMyosin IIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1278 aa)
DYRK4Dual specificity tyrosine phosphorylation regulated kinase 4. (519 aa)
GALK1Galactokinase 1. (392 aa)
H3F3BHistone H3; Belongs to the histone H3 family. (136 aa)
ENSUAMP00000004127PX domain-containing protein. (66 aa)
MKNK1MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (415 aa)
PRKCQProtein kinase C theta. (526 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
ENSUAMP00000004964Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1696 aa)
ENSUAMP00000005048Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (241 aa)
ENSUAMP00000005084Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (385 aa)
MAP4K1Mitogen-activated protein kinase kinase kinase kinase 1; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (851 aa)
TLK1Tousled like kinase 1. (723 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (344 aa)
ENSUAMP00000034416Non-specific serine/threonine protein kinase. (686 aa)
PRPF4BPre-mRNA processing factor 4B. (1041 aa)
DCLK3Doublecortin like kinase 3. (589 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (482 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (647 aa)
TTBK1Tau tubulin kinase 1. (1288 aa)
LATS1Uncharacterized protein. (1012 aa)
ENSUAMP00000006938Uncharacterized protein. (133 aa)
PKN3Protein kinase N3. (900 aa)
ENSUAMP00000007378Protein kinase domain-containing protein. (111 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (651 aa)
SGK1Serum/glucocorticoid regulated kinase 1. (437 aa)
ENSUAMP00000008298AGC-kinase C-terminal domain-containing protein. (89 aa)
CAMKVCaM kinase like vesicle associated. (473 aa)
PRKCDProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
ENSUAMP00000008823TAN domain-containing protein. (111 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1. (978 aa)
STK38LNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (412 aa)
TTKTTK protein kinase. (853 aa)
ENSUAMP00000009120Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (436 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (848 aa)
ENSUAMP00000009775C2 domain-containing protein. (151 aa)
DCLK1Doublecortin like kinase 1. (740 aa)
PRKCAProtein kinase C alpha; Belongs to the protein kinase superfamily. (484 aa)
AKT1Non-specific serine/threonine protein kinase. (572 aa)
CDC7Cell division cycle 7. (575 aa)
PRKDCProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (3341 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (966 aa)
RPS6KA2Ribosomal protein S6 kinase. (753 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
AURKCAurora kinase C; Belongs to the protein kinase superfamily. (307 aa)
GSK3BGlycogen synthase kinase 3 beta. (335 aa)
MAST1Microtubule associated serine/threonine kinase 1. (1571 aa)
MAPK1Mitogen-activated protein kinase. (364 aa)
MAST2Microtubule associated serine/threonine kinase 2. (1820 aa)
ILKIntegrin linked kinase. (503 aa)
NEK6NIMA related kinase 6; Belongs to the protein kinase superfamily. (291 aa)
CAB39Calcium binding protein 39. (341 aa)
PRKAA1Non-specific serine/threonine protein kinase. (559 aa)
ENSUAMP00000032511Protein kinase domain-containing protein. (132 aa)
MAPK13Mitogen-activated protein kinase. (366 aa)
SYKSpleen associated tyrosine kinase. (638 aa)
ENSUAMP00000031986Uncharacterized protein. (575 aa)
ENSUAMP00000031985Uncharacterized protein. (493 aa)
TSSK4Testis specific serine kinase 4. (338 aa)
RICTORRPTOR independent companion of MTOR complex 2. (1762 aa)
ENSUAMP00000031131Protein kinase domain-containing protein. (264 aa)
MAP3K12Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (892 aa)
DYRK2Dual specificity tyrosine phosphorylation regulated kinase 2. (601 aa)
RPS6KA3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (488 aa)
RPS6KA4Ribosomal protein S6 kinase. (772 aa)
ENSUAMP00000030353C2 domain-containing protein. (165 aa)
CSNK1G1Casein kinase 1 gamma 1; Belongs to the protein kinase superfamily. (499 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (693 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
MAPK9Mitogen-activated protein kinase. (433 aa)
TLK2Tousled like kinase 2. (690 aa)
ENSUAMP00000028373Uncharacterized protein. (68 aa)
ENSUAMP00000028141Uncharacterized protein. (225 aa)
HIPK3Homeodomain interacting protein kinase 3. (1221 aa)
STK32BProtein kinase domain-containing protein. (307 aa)
GAS6Growth arrest specific 6. (655 aa)
NTRK2Tyrosine-protein kinase receptor. (800 aa)
HIPK1Homeodomain interacting protein kinase 1. (822 aa)
TSSK1BTestis specific serine kinase 1B; Belongs to the protein kinase superfamily. (455 aa)
STK32CSerine/threonine kinase 32C; Belongs to the protein kinase superfamily. (447 aa)
MAST4Microtubule associated serine/threonine kinase family member 4. (2431 aa)
NEK7NIMA related kinase 7; Belongs to the protein kinase superfamily. (302 aa)
PKN1Protein kinase domain-containing protein. (739 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
H3-3AHistone domain-containing protein. (142 aa)
ENSUAMP00000025300Non-specific serine/threonine protein kinase. (254 aa)
CSNK1A1Casein kinase 1 alpha 1; Belongs to the protein kinase superfamily. (365 aa)
RPS6KA6Non-specific serine/threonine protein kinase. (686 aa)
SBK2SH3 domain binding kinase family member 2; Belongs to the protein kinase superfamily. (350 aa)
ENSUAMP00000024788Protein kinase domain-containing protein. (102 aa)
VRK1VRK serine/threonine kinase 1; Belongs to the protein kinase superfamily. (395 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
CDK1Cyclin dependent kinase 1. (305 aa)
AURKAAurora kinase A; Belongs to the protein kinase superfamily. (405 aa)
NLKMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa)
ENSUAMP00000023165Protein kinase domain-containing protein. (270 aa)
ENSUAMP00000023048PB1 domain-containing protein. (123 aa)
SGK3Serum/glucocorticoid regulated kinase family member 3; Belongs to the protein kinase superfamily. (412 aa)
ENSUAMP00000023019Uncharacterized protein. (61 aa)
STK4Serine/threonine kinase 4. (487 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (524 aa)
ENSUAMP00000022273AGC-kinase C-terminal domain-containing protein. (60 aa)
ULK1Unc-51 like autophagy activating kinase 1. (974 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (840 aa)
STK32ASerine/threonine kinase 32A; Belongs to the protein kinase superfamily. (406 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (322 aa)
CAMK1GCalcium/calmodulin dependent protein kinase IG; Belongs to the protein kinase superfamily. (476 aa)
ENSUAMP00000020667OSR1_C domain-containing protein. (287 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (703 aa)
ENSUAMP00000020485Protein kinase domain-containing protein. (108 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (714 aa)
SBK1Serine/threonine-protein kinase SBK1; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (363 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (550 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2523 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (587 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1365 aa)
ENSUAMP00000018638Uncharacterized protein. (269 aa)
CLK1CDC like kinase 1; Belongs to the protein kinase superfamily. (484 aa)
CHEK2Checkpoint kinase 2. (530 aa)
CAMK1Calcium/calmodulin dependent protein kinase I; Belongs to the protein kinase superfamily. (370 aa)
SMTNL1Smoothelin like 1. (465 aa)
CSNK1DCasein kinase 1 delta; Belongs to the protein kinase superfamily. (428 aa)
PINK1PTEN induced kinase 1. (602 aa)
RPS6KA1Ribosomal protein S6 kinase. (836 aa)
MARK3Non-specific serine/threonine protein kinase. (753 aa)
ENSUAMP00000015215Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (467 aa)
ENSUAMP00000018470Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (298 aa)
TBK1TANK binding kinase 1. (709 aa)
SMG1SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family. (3522 aa)
MAST3Microtubule associated serine/threonine kinase 3. (1347 aa)
RPS6KA5Ribosomal protein S6 kinase. (798 aa)
MAPKAPK3MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (384 aa)
ENSUAMP00000017468Protein kinase domain-containing protein. (85 aa)
MAPK12Mitogen-activated protein kinase 12. (373 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (501 aa)
TNKSPoly [ADP-ribose] polymerase. (908 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (531 aa)
LRRK2Leucine rich repeat kinase 2. (1967 aa)
PRKAA2Non-specific serine/threonine protein kinase. (525 aa)
MAP3K10Mitogen-activated protein kinase kinase kinase. (881 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
HIPK4Homeodomain interacting protein kinase 4. (616 aa)
STK38Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (419 aa)
VRK3VRK serine/threonine kinase 3. (483 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
ENSUAMP00000036314Protein kinase domain-containing protein. (321 aa)
ENSUAMP00000036253Protein kinase domain-containing protein. (66 aa)
UHMK1U2AF homology motif kinase 1. (419 aa)
ENSUAMP00000035755Protein kinase domain-containing protein. (105 aa)
ENSUAMP00000035681Protein kinase domain-containing protein. (217 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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