76 items (Ursus americanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FBXL5	F-box and leucine rich repeat protein 5. (691 aa)
	TRIM21	Tripartite motif containing 21. (469 aa)
	FBXO4	F-box protein 4. (303 aa)
	ENSUAMP00000001958	CS domain-containing protein. (97 aa)
	FBXW5	F-box and WD repeat domain containing 5. (725 aa)
	NCCRP1	Non-specific cytotoxic cell receptor protein 1 homolog (zebrafish). (262 aa)
	FBXO42	F-box protein 42. (401 aa)
	ENSUAMP00000004203	CS domain-containing protein. (109 aa)
	ENSUAMP00000004242	Uncharacterized protein. (138 aa)
	TRAF7	TNF receptor associated factor 7. (670 aa)
	USP47	Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1275 aa)
	FBXL6	F-box and leucine rich repeat protein 6. (533 aa)
	ENSUAMP00000007446	WD_REPEATS_REGION domain-containing protein. (380 aa)
	TMEM183A	Transmembrane protein 183A. (376 aa)
	CMIP	C-Maf inducing protein. (764 aa)
	CUL5	Cullin 5; Belongs to the cullin family. (662 aa)
	FBH1	F-box DNA helicase 1. (1046 aa)
	FBXO9	F-box protein 9. (435 aa)
	FBXL17	F-box and leucine rich repeat protein 17. (662 aa)
	FBXL15	F-box and leucine rich repeat protein 15. (300 aa)
	ENSUAMP00000010403	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (66 aa)
	ENSUAMP00000010478	Uncharacterized protein. (91 aa)
	GSE1	Gse1 coiled-coil protein. (1086 aa)
	DMAC2	Distal membrane arm assembly complex 2. (289 aa)
	ENSUAMP00000012590	Uncharacterized protein. (206 aa)
	FBXO25	F-box protein 25. (366 aa)
	FBXO17	F-box protein 17. (277 aa)
	FBXO48	F-box protein 48. (155 aa)
	FBXL16	F-box and leucine rich repeat protein 16. (524 aa)
	FBXL18	F-box and leucine rich repeat protein 18. (747 aa)
	CCNF	Cyclin F; Belongs to the cyclin family. (776 aa)
	SPSB4	SplA/ryanodine receptor domain and SOCS box containing 4. (273 aa)
	SPSB3	SplA/ryanodine receptor domain and SOCS box containing 3. (379 aa)
	ENSUAMP00000017316	F-box domain-containing protein. (71 aa)
	CKS1B	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
	FBXO31	F-box protein 31. (542 aa)
	ENSUAMP00000019861	F-box domain-containing protein. (51 aa)
	ENSUAMP00000019862	Uncharacterized protein. (350 aa)
	LRRC29	Leucine rich repeat containing 29. (166 aa)
	ENSUAMP00000020585	Uncharacterized protein. (252 aa)
	CKS2	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (74 aa)
	FBXL14	F-box and leucine rich repeat protein 14. (420 aa)
	FBXL12	F-box and leucine rich repeat protein 12. (316 aa)
	ENSUAMP00000023965	F-box domain-containing protein. (94 aa)
	FBXO2	F-box protein 2. (294 aa)
	FBXO44	F-box protein 44. (219 aa)
	FBXO6	F-box protein 6. (270 aa)
	SKP2	S-phase kinase associated protein 2. (436 aa)
	FBXL3	F-box and leucine rich repeat protein 3. (428 aa)
	FBXW7	F-box and WD repeat domain containing 7. (627 aa)
	FBXL7	F-box and leucine rich repeat protein 7. (457 aa)
	ENSUAMP00000027679	Uncharacterized protein. (51 aa)
	FBXO27	F-box protein 27. (279 aa)
	FBXO32	F-box protein 32. (353 aa)
	FBXL4	F-box and leucine rich repeat protein 4. (453 aa)
	DAW1	Dynein assembly factor with WD repeats 1. (414 aa)
	FBXO39	F-box protein 39. (443 aa)
	FBXL2	F-box and leucine rich repeat protein 2. (422 aa)
	CUL1	Cullin 1; Belongs to the cullin family. (742 aa)
	ENSUAMP00000029036	Uncharacterized protein. (233 aa)
	CUL2	Cullin 2; Belongs to the cullin family. (745 aa)
	FBXO7	F-box protein 7. (523 aa)
	ARIH1	RBR-type E3 ubiquitin transferase. (448 aa)
	FBXW4	F-box and WD repeat domain containing 4. (595 aa)
	BTRC	Beta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
	ENSUAMP00000031423	Uncharacterized protein. (273 aa)
	ENSUAMP00000031424	B30.2/SPRY domain-containing protein. (268 aa)
	FBXO45	F-box protein 45. (303 aa)
	FBXL19	F-box and leucine rich repeat protein 19. (703 aa)
	ENSUAMP00000031825	FBA domain-containing protein. (158 aa)
	FBXW11	F-box and WD repeat domain containing 11. (543 aa)
	FBXO33	F-box protein 33. (556 aa)
	ENSUAMP00000033960	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (58 aa)
	FBXL20	F-box and leucine rich repeat protein 20. (436 aa)
	FBXO15	F-box protein 15. (436 aa)
	SPSB2	SplA/ryanodine receptor domain and SOCS box containing 2. (263 aa)

Your Current Organism:

Ursus americanus

NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARIH1	CUL1	ENSUAMP00000030096	ENSUAMP00000028874	RBR-type E3 ubiquitin transferase.	Cullin 1; Belongs to the cullin family.	0.874
ARIH1	CUL2	ENSUAMP00000030096	ENSUAMP00000029166	RBR-type E3 ubiquitin transferase.	Cullin 2; Belongs to the cullin family.	0.524
ARIH1	ENSUAMP00000027679	ENSUAMP00000030096	ENSUAMP00000027679	RBR-type E3 ubiquitin transferase.	Uncharacterized protein.	0.874
ARIH1	SKP2	ENSUAMP00000030096	ENSUAMP00000025997	RBR-type E3 ubiquitin transferase.	S-phase kinase associated protein 2.	0.603
BTRC	CCNF	ENSUAMP00000031418	ENSUAMP00000016434	Beta-transducin repeat containing E3 ubiquitin protein ligase.	Cyclin F; Belongs to the cyclin family.	0.426
BTRC	CUL1	ENSUAMP00000031418	ENSUAMP00000028874	Beta-transducin repeat containing E3 ubiquitin protein ligase.	Cullin 1; Belongs to the cullin family.	0.987
BTRC	ENSUAMP00000007446	ENSUAMP00000031418	ENSUAMP00000007446	Beta-transducin repeat containing E3 ubiquitin protein ligase.	WD_REPEATS_REGION domain-containing protein.	0.440
BTRC	ENSUAMP00000012590	ENSUAMP00000031418	ENSUAMP00000012590	Beta-transducin repeat containing E3 ubiquitin protein ligase.	Uncharacterized protein.	0.929
BTRC	ENSUAMP00000027679	ENSUAMP00000031418	ENSUAMP00000027679	Beta-transducin repeat containing E3 ubiquitin protein ligase.	Uncharacterized protein.	0.987
BTRC	FBXO2	ENSUAMP00000031418	ENSUAMP00000024523	Beta-transducin repeat containing E3 ubiquitin protein ligase.	F-box protein 2.	0.959
BTRC	FBXO4	ENSUAMP00000031418	ENSUAMP00000000932	Beta-transducin repeat containing E3 ubiquitin protein ligase.	F-box protein 4.	0.950
BTRC	FBXO44	ENSUAMP00000031418	ENSUAMP00000024524	Beta-transducin repeat containing E3 ubiquitin protein ligase.	F-box protein 44.	0.425
BTRC	FBXO6	ENSUAMP00000031418	ENSUAMP00000024526	Beta-transducin repeat containing E3 ubiquitin protein ligase.	F-box protein 6.	0.425
BTRC	FBXW11	ENSUAMP00000031418	ENSUAMP00000032203	Beta-transducin repeat containing E3 ubiquitin protein ligase.	F-box and WD repeat domain containing 11.	0.986
BTRC	FBXW7	ENSUAMP00000031418	ENSUAMP00000027479	Beta-transducin repeat containing E3 ubiquitin protein ligase.	F-box and WD repeat domain containing 7.	0.917
BTRC	SKP2	ENSUAMP00000031418	ENSUAMP00000025997	Beta-transducin repeat containing E3 ubiquitin protein ligase.	S-phase kinase associated protein 2.	0.969
BTRC	USP47	ENSUAMP00000031418	ENSUAMP00000007347	Beta-transducin repeat containing E3 ubiquitin protein ligase.	Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family.	0.593
CCNF	BTRC	ENSUAMP00000016434	ENSUAMP00000031418	Cyclin F; Belongs to the cyclin family.	Beta-transducin repeat containing E3 ubiquitin protein ligase.	0.426
CCNF	CKS1B	ENSUAMP00000016434	ENSUAMP00000018064	Cyclin F; Belongs to the cyclin family.	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	0.605
CCNF	CKS2	ENSUAMP00000016434	ENSUAMP00000020627	Cyclin F; Belongs to the cyclin family.	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	0.605