STRINGSTRING
ENSUAMP00000000316 ENSUAMP00000000316 LHX5 LHX5 TSKU TSKU ENSUAMP00000000397 ENSUAMP00000000397 ENSUAMP00000001245 ENSUAMP00000001245 HOXC10 HOXC10 ENSUAMP00000001992 ENSUAMP00000001992 PROX1 PROX1 ENSUAMP00000002297 ENSUAMP00000002297 ENSUAMP00000003176 ENSUAMP00000003176 ISL1 ISL1 DBX1 DBX1 NKX6-1 NKX6-1 CNTN2 CNTN2 FAIM2 FAIM2 ENSUAMP00000006467 ENSUAMP00000006467 SEMA3E SEMA3E ENSUAMP00000006989 ENSUAMP00000006989 INHBA INHBA BTG2 BTG2 PTCH1 PTCH1 PLXNA1 PLXNA1 ENSUAMP00000009098 ENSUAMP00000009098 TTLL1 TTLL1 DLX1 DLX1 DLX2 DLX2 ENSUAMP00000009377 ENSUAMP00000009377 HES1 HES1 SOX4 SOX4 TTC36 TTC36 DCLK1 DCLK1 ENSUAMP00000010093 ENSUAMP00000010093 ASCL1 ASCL1 NPY NPY ENSUAMP00000010461 ENSUAMP00000010461 DCX DCX MPP5 MPP5 TOX TOX FOXN4 FOXN4 ENSUAMP00000011478 ENSUAMP00000011478 PHOX2B PHOX2B SCN1B SCN1B ENSUAMP00000013193 ENSUAMP00000013193 LHX8 LHX8 ENSUAMP00000013631 ENSUAMP00000013631 PLXNA3 PLXNA3 ENSUAMP00000015361 ENSUAMP00000015361 NR4A2 NR4A2 NHLH1 NHLH1 MAP2 MAP2 PAFAH1B1 PAFAH1B1 TTC21B TTC21B DMRT3 DMRT3 LHX3 LHX3 ELAVL4 ELAVL4 ENSUAMP00000017677 ENSUAMP00000017677 OGDH OGDH NIN NIN ENSUAMP00000018188 ENSUAMP00000018188 GSX2 GSX2 ZSWIM4 ZSWIM4 SLC4A10 SLC4A10 SECISBP2 SECISBP2 DLL4 DLL4 NRP2 NRP2 LHX4 LHX4 ZSWIM5 ZSWIM5 ENSUAMP00000021522 ENSUAMP00000021522 ENSUAMP00000021529 ENSUAMP00000021529 OLIG3 OLIG3 EMX1 EMX1 ENSUAMP00000023660 ENSUAMP00000023660 CDH11 CDH11 RORA RORA EPHB3 EPHB3 OTP OTP TBX20 TBX20 TBR1 TBR1 ENSUAMP00000026268 ENSUAMP00000026268 B4GALT5 B4GALT5 TULP3 TULP3 SCYL1 SCYL1 NTRK2 NTRK2 ABT1 ABT1 SMO SMO ENSUAMP00000027842 ENSUAMP00000027842 ENSUAMP00000027843 ENSUAMP00000027843 MYCBP2 MYCBP2 NHLH2 NHLH2 ZNF335 ZNF335 CEND1 CEND1 SIN3A SIN3A CDK5 CDK5 NDEL1 NDEL1 SLIT2 SLIT2 EPHB1 EPHB1 GSX1 GSX1 CBLN1 CBLN1 ENSUAMP00000031091 ENSUAMP00000031091 LBX1 LBX1 FBXO45 FBXO45 NKX2-1 NKX2-1 LRRC45 LRRC45 GBX2 GBX2 CSF1R CSF1R GLI3 GLI3 ISL2 ISL2 NKX2-2 NKX2-2 FEZF2 FEZF2 BMPR1B BMPR1B ENSUAMP00000032923 ENSUAMP00000032923 C21orf91 C21orf91 HOXD10 HOXD10 ARHGAP35 ARHGAP35 UQCRQ UQCRQ PEX5 PEX5 GBA2 GBA2 WNT1 WNT1 PHOX2A PHOX2A BMPR1A BMPR1A LHX1 LHX1 RAPGEF2 RAPGEF2 ENSUAMP00000036326 ENSUAMP00000036326 NR2E1 NR2E1 SCYL2 SCYL2 LDB1 LDB1 OLIG2 OLIG2 ZMIZ1 ZMIZ1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSUAMP00000000316Homeobox domain-containing protein. (280 aa)
LHX5LIM homeobox 5. (402 aa)
TSKUTsukushi, small leucine rich proteoglycan. (351 aa)
ENSUAMP00000000397Paired domain-containing protein. (216 aa)
ENSUAMP00000001245CTF/NF-I domain-containing protein. (195 aa)
HOXC10Homeobox C10. (342 aa)
ENSUAMP00000001992Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (371 aa)
PROX1Prospero homeobox 1. (737 aa)
ENSUAMP00000002297Eph LBD domain-containing protein. (286 aa)
ENSUAMP00000003176Uncharacterized protein. (335 aa)
ISL1ISL LIM homeobox 1. (349 aa)
DBX1Developing brain homeobox 1. (341 aa)
NKX6-1NK6 homeobox 1. (366 aa)
CNTN2Contactin 2. (1045 aa)
FAIM2Fas apoptotic inhibitory molecule 2; Belongs to the BI1 family. (316 aa)
ENSUAMP00000006467Uncharacterized protein. (310 aa)
SEMA3ESemaphorin 3E; Belongs to the semaphorin family. (775 aa)
ENSUAMP00000006989CTF/NF-I domain-containing protein. (213 aa)
INHBAInhibin subunit beta A. (424 aa)
BTG2BTG anti-proliferation factor 2. (162 aa)
PTCH1Patched 1. (1453 aa)
PLXNA1Plexin A1. (1852 aa)
ENSUAMP00000009098C2H2-type domain-containing protein. (235 aa)
TTLL1Tubulin tyrosine ligase like 1. (423 aa)
DLX1Distal-less homeobox 1. (255 aa)
DLX2Distal-less homeobox 2. (333 aa)
ENSUAMP00000009377Uncharacterized protein. (170 aa)
HES1Hes family bHLH transcription factor 1. (259 aa)
SOX4Transcription factor SOX. (452 aa)
TTC36Tetratricopeptide repeat domain 36. (189 aa)
DCLK1Doublecortin like kinase 1. (740 aa)
ENSUAMP00000010093SUFU_C domain-containing protein. (81 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (213 aa)
NPYNeuropeptide Y. (90 aa)
ENSUAMP00000010461BHLH domain-containing protein. (178 aa)
DCXDoublecortin. (371 aa)
MPP5Membrane palmitoylated protein 5; Belongs to the MAGUK family. (675 aa)
TOXThymocyte selection associated high mobility group box. (526 aa)
FOXN4Forkhead box N4. (514 aa)
ENSUAMP00000011478Uncharacterized protein. (85 aa)
PHOX2BPaired like homeobox 2B. (289 aa)
SCN1BSodium voltage-gated channel beta subunit 1. (218 aa)
ENSUAMP00000013193Uncharacterized protein. (313 aa)
LHX8LIM homeobox 8. (357 aa)
ENSUAMP00000013631DUF1619 domain-containing protein. (248 aa)
PLXNA3Plexin A3. (1794 aa)
ENSUAMP00000015361CUB domain-containing protein. (131 aa)
NR4A2Nuclear receptor subfamily 4 group A member 2. (598 aa)
NHLH1Nescient helix-loop-helix 1. (133 aa)
MAP2Microtubule-associated protein. (1862 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)
TTC21BTetratricopeptide repeat domain 21B. (1268 aa)
DMRT3Doublesex and mab-3 related transcription factor 3. (476 aa)
LHX3LIM homeobox 3. (403 aa)
ELAVL4ELAV-like protein; Belongs to the RRM elav family. (402 aa)
ENSUAMP00000017677Uncharacterized protein; Belongs to the BI1 family. (285 aa)
OGDHOxoglutarate dehydrogenase. (1083 aa)
NINNinein. (2134 aa)
ENSUAMP00000018188LIM zinc-binding domain-containing protein. (171 aa)
GSX2GS homeobox 2. (312 aa)
ZSWIM4Zinc finger SWIM-type containing 4. (1080 aa)
SLC4A10Anion exchange protein. (855 aa)
SECISBP2SECIS binding protein 2. (842 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (716 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (851 aa)
LHX4LIM homeobox 4. (390 aa)
ZSWIM5Zinc finger SWIM-type containing 5. (1146 aa)
ENSUAMP00000021522Uncharacterized protein. (246 aa)
ENSUAMP00000021529Uncharacterized protein. (906 aa)
OLIG3Oligodendrocyte transcription factor 3. (272 aa)
EMX1Empty spiracles homeobox 1. (294 aa)
ENSUAMP00000023660Uncharacterized protein. (778 aa)
CDH11Cadherin 11; Cadherins are calcium-dependent cell adhesion proteins. (796 aa)
RORARAR related orphan receptor A. (522 aa)
EPHB3EPH receptor B3. (1000 aa)
OTPOrthopedia homeobox. (325 aa)
TBX20T-box transcription factor 20. (448 aa)
TBR1T-box brain transcription factor 1. (682 aa)
ENSUAMP00000026268Uncharacterized protein. (462 aa)
B4GALT5Beta-1,4-galactosyltransferase 5. (388 aa)
TULP3Tubby-like protein; Belongs to the TUB family. (444 aa)
SCYL1SCY1 like pseudokinase 1. (807 aa)
NTRK2Tyrosine-protein kinase receptor. (800 aa)
ABT1Activator of basal transcription 1. (269 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (788 aa)
ENSUAMP00000027842Uncharacterized protein. (99 aa)
ENSUAMP00000027843Uncharacterized protein. (119 aa)
MYCBP2MYC binding protein 2. (4749 aa)
NHLH2Nescient helix-loop-helix 2. (135 aa)
ZNF335Zinc finger protein 335. (1349 aa)
CEND1Cell cycle exit and neuronal differentiation 1. (149 aa)
SIN3ASIN3 transcription regulator family member A. (1275 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
NDEL1NudE neurodevelopment protein 1 like 1. (345 aa)
SLIT2Slit guidance ligand 2. (1450 aa)
EPHB1EPH receptor B1. (970 aa)
GSX1GS homeobox 1. (263 aa)
CBLN1Cerebellin 1 precursor. (193 aa)
ENSUAMP00000031091Uncharacterized protein. (151 aa)
LBX1Ladybird homeobox 1. (281 aa)
FBXO45F-box protein 45. (303 aa)
NKX2-1NK2 homeobox 1. (370 aa)
LRRC45Leucine rich repeat containing 45. (670 aa)
GBX2Gastrulation brain homeobox 2. (348 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (967 aa)
GLI3GLI family zinc finger 3. (1413 aa)
ISL2ISL LIM homeobox 2. (359 aa)
NKX2-2NK2 homeobox 2. (273 aa)
FEZF2FEZ family zinc finger 2. (443 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (502 aa)
ENSUAMP00000032923Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (387 aa)
C21orf91Chromosome 21 open reading frame 91. (297 aa)
HOXD10Homeobox D10. (410 aa)
ARHGAP35Rho GTPase activating protein 35. (1500 aa)
UQCRQUbiquinol-cytochrome c reductase complex III subunit VII. (82 aa)
PEX5Peroxisomal biogenesis factor 5. (640 aa)
GBA2Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide. (917 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
PHOX2APaired like homeobox 2A. (286 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
LHX1LIM homeobox 1. (406 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1516 aa)
ENSUAMP00000036326Uncharacterized protein. (630 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (385 aa)
SCYL2SCY1 like pseudokinase 2. (745 aa)
LDB1LIM domain binding 1. (411 aa)
OLIG2Oligodendrocyte transcription factor 2. (302 aa)
ZMIZ1Zinc finger MIZ-type containing 1. (1044 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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