STRINGSTRING
LTF LTF SLC8A1 SLC8A1 P2RX7 P2RX7 ACVR2B ACVR2B ATRAID ATRAID ATP2B1 ATP2B1 SLC8A3 SLC8A3 TGFB1 TGFB1 ANO6 ANO6 PKDCC PKDCC ACVR2A ACVR2A TGFB3 TGFB3 ACTN3 ACTN3 TENT5A TENT5A FZD9 FZD9 BMP2 BMP2 CCN1 CCN1 TFAP2A TFAP2A ALOX5 ALOX5 PTN PTN OSR2 OSR2 PTH PTH BMP4 BMP4 ENSUAMP00000028883 ENSUAMP00000028883 MEF2C MEF2C TMEM119 TMEM119 BMPR1B BMPR1B OSR1 OSR1 WNT10B WNT10B BMPR1A BMPR1A ISG15 ISG15 BMPR2 BMPR2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LTFLactotransferrin; Belongs to the transferrin family. (706 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (619 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (578 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (527 aa)
ATRAIDAll-trans retinoic acid induced differentiation factor. (229 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1214 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (921 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
ANO6Anoctamin. (924 aa)
PKDCCProtein kinase domain containing, cytoplasmic. (452 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (510 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (942 aa)
TENT5ATerminal nucleotidyltransferase 5A. (487 aa)
FZD9Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (561 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
CCN1Cellular communication network factor 1. (382 aa)
TFAP2ATranscription factor AP-2 alpha. (442 aa)
ALOX5Arachidonate 5-lipoxygenase. (674 aa)
PTNPleiotrophin. (218 aa)
OSR2Odd-skipped related transciption factor 2. (312 aa)
PTHParathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (115 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
ENSUAMP00000028883Uncharacterized protein. (321 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
TMEM119Transmembrane protein 119. (288 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (502 aa)
OSR1Odd-skipped related transcription factor 1. (267 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
ISG15ISG15 ubiquitin like modifier. (157 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (857 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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