STRINGSTRING
CHD7 CHD7 LHX1 LHX1 STRA6 STRA6 TYRO3 TYRO3 LRP2 LRP2 ENSUAMP00000017830 ENSUAMP00000017830 AXL AXL FGF10 FGF10 TP63 TP63 ESR1 ESR1 MERTK MERTK BAK1 BAK1 ENSUAMP00000000600 ENSUAMP00000000600
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CHD7Chromodomain helicase DNA binding protein 7. (2987 aa)
LHX1LIM homeobox 1. (406 aa)
STRA6Stimulated by retinoic acid 6. (642 aa)
TYRO3TYRO3 protein tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. (898 aa)
LRP2LDL receptor related protein 2. (4684 aa)
ENSUAMP00000017830Uncharacterized protein. (157 aa)
AXLAXL receptor tyrosine kinase. (898 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
ESR1Estrogen receptor 1. (490 aa)
MERTKMER proto-oncogene, tyrosine kinase. (818 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
ENSUAMP00000000600Uncharacterized protein. (130 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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