STRINGSTRING
ENSUAMP00000029669 ENSUAMP00000029669 ENSUAMP00000037477 ENSUAMP00000037477 CPSF2 CPSF2 SSB SSB WDR33 WDR33 ENSUAMP00000035907 ENSUAMP00000035907 ENSUAMP00000035685 ENSUAMP00000035685 CSTF2 CSTF2 ENSUAMP00000034531 ENSUAMP00000034531 INTS5 INTS5 PAPOLA PAPOLA SCAF8 SCAF8 TENT4B TENT4B TENT4A TENT4A RPRD2 RPRD2 ERI1 ERI1 HSD17B10 HSD17B10 CPSF6 CPSF6 FBLL1 FBLL1 SYMPK SYMPK RPRD1B RPRD1B INTS2 INTS2 DKC1 DKC1 LIN28B LIN28B TRNT1 TRNT1 AHCYL1 AHCYL1 ENSUAMP00000027754 ENSUAMP00000027754 ENSUAMP00000026739 ENSUAMP00000026739 ENSUAMP00000026737 ENSUAMP00000026737 APLP1 APLP1 TENT2 TENT2 LSM10 LSM10 EXOSC4 EXOSC4 INTS14 INTS14 PNPT1 PNPT1 CSTF1 CSTF1 SUPV3L1 SUPV3L1 INTS1 INTS1 CPSF7 CPSF7 TOE1 TOE1 TRMT10C TRMT10C NUDT21 NUDT21 ENSUAMP00000021449 ENSUAMP00000021449 USB1 USB1 RPRD1A RPRD1A ELAC2 ELAC2 ENSUAMP00000020766 ENSUAMP00000020766 ELAC1 ELAC1 ENSUAMP00000019749 ENSUAMP00000019749 INTS12 INTS12 LEO1 LEO1 EXOSC10 EXOSC10 POLR3K POLR3K ENSUAMP00000017360 ENSUAMP00000017360 LSM11 LSM11 SLBP SLBP ZC3H3 ZC3H3 FIP1L1 FIP1L1 INTS7 INTS7 CLP1 CLP1 MTPAP MTPAP EXOSC9 EXOSC9 PAPOLG PAPOLG ENSUAMP00000013563 ENSUAMP00000013563 EXOSC5 EXOSC5 PAF1 PAF1 ENSUAMP00000012047 ENSUAMP00000012047 EXOSC2 EXOSC2 ENSUAMP00000011451 ENSUAMP00000011451 PCF11 PCF11 ENSUAMP00000011245 ENSUAMP00000011245 CDC73 CDC73 MBLAC1 MBLAC1 ERI3 ERI3 ENSUAMP00000010057 ENSUAMP00000010057 PARN PARN CPSF4 CPSF4 ENSUAMP00000009550 ENSUAMP00000009550 CPSF4L CPSF4L CPSF3 CPSF3 ENSUAMP00000008247 ENSUAMP00000008247 ENSUAMP00000008179 ENSUAMP00000008179 NCBP2L NCBP2L ENSUAMP00000007806 ENSUAMP00000007806 CPSF1 CPSF1 ENSUAMP00000007223 ENSUAMP00000007223 APP APP ENSUAMP00000006721 ENSUAMP00000006721 NCBP1 NCBP1 EXOSC3 EXOSC3 EXOSC7 EXOSC7 ENSUAMP00000003932 ENSUAMP00000003932 ENSUAMP00000003609 ENSUAMP00000003609 ENSUAMP00000003293 ENSUAMP00000003293 TUT4 TUT4 INTS6 INTS6 ZNF473 ZNF473 FBL FBL EXOSC8 EXOSC8 LARP7 LARP7 ENSUAMP00000001017 ENSUAMP00000001017 TMEM240 TMEM240 ENSUAMP00000000194 ENSUAMP00000000194 ENSUAMP00000000192 ENSUAMP00000000192 ENSUAMP00000000088 ENSUAMP00000000088
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSUAMP00000029669Uncharacterized protein. (86 aa)
ENSUAMP0000003747740S ribosomal protein S21; Belongs to the eukaryotic ribosomal protein eS21 family. (83 aa)
CPSF2Cleavage and polyadenylation specificity factor subunit 2. (787 aa)
SSBSmall RNA binding exonuclease protection factor La. (380 aa)
WDR33WD repeat domain 33. (1336 aa)
ENSUAMP00000035907RRM domain-containing protein. (871 aa)
ENSUAMP00000035685Uncharacterized protein. (568 aa)
CSTF2Cleavage stimulation factor subunit 2. (631 aa)
ENSUAMP00000034531Uncharacterized protein. (173 aa)
INTS5Integrator complex subunit 5. (1019 aa)
PAPOLAPoly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (427 aa)
SCAF8SR-related CTD associated factor 8. (1351 aa)
TENT4BTerminal nucleotidyltransferase 4B. (677 aa)
TENT4ATerminal nucleotidyltransferase 4A. (584 aa)
RPRD2Regulation of nuclear pre-mRNA domain containing 2. (1462 aa)
ERI1Exoribonuclease 1. (269 aa)
HSD17B10Hydroxysteroid 17-beta dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (261 aa)
CPSF6Cleavage and polyadenylation specific factor 6. (499 aa)
FBLL1Fibrillarin like 1. (330 aa)
SYMPKSymplekin. (1277 aa)
RPRD1BRegulation of nuclear pre-mRNA domain containing 1B. (326 aa)
INTS2Integrator complex subunit 2. (844 aa)
DKC1Dyskerin pseudouridine synthase 1. (537 aa)
LIN28BLin-28 homolog B. (254 aa)
TRNT1tRNA nucleotidyl transferase 1; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (450 aa)
AHCYL1Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (530 aa)
ENSUAMP00000027754INT_SG_DDX_CT_C domain-containing protein. (201 aa)
ENSUAMP00000026739Uncharacterized protein. (379 aa)
ENSUAMP00000026737Uncharacterized protein. (291 aa)
APLP1Amyloid beta precursor like protein 1. (641 aa)
TENT2Terminal nucleotidyltransferase 2. (484 aa)
LSM10LSM10, U7 small nuclear RNA associated. (123 aa)
EXOSC4Exosome component 4. (245 aa)
INTS14Integrator complex subunit 14. (518 aa)
PNPT1Polyribonucleotide nucleotidyltransferase 1. (694 aa)
CSTF1Cleavage stimulation factor subunit 1. (431 aa)
SUPV3L1Suv3 like RNA helicase. (792 aa)
INTS1Integrator complex subunit 1. (2188 aa)
CPSF7Cleavage and polyadenylation specific factor 7. (477 aa)
TOE1Target of EGR1, exonuclease. (510 aa)
TRMT10CtRNA methyltransferase 10C, mitochondrial RNase P subunit. (415 aa)
NUDT21Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (229 aa)
ENSUAMP00000021449Uncharacterized protein. (194 aa)
USB1U6 snRNA phosphodiesterase; Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA 3' end-terminated with a 2',3'-cyclic phosphate; Belongs to the 2H phosphoesterase superfamily. USB1 family. (269 aa)
RPRD1ARegulation of nuclear pre-mRNA domain containing 1A. (270 aa)
ELAC2ElaC ribonuclease Z 2. (750 aa)
ENSUAMP00000020766annotation not available (193 aa)
ELAC1ElaC ribonuclease Z 1. (363 aa)
ENSUAMP00000019749Exonuclease domain-containing protein. (267 aa)
INTS12Integrator complex subunit 12. (462 aa)
LEO1LEO1 homolog, Paf1/RNA polymerase II complex component. (618 aa)
EXOSC10Exosome component 10. (867 aa)
POLR3KDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (108 aa)
ENSUAMP00000017360Uncharacterized protein. (101 aa)
LSM11LSM11, U7 small nuclear RNA associated. (335 aa)
SLBPStem-loop binding protein. (277 aa)
ZC3H3Zinc finger CCCH-type containing 3. (883 aa)
FIP1L1Factor interacting with PAPOLA and CPSF1. (516 aa)
INTS7Integrator complex subunit 7. (719 aa)
CLP1Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...] (425 aa)
MTPAPMitochondrial poly(A) polymerase. (584 aa)
EXOSC9Exosome component 9. (356 aa)
PAPOLGPoly(A) polymerase gamma. (731 aa)
ENSUAMP00000013563Uncharacterized protein. (111 aa)
EXOSC5Exosome component 5. (197 aa)
PAF1PAF1 homolog, Paf1/RNA polymerase II complex component. (528 aa)
ENSUAMP00000012047Uncharacterized protein. (83 aa)
EXOSC2Exosome component 2. (281 aa)
ENSUAMP00000011451Uncharacterized protein. (92 aa)
PCF11PCF11 cleavage and polyadenylation factor subunit. (1686 aa)
ENSUAMP00000011245Uncharacterized protein. (315 aa)
CDC73Cell division cycle 73. (519 aa)
MBLAC1Metallo-beta-lactamase domain containing 1. (269 aa)
ERI3ERI1 exoribonuclease family member 3. (369 aa)
ENSUAMP00000010057Uncharacterized protein. (89 aa)
PARNPoly(A)-specific ribonuclease. (459 aa)
CPSF4Cleavage and polyadenylation specific factor 4. (259 aa)
ENSUAMP00000009550Uncharacterized protein. (193 aa)
CPSF4LCleavage and polyadenylation specific factor 4 like. (157 aa)
CPSF3Cleavage and polyadenylation specific factor 3. (696 aa)
ENSUAMP00000008247RNase_PH domain-containing protein. (82 aa)
ENSUAMP00000008179Uncharacterized protein. (50 aa)
NCBP2LNuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (162 aa)
ENSUAMP00000007806Uncharacterized protein. (84 aa)
CPSF1Cleavage and polyadenylation specific factor 1. (1423 aa)
ENSUAMP00000007223Uncharacterized protein. (97 aa)
APPAmyloid beta precursor protein. (735 aa)
ENSUAMP00000006721INT_SG_DDX_CT_C domain-containing protein. (187 aa)
NCBP1Nuclear cap binding protein subunit 1. (790 aa)
EXOSC3Exosome component 3. (275 aa)
EXOSC7Exosome component 7. (291 aa)
ENSUAMP00000003932Uncharacterized protein. (99 aa)
ENSUAMP00000003609VWFA domain-containing protein. (166 aa)
ENSUAMP00000003293INT_SG_DDX_CT_C domain-containing protein. (212 aa)
TUT4Terminal uridylyl transferase 4. (1651 aa)
INTS6Integrator complex subunit 6. (774 aa)
ZNF473Zinc finger protein 473. (729 aa)
FBLFibrillarin. (314 aa)
EXOSC8Exosome component 8. (290 aa)
LARP7La ribonucleoprotein domain family member 7. (581 aa)
ENSUAMP00000001017Uncharacterized protein. (193 aa)
TMEM240Transmembrane protein 240. (167 aa)
ENSUAMP00000000194SLBP_RNA_bind domain-containing protein. (203 aa)
ENSUAMP00000000192Uncharacterized protein. (194 aa)
ENSUAMP00000000088VWFA domain-containing protein. (173 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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