27 items (Ursus americanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EIF3F	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (365 aa)
	CELF1	CUGBP Elav-like family member 1. (463 aa)
	EIF3C	Eukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (731 aa)
	EIF3B	Eukaryotic translation initiation factor 3 subunit B; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...] (886 aa)
	ENSUAMP00000004132	eIF2B_5 domain-containing protein. (53 aa)
	C8orf88	Chromosome 8 open reading frame 88. (119 aa)
	TRIM32	Tripartite motif containing 32. (655 aa)
	EIF4EBP3	Eukaryotic translation initiation factor 4E binding protein 3. (101 aa)
	EIF2B5	Eukaryotic translation initiation factor 2B subunit epsilon. (720 aa)
	EIF2S2	Eukaryotic translation initiation factor 2 subunit beta. (333 aa)
	EIF4EBP2	Eukaryotic translation initiation factor 4E binding protein 2. (120 aa)
	ENSUAMP00000012557	eIF-3c_N domain-containing protein. (66 aa)
	HHEX	Hematopoietically expressed homeobox. (270 aa)
	ANGEL1	Angel homolog 1. (667 aa)
	ENSUAMP00000016276	Uncharacterized protein; Belongs to the DEAD box helicase family. (661 aa)
	DDX3X	DEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. (675 aa)
	EIF4E	Eukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. (180 aa)
	SYT11	Synaptotagmin 11. (425 aa)
	TBL2	Transducin beta like 2. (446 aa)
	EIF4EBP1	Eukaryotic translation initiation factor 4E binding protein 1. (118 aa)
	FMR1	Fragile X mental retardation 1. (621 aa)
	GLE1	GLE1 RNA export mediator. (508 aa)
	LARP1	La ribonucleoprotein domain family member 1. (1102 aa)
	ZPR1	ZPR1 zinc finger. (460 aa)
	NCK1	Cytoplasmic protein. (377 aa)
	ENSUAMP00000034307	W2 domain-containing protein. (430 aa)
	POLR2G	RNA polymerase II subunit G. (241 aa)

Your Current Organism:

Ursus americanus

NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANGEL1	EIF4E	ENSUAMP00000014695	ENSUAMP00000016733	Angel homolog 1.	Eukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family.	0.495
DDX3X	EIF3B	ENSUAMP00000016569	ENSUAMP00000001616	DEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family.	Eukaryotic translation initiation factor 3 subunit B; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...]	0.639
DDX3X	EIF3C	ENSUAMP00000016569	ENSUAMP00000001487	DEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family.	Eukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]	0.538
DDX3X	EIF3F	ENSUAMP00000016569	ENSUAMP00000023018	DEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family.	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]	0.475
DDX3X	EIF4E	ENSUAMP00000016569	ENSUAMP00000016733	DEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family.	Eukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family.	0.677
DDX3X	ENSUAMP00000004132	ENSUAMP00000016569	ENSUAMP00000004132	DEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family.	eIF2B_5 domain-containing protein.	0.501
DDX3X	ENSUAMP00000012557	ENSUAMP00000016569	ENSUAMP00000012557	DEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family.	eIF-3c_N domain-containing protein.	0.538
DDX3X	ENSUAMP00000034307	ENSUAMP00000016569	ENSUAMP00000034307	DEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family.	W2 domain-containing protein.	0.501
DDX3X	GLE1	ENSUAMP00000016569	ENSUAMP00000024732	DEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family.	GLE1 RNA export mediator.	0.427
EIF2B5	EIF2S2	ENSUAMP00000006775	ENSUAMP00000008220	Eukaryotic translation initiation factor 2B subunit epsilon.	Eukaryotic translation initiation factor 2 subunit beta.	0.996
EIF2B5	EIF3B	ENSUAMP00000006775	ENSUAMP00000001616	Eukaryotic translation initiation factor 2B subunit epsilon.	Eukaryotic translation initiation factor 3 subunit B; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...]	0.455
EIF2B5	ENSUAMP00000004132	ENSUAMP00000006775	ENSUAMP00000004132	Eukaryotic translation initiation factor 2B subunit epsilon.	eIF2B_5 domain-containing protein.	0.563
EIF2B5	ENSUAMP00000034307	ENSUAMP00000006775	ENSUAMP00000034307	Eukaryotic translation initiation factor 2B subunit epsilon.	W2 domain-containing protein.	0.563
EIF2B5	ZPR1	ENSUAMP00000006775	ENSUAMP00000025580	Eukaryotic translation initiation factor 2B subunit epsilon.	ZPR1 zinc finger.	0.426
EIF2S2	EIF2B5	ENSUAMP00000008220	ENSUAMP00000006775	Eukaryotic translation initiation factor 2 subunit beta.	Eukaryotic translation initiation factor 2B subunit epsilon.	0.996
EIF2S2	EIF3B	ENSUAMP00000008220	ENSUAMP00000001616	Eukaryotic translation initiation factor 2 subunit beta.	Eukaryotic translation initiation factor 3 subunit B; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...]	0.996
EIF2S2	EIF3C	ENSUAMP00000008220	ENSUAMP00000001487	Eukaryotic translation initiation factor 2 subunit beta.	Eukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]	0.990
EIF2S2	EIF3F	ENSUAMP00000008220	ENSUAMP00000023018	Eukaryotic translation initiation factor 2 subunit beta.	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]	0.976
EIF2S2	EIF4E	ENSUAMP00000008220	ENSUAMP00000016733	Eukaryotic translation initiation factor 2 subunit beta.	Eukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family.	0.733
EIF2S2	ENSUAMP00000004132	ENSUAMP00000008220	ENSUAMP00000004132	Eukaryotic translation initiation factor 2 subunit beta.	eIF2B_5 domain-containing protein.	0.966