STRINGSTRING
ATG12 ATG12 PIGS PIGS ALOX12B ALOX12B ENSUAMP00000006463 ENSUAMP00000006463 PIGN PIGN ZDHHC12 ZDHHC12 ATG7 ATG7 ZDHHC13 ZDHHC13 ENSUAMP00000008681 ENSUAMP00000008681 ENSUAMP00000008823 ENSUAMP00000008823 ENSUAMP00000010117 ENSUAMP00000010117 ENSUAMP00000001460 ENSUAMP00000001460 ENSUAMP00000001451 ENSUAMP00000001451 ENSUAMP00000000637 ENSUAMP00000000637 LYPLA2 LYPLA2 ENSUAMP00000010908 ENSUAMP00000010908 WDR45B WDR45B ABHD10 ABHD10 PPM1A PPM1A ENSUAMP00000011081 ENSUAMP00000011081 WIPI2 WIPI2 ABHD17A ABHD17A PGAP3 PGAP3 ZDHHC14 ZDHHC14 ENSUAMP00000012252 ENSUAMP00000012252 PIGC PIGC ZDHHC16 ZDHHC16 MAP6D1 MAP6D1 ZDHHC8 ZDHHC8 ZDHHC5 ZDHHC5 APOBEC1 APOBEC1 ZDHHC2 ZDHHC2 ZDHHC22 ZDHHC22 PIGM PIGM PGAP2 PGAP2 APOM APOM LYPLAL1 LYPLAL1 PORCN PORCN ENSUAMP00000017422 ENSUAMP00000017422 SELENOK SELENOK ENSUAMP00000017764 ENSUAMP00000017764 ENSUAMP00000017779 ENSUAMP00000017779 MTTP MTTP ZDHHC24 ZDHHC24 ENSUAMP00000018878 ENSUAMP00000018878 GOLGA7B GOLGA7B NUDT22 NUDT22 PIGX PIGX LDLR LDLR PIGG PIGG ZDHHC1 ZDHHC1 DPM2 DPM2 APOLD1 APOLD1 ENSUAMP00000021267 ENSUAMP00000021267 ENSUAMP00000021688 ENSUAMP00000021688 ENSUAMP00000021856 ENSUAMP00000021856 GOLGA7 GOLGA7 ENSUAMP00000004964 ENSUAMP00000004964 OLR1 OLR1 ZDHHC23 ZDHHC23 LYPLA1 LYPLA1 ATG5 ATG5 ENSUAMP00000025262 ENSUAMP00000025262 PIGQ PIGQ APOA1 APOA1 APOC3 APOC3 APOA4 APOA4 APOA5 APOA5 ENSUAMP00000025955 ENSUAMP00000025955 GPAA1 GPAA1 CLIP3 CLIP3 PIGT PIGT DPM3 DPM3 LCAT LCAT PGAP4 PGAP4 PIGU PIGU PPT1 PPT1 DPM1 DPM1 ENSUAMP00000027456 ENSUAMP00000027456 ABHD17B ABHD17B HHAT HHAT ENSUAMP00000029510 ENSUAMP00000029510 ZDHHC21 ZDHHC21 PIGK PIGK PIGW PIGW UGCG UGCG ENSUAMP00000030569 ENSUAMP00000030569 APOE APOE ZDHHC4 ZDHHC4 ENSUAMP00000030694 ENSUAMP00000030694 ENSUAMP00000030696 ENSUAMP00000030696 ENSUAMP00000031101 ENSUAMP00000031101 NMT1 NMT1 PIGO PIGO NOTUM NOTUM CWH43 CWH43 ABHD17C ABHD17C PIK3C3 PIK3C3 GLUL GLUL APOB APOB ENSUAMP00000033423 ENSUAMP00000033423 ENSUAMP00000033437 ENSUAMP00000033437 ENSUAMP00000033589 ENSUAMP00000033589 WIPI1 WIPI1 PIGV PIGV ENSUAMP00000034502 ENSUAMP00000034502 WDR45 WDR45 PIGF PIGF ENSUAMP00000036287 ENSUAMP00000036287 ATG16L1 ATG16L1 ENSUAMP00000036830 ENSUAMP00000036830 ENSUAMP00000036833 ENSUAMP00000036833 ZDHHC19 ZDHHC19 ZDHHC20 ZDHHC20 ENSUAMP00000001751 ENSUAMP00000001751 ENSUAMP00000002128 ENSUAMP00000002128 ENSUAMP00000002134 ENSUAMP00000002134 ZDHHC17 ZDHHC17 NMT2 NMT2 ENSUAMP00000003115 ENSUAMP00000003115 ZDHHC9 ZDHHC9 ENSUAMP00000003378 ENSUAMP00000003378 ENSUAMP00000003661 ENSUAMP00000003661 ENSUAMP00000003728 ENSUAMP00000003728 ZDHHC7 ZDHHC7 ABHD13 ABHD13 ENSUAMP00000004137 ENSUAMP00000004137
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATG12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (140 aa)
PIGSPhosphatidylinositol glycan anchor biosynthesis class S. (468 aa)
ALOX12BArachidonate 12-lipoxygenase, 12R type. (699 aa)
ENSUAMP00000006463Uncharacterized protein. (89 aa)
PIGNPhosphatidylinositol glycan anchor biosynthesis class N. (710 aa)
ZDHHC12Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (295 aa)
ATG7Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (625 aa)
ZDHHC13Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (616 aa)
ENSUAMP00000008681SAM domain-containing protein. (119 aa)
ENSUAMP00000008823TAN domain-containing protein. (111 aa)
ENSUAMP00000010117Uncharacterized protein. (108 aa)
ENSUAMP00000001460Uncharacterized protein. (65 aa)
ENSUAMP00000001451Uncharacterized protein. (368 aa)
ENSUAMP00000000637Uncharacterized protein. (130 aa)
LYPLA2Lysophospholipase 2. (307 aa)
ENSUAMP00000010908Mannosyltransferase. (198 aa)
WDR45BWD repeat domain 45B. (344 aa)
ABHD10Abhydrolase domain containing 10. (266 aa)
PPM1AProtein phosphatase, Mg2+/Mn2+ dependent 1A. (382 aa)
ENSUAMP00000011081Uncharacterized protein. (147 aa)
WIPI2WD repeat domain, phosphoinositide interacting 2. (436 aa)
ABHD17AAbhydrolase domain containing 17A. (310 aa)
PGAP3Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family. (320 aa)
ZDHHC14Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (488 aa)
ENSUAMP00000012252Uncharacterized protein. (83 aa)
PIGCPhosphatidylinositol glycan anchor biosynthesis class C. (297 aa)
ZDHHC16Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (377 aa)
MAP6D1MAP6 domain containing 1. (172 aa)
ZDHHC8Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (720 aa)
ZDHHC5Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (715 aa)
APOBEC1Apolipoprotein B mRNA editing enzyme catalytic subunit 1. (244 aa)
ZDHHC2Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (322 aa)
ZDHHC22Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (263 aa)
PIGMGPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly. (425 aa)
PGAP2Post-GPI attachment to proteins 2. (254 aa)
APOMApolipoprotein M. (188 aa)
LYPLAL1Lysophospholipase like 1. (239 aa)
PORCNPorcupine O-acyltransferase; Belongs to the membrane-bound acyltransferase family. (440 aa)
ENSUAMP00000017422RGS domain-containing protein. (489 aa)
SELENOKSelenoprotein K. (91 aa)
ENSUAMP00000017764Uncharacterized protein. (365 aa)
ENSUAMP00000017779Uncharacterized protein. (124 aa)
MTTPMicrosomal triglyceride transfer protein. (811 aa)
ZDHHC24Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (284 aa)
ENSUAMP00000018878Uncharacterized protein. (140 aa)
GOLGA7BGolgin A7 family member B. (164 aa)
NUDT22Nudix hydrolase 22. (290 aa)
PIGXPhosphatidylinositol glycan anchor biosynthesis class X. (272 aa)
LDLRLow density lipoprotein receptor. (856 aa)
PIGGPhosphatidylinositol glycan anchor biosynthesis class G. (913 aa)
ZDHHC1Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (485 aa)
DPM2Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family. (117 aa)
APOLD1Apolipoprotein L domain containing 1. (246 aa)
ENSUAMP00000021267Uncharacterized protein. (74 aa)
ENSUAMP00000021688Uncharacterized protein. (297 aa)
ENSUAMP00000021856Uncharacterized protein. (78 aa)
GOLGA7Golgin A7. (129 aa)
ENSUAMP00000004964Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1696 aa)
OLR1Oxidized low density lipoprotein receptor 1. (192 aa)
ZDHHC23Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (429 aa)
LYPLA1Lysophospholipase 1. (230 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
ENSUAMP00000025262Uncharacterized protein. (82 aa)
PIGQPhosphatidylinositol glycan anchor biosynthesis class Q. (630 aa)
APOA1Apolipoprotein A1. (266 aa)
APOC3Apolipoprotein C3. (100 aa)
APOA4Apolipoprotein A4. (382 aa)
APOA5Apolipoprotein A5. (367 aa)
ENSUAMP00000025955Uncharacterized protein. (131 aa)
GPAA1Glycosylphosphatidylinositol anchor attachment 1. (666 aa)
CLIP3CAP-Gly domain containing linker protein 3. (546 aa)
PIGTPhosphatidylinositol glycan anchor biosynthesis class T. (578 aa)
DPM3Dolichol-phosphate mannosyltransferase subunit 3; Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER. Belongs to the DPM3 family. (92 aa)
LCATLecithin-cholesterol acyltransferase. (440 aa)
PGAP4Transmembrane protein 246. (403 aa)
PIGUPhosphatidylinositol glycan anchor biosynthesis class U. (297 aa)
PPT1Palmitoyl-protein thioesterase 1. (334 aa)
DPM1Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins. (260 aa)
ENSUAMP00000027456ATG7_N domain-containing protein. (72 aa)
ABHD17BAbhydrolase domain containing 17B. (288 aa)
HHATHedgehog acyltransferase; Belongs to the membrane-bound acyltransferase family. (464 aa)
ENSUAMP00000029510Uncharacterized protein. (114 aa)
ZDHHC21Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa)
PIGKGPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. (430 aa)
PIGWPhosphatidylinositol-glycan biosynthesis class W protein; Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. (502 aa)
UGCGUDP-glucose ceramide glucosyltransferase. (394 aa)
ENSUAMP00000030569Uncharacterized protein. (137 aa)
APOEApolipoprotein E. (323 aa)
ZDHHC4Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (343 aa)
ENSUAMP00000030694Glycos_transf_1 domain-containing protein. (247 aa)
ENSUAMP00000030696PIGA domain-containing protein. (147 aa)
ENSUAMP00000031101Mannosyltransferase. (561 aa)
NMT1Glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins; Belongs to the NMT family. (485 aa)
PIGOPhosphatidylinositol glycan anchor biosynthesis class O. (1089 aa)
NOTUMNotum, palmitoleoyl-protein carboxylesterase. (498 aa)
CWH43Cell wall biogenesis 43 C-terminal homolog. (698 aa)
ABHD17CAbhydrolase domain containing 17C. (207 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (746 aa)
GLULGlutamine synthetase. (484 aa)
APOBApolipoprotein B. (4436 aa)
ENSUAMP00000033423Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (187 aa)
ENSUAMP00000033437Uncharacterized protein. (181 aa)
ENSUAMP00000033589Uncharacterized protein. (121 aa)
WIPI1WD repeat domain, phosphoinositide interacting 1. (443 aa)
PIGVGPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. (493 aa)
ENSUAMP00000034502Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (315 aa)
WDR45Uncharacterized protein. (346 aa)
PIGFPhosphatidylinositol glycan anchor biosynthesis class F. (219 aa)
ENSUAMP00000036287Uncharacterized protein. (115 aa)
ATG16L1Autophagy related 16 like 1. (602 aa)
ENSUAMP00000036830WD_REPEATS_REGION domain-containing protein. (338 aa)
ENSUAMP00000036833ATG16 domain-containing protein. (113 aa)
ZDHHC19Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (307 aa)
ZDHHC20Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (302 aa)
ENSUAMP00000001751Metallophos domain-containing protein. (230 aa)
ENSUAMP00000002128Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (180 aa)
ENSUAMP00000002134Uncharacterized protein. (135 aa)
ZDHHC17Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (536 aa)
NMT2Glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins; Belongs to the NMT family. (476 aa)
ENSUAMP00000003115Uncharacterized protein. (173 aa)
ZDHHC9Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (364 aa)
ENSUAMP00000003378Uncharacterized protein. (332 aa)
ENSUAMP00000003661Uncharacterized protein. (162 aa)
ENSUAMP00000003728PIG-P domain-containing protein. (162 aa)
ZDHHC7Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (308 aa)
ABHD13Abhydrolase domain containing 13. (337 aa)
ENSUAMP00000004137Phosphatidylinositol N-acetylglucosaminyltransferase subunit P; Part of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. (132 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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