STRINGSTRING
ENSUAMP00000024290 ENSUAMP00000024290 LOX LOX ALPK3 ALPK3 PPP3CA PPP3CA NFATC4 NFATC4 FGF10 FGF10 CAV2 CAV2 PRKAR1B PRKAR1B PTCD2 PTCD2 NRAP NRAP HES1 HES1 CFL2 CFL2 SDC1 SDC1 KRT19 KRT19 MYOCD MYOCD ITGB1 ITGB1 WDR1 WDR1 KLHL40 KLHL40 PPP3CB PPP3CB HEY2 HEY2 MEGF10 MEGF10 ENSUAMP00000010858 ENSUAMP00000010858 ENSUAMP00000010867 ENSUAMP00000010867 MYLK3 MYLK3 ENSUAMP00000011392 ENSUAMP00000011392 TCAP TCAP WFIKKN2 WFIKKN2 BIN1 BIN1 POPDC2 POPDC2 ADPRH ADPRH CDON CDON BVES BVES POPDC3 POPDC3 ENSUAMP00000012393 ENSUAMP00000012393 ENSUAMP00000012403 ENSUAMP00000012403 ENSUAMP00000012729 ENSUAMP00000012729 TMEM182 TMEM182 RARB RARB FLII FLII ACTN1 ACTN1 ENSUAMP00000013482 ENSUAMP00000013482 ENSUAMP00000013919 ENSUAMP00000013919 GLMN GLMN NKX2-6 NKX2-6 APLNR APLNR CBY1 CBY1 VWA5B1 VWA5B1 RB1 RB1 RIPOR2 RIPOR2 IRX3 IRX3 ENSUAMP00000015680 ENSUAMP00000015680 MAML1 MAML1 ACADM ACADM BMP10 BMP10 KEL KEL ENSUAMP00000016162 ENSUAMP00000016162 FOXF1 FOXF1 RAMP2 RAMP2 TMEM204 TMEM204 VWA5A VWA5A FBXO40 FBXO40 LMNA LMNA ENSUAMP00000017462 ENSUAMP00000017462 ENSUAMP00000017830 ENSUAMP00000017830 ACTA2 ACTA2 ENSUAMP00000018124 ENSUAMP00000018124 CHRNB1 CHRNB1 PDGFRA PDGFRA ACTA1 ACTA1 MYOZ1 MYOZ1 SYNPO2L SYNPO2L MTOR MTOR SRF SRF DOCK5 DOCK5 ENSUAMP00000020340 ENSUAMP00000020340 KRAS KRAS MYMX MYMX ENSUAMP00000021241 ENSUAMP00000021241 ENSUAMP00000021250 ENSUAMP00000021250 BCL9 BCL9 BMP2 BMP2 ENSUAMP00000021972 ENSUAMP00000021972 SIX4 SIX4 TNNT1 TNNT1 LRRC10B LRRC10B ACTN2 ACTN2 SPAG9 SPAG9 DUPD1 DUPD1 MEF2A MEF2A ENSUAMP00000023559 ENSUAMP00000023559 LMOD3 LMOD3 ENSUAMP00000023660 ENSUAMP00000023660 ACTG2 ACTG2 MYMK MYMK KLHL41 KLHL41 RORA RORA HDGFL2 HDGFL2 ATG5 ATG5 WNT8A WNT8A MYPN MYPN WFIKKN1 WFIKKN1 H3-3A H3-3A TANC1 TANC1 ENSUAMP00000025619 ENSUAMP00000025619 LMOD1 LMOD1 ENSUAMP00000026324 ENSUAMP00000026324 ENSUAMP00000026326 ENSUAMP00000026326 MECP2 MECP2 SOX9 SOX9 NPHS1 NPHS1 TNNT3 TNNT3 R3HDM2 R3HDM2 STAC3 STAC3 SMO SMO HEY1 HEY1 LMOD2 LMOD2 ENSUAMP00000027802 ENSUAMP00000027802 ENSUAMP00000028147 ENSUAMP00000028147 ENSUAMP00000028149 ENSUAMP00000028149 SLC9A1 SLC9A1 TMOD2 TMOD2 TMOD3 TMOD3 SORT1 SORT1 BMP4 BMP4 FLNC FLNC DYSF DYSF ENSUAMP00000029003 ENSUAMP00000029003 HNRNPU HNRNPU PLEKHO1 PLEKHO1 CD9 CD9 SMARCD3 SMARCD3 MEF2C MEF2C KLF5 KLF5 ENG ENG SEMA4C SEMA4C SPEG SPEG MYL2 MYL2 CD81 CD81 CAV3 CAV3 ENSUAMP00000032138 ENSUAMP00000032138 HOMER1 HOMER1 NPNT NPNT ASB2 ASB2 TSC1 TSC1 R3HDM1 R3HDM1 BIN3 BIN3 ENSUAMP00000032677 ENSUAMP00000032677 ENSUAMP00000033199 ENSUAMP00000033199 CXADR CXADR MYOM2 MYOM2 ENSUAMP00000033631 ENSUAMP00000033631 PRKAR1A PRKAR1A ENSUAMP00000033749 ENSUAMP00000033749 NEB NEB ENSUAMP00000033750 ENSUAMP00000033750 FHL2 FHL2 MRTFB MRTFB NOTCH1 NOTCH1 HEYL HEYL ENSUAMP00000000384 ENSUAMP00000000384 ENSUAMP00000000589 ENSUAMP00000000589 ENSUAMP00000000600 ENSUAMP00000000600 MYOZ2 MYOZ2 TBX2 TBX2 VWA5B2 VWA5B2 DYRK1B DYRK1B ENSUAMP00000001962 ENSUAMP00000001962 MYOF MYOF PROX1 PROX1 GREM1 GREM1 TBX5 TBX5 CSRP2 CSRP2 ENSUAMP00000002781 ENSUAMP00000002781 GALK1 GALK1 H3F3B H3F3B ENSUAMP00000004725 ENSUAMP00000004725 ENSUAMP00000004728 ENSUAMP00000004728 ACTC1 ACTC1 ENSUAMP00000004823 ENSUAMP00000004823 MRTFA MRTFA ENSUAMP00000005311 ENSUAMP00000005311 CSRP1 CSRP1 TNNT2 TNNT2 ENSUAMP00000005541 ENSUAMP00000005541 CACNA1S CACNA1S TMOD1 TMOD1 MYORG MYORG C9orf24 C9orf24 ENSUAMP00000006515 ENSUAMP00000006515 CAPN3 CAPN3 ENSUAMP00000006638 ENSUAMP00000006638 CSRP3 CSRP3 ENSUAMP00000007554 ENSUAMP00000007554 ASF1A ASF1A SYPL2 SYPL2 ADAMTS15 ADAMTS15 IFRD2 IFRD2 ENSUAMP00000037129 ENSUAMP00000037129 MYOD1 MYOD1 PGM5 PGM5 DOCK2 DOCK2 COMP COMP ZMPSTE24 ZMPSTE24 BMPR1A BMPR1A LDB3 LDB3 ENSUAMP00000036101 ENSUAMP00000036101 TMOD4 TMOD4 PRADC1 PRADC1 WNT10B WNT10B WNT1 WNT1 MYL10 MYL10 ENSUAMP00000034792 ENSUAMP00000034792
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSUAMP00000024290Uncharacterized protein. (186 aa)
LOXLysyl oxidase. (414 aa)
ALPK3Alpha kinase 3. (1619 aa)
PPP3CASerine/threonine-protein phosphatase. (317 aa)
NFATC4Nuclear factor of activated T cells 4. (911 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
PRKAR1BProtein kinase cAMP-dependent type I regulatory subunit beta. (377 aa)
PTCD2Pentatricopeptide repeat domain 2. (427 aa)
NRAPNebulin related anchoring protein. (1729 aa)
HES1Hes family bHLH transcription factor 1. (259 aa)
CFL2Cofilin 2; Belongs to the actin-binding proteins ADF family. (148 aa)
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (301 aa)
KRT19Keratin 19; Belongs to the intermediate filament family. (407 aa)
MYOCDMyocardin. (870 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (771 aa)
WDR1WD repeat domain 1. (610 aa)
KLHL40Kelch like family member 40. (623 aa)
PPP3CBSerine/threonine-protein phosphatase. (479 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
MEGF10Multiple EGF like domains 10. (1045 aa)
ENSUAMP00000010858Myosin_tail_1 domain-containing protein. (890 aa)
ENSUAMP00000010867Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (207 aa)
MYLK3Myosin light chain kinase 3. (791 aa)
ENSUAMP00000011392Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (762 aa)
TCAPTitin-cap. (167 aa)
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2. (573 aa)
BIN1Bridging integrator 1. (686 aa)
POPDC2Popeye domain containing 2. (362 aa)
ADPRHADP-ribosylarginine hydrolase. (362 aa)
CDONCell adhesion associated, oncogene regulated. (1021 aa)
BVESBlood vessel epicardial substance. (323 aa)
POPDC3Popeye domain containing 3. (291 aa)
ENSUAMP00000012393KASH domain-containing protein. (2799 aa)
ENSUAMP00000012403Uncharacterized protein. (444 aa)
ENSUAMP00000012729RHD domain-containing protein. (481 aa)
TMEM182Transmembrane protein 182. (210 aa)
RARBRetinoic acid receptor beta. (336 aa)
FLIIFLII actin remodeling protein. (1273 aa)
ACTN1Actinin alpha 1. (914 aa)
ENSUAMP00000013482Uncharacterized protein. (91 aa)
ENSUAMP00000013919Uncharacterized protein. (497 aa)
GLMNGlomulin, FKBP associated protein. (437 aa)
NKX2-6NK2 homeobox 6. (268 aa)
APLNRApelin receptor; Belongs to the G-protein coupled receptor 1 family. (380 aa)
CBY1Chibby family member 1, beta catenin antagonist. (127 aa)
VWA5B1Von Willebrand factor A domain containing 5B1. (1209 aa)
RB1RB transcriptional corepressor 1. (870 aa)
RIPOR2PL48 domain-containing protein. (1063 aa)
IRX3Iroquois homeobox 3. (502 aa)
ENSUAMP00000015680Uncharacterized protein. (92 aa)
MAML1Mastermind like transcriptional coactivator 1. (933 aa)
ACADMAcyl-CoA dehydrogenase medium chain. (421 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
KELKell metallo-endopeptidase (Kell blood group). (716 aa)
ENSUAMP00000016162RH1 domain-containing protein. (260 aa)
FOXF1Forkhead box F1. (379 aa)
RAMP2Receptor activity modifying protein 2. (100 aa)
TMEM204Transmembrane protein 204. (226 aa)
VWA5AVon Willebrand factor A domain containing 5A. (804 aa)
FBXO40F-box protein 40. (708 aa)
LMNALamin A/C; Belongs to the intermediate filament family. (671 aa)
ENSUAMP00000017462Uncharacterized protein. (88 aa)
ENSUAMP00000017830Uncharacterized protein. (157 aa)
ACTA2Actin alpha 2, smooth muscle. (377 aa)
ENSUAMP00000018124Uncharacterized protein. (249 aa)
CHRNB1Cholinergic receptor nicotinic beta 1 subunit. (576 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
ACTA1Actin alpha 1, skeletal muscle. (377 aa)
MYOZ1Myozenin 1. (299 aa)
SYNPO2LSynaptopodin 2 like. (970 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2523 aa)
SRFSerum response factor. (507 aa)
DOCK5Dedicator of cytokinesis 5; Belongs to the DOCK family. (1750 aa)
ENSUAMP00000020340WH1 domain-containing protein. (244 aa)
KRASKRAS proto-oncogene, GTPase. (188 aa)
MYMXMyomixer, myoblast fusion factor. (84 aa)
ENSUAMP00000021241C2 domain-containing protein. (766 aa)
ENSUAMP00000021250Uncharacterized protein. (870 aa)
BCL9BCL9 transcription coactivator. (1426 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
ENSUAMP00000021972Uncharacterized protein. (778 aa)
SIX4SIX homeobox 4. (783 aa)
TNNT1Troponin T1, slow skeletal type. (256 aa)
LRRC10BLeucine rich repeat containing 10B. (292 aa)
ACTN2Actinin alpha 2. (894 aa)
SPAG9Sperm associated antigen 9. (1143 aa)
DUPD1Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (222 aa)
MEF2AMyocyte enhancer factor 2A. (466 aa)
ENSUAMP00000023559Uncharacterized protein. (132 aa)
LMOD3Leiomodin 3. (564 aa)
ENSUAMP00000023660Uncharacterized protein. (778 aa)
ACTG2Actin gamma 2, smooth muscle. (389 aa)
MYMKMyomaker, myoblast fusion factor. (221 aa)
KLHL41Kelch like family member 41. (606 aa)
RORARAR related orphan receptor A. (522 aa)
HDGFL2HDGF like 2. (671 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (344 aa)
MYPNMyopalladin. (1320 aa)
WFIKKN1WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1. (548 aa)
H3-3AHistone domain-containing protein. (142 aa)
TANC1Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1. (1827 aa)
ENSUAMP00000025619ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (153 aa)
LMOD1Leiomodin 1. (583 aa)
ENSUAMP00000026324Uncharacterized protein. (168 aa)
ENSUAMP00000026326SH3 domain-containing protein. (99 aa)
MECP2Methyl-CpG binding protein 2. (440 aa)
SOX9SRY-box transcription factor 9. (484 aa)
NPHS1NPHS1 adhesion molecule, nephrin. (1295 aa)
TNNT3Troponin T3, fast skeletal type. (260 aa)
R3HDM2Uncharacterized protein. (1084 aa)
STAC3SH3 and cysteine rich domain 3. (407 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (788 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
LMOD2Leiomodin 2. (553 aa)
ENSUAMP00000027802Uncharacterized protein; Belongs to the peptidase C2 family. (706 aa)
ENSUAMP00000028147Uncharacterized protein. (74 aa)
ENSUAMP00000028149Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (67 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (816 aa)
TMOD2Tropomodulin 2. (351 aa)
TMOD3Tropomodulin 3. (360 aa)
SORT1Sortilin. (829 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
FLNCFilamin C. (2681 aa)
DYSFDysferlin. (2066 aa)
ENSUAMP00000029003Uncharacterized protein. (105 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U. (825 aa)
PLEKHO1Pleckstrin homology domain containing O1. (405 aa)
CD9Tetraspanin. (226 aa)
SMARCD3SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (483 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
KLF5Kruppel like factor 5. (442 aa)
ENGEndoglin. (650 aa)
SEMA4CSemaphorin 4C; Belongs to the semaphorin family. (833 aa)
SPEGStriated muscle enriched protein kinase. (3235 aa)
MYL2Myosin light chain 2. (192 aa)
CD81Tetraspanin. (392 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
ENSUAMP00000032138Uncharacterized protein. (111 aa)
HOMER1Homer scaffold protein 1. (191 aa)
NPNTNephronectin. (462 aa)
ASB2Ankyrin repeat and SOCS box containing 2. (630 aa)
TSC1TSC complex subunit 1. (1168 aa)
R3HDM1R3H domain containing 1. (830 aa)
BIN3Bridging integrator 3. (253 aa)
ENSUAMP00000032677DHR-2 domain-containing protein; Belongs to the DOCK family. (412 aa)
ENSUAMP00000033199RHD domain-containing protein. (458 aa)
CXADRUncharacterized protein. (350 aa)
MYOM2Myomesin 2. (1445 aa)
ENSUAMP00000033631DHR-1 domain-containing protein; Belongs to the DOCK family. (759 aa)
PRKAR1AProtein kinase cAMP-dependent type I regulatory subunit alpha. (381 aa)
ENSUAMP00000033749Uncharacterized protein. (344 aa)
NEBNebulin. (7814 aa)
ENSUAMP00000033750Uncharacterized protein. (66 aa)
FHL2Four and a half LIM domains 2. (279 aa)
MRTFBSAP domain-containing protein. (974 aa)
NOTCH1Notch receptor 1. (2547 aa)
HEYLHes related family bHLH transcription factor with YRPW motif like. (328 aa)
ENSUAMP00000000384NAD_binding_6 domain-containing protein. (147 aa)
ENSUAMP00000000589Uncharacterized protein. (270 aa)
ENSUAMP00000000600Uncharacterized protein. (130 aa)
MYOZ2Myozenin 2. (264 aa)
TBX2T-box transcription factor 2. (697 aa)
VWA5B2Von Willebrand factor A domain containing 5B2. (1245 aa)
DYRK1BDual specificity tyrosine phosphorylation regulated kinase 1B. (614 aa)
ENSUAMP00000001962Uncharacterized protein. (141 aa)
MYOFMyoferlin. (2096 aa)
PROX1Prospero homeobox 1. (737 aa)
GREM1Gremlin 1, DAN family BMP antagonist. (240 aa)
TBX5T-box transcription factor 5. (517 aa)
CSRP2Cysteine and glycine rich protein 2. (272 aa)
ENSUAMP00000002781calpain_III domain-containing protein. (81 aa)
GALK1Galactokinase 1. (392 aa)
H3F3BHistone H3; Belongs to the histone H3 family. (136 aa)
ENSUAMP00000004725G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (253 aa)
ENSUAMP00000004728G_PROTEIN_RECEP_F1_2 domain-containing protein. (155 aa)
ACTC1Actin alpha cardiac muscle 1. (381 aa)
ENSUAMP00000004823SH3 domain-containing protein. (506 aa)
MRTFAMyocardin related transcription factor A. (926 aa)
ENSUAMP00000005311Uncharacterized protein. (1199 aa)
CSRP1Cysteine and glycine rich protein 1. (200 aa)
TNNT2Troponin T2, cardiac type. (215 aa)
ENSUAMP00000005541P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (437 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1872 aa)
TMOD1Tropomodulin 1. (359 aa)
MYORGMyogenesis regulating glycosidase (putative); Belongs to the glycosyl hydrolase 31 family. (714 aa)
C9orf24Chromosome 9 open reading frame 24. (261 aa)
ENSUAMP00000006515Uncharacterized protein. (190 aa)
CAPN3Calpain 3; Belongs to the peptidase C2 family. (750 aa)
ENSUAMP00000006638ZZ-type domain-containing protein. (342 aa)
CSRP3Cysteine and glycine rich protein 3. (194 aa)
ENSUAMP00000007554Uncharacterized protein. (354 aa)
ASF1AAnti-silencing function 1A histone chaperone. (204 aa)
SYPL2Synaptophysin like 2. (363 aa)
ADAMTS15ADAM metallopeptidase with thrombospondin type 1 motif 15. (950 aa)
IFRD2Interferon related developmental regulator 2. (441 aa)
ENSUAMP00000037129Uncharacterized protein. (66 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa)
PGM5Phosphoglucomutase 5; Belongs to the phosphohexose mutase family. (567 aa)
DOCK2Uncharacterized protein; Belongs to the DOCK family. (981 aa)
COMPCartilage oligomeric matrix protein. (756 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
LDB3LIM domain binding 3. (705 aa)
ENSUAMP00000036101Uncharacterized protein. (195 aa)
TMOD4Tropomodulin 4. (345 aa)
PRADC1Protease associated domain containing 1. (188 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
MYL10Myosin light chain 10. (215 aa)
ENSUAMP00000034792Uncharacterized protein. (279 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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