(13 nodes) Muscle cell fate commitment network (Ursus americanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSUAMP00000000600	Uncharacterized protein. (130 aa)
	PRADC1	Protease associated domain containing 1. (188 aa)
	MYL10	Myosin light chain 10. (215 aa)
	MYL2	Myosin light chain 2. (192 aa)
	MEF2C	Myocyte enhancer factor 2C. (483 aa)
	WNT8A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (344 aa)
	ENSUAMP00000017830	Uncharacterized protein. (157 aa)
	VWA5A	Von Willebrand factor A domain containing 5A. (804 aa)
	VWA5B1	Von Willebrand factor A domain containing 5B1. (1209 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
	TBX5	T-box transcription factor 5. (517 aa)
	VWA5B2	Von Willebrand factor A domain containing 5B2. (1245 aa)
	TBX2	T-box transcription factor 2. (697 aa)

Your Current Organism:

Ursus americanus

NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSUAMP00000000600	ENSUAMP00000017830	ENSUAMP00000000600	ENSUAMP00000017830	Uncharacterized protein.	Uncharacterized protein.	0.671
ENSUAMP00000017830	ENSUAMP00000000600	ENSUAMP00000017830	ENSUAMP00000000600	Uncharacterized protein.	Uncharacterized protein.	0.671
FGF10	TBX5	ENSUAMP00000008288	ENSUAMP00000002282	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	T-box transcription factor 5.	0.406
MEF2C	MYL2	ENSUAMP00000029640	ENSUAMP00000031073	Myocyte enhancer factor 2C.	Myosin light chain 2.	0.546
MEF2C	TBX5	ENSUAMP00000029640	ENSUAMP00000002282	Myocyte enhancer factor 2C.	T-box transcription factor 5.	0.743
MYL2	MEF2C	ENSUAMP00000031073	ENSUAMP00000029640	Myosin light chain 2.	Myocyte enhancer factor 2C.	0.546
MYL2	TBX5	ENSUAMP00000031073	ENSUAMP00000002282	Myosin light chain 2.	T-box transcription factor 5.	0.562
TBX5	FGF10	ENSUAMP00000002282	ENSUAMP00000008288	T-box transcription factor 5.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.406
TBX5	MEF2C	ENSUAMP00000002282	ENSUAMP00000029640	T-box transcription factor 5.	Myocyte enhancer factor 2C.	0.743
TBX5	MYL2	ENSUAMP00000002282	ENSUAMP00000031073	T-box transcription factor 5.	Myosin light chain 2.	0.562