STRINGSTRING
PROX1 PROX1 ENSUAMP00000002472 ENSUAMP00000002472 ROBO4 ROBO4 FSTL1 FSTL1 ENSUAMP00000004725 ENSUAMP00000004725 ENSUAMP00000004728 ENSUAMP00000004728 F2RL1 F2RL1 MYD88 MYD88 MARVELD2 MARVELD2 COL15A1 COL15A1 ENSUAMP00000014407 ENSUAMP00000014407 HPSE HPSE CCM2 CCM2 HAPLN2 HAPLN2 ACVRL1 ACVRL1 RAP1A RAP1A PTPRS PTPRS SMAD4 SMAD4 TJP1 TJP1 UBIAD1 UBIAD1 MSN MSN PLOD3 PLOD3 MYADM MYADM ENSUAMP00000021285 ENSUAMP00000021285 KDR KDR ENSUAMP00000025912 ENSUAMP00000025912 TJP3 TJP3 HOXB5 HOXB5 ENSUAMP00000028668 ENSUAMP00000028668 DLL1 DLL1 EZR EZR TMEM100 TMEM100 FASN FASN F11R F11R NOTCH1 NOTCH1 PECAM1 PECAM1 ENSUAMP00000035608 ENSUAMP00000035608 ENSUAMP00000035622 ENSUAMP00000035622 ENSUAMP00000035960 ENSUAMP00000035960 RAPGEF2 RAPGEF2 SOX17 SOX17 PDE2A PDE2A BMPR2 BMPR2 TIE1 TIE1 FZD2 FZD2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PROX1Prospero homeobox 1. (737 aa)
ENSUAMP00000002472Uncharacterized protein. (101 aa)
ROBO4Roundabout guidance receptor 4. (927 aa)
FSTL1Follistatin like 1. (307 aa)
ENSUAMP00000004725G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (253 aa)
ENSUAMP00000004728G_PROTEIN_RECEP_F1_2 domain-containing protein. (155 aa)
F2RL1F2R like trypsin receptor 1. (397 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa)
MARVELD2MARVEL domain containing 2. (559 aa)
COL15A1Collagen type XV alpha 1 chain. (1372 aa)
ENSUAMP00000014407annotation not available (101 aa)
HPSEHeparanase. (504 aa)
CCM2CCM2 scaffold protein. (453 aa)
HAPLN2Hyaluronan and proteoglycan link protein 2. (340 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (518 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
PTPRSProtein tyrosine phosphatase receptor type S. (1910 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (1744 aa)
UBIAD1UbiA prenyltransferase domain containing 1. (337 aa)
MSNMoesin. (577 aa)
PLOD3Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3. (792 aa)
MYADMMyeloid associated differentiation marker. (322 aa)
ENSUAMP00000021285Uncharacterized protein; Belongs to the MAGUK family. (1144 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1282 aa)
ENSUAMP00000025912Uncharacterized protein. (134 aa)
TJP3Tight junction protein 3; Belongs to the MAGUK family. (884 aa)
HOXB5Homeobox B5. (269 aa)
ENSUAMP00000028668Uncharacterized protein. (138 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (757 aa)
EZREzrin. (586 aa)
TMEM100Transmembrane protein 100. (134 aa)
FASNFatty acid synthase. (2519 aa)
F11RF11 receptor. (298 aa)
NOTCH1Notch receptor 1. (2547 aa)
PECAM1Platelet and endothelial cell adhesion molecule 1. (707 aa)
ENSUAMP00000035608Uncharacterized protein. (85 aa)
ENSUAMP00000035622Uncharacterized protein. (662 aa)
ENSUAMP00000035960Uncharacterized protein. (707 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1516 aa)
SOX17SRY-box transcription factor 17. (406 aa)
PDE2APhosphodiesterase. (975 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (857 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1069 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (563 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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