STRINGSTRING
ENSUAMP00000000756 ENSUAMP00000000756 LTF LTF FFAR4 FFAR4 SCUBE2 SCUBE2 ENSUAMP00000002966 ENSUAMP00000002966 DDR2 DDR2 ACVR2B ACVR2B TP63 TP63 ATRAID ATRAID PPP3CA PPP3CA PRKD1 PRKD1 FBXO5 FBXO5 ENSUAMP00000010127 ENSUAMP00000010127 ZHX3 ZHX3 ENSUAMP00000013482 ENSUAMP00000013482 ACVR2A ACVR2A WWTR1 WWTR1 FERMT2 FERMT2 SCUBE3 SCUBE3 TENT5A TENT5A CTNNBIP1 CTNNBIP1 BMP2 BMP2 SMAD5 SMAD5 CTHRC1 CTHRC1 CCN1 CCN1 SUCO SUCO CCN4 CCN4 GDPD2 GDPD2 ENSUAMP00000025354 ENSUAMP00000025354 LRP5 LRP5 ENSUAMP00000025477 ENSUAMP00000025477 CEBPB CEBPB ENSUAMP00000027842 ENSUAMP00000027842 ENSUAMP00000027843 ENSUAMP00000027843 BMP4 BMP4 ENSUAMP00000029322 ENSUAMP00000029322 MEF2C MEF2C IL6ST IL6ST PDLIM7 PDLIM7 TMEM119 TMEM119 NPNT NPNT GLI3 GLI3 BMPR1B BMPR1B ILK ILK JAG1 JAG1 WNT10B WNT10B BMPR1A BMPR1A BMPR2 BMPR2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSUAMP00000000756MH1 domain-containing protein. (170 aa)
LTFLactotransferrin; Belongs to the transferrin family. (706 aa)
FFAR4Free fatty acid receptor 4. (372 aa)
SCUBE2Signal peptide, CUB domain and EGF like domain containing 2. (1071 aa)
ENSUAMP00000002966Uncharacterized protein. (375 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (873 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (527 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
ATRAIDAll-trans retinoic acid induced differentiation factor. (229 aa)
PPP3CASerine/threonine-protein phosphatase. (317 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (848 aa)
FBXO5F-box protein 5. (448 aa)
ENSUAMP00000010127Kindlin_2_N domain-containing protein. (70 aa)
ZHX3Zinc fingers and homeoboxes 3. (957 aa)
ENSUAMP00000013482Uncharacterized protein. (91 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (510 aa)
WWTR1WW domain containing transcription regulator 1. (400 aa)
FERMT2Fermitin family member 2. (567 aa)
SCUBE3Signal peptide, CUB domain and EGF like domain containing 3. (977 aa)
TENT5ATerminal nucleotidyltransferase 5A. (487 aa)
CTNNBIP1Catenin beta interacting protein 1. (70 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
CTHRC1Collagen triple helix repeat containing 1. (277 aa)
CCN1Cellular communication network factor 1. (382 aa)
SUCOSUN domain containing ossification factor. (1242 aa)
CCN4Cellular communication network factor 4. (361 aa)
GDPD2Glycerophosphodiester phosphodiesterase domain containing 2. (539 aa)
ENSUAMP00000025354HMG box domain-containing protein. (302 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1606 aa)
ENSUAMP00000025477Uncharacterized protein. (185 aa)
CEBPBCCAAT/enhancer-binding protein. (346 aa)
ENSUAMP00000027842Uncharacterized protein. (99 aa)
ENSUAMP00000027843Uncharacterized protein. (119 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
ENSUAMP00000029322Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (102 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
IL6STInterleukin 6 signal transducer. (918 aa)
PDLIM7PDZ and LIM domain 7. (458 aa)
TMEM119Transmembrane protein 119. (288 aa)
NPNTNephronectin. (462 aa)
GLI3GLI family zinc finger 3. (1413 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (502 aa)
ILKIntegrin linked kinase. (503 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1226 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (857 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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