STRINGSTRING
ENSUAMP00000024998 ENSUAMP00000024998 NME1 NME1 ENSUAMP00000004415 ENSUAMP00000004415 AK3 AK3 NME9 NME9 NME2 NME2 ENSUAMP00000006237 ENSUAMP00000006237 RAN RAN IMPDH1 IMPDH1 MFN1 MFN1 AK3-2 AK3-2 AK3-3 AK3-3 ENSUAMP00000014498 ENSUAMP00000014498 ENSUAMP00000014503 ENSUAMP00000014503 ENSUAMP00000014757 ENSUAMP00000014757 ENSUAMP00000015279 ENSUAMP00000015279 LRRK2 LRRK2 NME3 NME3 RAB23 RAB23 NME4 NME4 ENSUAMP00000022722 ENSUAMP00000022722 IMPDH2 IMPDH2 ENSUAMP00000035827 ENSUAMP00000035827 OPA1 OPA1 ENSUAMP00000034767 ENSUAMP00000034767 ENSUAMP00000032042 ENSUAMP00000032042 ENTPD7 ENTPD7 NME6 NME6 ENSUAMP00000030481 ENSUAMP00000030481 ENSUAMP00000028888 ENSUAMP00000028888 EFL1 EFL1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSUAMP00000024998NDK domain-containing protein. (144 aa)
NME1Nucleoside diphosphate kinase. (152 aa)
ENSUAMP00000004415AIG1-type G domain-containing protein. (326 aa)
AK3GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (235 aa)
NME9NME/NM23 family member 9. (268 aa)
NME2Nucleoside diphosphate kinase. (159 aa)
ENSUAMP00000006237AIG1-type G domain-containing protein. (328 aa)
RANGTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (279 aa)
IMPDH1Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (609 aa)
MFN1Mitofusin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (744 aa)
AK3-2GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (283 aa)
AK3-3GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (235 aa)
ENSUAMP00000014498Uncharacterized protein. (73 aa)
ENSUAMP00000014503Tr-type G domain-containing protein. (477 aa)
ENSUAMP00000014757AIG1-type G domain-containing protein. (325 aa)
ENSUAMP00000015279NDK domain-containing protein; Belongs to the NDK family. (181 aa)
LRRK2Leucine rich repeat kinase 2. (1967 aa)
NME3Nucleoside diphosphate kinase. (169 aa)
RAB23RAB23, member RAS oncogene family. (237 aa)
NME4Nucleoside diphosphate kinase. (187 aa)
ENSUAMP00000022722Uncharacterized protein. (223 aa)
IMPDH2Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (514 aa)
ENSUAMP00000035827Uncharacterized protein. (175 aa)
OPA1OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (1015 aa)
ENSUAMP00000034767Uncharacterized protein; Belongs to the adenylate kinase family. (120 aa)
ENSUAMP00000032042Uncharacterized protein. (94 aa)
ENTPD7Ectonucleoside triphosphate diphosphohydrolase 7; Belongs to the GDA1/CD39 NTPase family. (485 aa)
NME6Nucleoside diphosphate kinase. (186 aa)
ENSUAMP00000030481AIG1-type G domain-containing protein. (206 aa)
ENSUAMP00000028888NDK domain-containing protein; Belongs to the NDK family. (89 aa)
EFL1Elongation factor like GTPase 1. (1128 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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