STRINGSTRING
F2RL1 F2RL1 ZMYND11 ZMYND11 DUSP10 DUSP10 ENSUAMP00000025261 ENSUAMP00000025261 HDAC3 HDAC3 TAOK3 TAOK3 ITCH ITCH DACT1 DACT1 CYLD CYLD ENSUAMP00000035159 ENSUAMP00000035159 PAFAH1B1 PAFAH1B1 ENSUAMP00000016331 ENSUAMP00000016331 ENSUAMP00000018641 ENSUAMP00000018641 KLHL31 KLHL31 ENSUAMP00000022260 ENSUAMP00000022260 ENSUAMP00000023088 ENSUAMP00000023088 FKTN FKTN NCOR1 NCOR1 MECOM MECOM PRMT1 PRMT1 DUSP16 DUSP16 SFRP1 SFRP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
F2RL1F2R like trypsin receptor 1. (397 aa)
ZMYND11Zinc finger MYND-type containing 11. (529 aa)
DUSP10Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa)
ENSUAMP00000025261GPS2_interact domain-containing protein. (204 aa)
HDAC3Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
TAOK3TAO kinase 3. (898 aa)
ITCHE3 ubiquitin-protein ligase. (740 aa)
DACT1Dishevelled binding antagonist of beta catenin 1. (827 aa)
CYLDCYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (953 aa)
ENSUAMP00000035159Uncharacterized protein. (321 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)
ENSUAMP00000016331Ubiquitin-like domain-containing protein. (153 aa)
ENSUAMP00000018641Uncharacterized protein. (53 aa)
KLHL31Kelch like family member 31. (634 aa)
ENSUAMP00000022260Uncharacterized protein. (154 aa)
ENSUAMP00000023088Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (208 aa)
FKTNFukutin. (329 aa)
NCOR1Nuclear receptor corepressor 1. (2267 aa)
MECOMMDS1 and EVI1 complex locus. (1120 aa)
PRMT1Protein arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (353 aa)
DUSP16Dual specificity phosphatase 16. (663 aa)
SFRP1Secreted frizzled related protein 1. (337 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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