STRINGSTRING
ACOT7 ACOT7 ENSUAMP00000004668 ENSUAMP00000004668 ENSUAMP00000004665 ENSUAMP00000004665 ENSUAMP00000003787 ENSUAMP00000003787 ENSUAMP00000003272 ENSUAMP00000003272 PSPH PSPH UROS UROS LGSN LGSN FADS3 FADS3 ENSUAMP00000002211 ENSUAMP00000002211 ACSBG2 ACSBG2 ENSUAMP00000001197 ENSUAMP00000001197 ENSUAMP00000001167 ENSUAMP00000001167 LIPG LIPG ALDH8A1 ALDH8A1 ELOVL6 ELOVL6 SDSL SDSL ENSUAMP00000000314 ENSUAMP00000000314 ENSUAMP00000000227 ENSUAMP00000000227 ENSUAMP00000036260 ENSUAMP00000036260 ILVBL ILVBL ELOVL3 ELOVL3 ALDH1A3 ALDH1A3 SDS SDS ENSUAMP00000037561 ENSUAMP00000037561 HTD2 HTD2 PRKAG1 PRKAG1 ENSUAMP00000035580 ENSUAMP00000035580 HSD17B8 HSD17B8 ENSUAMP00000034957 ENSUAMP00000034957 ENSUAMP00000034435 ENSUAMP00000034435 ENSUAMP00000034433 ENSUAMP00000034433 ENSUAMP00000034431 ENSUAMP00000034431 PRXL2B PRXL2B RGN RGN ENSUAMP00000033138 ENSUAMP00000033138 SRR SRR CD74 CD74 GLUL GLUL PHGDH PHGDH NANP NANP FASN FASN BHMT BHMT BHMT2 BHMT2 GATM GATM SYK SYK DEGS1 DEGS1 SLC27A2 SLC27A2 ACSF3 ACSF3 GOT1 GOT1 HSD17B10 HSD17B10 DAGLB DAGLB OTC OTC GOT1L1 GOT1L1 EDN1 EDN1 KDM1A KDM1A MGST2 MGST2 ENSUAMP00000029394 ENSUAMP00000029394 HNF1A HNF1A AGXT2 AGXT2 GATD1 GATD1 TECRL TECRL PRKAB2 PRKAB2 ABCD3 ABCD3 GLS2 GLS2 PTGES3 PTGES3 ALDH18A1 ALDH18A1 ENSUAMP00000027887 ENSUAMP00000027887 MGLL MGLL MTHFD1 MTHFD1 PRKAG3 PRKAG3 CYP27A1 CYP27A1 ENSUAMP00000027762 ENSUAMP00000027762 ALOX12 ALOX12 ENSUAMP00000027384 ENSUAMP00000027384 SHMT2 SHMT2 PLOD2 PLOD2 PTGIS PTGIS ALOX5AP ALOX5AP ENSUAMP00000025837 ENSUAMP00000025837 PLA2G4F PLA2G4F PNPLA8 PNPLA8 ALOX5 ALOX5 CBR4 CBR4 HACD3 HACD3 ELOVL5 ELOVL5 THNSL2 THNSL2 PLA2G1B PLA2G1B DHRS9 DHRS9 KMO KMO PTGES PTGES ENSUAMP00000024580 ENSUAMP00000024580 MTHFR MTHFR LDHA LDHA LDHAL6B LDHAL6B AGXT AGXT FADS1 FADS1 SCD SCD PLP1 PLP1 ENSUAMP00000023441 ENSUAMP00000023441 MTR MTR ENSUAMP00000023340 ENSUAMP00000023340 PTGS1 PTGS1 ADI1 ADI1 LPL LPL ACSBG1 ACSBG1 CYP8B1 CYP8B1 ENSUAMP00000022373 ENSUAMP00000022373 TECR TECR KYNU KYNU PYCR1 PYCR1 NDUFAB1 NDUFAB1 ACSM1 ACSM1 ENSUAMP00000021498 ENSUAMP00000021498 ACSM5 ACSM5 ELOVL2 ELOVL2 PAH PAH ENSUAMP00000020850 ENSUAMP00000020850 AASS AASS PLOD3 PLOD3 AKR1D1 AKR1D1 DECR2 DECR2 MRI1 MRI1 PTGS2 PTGS2 CYP39A1 CYP39A1 MTHFD1L MTHFD1L GAMT GAMT ENSUAMP00000018500 ENSUAMP00000018500 WDR37 WDR37 FA2H FA2H ENSUAMP00000017426 ENSUAMP00000017426 ENSUAMP00000017381 ENSUAMP00000017381 ENSUAMP00000017349 ENSUAMP00000017349 ENSUAMP00000017347 ENSUAMP00000017347 MGST3 MGST3 ABHD3 ABHD3 ENSUAMP00000016504 ENSUAMP00000016504 TBXAS1 TBXAS1 ENSUAMP00000016286 ENSUAMP00000016286 PYCR3 PYCR3 ENSUAMP00000015938 ENSUAMP00000015938 PARK7 PARK7 ENSUAMP00000015723 ENSUAMP00000015723 ALOX15 ALOX15 ENSUAMP00000014746 ENSUAMP00000014746 TMED8 TMED8 PLA2G5 PLA2G5 NOXRED1 NOXRED1 ENSUAMP00000014177 ENSUAMP00000014177 ENOPH1 ENOPH1 ASNS ASNS IDO1 IDO1 GGT5 GGT5 ENSUAMP00000013400 ENSUAMP00000013400 UPB1 UPB1 SHMT1 SHMT1 ENSUAMP00000013328 ENSUAMP00000013328 ACACB ACACB OXSM OXSM BCAT2 BCAT2 ARMC7 ARMC7 FADS6 FADS6 C10orf62 C10orf62 HOGA1 HOGA1 MTRR MTRR ENSUAMP00000012599 ENSUAMP00000012599 ENSUAMP00000012486 ENSUAMP00000012486 PTGES2 PTGES2 PLA2G4A PLA2G4A PSAT1 PSAT1 ENSUAMP00000012071 ENSUAMP00000012071 SEPHS1 SEPHS1 HACD4 HACD4 ENSUAMP00000011307 ENSUAMP00000011307 ENSUAMP00000011289 ENSUAMP00000011289 THNSL1 THNSL1 LIPH LIPH HSD17B12 HSD17B12 UGDH UGDH AASDHPPT AASDHPPT ENSUAMP00000001063 ENSUAMP00000001063 ENSUAMP00000001000 ENSUAMP00000001000 ENSUAMP00000000911 ENSUAMP00000000911 ELOVL1 ELOVL1 LIAS LIAS MTAP MTAP ENSUAMP00000000499 ENSUAMP00000000499 ENSUAMP00000010243 ENSUAMP00000010243 CTH CTH PLA2G10 PLA2G10 AKR1A1 AKR1A1 LTA4H LTA4H APIP APIP MCAT MCAT RDH10 RDH10 ELOVL4 ELOVL4 ENSUAMP00000008512 ENSUAMP00000008512 CAD CAD ENSUAMP00000008067 ENSUAMP00000008067 ABHD1 ABHD1 LIPC LIPC HAAO HAAO NAGS NAGS CYP7B1 CYP7B1 OAT OAT MECR MECR MLYCD MLYCD CARNS1 CARNS1 ELOVL7 ELOVL7 ENSUAMP00000006430 ENSUAMP00000006430 ENSUAMP00000006241 ENSUAMP00000006241 HSDL1 HSDL1 ALOX15B ALOX15B ALOX12B ALOX12B ALOXE3 ALOXE3 ENSUAMP00000005719 ENSUAMP00000005719 GAD1 GAD1 ENSUAMP00000005111 ENSUAMP00000005111 ENSUAMP00000005051 ENSUAMP00000005051 SEPHS2 SEPHS2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACOT7Acyl-CoA thioesterase 7. (357 aa)
ENSUAMP00000004668Uncharacterized protein. (95 aa)
ENSUAMP00000004665AMP-binding domain-containing protein. (629 aa)
ENSUAMP00000003787Uncharacterized protein. (209 aa)
ENSUAMP00000003272SHMT domain-containing protein. (59 aa)
PSPHPhosphoserine phosphatase. (225 aa)
UROSUroporphyrinogen III synthase. (264 aa)
LGSNLengsin, lens protein with glutamine synthetase domain; Belongs to the glutamine synthetase family. (509 aa)
FADS3Fatty acid desaturase 3. (443 aa)
ENSUAMP00000002211FA_desaturase domain-containing protein. (243 aa)
ACSBG2Acyl-CoA synthetase bubblegum family member 2. (660 aa)
ENSUAMP00000001197Uncharacterized protein. (228 aa)
ENSUAMP00000001167AMP-binding domain-containing protein. (493 aa)
LIPGLipase G, endothelial type. (494 aa)
ALDH8A1Aldehyde dehydrogenase 8 family member A1; Belongs to the aldehyde dehydrogenase family. (487 aa)
ELOVL6Elongation of very long chain fatty acids protein. (181 aa)
SDSLSerine dehydratase like. (329 aa)
ENSUAMP00000000314Amino acid transporter. (115 aa)
ENSUAMP00000000227Uncharacterized protein. (123 aa)
ENSUAMP00000036260Uncharacterized protein. (1033 aa)
ILVBLIlvB acetolactate synthase like; Belongs to the TPP enzyme family. (632 aa)
ELOVL3Elongation of very long chain fatty acids protein 3; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precurs [...] (270 aa)
ALDH1A3Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family. (512 aa)
SDSSerine dehydratase. (328 aa)
ENSUAMP00000037561Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (374 aa)
HTD2Hydroxyacyl-thioester dehydratase type 2. (168 aa)
PRKAG1Protein kinase AMP-activated non-catalytic subunit gamma 1. (330 aa)
ENSUAMP00000035580Lipase domain-containing protein. (153 aa)
HSD17B8Hydroxysteroid 17-beta dehydrogenase 8. (259 aa)
ENSUAMP00000034957Uncharacterized protein. (149 aa)
ENSUAMP00000034435EF-hand_14 domain-containing protein. (259 aa)
ENSUAMP00000034433Uncharacterized protein. (103 aa)
ENSUAMP00000034431ANK_REP_REGION domain-containing protein. (93 aa)
PRXL2BPeroxiredoxin like 2B. (218 aa)
RGNRegucalcin. (299 aa)
ENSUAMP00000033138Uncharacterized protein. (153 aa)
SRRSerine racemase. (339 aa)
CD74CD74 molecule. (279 aa)
GLULGlutamine synthetase. (484 aa)
PHGDHD-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (533 aa)
NANPN-acetylneuraminic acid phosphatase. (248 aa)
FASNFatty acid synthase. (2519 aa)
BHMTBetaine--homocysteine S-methyltransferase; Involved in the regulation of homocysteine metabolism. (407 aa)
BHMT2Betaine--homocysteine S-methyltransferase 2; Involved in the regulation of homocysteine metabolism. (363 aa)
GATMGlycine amidinotransferase. (423 aa)
SYKSpleen associated tyrosine kinase. (638 aa)
DEGS1Delta 4-desaturase, sphingolipid 1. (323 aa)
SLC27A2Solute carrier family 27 member 2. (385 aa)
ACSF3Acyl-CoA synthetase family member 3. (537 aa)
GOT1Aspartate aminotransferase. (413 aa)
HSD17B10Hydroxysteroid 17-beta dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (261 aa)
DAGLBDiacylglycerol lipase beta. (671 aa)
OTCOrnithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (354 aa)
GOT1L1Glutamic-oxaloacetic transaminase 1 like 1. (406 aa)
EDN1Endothelin 1. (202 aa)
KDM1ALysine demethylase 1A. (734 aa)
MGST2Microsomal glutathione S-transferase 2. (146 aa)
ENSUAMP00000029394Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (267 aa)
HNF1AHNF1 homeobox A. (631 aa)
AGXT2Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (513 aa)
GATD1Glutamine amidotransferase like class 1 domain containing 1. (220 aa)
TECRLTrans-2,3-enoyl-CoA reductase like. (341 aa)
PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (286 aa)
ABCD3ATP binding cassette subfamily D member 3. (604 aa)
GLS2Glutaminase 2. (602 aa)
PTGES3Prostaglandin E synthase 3. (180 aa)
ALDH18A1Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. (795 aa)
ENSUAMP00000027887Uncharacterized protein. (303 aa)
MGLLMonoglyceride lipase. (304 aa)
MTHFD1Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1. (992 aa)
PRKAG3Protein kinase AMP-activated non-catalytic subunit gamma 3. (491 aa)
CYP27A1Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family. (441 aa)
ENSUAMP00000027762Uncharacterized protein. (188 aa)
ALOX12Arachidonate 12-lipoxygenase, 12S type. (666 aa)
ENSUAMP00000027384Beta_elim_lyase domain-containing protein. (401 aa)
SHMT2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (504 aa)
PLOD2Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2. (728 aa)
PTGISProstaglandin I2 synthase; Belongs to the cytochrome P450 family. (499 aa)
ALOX5APArachidonate 5-lipoxygenase activating protein. (198 aa)
ENSUAMP00000025837Ceramidse_alk_C domain-containing protein. (150 aa)
PLA2G4FPhospholipase A2. (837 aa)
PNPLA8Patatin like phospholipase domain containing 8. (780 aa)
ALOX5Arachidonate 5-lipoxygenase. (674 aa)
CBR4Carbonyl reductase 4. (237 aa)
HACD3Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (337 aa)
ELOVL5Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involv [...] (299 aa)
THNSL2Threonine synthase like 2. (435 aa)
PLA2G1BPhospholipase A(2). (119 aa)
DHRS9Dehydrogenase/reductase 9; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (319 aa)
KMOKynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. (477 aa)
PTGESProstaglandin E synthase. (153 aa)
ENSUAMP00000024580Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (241 aa)
MTHFRMethylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (654 aa)
LDHAL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (332 aa)
LDHAL6BL-lactate dehydrogenase. (236 aa)
AGXTSerine--pyruvate aminotransferase. (414 aa)
FADS1Fatty acid desaturase 1. (466 aa)
SCDStearoyl-CoA desaturase; Belongs to the fatty acid desaturase type 1 family. (359 aa)
PLP1Proteolipid protein 1. (277 aa)
ENSUAMP00000023441DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (187 aa)
MTRMethionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1178 aa)
ENSUAMP00000023340DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (187 aa)
PTGS1Prostaglandin-endoperoxide synthase 1. (618 aa)
ADI11,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Belongs to the acireductone dioxygenase (ARD) family. (179 aa)
LPLLipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (476 aa)
ACSBG1Acyl-CoA synthetase bubblegum family member 1. (703 aa)
CYP8B1Cytochrome P450 family 8 subfamily B member 1; Belongs to the cytochrome P450 family. (501 aa)
ENSUAMP00000022373Uncharacterized protein. (178 aa)
TECRTrans-2,3-enoyl-CoA reductase. (410 aa)
KYNUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. Belongs to the kynureninase family. (422 aa)
PYCR1Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (320 aa)
NDUFAB1Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (154 aa)
ACSM1Acyl-CoA synthetase medium chain family member 1. (577 aa)
ENSUAMP00000021498Uncharacterized protein. (452 aa)
ACSM5Acyl-CoA synthetase medium chain family member 5. (588 aa)
ELOVL2Elongation of very long chain fatty acids protein 2; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production [...] (279 aa)
PAHPhenylalanine hydroxylase. (409 aa)
ENSUAMP00000020850Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (176 aa)
AASSAminoadipate-semialdehyde synthase. (906 aa)
PLOD3Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3. (792 aa)
AKR1D1Aldo-keto reductase family 1 member D1. (323 aa)
DECR22,4-dienoyl-CoA reductase 2. (290 aa)
MRI1Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (384 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
CYP39A1Cytochrome P450 family 39 subfamily A member 1; Belongs to the cytochrome P450 family. (469 aa)
MTHFD1LMethylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. (961 aa)
GAMTGuanidinoacetate N-methyltransferase; Converts guanidinoacetate to creatine, using S- adenosylmethionine as the methyl donor. Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family. (236 aa)
ENSUAMP00000018500Fer4_20 domain-containing protein. (166 aa)
WDR37WD repeat domain 37. (496 aa)
FA2HFatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (372 aa)
ENSUAMP00000017426Cytochrome b5 heme-binding domain-containing protein. (478 aa)
ENSUAMP00000017381Uncharacterized protein. (128 aa)
ENSUAMP00000017349Uncharacterized protein. (125 aa)
ENSUAMP00000017347Uncharacterized protein. (64 aa)
MGST3Microsomal glutathione S-transferase 3. (152 aa)
ABHD3Abhydrolase domain containing 3. (369 aa)
ENSUAMP00000016504BRCT domain-containing protein. (101 aa)
TBXAS1Thromboxane A synthase 1. (441 aa)
ENSUAMP00000016286Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (249 aa)
PYCR3Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (276 aa)
ENSUAMP00000015938Uncharacterized protein; Belongs to the fatty acid desaturase type 1 family. (134 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
ENSUAMP00000015723Uncharacterized protein. (179 aa)
ALOX15Arachidonate 15-lipoxygenase. (672 aa)
ENSUAMP00000014746ALO domain-containing protein. (372 aa)
TMED8Transmembrane p24 trafficking protein family member 8. (332 aa)
PLA2G5Phospholipase A(2). (137 aa)
NOXRED1NADP dependent oxidoreductase domain containing 1. (329 aa)
ENSUAMP00000014177Glutamine amidotransferase type-2 domain-containing protein. (644 aa)
ENOPH1Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (261 aa)
ASNSAsparagine synthetase [glutamine-hydrolyzing]. (561 aa)
IDO1Indoleamine 2,3-dioxygenase 1. (386 aa)
GGT5Gamma-glutamyltransferase 5. (570 aa)
ENSUAMP00000013400Uncharacterized protein. (569 aa)
UPB1Beta-ureidopropionase 1. (384 aa)
SHMT1Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (484 aa)
ENSUAMP00000013328Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (237 aa)
ACACBAcetyl-CoA carboxylase beta. (2045 aa)
OXSM3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (460 aa)
BCAT2Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (463 aa)
ARMC7Armadillo repeat containing 7. (198 aa)
FADS6Fatty acid desaturase 6. (340 aa)
C10orf62Chromosome 10 open reading frame 62. (229 aa)
HOGA14-hydroxy-2-oxoglutarate aldolase 1; Belongs to the DapA family. (327 aa)
MTRR5-methyltetrahydrofolate-homocysteine methyltransferase reductase. (723 aa)
ENSUAMP00000012599Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (573 aa)
ENSUAMP00000012486Uncharacterized protein. (314 aa)
PTGES2Prostaglandin E synthase 2; Belongs to the GST superfamily. (372 aa)
PLA2G4APhospholipase A2. (756 aa)
PSAT1Phosphoserine aminotransferase. (334 aa)
ENSUAMP00000012071GST N-terminal domain-containing protein. (193 aa)
SEPHS1Selenophosphate synthetase 1. (392 aa)
HACD4Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (229 aa)
ENSUAMP00000011307Uncharacterized protein. (1315 aa)
ENSUAMP00000011289Uncharacterized protein. (495 aa)
THNSL1Threonine synthase like 1. (743 aa)
LIPHLipase H. (396 aa)
HSD17B12Hydroxysteroid 17-beta dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (227 aa)
UGDHUDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (494 aa)
AASDHPPTAminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase. (309 aa)
ENSUAMP00000001063Elongation of very long chain fatty acids protein. (96 aa)
ENSUAMP00000001000Aldedh domain-containing protein. (224 aa)
ENSUAMP00000000911Uncharacterized protein. (111 aa)
ELOVL1Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] (291 aa)
LIASLipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (373 aa)
MTAPS-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (255 aa)
ENSUAMP00000000499Uncharacterized protein. (435 aa)
ENSUAMP00000010243Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (318 aa)
CTHCystathionine gamma-lyase. (409 aa)
PLA2G10Phospholipase A(2). (157 aa)
AKR1A1Aldo-keto reductase family 1 member A1. (333 aa)
LTA4HLeukotriene A(4) hydrolase; Belongs to the peptidase M1 family. (611 aa)
APIPAPAF1 interacting protein. (199 aa)
MCATMalonyl-CoA-acyl carrier protein transacylase. (379 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
ELOVL4Elongation of very long chain fatty acids protein 4; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane [...] (314 aa)
ENSUAMP00000008512Biotin carboxylation domain-containing protein. (206 aa)
CADCarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. (2218 aa)
ENSUAMP00000008067BAAT_C domain-containing protein. (197 aa)
ABHD1Abhydrolase domain containing 1. (374 aa)
LIPCLipase C, hepatic type. (498 aa)
HAAO3-hydroxyanthranilate 3,4-dioxygenase. (264 aa)
NAGSN-acetylglutamate synthase. (523 aa)
CYP7B1Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. (485 aa)
OATOrnithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (399 aa)
MECRMitochondrial trans-2-enoyl-CoA reductase. (374 aa)
MLYCDMalonyl-CoA decarboxylase. (500 aa)
CARNS1Carnosine synthase 1. (859 aa)
ELOVL7Elongation of very long chain fatty acids protein 7; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0 [...] (281 aa)
ENSUAMP00000006430Uncharacterized protein; Belongs to the GST superfamily. (226 aa)
ENSUAMP00000006241GST N-terminal domain-containing protein. (60 aa)
HSDL1Hydroxysteroid dehydrogenase like 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (306 aa)
ALOX15BArachidonate 15-lipoxygenase type B. (687 aa)
ALOX12BArachidonate 12-lipoxygenase, 12R type. (699 aa)
ALOXE3Arachidonate lipoxygenase 3. (711 aa)
ENSUAMP00000005719Ldh_1_N domain-containing protein. (127 aa)
GAD1Glutamate decarboxylase 1. (594 aa)
ENSUAMP00000005111Aldedh domain-containing protein. (208 aa)
ENSUAMP00000005051Uncharacterized protein. (58 aa)
SEPHS2Selenophosphate synthetase 2. (347 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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