STRINGSTRING
ENSUAMP00000031091 ENSUAMP00000031091 LBX1 LBX1 NKX2-1 NKX2-1 EHMT2 EHMT2 GLI3 GLI3 ISL2 ISL2 NKX2-2 NKX2-2 FEZF2 FEZF2 HOXD10 HOXD10 NOTCH1 NOTCH1 WNT1 WNT1 ZNF521 ZNF521 EPOP EPOP OLIG2 OLIG2 MYT1L MYT1L ATOH7 ATOH7 OLIG3 OLIG3 DLL4 DLL4 ENSUAMP00000020431 ENSUAMP00000020431 EYA1 EYA1 ATOH1 ATOH1 GSX2 GSX2 SMAD4 SMAD4 IHH IHH ENSUAMP00000027843 ENSUAMP00000027843 ENSUAMP00000027842 ENSUAMP00000027842 DMRTA2 DMRTA2 FEV FEV NKX6-2 NKX6-2 SOX9 SOX9 TLX3 TLX3 ENSUAMP00000000316 ENSUAMP00000000316 ENSUAMP00000000397 ENSUAMP00000000397 HOXC10 HOXC10 ENSUAMP00000001477 ENSUAMP00000001477 PROX1 PROX1 ISL1 ISL1 DBX1 DBX1 ENSUAMP00000009098 ENSUAMP00000009098 DLX1 DLX1 DLX2 DLX2 ENSUAMP00000010093 ENSUAMP00000010093 ASCL1 ASCL1 FOXN4 FOXN4 FOXA1 FOXA1 JAG2 JAG2 DMRT3 DMRT3 TGFBR1 TGFBR1 LHX3 LHX3 TBR1 TBR1 BMP4 BMP4 DLL1 DLL1 GSX1 GSX1 ENSUAMP00000030304 ENSUAMP00000030304
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSUAMP00000031091Uncharacterized protein. (151 aa)
LBX1Ladybird homeobox 1. (281 aa)
NKX2-1NK2 homeobox 1. (370 aa)
EHMT2Euchromatic histone lysine methyltransferase 2. (1294 aa)
GLI3GLI family zinc finger 3. (1413 aa)
ISL2ISL LIM homeobox 2. (359 aa)
NKX2-2NK2 homeobox 2. (273 aa)
FEZF2FEZ family zinc finger 2. (443 aa)
HOXD10Homeobox D10. (410 aa)
NOTCH1Notch receptor 1. (2547 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
ZNF521Zinc finger protein 521. (1251 aa)
EPOPElongin BC and polycomb repressive complex 2 associated protein. (379 aa)
OLIG2Oligodendrocyte transcription factor 2. (302 aa)
MYT1LMyelin transcription factor 1 like. (1198 aa)
ATOH7Atonal bHLH transcription factor 7. (149 aa)
OLIG3Oligodendrocyte transcription factor 3. (272 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (716 aa)
ENSUAMP00000020431Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (76 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (515 aa)
ATOH1Atonal bHLH transcription factor 1. (356 aa)
GSX2GS homeobox 2. (312 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (419 aa)
ENSUAMP00000027843Uncharacterized protein. (119 aa)
ENSUAMP00000027842Uncharacterized protein. (99 aa)
DMRTA2DMRT like family A2. (514 aa)
FEVFEV transcription factor, ETS family member. (237 aa)
NKX6-2NK6 homeobox 2. (269 aa)
SOX9SRY-box transcription factor 9. (484 aa)
TLX3T cell leukemia homeobox 3. (291 aa)
ENSUAMP00000000316Homeobox domain-containing protein. (280 aa)
ENSUAMP00000000397Paired domain-containing protein. (216 aa)
HOXC10Homeobox C10. (342 aa)
ENSUAMP00000001477Uncharacterized protein. (89 aa)
PROX1Prospero homeobox 1. (737 aa)
ISL1ISL LIM homeobox 1. (349 aa)
DBX1Developing brain homeobox 1. (341 aa)
ENSUAMP00000009098C2H2-type domain-containing protein. (235 aa)
DLX1Distal-less homeobox 1. (255 aa)
DLX2Distal-less homeobox 2. (333 aa)
ENSUAMP00000010093SUFU_C domain-containing protein. (81 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (213 aa)
FOXN4Forkhead box N4. (514 aa)
FOXA1Forkhead box A1. (472 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1197 aa)
DMRT3Doublesex and mab-3 related transcription factor 3. (476 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (501 aa)
LHX3LIM homeobox 3. (403 aa)
TBR1T-box brain transcription factor 1. (682 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (757 aa)
GSX1GS homeobox 1. (263 aa)
ENSUAMP00000030304HH_signal domain-containing protein. (146 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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