STRINGSTRING
POU1F1 POU1F1 ENSUAMP00000000316 ENSUAMP00000000316 ENSUAMP00000000397 ENSUAMP00000000397 ENSUAMP00000000563 ENSUAMP00000000563 ENSUAMP00000000600 ENSUAMP00000000600 MSX1 MSX1 ENSUAMP00000001020 ENSUAMP00000001020 ENSUAMP00000001245 ENSUAMP00000001245 TBX2 TBX2 NOG NOG ENSUAMP00000001840 ENSUAMP00000001840 ENSUAMP00000001879 ENSUAMP00000001879 PROX1 PROX1 WNT11 WNT11 ENSUAMP00000003003 ENSUAMP00000003003 PRL PRL ENSUAMP00000003081 ENSUAMP00000003081 ENSUAMP00000003258 ENSUAMP00000003258 NKX2-5 NKX2-5 RARG RARG LRRC1 LRRC1 SFRP1 SFRP1 ENSUAMP00000004725 ENSUAMP00000004725 ENSUAMP00000004728 ENSUAMP00000004728 ENSUAMP00000004823 ENSUAMP00000004823 ENSUAMP00000004918 ENSUAMP00000004918 ENSUAMP00000004964 ENSUAMP00000004964 CLCN2 CLCN2 ATP2C2 ATP2C2 TWSG1 TWSG1 AIRE AIRE LSR LSR ANXA1 ANXA1 CTC1 CTC1 ENSUAMP00000006083 ENSUAMP00000006083 ESR1 ESR1 ENSUAMP00000006610 ENSUAMP00000006610 ENSUAMP00000006800 ENSUAMP00000006800 MAN2A1 MAN2A1 LATS1 LATS1 ENSUAMP00000006938 ENSUAMP00000006938 TNFSF11 TNFSF11 ENSUAMP00000006989 ENSUAMP00000006989 DKK3 DKK3 DAG1 DAG1 E2F8 E2F8 HAND2 HAND2 CDKN1B CDKN1B ORAI1 ORAI1 TP63 TP63 PTCH1 PTCH1 PLXNA1 PLXNA1 ENSUAMP00000008067 ENSUAMP00000008067 FGF10 FGF10 CRKL CRKL CAV1 CAV1 ENSUAMP00000008823 ENSUAMP00000008823 IGSF3 IGSF3 JUN JUN PTCD2 PTCD2 ENSUAMP00000009098 ENSUAMP00000009098 PIK3CA PIK3CA CEBPG CEBPG ENSUAMP00000009377 ENSUAMP00000009377 MET MET HES1 HES1 SERPINE2 SERPINE2 ENSUAMP00000009436 ENSUAMP00000009436 WNT2 WNT2 ABL1 ABL1 NODAL NODAL GCM2 GCM2 ATF2 ATF2 ASCL1 ASCL1 ENSUAMP00000010431 ENSUAMP00000010431 GPAT4 GPAT4 HOXB3 HOXB3 CADM1 CADM1 ENSUAMP00000010997 ENSUAMP00000010997 ENSUAMP00000011008 ENSUAMP00000011008 GHRHR GHRHR COBL COBL ENSUAMP00000012266 ENSUAMP00000012266 WNT3A WNT3A TGFB1 TGFB1 EAF2 EAF2 EXT1 EXT1 SMARCB1 SMARCB1 MAPK1 MAPK1 ENSUAMP00000013585 ENSUAMP00000013585 FGL1 FGL1 STAT5A STAT5A ENSUAMP00000014159 ENSUAMP00000014159 FOXA1 FOXA1 FOXN1 FOXN1 EDAR EDAR CUL3 CUL3 SERPINB5 SERPINB5 FGF7 FGF7 SRP54 SRP54 ARF6 ARF6 TNF TNF ACADM ACADM DDX55 DDX55 RHBDD3 RHBDD3 ENSUAMP00000015788 ENSUAMP00000015788 RPGRIP1L RPGRIP1L FOXF1 FOXF1 AREG AREG AGAP2 AGAP2 TGFB3 TGFB3 TGFBR1 TGFBR1 IQGAP3 IQGAP3 LHX3 LHX3 SOSTDC1 SOSTDC1 ENSUAMP00000017043 ENSUAMP00000017043 ENSUAMP00000017162 ENSUAMP00000017162 SLC6A3 SLC6A3 ARMC5 ARMC5 FA2H FA2H ENSUAMP00000017830 ENSUAMP00000017830 HOXA3 HOXA3 HOXA5 HOXA5 ENSUAMP00000017946 ENSUAMP00000017946 ENSUAMP00000017947 ENSUAMP00000017947 PYGO2 PYGO2 ZBTB7B ZBTB7B WNT10A WNT10A ENSUAMP00000018330 ENSUAMP00000018330 WDR77 WDR77 SMAD4 SMAD4 EPHA2 EPHA2 PDGFRA PDGFRA GSX2 GSX2 USF2 USF2 FEM1B FEM1B MSN MSN SERPINF1 SERPINF1 SRF SRF ESRP2 ESRP2 NOTCH4 NOTCH4 ENSUAMP00000020564 ENSUAMP00000020564 ENSUAMP00000020568 ENSUAMP00000020568 ENSUAMP00000020604 ENSUAMP00000020604 TGFB2 TGFB2 IRF6 IRF6 ENSUAMP00000021186 ENSUAMP00000021186 RB1CC1 RB1CC1 BMP2 BMP2 HNF4A HNF4A CDK5RAP3 CDK5RAP3 SLC46A2 SLC46A2 SEC63 SEC63 SIX4 SIX4 PITX1 PITX1 ADA ADA ENSUAMP00000022564 ENSUAMP00000022564 CITED2 CITED2 ENSUAMP00000022968 ENSUAMP00000022968 NEURL1 NEURL1 WT1 WT1 ENSUAMP00000023307 ENSUAMP00000023307 ENSUAMP00000023517 ENSUAMP00000023517 ENSUAMP00000023691 ENSUAMP00000023691 CREB1 CREB1 NF1 NF1 SP3 SP3 EPHB3 EPHB3 BRAF BRAF GLI1 GLI1 OTP OTP TCF21 TCF21 FRZB FRZB SULF2 SULF2 ENSUAMP00000025368 ENSUAMP00000025368 ENSUAMP00000025370 ENSUAMP00000025370 PAX8 PAX8 PCK1 PCK1 SEMA3C SEMA3C PAX1 PAX1 LRP5 LRP5 JARID2 JARID2 ZBTB1 ZBTB1 ZNF330 ZNF330 ELF3 ELF3 SOX10 SOX10 ASH1L ASH1L SOX9 SOX9 SMAD3 SMAD3 RELA RELA ENSUAMP00000027148 ENSUAMP00000027148 CEBPB CEBPB STAT6 STAT6 SMO SMO FADD FADD ELK1 ELK1 ENSUAMP00000027842 ENSUAMP00000027842 ENSUAMP00000027843 ENSUAMP00000027843 HOXB9 HOXB9 HOXB13 HOXB13 BSX BSX EZH2 EZH2 GATA3 GATA3 BMP4 BMP4 CSF1 CSF1 HNF1A HNF1A NR0B1 NR0B1 ENSUAMP00000029322 ENSUAMP00000029322 PKD2 PKD2 ZDHHC21 ZDHHC21 BCL2L11 BCL2L11 GFER GFER ZIC3 ZIC3 TGM2 TGM2 GHRH GHRH SRC SRC GSX1 GSX1 PDX1 PDX1 ENSUAMP00000030304 ENSUAMP00000030304 ENSUAMP00000030450 ENSUAMP00000030450 ENSUAMP00000030452 ENSUAMP00000030452 PROP1 PROP1 EDN1 EDN1 ENSUAMP00000030480 ENSUAMP00000030480 ASXL1 ASXL1 RAF1 RAF1 ENSUAMP00000030787 ENSUAMP00000030787 UPF2 UPF2 SLC9A3R1 SLC9A3R1 ZNF703 ZNF703 IL6 IL6 CCKBR CCKBR PCK2 PCK2 STAT5B STAT5B BTRC BTRC MAPK3 MAPK3 NKX2-3 NKX2-3 NKX2-1 NKX2-1 STRA6 STRA6 RIPK3 RIPK3 GLI3 GLI3 C6orf58 C6orf58 NKX2-2 NKX2-2 FASN FASN KDM5B KDM5B ENSUAMP00000032923 ENSUAMP00000032923 CSN2 CSN2 ENSUAMP00000033009 ENSUAMP00000033009 PML PML FOXB1 FOXB1 SOCS2 SOCS2 NR5A1 NR5A1 HOXD13 HOXD13 HOXD9 HOXD9 HOXD3 HOXD3 TAF10 TAF10 RXFP1 RXFP1 ARHGAP35 ARHGAP35 NOTCH2 NOTCH2 HLX HLX MED1 MED1 NOTCH1 NOTCH1 TNC TNC DDR1 DDR1 HIF1A HIF1A PLAG1 PLAG1 FRS2 FRS2 ACER1 ACER1 VDR VDR PHB2 PHB2 ENSUAMP00000035777 ENSUAMP00000035777 WNT3 WNT3 HESX1 HESX1 BMPR1A BMPR1A ENSUAMP00000036217 ENSUAMP00000036217 ZMPSTE24 ZMPSTE24 ENSUAMP00000036515 ENSUAMP00000036515 ENSUAMP00000036959 ENSUAMP00000036959 ENSUAMP00000036960 ENSUAMP00000036960 ENSUAMP00000036961 ENSUAMP00000036961 ALDH1A3 ALDH1A3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
POU1F1POU domain protein. (291 aa)
ENSUAMP00000000316Homeobox domain-containing protein. (280 aa)
ENSUAMP00000000397Paired domain-containing protein. (216 aa)
ENSUAMP00000000563Uncharacterized protein. (1604 aa)
ENSUAMP00000000600Uncharacterized protein. (130 aa)
MSX1Msh homeobox 1. (303 aa)
ENSUAMP00000001020Uncharacterized protein. (147 aa)
ENSUAMP00000001245CTF/NF-I domain-containing protein. (195 aa)
TBX2T-box transcription factor 2. (697 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
ENSUAMP00000001840Uncharacterized protein. (586 aa)
ENSUAMP00000001879Protein kinase domain-containing protein. (335 aa)
PROX1Prospero homeobox 1. (737 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
ENSUAMP00000003003Plexin_cytopl domain-containing protein. (490 aa)
PRLProlactin. (245 aa)
ENSUAMP00000003081Uncharacterized protein. (413 aa)
ENSUAMP00000003258Uncharacterized protein. (246 aa)
NKX2-5NK2 homeobox 5. (323 aa)
RARGRetinoic acid receptor gamma. (458 aa)
LRRC1Leucine rich repeat containing 1. (435 aa)
SFRP1Secreted frizzled related protein 1. (337 aa)
ENSUAMP00000004725G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (253 aa)
ENSUAMP00000004728G_PROTEIN_RECEP_F1_2 domain-containing protein. (155 aa)
ENSUAMP00000004823SH3 domain-containing protein. (506 aa)
ENSUAMP00000004918Homeobox domain-containing protein. (230 aa)
ENSUAMP00000004964Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1696 aa)
CLCN2Chloride channel protein. (903 aa)
ATP2C2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (931 aa)
TWSG1Twisted gastrulation BMP signaling modulator 1. (202 aa)
AIREAutoimmune regulator. (542 aa)
LSRLipolysis stimulated lipoprotein receptor. (595 aa)
ANXA1Annexin. (345 aa)
CTC1CST telomere replication complex component 1. (1227 aa)
ENSUAMP00000006083Dynein assembly factor 1, axonemal. (316 aa)
ESR1Estrogen receptor 1. (490 aa)
ENSUAMP00000006610CUT domain-containing protein. (259 aa)
ENSUAMP00000006800Uncharacterized protein. (97 aa)
MAN2A1Alpha-mannosidase. (1096 aa)
LATS1Uncharacterized protein. (1012 aa)
ENSUAMP00000006938Uncharacterized protein. (133 aa)
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (242 aa)
ENSUAMP00000006989CTF/NF-I domain-containing protein. (213 aa)
DKK3Dickkopf WNT signaling pathway inhibitor 3. (361 aa)
DAG1Dystroglycan 1. (892 aa)
E2F8E2F transcription factor 8. (863 aa)
HAND2Heart and neural crest derivatives expressed 2. (217 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (200 aa)
ORAI1ORAI calcium release-activated calcium modulator 1. (305 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
PTCH1Patched 1. (1453 aa)
PLXNA1Plexin A1. (1852 aa)
ENSUAMP00000008067BAAT_C domain-containing protein. (197 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
ENSUAMP00000008823TAN domain-containing protein. (111 aa)
IGSF3Immunoglobulin superfamily member 3. (1202 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa)
PTCD2Pentatricopeptide repeat domain 2. (427 aa)
ENSUAMP00000009098C2H2-type domain-containing protein. (235 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
CEBPGCCAAT enhancer binding protein gamma. (147 aa)
ENSUAMP00000009377Uncharacterized protein. (170 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1399 aa)
HES1Hes family bHLH transcription factor 1. (259 aa)
SERPINE2Serpin family E member 2; Belongs to the serpin family. (232 aa)
ENSUAMP00000009436HECT domain-containing protein. (51 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
ABL1Tyrosine-protein kinase. (1138 aa)
NODALNodal growth differentiation factor. (348 aa)
GCM2Glial cells missing transcription factor 2. (506 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (213 aa)
ENSUAMP00000010431Uncharacterized protein. (415 aa)
GPAT4Glycerol-3-phosphate acyltransferase 4. (456 aa)
HOXB3Homeobox B3. (254 aa)
CADM1Cell adhesion molecule 1. (339 aa)
ENSUAMP00000010997TPR_REGION domain-containing protein. (150 aa)
ENSUAMP00000011008Uncharacterized protein. (538 aa)
GHRHRGrowth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (422 aa)
COBLCordon-bleu WH2 repeat protein. (1250 aa)
ENSUAMP00000012266CTNNB1_binding domain-containing protein. (162 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (356 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
EAF2ELL associated factor 2. (249 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (506 aa)
SMARCB1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (385 aa)
MAPK1Mitogen-activated protein kinase. (364 aa)
ENSUAMP00000013585Uncharacterized protein. (588 aa)
FGL1Fibrinogen like 1. (312 aa)
STAT5ASignal transducer and activator of transcription. (797 aa)
ENSUAMP00000014159Uncharacterized protein. (78 aa)
FOXA1Forkhead box A1. (472 aa)
FOXN1Forkhead box N1. (634 aa)
EDAREctodysplasin A receptor. (475 aa)
CUL3Cullin 3; Belongs to the cullin family. (766 aa)
SERPINB5Serpin family B member 5; Belongs to the serpin family. (375 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
SRP54Signal recognition particle 54. (262 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (230 aa)
ACADMAcyl-CoA dehydrogenase medium chain. (421 aa)
DDX55RNA helicase. (600 aa)
RHBDD3Rhomboid domain containing 3. (386 aa)
ENSUAMP00000015788BZIP domain-containing protein. (359 aa)
RPGRIP1LRPGRIP1 like. (1207 aa)
FOXF1Forkhead box F1. (379 aa)
AREGAmphiregulin. (257 aa)
AGAP2ArfGAP with GTPase domain, ankyrin repeat and PH domain 2. (733 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (501 aa)
IQGAP3IQ motif containing GTPase activating protein 3. (1630 aa)
LHX3LIM homeobox 3. (403 aa)
SOSTDC1Sclerostin domain containing 1. (206 aa)
ENSUAMP00000017043HNF-1_N domain-containing protein. (138 aa)
ENSUAMP00000017162Uncharacterized protein. (137 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (617 aa)
ARMC5Armadillo repeat containing 5. (943 aa)
FA2HFatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (372 aa)
ENSUAMP00000017830Uncharacterized protein. (157 aa)
HOXA3Homeobox A3. (419 aa)
HOXA5Homeobox A5. (381 aa)
ENSUAMP00000017946Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (272 aa)
ENSUAMP00000017947Uncharacterized protein. (283 aa)
PYGO2Pygopus family PHD finger 2. (369 aa)
ZBTB7BZinc finger and BTB domain containing 7B. (507 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
ENSUAMP00000018330Uncharacterized protein. (346 aa)
WDR77WD repeat domain 77. (342 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
EPHA2EPH receptor A2. (966 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
GSX2GS homeobox 2. (312 aa)
USF2Upstream transcription factor 2, c-fos interacting. (335 aa)
FEM1BFem-1 homolog B. (627 aa)
MSNMoesin. (577 aa)
SERPINF1Serpin family F member 1; Belongs to the serpin family. (418 aa)
SRFSerum response factor. (507 aa)
ESRP2Epithelial splicing regulatory protein 2. (699 aa)
NOTCH4Notch receptor 4. (1894 aa)
ENSUAMP00000020564HHH_8 domain-containing protein. (107 aa)
ENSUAMP00000020568DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (181 aa)
ENSUAMP00000020604Uncharacterized protein. (334 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (439 aa)
IRF6Interferon regulatory factor 6. (462 aa)
ENSUAMP00000021186Uncharacterized protein. (404 aa)
RB1CC1RB1 inducible coiled-coil 1. (1273 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
HNF4AHepatocyte nuclear factor 4 alpha. (474 aa)
CDK5RAP3CDK5 regulatory subunit associated protein 3. (504 aa)
SLC46A2Solute carrier family 46 member 2. (484 aa)
SEC63SEC63 homolog, protein translocation regulator. (686 aa)
SIX4SIX homeobox 4. (783 aa)
PITX1Homeobox protein. (313 aa)
ADAAdenosine deaminase. (385 aa)
ENSUAMP00000022564HNF-1B_C domain-containing protein. (134 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa)
ENSUAMP00000022968Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (422 aa)
NEURL1Neuralized E3 ubiquitin protein ligase 1. (575 aa)
WT1WT1 transcription factor. (522 aa)
ENSUAMP00000023307Uncharacterized protein. (243 aa)
ENSUAMP00000023517Laminin N-terminal domain-containing protein. (378 aa)
ENSUAMP00000023691Uncharacterized protein. (268 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
NF1Neurofibromin 1. (2845 aa)
SP3Sp3 transcription factor. (780 aa)
EPHB3EPH receptor B3. (1000 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (728 aa)
GLI1GLI family zinc finger 1. (1105 aa)
OTPOrthopedia homeobox. (325 aa)
TCF21Transcription factor 21. (179 aa)
FRZBFrizzled related protein. (298 aa)
SULF2Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (870 aa)
ENSUAMP00000025368TNFR-Cys domain-containing protein. (263 aa)
ENSUAMP00000025370Uncharacterized protein. (358 aa)
PAX8Paired box 8. (458 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
SEMA3CSemaphorin 3C; Belongs to the semaphorin family. (750 aa)
PAX1Paired box 1. (432 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1606 aa)
JARID2Jumonji and AT-rich interaction domain containing 2. (1160 aa)
ZBTB1Zinc finger and BTB domain containing 1. (644 aa)
ZNF330Zinc finger protein 330. (320 aa)
ELF3E74 like ETS transcription factor 3. (369 aa)
SOX10SRY-box transcription factor 10. (465 aa)
ASH1LASH1 like histone lysine methyltransferase. (2965 aa)
SOX9SRY-box transcription factor 9. (484 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
RELARELA proto-oncogene, NF-kB subunit. (508 aa)
ENSUAMP00000027148Uncharacterized protein. (221 aa)
CEBPBCCAAT/enhancer-binding protein. (346 aa)
STAT6Signal transducer and activator of transcription. (844 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (788 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (220 aa)
ELK1ETS transcription factor ELK1. (435 aa)
ENSUAMP00000027842Uncharacterized protein. (99 aa)
ENSUAMP00000027843Uncharacterized protein. (119 aa)
HOXB9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (250 aa)
HOXB13Homeobox B13. (285 aa)
BSXBrain specific homeobox. (232 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (746 aa)
GATA3GATA binding protein 3. (444 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
CSF1Colony stimulating factor 1. (518 aa)
HNF1AHNF1 homeobox A. (631 aa)
NR0B1Nuclear receptor subfamily 0 group B member 1. (471 aa)
ENSUAMP00000029322Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (102 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (897 aa)
ZDHHC21Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa)
BCL2L11BCL2 like 11. (140 aa)
GFERSulfhydryl oxidase. (206 aa)
ZIC3Uncharacterized protein. (466 aa)
TGM2Transglutaminase 2. (687 aa)
GHRHGrowth hormone releasing hormone. (106 aa)
SRCTyrosine-protein kinase. (557 aa)
GSX1GS homeobox 1. (263 aa)
PDX1Pancreatic and duodenal homeobox 1. (282 aa)
ENSUAMP00000030304HH_signal domain-containing protein. (146 aa)
ENSUAMP00000030450Uncharacterized protein. (1283 aa)
ENSUAMP00000030452Uncharacterized protein. (144 aa)
PROP1PROP paired-like homeobox 1. (215 aa)
EDN1Endothelin 1. (202 aa)
ENSUAMP00000030480HARE-HTH domain-containing protein. (88 aa)
ASXL1ASXL transcriptional regulator 1. (1306 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (564 aa)
ENSUAMP00000030787Uncharacterized protein. (84 aa)
UPF2UPF2 regulator of nonsense mediated mRNA decay. (1205 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (366 aa)
ZNF703Zinc finger protein 703. (592 aa)
IL6Interleukin 6. (212 aa)
CCKBRCholecystokinin B receptor; Belongs to the G-protein coupled receptor 1 family. (444 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (640 aa)
STAT5BSignal transducer and activator of transcription. (784 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
MAPK3Mitogen-activated protein kinase. (354 aa)
NKX2-3NK2 homeobox 3. (318 aa)
NKX2-1NK2 homeobox 1. (370 aa)
STRA6Stimulated by retinoic acid 6. (642 aa)
RIPK3Receptor interacting serine/threonine kinase 3; Belongs to the protein kinase superfamily. (451 aa)
GLI3GLI family zinc finger 3. (1413 aa)
C6orf58Chromosome 6 open reading frame 58. (314 aa)
NKX2-2NK2 homeobox 2. (273 aa)
FASNFatty acid synthase. (2519 aa)
KDM5BLysine demethylase 5B. (1039 aa)
ENSUAMP00000032923Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (387 aa)
CSN2Casein beta. (220 aa)
ENSUAMP00000033009Uncharacterized protein. (1337 aa)
PMLPromyelocytic leukemia. (877 aa)
FOXB1Forkhead box B1. (325 aa)
SOCS2Suppressor of cytokine signaling 2. (198 aa)
NR5A1Nuclear receptor subfamily 5 group A member 1. (461 aa)
HOXD13Homeobox D13. (333 aa)
HOXD9Homeobox D9. (341 aa)
HOXD3Homeobox D3. (432 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (199 aa)
RXFP1Relaxin family peptide receptor 1. (724 aa)
ARHGAP35Rho GTPase activating protein 35. (1500 aa)
NOTCH2Notch receptor 2. (2374 aa)
HLXH2.0 like homeobox. (454 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1477 aa)
NOTCH1Notch receptor 1. (2547 aa)
TNCTenascin C. (2201 aa)
DDR1Discoidin domain receptor tyrosine kinase 1. (936 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (823 aa)
PLAG1PLAG1 zinc finger. (499 aa)
FRS2Fibroblast growth factor receptor substrate 2. (507 aa)
ACER1Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (263 aa)
VDRVitamin D receptor. (427 aa)
PHB2Prohibitin. (297 aa)
ENSUAMP00000035777HMG box domain-containing protein. (191 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (338 aa)
HESX1HESX homeobox 1. (185 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
ENSUAMP00000036217Uncharacterized protein. (186 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
ENSUAMP00000036515Uncharacterized protein. (78 aa)
ENSUAMP00000036959Uncharacterized protein. (563 aa)
ENSUAMP00000036960Uncharacterized protein. (136 aa)
ENSUAMP00000036961Uncharacterized protein. (86 aa)
ALDH1A3Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family. (512 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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