STRINGSTRING
ENSUAMP00000009377 ENSUAMP00000009377 HTR2B HTR2B GDF2 GDF2 ENSUAMP00000000316 ENSUAMP00000000316 IL10 IL10 ENSUAMP00000000397 ENSUAMP00000000397 CDKN2B CDKN2B ENSUAMP00000000737 ENSUAMP00000000737 ENSUAMP00000000744 ENSUAMP00000000744 ENSUAMP00000001020 ENSUAMP00000001020 ENSUAMP00000001068 ENSUAMP00000001068 ENSUAMP00000001245 ENSUAMP00000001245 TIE1 TIE1 JCAD JCAD CCL24 CCL24 NOG NOG ENSUAMP00000001692 ENSUAMP00000001692 TNMD TNMD ENSUAMP00000001879 ENSUAMP00000001879 AQP11 AQP11 ZEB1 ZEB1 PROX1 PROX1 MTSS1 MTSS1 ENSUAMP00000002943 ENSUAMP00000002943 ZNF304 ZNF304 ENSUAMP00000003081 ENSUAMP00000003081 ENSUAMP00000003258 ENSUAMP00000003258 ENSUAMP00000003397 ENSUAMP00000003397 FGFBP1 FGFBP1 VIP VIP ENSUAMP00000003693 ENSUAMP00000003693 SRSF6 SRSF6 RREB1 RREB1 SFRP1 SFRP1 ENSUAMP00000004542 ENSUAMP00000004542 SCG2 SCG2 FGF9 FGF9 PDGFB PDGFB ENSUAMP00000004918 ENSUAMP00000004918 FLT4 FLT4 ENSUAMP00000005111 ENSUAMP00000005111 A4GNT A4GNT HPN HPN DUSP10 DUSP10 ENSUAMP00000005897 ENSUAMP00000005897 ENSUAMP00000005900 ENSUAMP00000005900 ENSUAMP00000006566 ENSUAMP00000006566 ENSUAMP00000006607 ENSUAMP00000006607 ENSUAMP00000006800 ENSUAMP00000006800 CDH13 CDH13 ENSUAMP00000006968 ENSUAMP00000006968 ENSUAMP00000006973 ENSUAMP00000006973 ENSUAMP00000006989 ENSUAMP00000006989 GRN GRN CDKN1B CDKN1B ENSUAMP00000007637 ENSUAMP00000007637 TP63 TP63 PTCH1 PTCH1 ENSUAMP00000007969 ENSUAMP00000007969 FGF10 FGF10 CDK6 CDK6 CAV2 CAV2 CAV1 CAV1 STAT3 STAT3 TACSTD2 TACSTD2 JUN JUN ENSUAMP00000009098 ENSUAMP00000009098 HMX2 HMX2 HES1 HES1 WNT2 WNT2 ENSUAMP00000009578 ENSUAMP00000009578 GDF5 GDF5 PRKD1 PRKD1 IL26 IL26 NODAL NODAL ENSUAMP00000010431 ENSUAMP00000010431 VASH2 VASH2 PRKCA PRKCA AKT1 AKT1 CDC73 CDC73 FGFR3 FGFR3 ENSUAMP00000011212 ENSUAMP00000011212 PHOX2B PHOX2B AKT3 AKT3 ENSUAMP00000012044 ENSUAMP00000012044 ZFP36 ZFP36 TGFB1 TGFB1 NUPR1 NUPR1 ENSUAMP00000012642 ENSUAMP00000012642 PDCL3 PDCL3 ENSUAMP00000012947 ENSUAMP00000012947 ENSUAMP00000012990 ENSUAMP00000012990 FUT2 FUT2 FUT1 FUT1 EAF2 EAF2 ENSUAMP00000013328 ENSUAMP00000013328 ZFP36L1 ZFP36L1 ENSUAMP00000013585 ENSUAMP00000013585 SP1 SP1 STAT5A STAT5A NKX2-6 NKX2-6 VEGFC VEGFC MAGED1 MAGED1 APLNR APLNR VASH1 VASH1 CLDN1 CLDN1 RB1 RB1 ATOH8 ATOH8 SERPINB5 SERPINB5 FGF7 FGF7 TBC1D31 TBC1D31 TNF TNF ENSUAMP00000015788 ENSUAMP00000015788 ERRFI1 ERRFI1 ENSUAMP00000015993 ENSUAMP00000015993 ENSUAMP00000016192 ENSUAMP00000016192 ENSUAMP00000016279 ENSUAMP00000016279 PDPK1 PDPK1 AGAP2 AGAP2 ENSUAMP00000016646 ENSUAMP00000016646 WDR13 WDR13 TGFBR1 TGFBR1 IQGAP3 IQGAP3 PGF PGF ENSUAMP00000017364 ENSUAMP00000017364 ENSUAMP00000017478 ENSUAMP00000017478 ACVRL1 ACVRL1 ENSUAMP00000017524 ENSUAMP00000017524 EMC10 EMC10 FA2H FA2H BRCA2 BRCA2 PPARD PPARD IFT74 IFT74 HOXA5 HOXA5 PYGO2 PYGO2 ECM1 ECM1 WDR77 WDR77 UHRF1 UHRF1 SNAI2 SNAI2 BAD BAD ENSUAMP00000019227 ENSUAMP00000019227 VEGFB VEGFB NR1D1 NR1D1 PIK3CD PIK3CD HMOX1 HMOX1 SERPINF1 SERPINF1 TRIM24 TRIM24 HSF4 HSF4 VEGFA VEGFA ESRP2 ESRP2 EYA1 EYA1 ENSUAMP00000020431 ENSUAMP00000020431 PTPRK PTPRK TGFB2 TGFB2 ENSUAMP00000020951 ENSUAMP00000020951 IRF6 IRF6 DLL4 DLL4 SIRT1 SIRT1 PRKD2 PRKD2 BMP2 BMP2 GPC3 GPC3 PDCD10 PDCD10 APOH APOH THBS1 THBS1 SIX4 SIX4 LEP LEP MTA3 MTA3 STK4 STK4 FGFR2 FGFR2 CCL26 CCL26 KDR KDR ATP5F1A ATP5F1A SLURP1 SLURP1 NGFR NGFR B2M B2M NF1 NF1 LRG1 LRG1 SIRT6 SIRT6 GLI1 GLI1 SULF2 SULF2 ENSUAMP00000025050 ENSUAMP00000025050 RTN4 RTN4 ENSUAMP00000025300 ENSUAMP00000025300 ENSUAMP00000025477 ENSUAMP00000025477 ALOX5 ALOX5 ZNF580 ZNF580 FGFR1 FGFR1 ENSUAMP00000025690 ENSUAMP00000025690 WDR48 WDR48 FMC1 FMC1 TCF7L2 TCF7L2 INTU INTU SOX9 SOX9 SMAD3 SMAD3 OVOL1 OVOL1 PTN PTN ENSUAMP00000026963 ENSUAMP00000026963 OSR2 OSR2 ENSUAMP00000026993 ENSUAMP00000026993 TNFAIP3 TNFAIP3 CNMD CNMD BIRC5 BIRC5 SMO SMO ENSUAMP00000027617 ENSUAMP00000027617 SULF1 SULF1 NRARP NRARP ENSUAMP00000027914 ENSUAMP00000027914 F3 F3 DAB2IP DAB2IP DEAF1 DEAF1 PDCD6 PDCD6 GATA3 GATA3 BMP4 BMP4 ENSUAMP00000029322 ENSUAMP00000029322 MCC MCC DLX6 DLX6 DLX5 DLX5 MEF2C MEF2C FGF1 FGF1 THBS4 THBS4 PDX1 PDX1 FLT1 FLT1 ENSUAMP00000030304 ENSUAMP00000030304 APOE APOE ZNF703 ZNF703 ENSUAMP00000031224 ENSUAMP00000031224 NKX2-3 NKX2-3 NKX2-8 NKX2-8 MYC MYC DLG1 DLG1 TINF2 TINF2 TGM1 TGM1 SYNJ2BP SYNJ2BP AIMP1 AIMP1 GHRL GHRL SAV1 SAV1 EGR3 EGR3 KDM5B KDM5B ENSUAMP00000032909 ENSUAMP00000032909 FZD7 FZD7 ENSUAMP00000032923 ENSUAMP00000032923 MYDGF MYDGF ENSUAMP00000033583 ENSUAMP00000033583 B4GALT1 B4GALT1 NOTCH2 NOTCH2 HLX HLX MED1 MED1 NOTCH1 NOTCH1 CDH3 CDH3 STAT1 STAT1 SFN SFN KDF1 KDF1 JAG1 JAG1 IFT52 IFT52 OSR1 OSR1 FRS2 FRS2 ENSUAMP00000034912 ENSUAMP00000034912 PROK1 PROK1 VDR VDR PHB2 PHB2 WNT10B WNT10B IFT80 IFT80 ST8SIA1 ST8SIA1 C5AR1 C5AR1 C5AR2 C5AR2 ENSUAMP00000036162 ENSUAMP00000036162 BMPR1A BMPR1A ENSUAMP00000036324 ENSUAMP00000036324 LIMS2 LIMS2 BMPR2 BMPR2 ENSUAMP00000037141 ENSUAMP00000037141 AKT2 AKT2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSUAMP00000009377Uncharacterized protein. (170 aa)
HTR2B5-hydroxytryptamine receptor 2B. (480 aa)
GDF2Growth differentiation factor 2. (429 aa)
ENSUAMP00000000316Homeobox domain-containing protein. (280 aa)
IL10Interleukin 10. (178 aa)
ENSUAMP00000000397Paired domain-containing protein. (216 aa)
CDKN2BCyclin dependent kinase inhibitor 2B. (138 aa)
ENSUAMP00000000737Uncharacterized protein. (81 aa)
ENSUAMP00000000744Uncharacterized protein. (157 aa)
ENSUAMP00000001020Uncharacterized protein. (147 aa)
ENSUAMP00000001068Ig-like domain-containing protein. (174 aa)
ENSUAMP00000001245CTF/NF-I domain-containing protein. (195 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1069 aa)
JCADJunctional cadherin 5 associated. (1372 aa)
CCL24C-C motif chemokine ligand 24. (119 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
ENSUAMP00000001692L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (147 aa)
TNMDTenomodulin. (310 aa)
ENSUAMP00000001879Protein kinase domain-containing protein. (335 aa)
AQP11Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. (272 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1017 aa)
PROX1Prospero homeobox 1. (737 aa)
MTSS1MTSS I-BAR domain containing 1. (686 aa)
ENSUAMP00000002943RNAse_Pc domain-containing protein; Belongs to the pancreatic ribonuclease family. (169 aa)
ZNF304Zinc finger protein 304. (617 aa)
ENSUAMP00000003081Uncharacterized protein. (413 aa)
ENSUAMP00000003258Uncharacterized protein. (246 aa)
ENSUAMP00000003397G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (350 aa)
FGFBP1Fibroblast growth factor binding protein 1. (255 aa)
VIPVasoactive intestinal peptide. (170 aa)
ENSUAMP00000003693Uncharacterized protein. (166 aa)
SRSF6Serine and arginine rich splicing factor 6. (344 aa)
RREB1Ras responsive element binding protein 1. (1767 aa)
SFRP1Secreted frizzled related protein 1. (337 aa)
ENSUAMP00000004542Uncharacterized protein. (171 aa)
SCG2Secretogranin II. (618 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
ENSUAMP00000004918Homeobox domain-containing protein. (230 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1363 aa)
ENSUAMP00000005111Aldedh domain-containing protein. (208 aa)
A4GNTAlpha-1,4-N-acetylglucosaminyltransferase. (339 aa)
HPNHepsin; Belongs to the peptidase S1 family. (417 aa)
DUSP10Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa)
ENSUAMP00000005897G_PROTEIN_RECEP_F1_2 domain-containing protein. (80 aa)
ENSUAMP00000005900G_PROTEIN_RECEP_F1_2 domain-containing protein. (285 aa)
ENSUAMP00000006566UDENN FLCN/SMCR8-type domain-containing protein. (579 aa)
ENSUAMP00000006607Uncharacterized protein. (215 aa)
ENSUAMP00000006800Uncharacterized protein. (97 aa)
CDH13Cadherin 13. (495 aa)
ENSUAMP00000006968Protein kinase domain-containing protein. (75 aa)
ENSUAMP00000006973Protein kinase domain-containing protein. (104 aa)
ENSUAMP00000006989CTF/NF-I domain-containing protein. (213 aa)
GRNGranulin precursor. (587 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (200 aa)
ENSUAMP00000007637Uncharacterized protein. (172 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
PTCH1Patched 1. (1453 aa)
ENSUAMP00000007969Uncharacterized protein. (166 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
TACSTD2Tumor associated calcium signal transducer 2. (323 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa)
ENSUAMP00000009098C2H2-type domain-containing protein. (235 aa)
HMX2H6 family homeobox 2. (273 aa)
HES1Hes family bHLH transcription factor 1. (259 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
ENSUAMP00000009578RNAse_Pc domain-containing protein; Belongs to the pancreatic ribonuclease family. (169 aa)
GDF5Growth differentiation factor 5. (499 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (848 aa)
IL26Interleukin 26. (171 aa)
NODALNodal growth differentiation factor. (348 aa)
ENSUAMP00000010431Uncharacterized protein. (415 aa)
VASH2Vasohibin 2. (392 aa)
PRKCAProtein kinase C alpha; Belongs to the protein kinase superfamily. (484 aa)
AKT1Non-specific serine/threonine protein kinase. (572 aa)
CDC73Cell division cycle 73. (519 aa)
FGFR3Fibroblast growth factor receptor. (691 aa)
ENSUAMP00000011212G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (370 aa)
PHOX2BPaired like homeobox 2B. (289 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
ENSUAMP00000012044TGF_BETA_2 domain-containing protein. (154 aa)
ZFP36ZFP36 ring finger protein. (325 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
NUPR1Nuclear protein 1, transcriptional regulator. (82 aa)
ENSUAMP00000012642Integrin_alpha2 domain-containing protein. (261 aa)
PDCL3Phosducin like 3. (222 aa)
ENSUAMP00000012947Uncharacterized protein. (103 aa)
ENSUAMP00000012990L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (348 aa)
FUT2L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (339 aa)
FUT1L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (319 aa)
EAF2ELL associated factor 2. (249 aa)
ENSUAMP00000013328Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (237 aa)
ZFP36L1ZFP36 ring finger protein like 1. (338 aa)
ENSUAMP00000013585Uncharacterized protein. (588 aa)
SP1Sp1 transcription factor. (780 aa)
STAT5ASignal transducer and activator of transcription. (797 aa)
NKX2-6NK2 homeobox 6. (268 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (391 aa)
MAGED1MAGE family member D1. (821 aa)
APLNRApelin receptor; Belongs to the G-protein coupled receptor 1 family. (380 aa)
VASH1Vasohibin 1. (289 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (216 aa)
RB1RB transcriptional corepressor 1. (870 aa)
ATOH8Atonal bHLH transcription factor 8. (322 aa)
SERPINB5Serpin family B member 5; Belongs to the serpin family. (375 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
TBC1D31TBC1 domain family member 31. (923 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (230 aa)
ENSUAMP00000015788BZIP domain-containing protein. (359 aa)
ERRFI1ERBB receptor feedback inhibitor 1. (410 aa)
ENSUAMP00000015993Uncharacterized protein. (98 aa)
ENSUAMP00000016192Integrin beta; Belongs to the integrin beta chain family. (786 aa)
ENSUAMP00000016279Uncharacterized protein. (85 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (531 aa)
AGAP2ArfGAP with GTPase domain, ankyrin repeat and PH domain 2. (733 aa)
ENSUAMP00000016646Uncharacterized protein. (167 aa)
WDR13WD repeat domain 13. (423 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (501 aa)
IQGAP3IQ motif containing GTPase activating protein 3. (1630 aa)
PGFPlacental growth factor; Belongs to the PDGF/VEGF growth factor family. (170 aa)
ENSUAMP00000017364Uncharacterized protein. (53 aa)
ENSUAMP00000017478Guanylate kinase-like domain-containing protein. (307 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (518 aa)
ENSUAMP00000017524Uncharacterized protein. (542 aa)
EMC10ER membrane protein complex subunit 10. (254 aa)
FA2HFatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (372 aa)
BRCA2BRCA2 DNA repair associated. (3458 aa)
PPARDPeroxisome proliferator activated receptor delta. (441 aa)
IFT74Intraflagellar transport 74. (603 aa)
HOXA5Homeobox A5. (381 aa)
PYGO2Pygopus family PHD finger 2. (369 aa)
ECM1Extracellular matrix protein 1. (422 aa)
WDR77WD repeat domain 77. (342 aa)
UHRF1Ubiquitin like with PHD and ring finger domains 1. (812 aa)
SNAI2Snail family transcriptional repressor 2. (230 aa)
BADBCL2 associated agonist of cell death. (168 aa)
ENSUAMP00000019227Uncharacterized protein. (61 aa)
VEGFBVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (191 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (600 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1041 aa)
HMOX1Heme oxygenase 1. (288 aa)
SERPINF1Serpin family F member 1; Belongs to the serpin family. (418 aa)
TRIM24Tripartite motif containing 24. (1021 aa)
HSF4Heat shock transcription factor 4. (492 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (516 aa)
ESRP2Epithelial splicing regulatory protein 2. (699 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (515 aa)
ENSUAMP00000020431Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (76 aa)
PTPRKUncharacterized protein. (786 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (439 aa)
ENSUAMP00000020951IF rod domain-containing protein; Belongs to the intermediate filament family. (532 aa)
IRF6Interferon regulatory factor 6. (462 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (716 aa)
SIRT1Sirtuin 1. (618 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (840 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
GPC3Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (496 aa)
PDCD10Programmed cell death 10. (212 aa)
APOHApolipoprotein H. (345 aa)
THBS1Thrombospondin 1. (1170 aa)
SIX4SIX homeobox 4. (783 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (157 aa)
MTA3Metastasis associated 1 family member 3. (589 aa)
STK4Serine/threonine kinase 4. (487 aa)
FGFR2Fibroblast growth factor receptor 2. (661 aa)
CCL26C-C motif chemokine. (92 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1282 aa)
ATP5F1AATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (578 aa)
SLURP1Secreted LY6/PLAUR domain containing 1. (120 aa)
NGFRNerve growth factor receptor. (388 aa)
B2MBeta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (118 aa)
NF1Neurofibromin 1. (2845 aa)
LRG1Leucine rich alpha-2-glycoprotein 1. (354 aa)
SIRT6Sirtuin 6. (338 aa)
GLI1GLI family zinc finger 1. (1105 aa)
SULF2Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (870 aa)
ENSUAMP00000025050Uncharacterized protein. (456 aa)
RTN4Reticulon. (951 aa)
ENSUAMP00000025300Non-specific serine/threonine protein kinase. (254 aa)
ENSUAMP00000025477Uncharacterized protein. (185 aa)
ALOX5Arachidonate 5-lipoxygenase. (674 aa)
ZNF580Zinc finger protein 580. (199 aa)
FGFR1Fibroblast growth factor receptor. (848 aa)
ENSUAMP00000025690Runt domain-containing protein. (196 aa)
WDR48WD repeat domain 48. (626 aa)
FMC1Formation of mitochondrial complex V assembly factor 1 homolog. (113 aa)
TCF7L2Transcription factor 7 like 2. (524 aa)
INTUInturned planar cell polarity protein. (909 aa)
SOX9SRY-box transcription factor 9. (484 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
OVOL1Ovo like transcriptional repressor 1. (247 aa)
PTNPleiotrophin. (218 aa)
ENSUAMP00000026963Protein kinase domain-containing protein. (93 aa)
OSR2Odd-skipped related transciption factor 2. (312 aa)
ENSUAMP00000026993Uncharacterized protein. (118 aa)
TNFAIP3TNF alpha induced protein 3. (790 aa)
CNMDChondromodulin. (340 aa)
BIRC5Baculoviral IAP repeat containing 5. (142 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (788 aa)
ENSUAMP00000027617SEA domain-containing protein. (259 aa)
SULF1Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (940 aa)
NRARPNOTCH regulated ankyrin repeat protein. (114 aa)
ENSUAMP00000027914Uncharacterized protein. (75 aa)
F3Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. (288 aa)
DAB2IPDAB2 interacting protein. (1100 aa)
DEAF1DEAF1 transcription factor. (544 aa)
PDCD6Programmed cell death 6. (189 aa)
GATA3GATA binding protein 3. (444 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
ENSUAMP00000029322Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (102 aa)
MCCMCC regulator of WNT signaling pathway. (998 aa)
DLX6Distal-less homeobox 6. (291 aa)
DLX5Distal-less homeobox 5. (289 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
THBS4Thrombospondin 4. (944 aa)
PDX1Pancreatic and duodenal homeobox 1. (282 aa)
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1265 aa)
ENSUAMP00000030304HH_signal domain-containing protein. (146 aa)
APOEApolipoprotein E. (323 aa)
ZNF703Zinc finger protein 703. (592 aa)
ENSUAMP00000031224Uncharacterized protein. (323 aa)
NKX2-3NK2 homeobox 3. (318 aa)
NKX2-8NK2 homeobox 8. (239 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (806 aa)
TINF2TERF1 interacting nuclear factor 2. (452 aa)
TGM1Transglutaminase 1. (819 aa)
SYNJ2BPSynaptojanin 2 binding protein. (142 aa)
AIMP1Aminoacyl tRNA synthetase complex interacting multifunctional protein 1. (320 aa)
GHRLGhrelin and obestatin prepropeptide. (134 aa)
SAV1Salvador family WW domain containing protein 1. (384 aa)
EGR3Early growth response 3. (387 aa)
KDM5BLysine demethylase 5B. (1039 aa)
ENSUAMP00000032909Uncharacterized protein. (592 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
ENSUAMP00000032923Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (387 aa)
MYDGFMyeloid derived growth factor. (173 aa)
ENSUAMP00000033583Uncharacterized protein. (659 aa)
B4GALT1Beta-1,4-galactosyltransferase 1. (400 aa)
NOTCH2Notch receptor 2. (2374 aa)
HLXH2.0 like homeobox. (454 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1477 aa)
NOTCH1Notch receptor 1. (2547 aa)
CDH3Cadherin 3; Cadherins are calcium-dependent cell adhesion proteins. (856 aa)
STAT1Signal transducer and activator of transcription. (824 aa)
SFNStratifin; Belongs to the 14-3-3 family. (248 aa)
KDF1Keratinocyte differentiation factor 1. (397 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1226 aa)
IFT52Intraflagellar transport 52. (467 aa)
OSR1Odd-skipped related transcription factor 1. (267 aa)
FRS2Fibroblast growth factor receptor substrate 2. (507 aa)
ENSUAMP00000034912Uncharacterized protein. (714 aa)
PROK1Prokineticin 1. (105 aa)
VDRVitamin D receptor. (427 aa)
PHB2Prohibitin. (297 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
IFT80Intraflagellar transport 80. (768 aa)
ST8SIA1ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (249 aa)
C5AR1Complement C5a receptor 1; Belongs to the G-protein coupled receptor 1 family. (350 aa)
C5AR2Complement component 5a receptor 2. (337 aa)
ENSUAMP00000036162Protein kinase domain-containing protein. (462 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
ENSUAMP00000036324Uncharacterized protein. (189 aa)
LIMS2LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (341 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (857 aa)
ENSUAMP00000037141Uncharacterized protein. (54 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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