STRINGSTRING
ENSUAMP00000000119 ENSUAMP00000000119 ENSUAMP00000000198 ENSUAMP00000000198 TRIM21 TRIM21 HEYL HEYL ENSUAMP00000000316 ENSUAMP00000000316 IL10 IL10 ENSUAMP00000000397 ENSUAMP00000000397 ENSUAMP00000000603 ENSUAMP00000000603 MSX1 MSX1 ENSUAMP00000000621 ENSUAMP00000000621 LFNG LFNG ENSUAMP00000000765 ENSUAMP00000000765 ENSUAMP00000001140 ENSUAMP00000001140 ENSUAMP00000001162 ENSUAMP00000001162 ENSUAMP00000001173 ENSUAMP00000001173 HIPK2 HIPK2 EGF EGF ENSUAMP00000001632 ENSUAMP00000001632 NOG NOG ENSUAMP00000001690 ENSUAMP00000001690 EDF1 EDF1 RSF1 RSF1 ENSUAMP00000002126 ENSUAMP00000002126 ENSUAMP00000002297 ENSUAMP00000002297 ZNF304 ZNF304 ENSUAMP00000003003 ENSUAMP00000003003 ENSUAMP00000003383 ENSUAMP00000003383 PLAUR PLAUR ENSUAMP00000003703 ENSUAMP00000003703 SNAPIN SNAPIN ENSUAMP00000004097 ENSUAMP00000004097 TRIM28 TRIM28 ENSUAMP00000004664 ENSUAMP00000004664 MED25 MED25 TRIB3 TRIB3 ENSUAMP00000005048 ENSUAMP00000005048 TEX14 TEX14 ENSUAMP00000006064 ENSUAMP00000006064 NCBP1 NCBP1 ENSUAMP00000006350 ENSUAMP00000006350 TFAP4 TFAP4 ENSUAMP00000006607 ENSUAMP00000006607 HIP1R HIP1R ENSUAMP00000006851 ENSUAMP00000006851 TTBK1 TTBK1 APP APP TNFSF11 TNFSF11 ENSUAMP00000007257 ENSUAMP00000007257 HAND2 HAND2 ENSUAMP00000007483 ENSUAMP00000007483 PON1 PON1 LIF LIF MAPRE3 MAPRE3 LOX LOX PPP3CA PPP3CA NFATC4 NFATC4 ZNF593 ZNF593 CAV1 CAV1 NEK2 NEK2 ITGB1BP1 ITGB1BP1 JUN JUN PTPRF PTPRF HES1 HES1 HABP4 HABP4 ABL1 ABL1 TTC36 TTC36 MYOCD MYOCD ENSUAMP00000010247 ENSUAMP00000010247 ADD2 ADD2 AMFR AMFR HEY2 HEY2 CLDN5 CLDN5 PHLDA2 PHLDA2 ENSUAMP00000010882 ENSUAMP00000010882 CCPG1 CCPG1 ENSUAMP00000010915 ENSUAMP00000010915 CBLB CBLB ENSUAMP00000010997 ENSUAMP00000010997 ENSUAMP00000011008 ENSUAMP00000011008 GATA1 GATA1 DNAJB2 DNAJB2 ENSUAMP00000011420 ENSUAMP00000011420 WFIKKN2 WFIKKN2 GNL3L GNL3L ENSUAMP00000011802 ENSUAMP00000011802 ENSUAMP00000011876 ENSUAMP00000011876 GSK3B GSK3B ENSUAMP00000012241 ENSUAMP00000012241 CDON CDON ENSUAMP00000012266 ENSUAMP00000012266 TGFB1 TGFB1 ENSUAMP00000012590 ENSUAMP00000012590 ENSUAMP00000012642 ENSUAMP00000012642 CPNE1 CPNE1 DDRGK1 DDRGK1 LARP6 LARP6 RALB RALB BAX BAX ZC4H2 ZC4H2 ENSUAMP00000013482 ENSUAMP00000013482 ENSUAMP00000013648 ENSUAMP00000013648 SIRT2 SIRT2 ENSUAMP00000013995 ENSUAMP00000013995 MDFI MDFI CAMK1 CAMK1 ENSUAMP00000014507 ENSUAMP00000014507 ENSUAMP00000014514 ENSUAMP00000014514 BTAF1 BTAF1 RB1 RB1 MARK3 MARK3 ZNF618 ZNF618 DAB2 DAB2 ENSUAMP00000015206 ENSUAMP00000015206 ENSUAMP00000015472 ENSUAMP00000015472 RIPOR2 RIPOR2 GMNN GMNN AKTIP AKTIP PARK7 PARK7 DHX9 DHX9 EPHB6 EPHB6 DVL1 DVL1 LRRK2 LRRK2 ENSUAMP00000016331 ENSUAMP00000016331 TNKS TNKS ENSUAMP00000016646 ENSUAMP00000016646 CRK CRK BAG2 BAG2 TGFBR1 TGFBR1 NES NES ANKRD33 ANKRD33 ENSUAMP00000017561 ENSUAMP00000017561 ATP2A3 ATP2A3 ENSUAMP00000017736 ENSUAMP00000017736 ENSUAMP00000017796 ENSUAMP00000017796 PLN PLN SPPL3 SPPL3 PBXIP1 PBXIP1 PYGO2 PYGO2 ADAM15 ADAM15 SMAD4 SMAD4 ENSUAMP00000018593 ENSUAMP00000018593 LRRC6 LRRC6 ROCK1 ROCK1 ENSUAMP00000018939 ENSUAMP00000018939 PINX1 PINX1 CTNNBIP1 CTNNBIP1 MITD1 MITD1 ENSUAMP00000019904 ENSUAMP00000019904 ENSUAMP00000020051 ENSUAMP00000020051 RACK1 RACK1 ENSUAMP00000020176 ENSUAMP00000020176 ADIPOQ ADIPOQ ACD ACD BLK BLK ENSUAMP00000020334 ENSUAMP00000020334 PLCL1 PLCL1 DHRS7B DHRS7B AGER AGER TFIP11 TFIP11 HFE HFE MMP8 MMP8 BMP2 BMP2 USP33 USP33 BAMBI BAMBI EIF3D EIF3D ENSUAMP00000022261 ENSUAMP00000022261 ENSUAMP00000022262 ENSUAMP00000022262 STK4 STK4 LHX2 LHX2 CTHRC1 CTHRC1 BCL3 BCL3 RIPK2 RIPK2 VTN VTN B2M B2M FMR1 FMR1 SKI SKI PIN1 PIN1 MAD2L2 MAD2L2 HAND1 HAND1 FBXW9 FBXW9 WFIKKN1 WFIKKN1 SPON1 SPON1 ENSUAMP00000025615 ENSUAMP00000025615 ENSUAMP00000025721 ENSUAMP00000025721 DTNBP1 DTNBP1 CRMP1 CRMP1 ENSUAMP00000025819 ENSUAMP00000025819 XIRP1 XIRP1 ERCC2 ERCC2 TCF7L2 TCF7L2 MFNG MFNG IDE IDE LRPAP1 LRPAP1 SMAD3 SMAD3 ZBTB7C ZBTB7C ENSUAMP00000026682 ENSUAMP00000026682 ENSUAMP00000026963 ENSUAMP00000026963 ZFP90 ZFP90 RIPOR3 RIPOR3 ARHGEF7 ARHGEF7 LRP1 LRP1 TMC8 TMC8 FBXW7 FBXW7 SMO SMO WAPL WAPL HEY1 HEY1 DERL1 DERL1 GEMIN2 GEMIN2 CDKN1A CDKN1A CTSZ CTSZ UBASH3B UBASH3B GATA3 GATA3 BMP4 BMP4 ZBTB7A ZBTB7A USP9X USP9X PARP9 PARP9 DTX3L DTX3L SIN3A SIN3A SMARCD3 SMARCD3 ENSUAMP00000029521 ENSUAMP00000029521 CDK5 CDK5 NUCKS1 NUCKS1 DACT1 DACT1 RFNG RFNG CDK9 CDK9 IFIT1 IFIT1 CLIC2 CLIC2 ENSUAMP00000030035 ENSUAMP00000030035 IRF4 IRF4 SRC SRC SYMPK SYMPK TRAF6 TRAF6 ENSUAMP00000030547 ENSUAMP00000030547 APOE APOE NIBAN2 NIBAN2 MAPK3 MAPK3 NVL NVL EP300 EP300 ENSUAMP00000031985 ENSUAMP00000031985 ENSUAMP00000031986 ENSUAMP00000031986 ENSUAMP00000032358 ENSUAMP00000032358 ENSUAMP00000033333 ENSUAMP00000033333 ENSUAMP00000033583 ENSUAMP00000033583 DDIT3 DDIT3 LDLRAP1 LDLRAP1 TAF10 TAF10 ENSUAMP00000033824 ENSUAMP00000033824 ENSUAMP00000034195 ENSUAMP00000034195 GTF2B GTF2B FLOT1 FLOT1 E2F1 E2F1 GTF2F1 GTF2F1 MEPCE MEPCE SORL1 SORL1 SPTA1 SPTA1 STING1 STING1 SRI SRI DOT1L DOT1L ENSUAMP00000035777 ENSUAMP00000035777 ENSUAMP00000036238 ENSUAMP00000036238 EFHB EFHB ZMPSTE24 ZMPSTE24 RAPGEF2 RAPGEF2 ENSUAMP00000036326 ENSUAMP00000036326 GZMA GZMA ENSUAMP00000036809 ENSUAMP00000036809 ENSUAMP00000036811 ENSUAMP00000036811 ENSUAMP00000036853 ENSUAMP00000036853 ENSUAMP00000036855 ENSUAMP00000036855 MYOD1 MYOD1 ENSUAMP00000037329 ENSUAMP00000037329 ENSUAMP00000037519 ENSUAMP00000037519
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSUAMP00000000119C2H2-type domain-containing protein. (271 aa)
ENSUAMP00000000198Uncharacterized protein. (238 aa)
TRIM21Tripartite motif containing 21. (469 aa)
HEYLHes related family bHLH transcription factor with YRPW motif like. (328 aa)
ENSUAMP00000000316Homeobox domain-containing protein. (280 aa)
IL10Interleukin 10. (178 aa)
ENSUAMP00000000397Paired domain-containing protein. (216 aa)
ENSUAMP00000000603Uncharacterized protein. (69 aa)
MSX1Msh homeobox 1. (303 aa)
ENSUAMP00000000621Uncharacterized protein. (164 aa)
LFNGLFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase. (251 aa)
ENSUAMP00000000765Uncharacterized protein. (121 aa)
ENSUAMP00000001140DUF4939 domain-containing protein. (166 aa)
ENSUAMP00000001162DUF4939 domain-containing protein. (110 aa)
ENSUAMP00000001173DUF4939 domain-containing protein. (102 aa)
HIPK2Homeodomain interacting protein kinase 2. (1200 aa)
EGFEpidermal growth factor. (979 aa)
ENSUAMP00000001632S_100 domain-containing protein; Belongs to the S-100 family. (97 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
ENSUAMP00000001690Thioredoxin; Belongs to the thioredoxin family. (105 aa)
EDF1Endothelial differentiation related factor 1. (149 aa)
RSF1Remodeling and spacing factor 1. (1245 aa)
ENSUAMP00000002126zf-RING_14 domain-containing protein. (110 aa)
ENSUAMP00000002297Eph LBD domain-containing protein. (286 aa)
ZNF304Zinc finger protein 304. (617 aa)
ENSUAMP00000003003Plexin_cytopl domain-containing protein. (490 aa)
ENSUAMP00000003383Uncharacterized protein. (57 aa)
PLAURPlasminogen activator, urokinase receptor. (332 aa)
ENSUAMP00000003703DSPc domain-containing protein. (81 aa)
SNAPINSNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa)
ENSUAMP00000004097Uncharacterized protein. (245 aa)
TRIM28Tripartite motif containing 28. (832 aa)
ENSUAMP00000004664Rho-GAP domain-containing protein. (280 aa)
MED25Mediator complex subunit 25. (795 aa)
TRIB3Tribbles pseudokinase 3. (363 aa)
ENSUAMP00000005048Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (241 aa)
TEX14Testis expressed 14, intercellular bridge forming factor. (1425 aa)
ENSUAMP00000006064Uncharacterized protein. (80 aa)
NCBP1Nuclear cap binding protein subunit 1. (790 aa)
ENSUAMP00000006350Uncharacterized protein. (85 aa)
TFAP4Transcription factor AP-4. (339 aa)
ENSUAMP00000006607Uncharacterized protein. (215 aa)
HIP1RHuntingtin interacting protein 1 related. (1077 aa)
ENSUAMP00000006851RBR-type E3 ubiquitin transferase. (137 aa)
TTBK1Tau tubulin kinase 1. (1288 aa)
APPAmyloid beta precursor protein. (735 aa)
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (242 aa)
ENSUAMP00000007257Hist_deacetyl domain-containing protein. (252 aa)
HAND2Heart and neural crest derivatives expressed 2. (217 aa)
ENSUAMP00000007483DUF4939 domain-containing protein. (113 aa)
PON1Paraoxonase 1. (355 aa)
LIFLIF interleukin 6 family cytokine. (202 aa)
MAPRE3Microtubule associated protein RP/EB family member 3. (281 aa)
LOXLysyl oxidase. (414 aa)
PPP3CASerine/threonine-protein phosphatase. (317 aa)
NFATC4Nuclear factor of activated T cells 4. (911 aa)
ZNF593Zinc finger protein 593. (134 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
NEK2NIMA related kinase 2. (444 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (199 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa)
PTPRFProtein tyrosine phosphatase receptor type F. (1897 aa)
HES1Hes family bHLH transcription factor 1. (259 aa)
HABP4Hyaluronan binding protein 4. (408 aa)
ABL1Tyrosine-protein kinase. (1138 aa)
TTC36Tetratricopeptide repeat domain 36. (189 aa)
MYOCDMyocardin. (870 aa)
ENSUAMP00000010247Uncharacterized protein. (234 aa)
ADD2Adducin 2. (710 aa)
AMFRAutocrine motility factor receptor. (620 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
PHLDA2Pleckstrin homology like domain family A member 2. (131 aa)
ENSUAMP00000010882Uncharacterized protein. (543 aa)
CCPG1Cell cycle progression 1. (791 aa)
ENSUAMP00000010915Nefa_Nip30_N domain-containing protein. (95 aa)
CBLBCbl proto-oncogene B. (717 aa)
ENSUAMP00000010997TPR_REGION domain-containing protein. (150 aa)
ENSUAMP00000011008Uncharacterized protein. (538 aa)
GATA1GATA binding protein 1. (413 aa)
DNAJB2DnaJ heat shock protein family (Hsp40) member B2. (333 aa)
ENSUAMP0000001142060S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (428 aa)
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2. (573 aa)
GNL3LG protein nucleolar 3 like. (530 aa)
ENSUAMP00000011802Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1116 aa)
ENSUAMP00000011876ERCC4 domain-containing protein. (277 aa)
GSK3BGlycogen synthase kinase 3 beta. (335 aa)
ENSUAMP00000012241zf-RING_14 domain-containing protein. (109 aa)
CDONCell adhesion associated, oncogene regulated. (1021 aa)
ENSUAMP00000012266CTNNB1_binding domain-containing protein. (162 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
ENSUAMP00000012590Uncharacterized protein. (206 aa)
ENSUAMP00000012642Integrin_alpha2 domain-containing protein. (261 aa)
CPNE1Copine 1. (596 aa)
DDRGK1DDRGK domain containing 1. (344 aa)
LARP6La ribonucleoprotein domain family member 6. (496 aa)
RALBRAS like proto-oncogene B. (206 aa)
BAXBCL2 associated X, apoptosis regulator. (205 aa)
ZC4H2Zinc finger C4H2-type containing. (211 aa)
ENSUAMP00000013482Uncharacterized protein. (91 aa)
ENSUAMP00000013648Uncharacterized protein. (352 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (426 aa)
ENSUAMP00000013995Uncharacterized protein. (239 aa)
MDFIMyoD family inhibitor. (246 aa)
CAMK1Calcium/calmodulin dependent protein kinase I; Belongs to the protein kinase superfamily. (370 aa)
ENSUAMP00000014507RING-type domain-containing protein. (245 aa)
ENSUAMP00000014514RNF220 domain-containing protein. (104 aa)
BTAF1B-TFIID TATA-box binding protein associated factor 1. (1628 aa)
RB1RB transcriptional corepressor 1. (870 aa)
MARK3Non-specific serine/threonine protein kinase. (753 aa)
ZNF618Zinc finger protein 618. (944 aa)
DAB2DAB adaptor protein 2. (763 aa)
ENSUAMP00000015206Uncharacterized protein. (392 aa)
ENSUAMP00000015472Uncharacterized protein. (104 aa)
RIPOR2PL48 domain-containing protein. (1063 aa)
GMNNGeminin DNA replication inhibitor. (210 aa)
AKTIPAKT interacting protein. (292 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
DHX9DExH-box helicase 9. (1276 aa)
EPHB6EPH receptor B6. (1012 aa)
DVL1Dishevelled segment polarity protein 1. (700 aa)
LRRK2Leucine rich repeat kinase 2. (1967 aa)
ENSUAMP00000016331Ubiquitin-like domain-containing protein. (153 aa)
TNKSPoly [ADP-ribose] polymerase. (908 aa)
ENSUAMP00000016646Uncharacterized protein. (167 aa)
CRKCRK proto-oncogene, adaptor protein. (204 aa)
BAG2BCL2 associated athanogene 2. (197 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (501 aa)
NESNestin; Belongs to the intermediate filament family. (1793 aa)
ANKRD33Ankyrin repeat domain 33. (373 aa)
ENSUAMP00000017561Uncharacterized protein. (285 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (982 aa)
ENSUAMP00000017736Cation_ATPase_N domain-containing protein. (54 aa)
ENSUAMP00000017796N_BRCA1_IG domain-containing protein. (178 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
SPPL3Signal peptide peptidase like 3. (347 aa)
PBXIP1PBX homeobox interacting protein 1. (707 aa)
PYGO2Pygopus family PHD finger 2. (369 aa)
ADAM15ADAM metallopeptidase domain 15. (832 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
ENSUAMP00000018593eIF3_N domain-containing protein; Belongs to the eIF-3 subunit E family. (75 aa)
LRRC6Leucine rich repeat containing 6. (465 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1365 aa)
ENSUAMP00000018939Uncharacterized protein; Belongs to the ATP:guanido phosphotransferase family. (417 aa)
PINX1PIN2 (TERF1) interacting telomerase inhibitor 1. (318 aa)
CTNNBIP1Catenin beta interacting protein 1. (70 aa)
MITD1Microtubule interacting and trafficking domain containing 1. (235 aa)
ENSUAMP00000019904Uncharacterized protein. (199 aa)
ENSUAMP00000020051Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (445 aa)
RACK1Receptor for activated C kinase 1. (374 aa)
ENSUAMP00000020176S_100 domain-containing protein; Belongs to the S-100 family. (91 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (244 aa)
ACDACD shelterin complex subunit and telomerase recruitment factor. (452 aa)
BLKTyrosine-protein kinase. (500 aa)
ENSUAMP00000020334Uncharacterized protein. (95 aa)
PLCL1Phosphoinositide phospholipase C. (997 aa)
DHRS7BDehydrogenase/reductase 7B; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (324 aa)
AGERAdvanced glycosylation end-product specific receptor. (410 aa)
TFIP11Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...] (777 aa)
HFEHomeostatic iron regulator; Belongs to the MHC class I family. (355 aa)
MMP8Matrix metallopeptidase 8. (477 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
USP33Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (917 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa)
EIF3DEukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, a complex required for several steps in the initiation of protein synthesis of a specialized repertoire of mRNAs. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl- tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required [...] (546 aa)
ENSUAMP00000022261Uncharacterized protein. (123 aa)
ENSUAMP00000022262annotation not available (123 aa)
STK4Serine/threonine kinase 4. (487 aa)
LHX2LIM homeobox 2. (392 aa)
CTHRC1Collagen triple helix repeat containing 1. (277 aa)
BCL3BCL3 transcription coactivator. (424 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (536 aa)
VTNSMB domain-containing protein. (415 aa)
B2MBeta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (118 aa)
FMR1Fragile X mental retardation 1. (621 aa)
SKISKI proto-oncogene. (704 aa)
PIN1Peptidyl-prolyl cis-trans isomerase. (163 aa)
MAD2L2Mitotic arrest deficient 2 like 2. (211 aa)
HAND1Heart and neural crest derivatives expressed 1. (218 aa)
FBXW9F-box and WD repeat domain containing 9. (478 aa)
WFIKKN1WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1. (548 aa)
SPON1Spondin 1. (665 aa)
ENSUAMP00000025615Uncharacterized protein. (299 aa)
ENSUAMP00000025721Uncharacterized protein. (113 aa)
DTNBP1Dystrobrevin binding protein 1. (322 aa)
CRMP1Collapsin response mediator protein 1. (553 aa)
ENSUAMP00000025819Thioredoxin domain-containing protein. (103 aa)
XIRP1Xin actin binding repeat containing 1. (1846 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (759 aa)
TCF7L2Transcription factor 7 like 2. (524 aa)
MFNGBeta-1,3-N-acetylglucosaminyltransferase. (321 aa)
IDEInsulin degrading enzyme; Belongs to the peptidase M16 family. (1020 aa)
LRPAP1LDL receptor related protein associated protein 1. (367 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
ZBTB7CZinc finger and BTB domain containing 7C. (621 aa)
ENSUAMP00000026682Uncharacterized protein. (389 aa)
ENSUAMP00000026963Protein kinase domain-containing protein. (93 aa)
ZFP90ZFP90 zinc finger protein. (615 aa)
RIPOR3RIPOR family member 3. (935 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (782 aa)
LRP1LDL receptor related protein 1. (4548 aa)
TMC8Transmembrane channel-like protein. (723 aa)
FBXW7F-box and WD repeat domain containing 7. (627 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (788 aa)
WAPLWAPL cohesin release factor. (1103 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
DERL1Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (251 aa)
GEMIN2Gem nuclear organelle associated protein 2. (271 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (164 aa)
CTSZCathepsin Z; Belongs to the peptidase C1 family. (305 aa)
UBASH3BUbiquitin associated and SH3 domain containing B. (603 aa)
GATA3GATA binding protein 3. (444 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
ZBTB7AZinc finger and BTB domain containing 7A. (529 aa)
USP9XUbiquitin specific peptidase 9 X-linked; Belongs to the peptidase C19 family. (2153 aa)
PARP9Poly(ADP-ribose) polymerase family member 9. (827 aa)
DTX3LDeltex E3 ubiquitin ligase 3L. (688 aa)
SIN3ASIN3 transcription regulator family member A. (1275 aa)
SMARCD3SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (483 aa)
ENSUAMP00000029521Uncharacterized protein. (193 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
NUCKS1Nuclear casein kinase and cyclin dependent kinase substrate 1. (243 aa)
DACT1Dishevelled binding antagonist of beta catenin 1. (827 aa)
RFNGRFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase. (319 aa)
CDK9Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa)
IFIT1Interferon induced protein with tetratricopeptide repeats 1. (488 aa)
CLIC2Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (210 aa)
ENSUAMP00000030035Uncharacterized protein. (48 aa)
IRF4Interferon regulatory factor 4. (451 aa)
SRCTyrosine-protein kinase. (557 aa)
SYMPKSymplekin. (1277 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
ENSUAMP00000030547Uncharacterized protein. (268 aa)
APOEApolipoprotein E. (323 aa)
NIBAN2Niban apoptosis regulator 2. (736 aa)
MAPK3Mitogen-activated protein kinase. (354 aa)
NVLNuclear VCP like. (854 aa)
EP300E1A binding protein p300. (2399 aa)
ENSUAMP00000031985Uncharacterized protein. (493 aa)
ENSUAMP00000031986Uncharacterized protein. (575 aa)
ENSUAMP00000032358Thioredoxin domain-containing protein. (104 aa)
ENSUAMP00000033333Uncharacterized protein. (2171 aa)
ENSUAMP00000033583Uncharacterized protein. (659 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa)
LDLRAP1Low density lipoprotein receptor adaptor protein 1. (309 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (199 aa)
ENSUAMP00000033824CDT1 domain-containing protein. (780 aa)
ENSUAMP00000034195Uncharacterized protein. (1577 aa)
GTF2BGeneral transcription factor IIB. (316 aa)
FLOT1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa)
E2F1E2F transcription factor 1. (400 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (538 aa)
MEPCEMethylphosphate capping enzyme. (653 aa)
SORL1Sortilin related receptor 1. (2210 aa)
SPTA1Spectrin alpha, erythrocytic 1. (2420 aa)
STING1Transmembrane protein 173. (392 aa)
SRISorcin. (198 aa)
DOT1LHistone-lysine N-methyltransferase, H3 lysine-79 specific. (1520 aa)
ENSUAMP00000035777HMG box domain-containing protein. (191 aa)
ENSUAMP00000036238Uncharacterized protein. (214 aa)
EFHBEF-hand domain family member B. (596 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1516 aa)
ENSUAMP00000036326Uncharacterized protein. (630 aa)
GZMAGranzyme A; Belongs to the peptidase S1 family. (258 aa)
ENSUAMP00000036809Uncharacterized protein. (68 aa)
ENSUAMP00000036811Uncharacterized protein. (669 aa)
ENSUAMP00000036853Uncharacterized protein. (1459 aa)
ENSUAMP00000036855PWWP domain-containing protein. (570 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa)
ENSUAMP00000037329Calponin-homology (CH) domain-containing protein. (205 aa)
ENSUAMP00000037519Pex14_N domain-containing protein. (165 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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