28 items (Ursus americanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HEY1	Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
	COMP	Cartilage oligomeric matrix protein. (756 aa)
	NOTCH1	Notch receptor 1. (2547 aa)
	MRTFB	SAP domain-containing protein. (974 aa)
	NPNT	Nephronectin. (462 aa)
	ENG	Endoglin. (650 aa)
	MEF2C	Myocyte enhancer factor 2C. (483 aa)
	ENSUAMP00000029003	Uncharacterized protein. (105 aa)
	BMP4	Bone morphogenetic protein 4. (409 aa)
	SOX9	SRY-box transcription factor 9. (484 aa)
	MECP2	Methyl-CpG binding protein 2. (440 aa)
	SRF	Serum response factor. (507 aa)
	ENSUAMP00000017830	Uncharacterized protein. (157 aa)
	TMEM204	Transmembrane protein 204. (226 aa)
	RAMP2	Receptor activity modifying protein 2. (100 aa)
	FOXF1	Forkhead box F1. (379 aa)
	APLNR	Apelin receptor; Belongs to the G-protein coupled receptor 1 family. (380 aa)
	HEY2	Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
	MYOCD	Myocardin. (870 aa)
	HES1	Hes family bHLH transcription factor 1. (259 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
	NFATC4	Nuclear factor of activated T cells 4. (911 aa)
	MRTFA	Myocardin related transcription factor A. (926 aa)
	ENSUAMP00000004728	G_PROTEIN_RECEP_F1_2 domain-containing protein. (155 aa)
	ENSUAMP00000004725	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (253 aa)
	TBX2	T-box transcription factor 2. (697 aa)
	ENSUAMP00000000600	Uncharacterized protein. (130 aa)
	HEYL	Hes related family bHLH transcription factor with YRPW motif like. (328 aa)

Your Current Organism:

Ursus americanus

NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP4	ENSUAMP00000000600	ENSUAMP00000028868	ENSUAMP00000000600	Bone morphogenetic protein 4.	Uncharacterized protein.	0.428
BMP4	ENSUAMP00000017830	ENSUAMP00000028868	ENSUAMP00000017830	Bone morphogenetic protein 4.	Uncharacterized protein.	0.428
BMP4	FGF10	ENSUAMP00000028868	ENSUAMP00000008288	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.758
BMP4	FOXF1	ENSUAMP00000028868	ENSUAMP00000016230	Bone morphogenetic protein 4.	Forkhead box F1.	0.500
BMP4	MEF2C	ENSUAMP00000028868	ENSUAMP00000029640	Bone morphogenetic protein 4.	Myocyte enhancer factor 2C.	0.418
BMP4	NOTCH1	ENSUAMP00000028868	ENSUAMP00000034225	Bone morphogenetic protein 4.	Notch receptor 1.	0.426
BMP4	SOX9	ENSUAMP00000028868	ENSUAMP00000026554	Bone morphogenetic protein 4.	SRY-box transcription factor 9.	0.606
COMP	SOX9	ENSUAMP00000036538	ENSUAMP00000026554	Cartilage oligomeric matrix protein.	SRY-box transcription factor 9.	0.545
ENSUAMP00000000600	BMP4	ENSUAMP00000000600	ENSUAMP00000028868	Uncharacterized protein.	Bone morphogenetic protein 4.	0.428
ENSUAMP00000000600	ENSUAMP00000017830	ENSUAMP00000000600	ENSUAMP00000017830	Uncharacterized protein.	Uncharacterized protein.	0.671
ENSUAMP00000017830	BMP4	ENSUAMP00000017830	ENSUAMP00000028868	Uncharacterized protein.	Bone morphogenetic protein 4.	0.428
ENSUAMP00000017830	ENSUAMP00000000600	ENSUAMP00000017830	ENSUAMP00000000600	Uncharacterized protein.	Uncharacterized protein.	0.671
ENSUAMP00000029003	MRTFB	ENSUAMP00000029003	ENSUAMP00000034175	Uncharacterized protein.	SAP domain-containing protein.	0.846
ENSUAMP00000029003	SRF	ENSUAMP00000029003	ENSUAMP00000020039	Uncharacterized protein.	Serum response factor.	0.872
FGF10	BMP4	ENSUAMP00000008288	ENSUAMP00000028868	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Bone morphogenetic protein 4.	0.758
FGF10	SOX9	ENSUAMP00000008288	ENSUAMP00000026554	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	SRY-box transcription factor 9.	0.547
FOXF1	BMP4	ENSUAMP00000016230	ENSUAMP00000028868	Forkhead box F1.	Bone morphogenetic protein 4.	0.500
FOXF1	MYOCD	ENSUAMP00000016230	ENSUAMP00000009957	Forkhead box F1.	Myocardin.	0.585
FOXF1	SOX9	ENSUAMP00000016230	ENSUAMP00000026554	Forkhead box F1.	SRY-box transcription factor 9.	0.430
FOXF1	SRF	ENSUAMP00000016230	ENSUAMP00000020039	Forkhead box F1.	Serum response factor.	0.510