STRINGSTRING
CBY1 CBY1 CRYZ CRYZ UPB1 UPB1 ENSUAMP00000013328 ENSUAMP00000013328 ACACB ACACB ENSUAMP00000011933 ENSUAMP00000011933 SHMT1 SHMT1 ENSUAMP00000001906 ENSUAMP00000001906 ENSUAMP00000003272 ENSUAMP00000003272 USP16 USP16 ENSUAMP00000005111 ENSUAMP00000005111 AQP5 AQP5 ENSUAMP00000006423 ENSUAMP00000006423 ENSUAMP00000008156 ENSUAMP00000008156 ENSUAMP00000008512 ENSUAMP00000008512 SAMHD1 SAMHD1 APIP APIP ENSUAMP00000011307 ENSUAMP00000011307 ENSUAMP00000011425 ENSUAMP00000011425 ENSUAMP00000011619 ENSUAMP00000011619 ENSUAMP00000011922 ENSUAMP00000011922 MCOLN1 MCOLN1 GNMT GNMT B2M B2M CBR4 CBR4 VASP VASP AQP4 AQP4 SHMT2 SHMT2 TK1 TK1 TDO2 TDO2 ENSUAMP00000020428 ENSUAMP00000020428 MIP MIP ENSUAMP00000028824 ENSUAMP00000028824 PKD2 PKD2 HSD17B10 HSD17B10 ENSUAMP00000031850 ENSUAMP00000031850 ENSUAMP00000031851 ENSUAMP00000031851 TRPM2 TRPM2 ATP5IF1 ATP5IF1 KCNJ2 KCNJ2 ACOT13 ACOT13 APPL2 APPL2 ENSUAMP00000036260 ENSUAMP00000036260 CRTC1 CRTC1 PKD2L1 PKD2L1 TRPV1 TRPV1 ALDH1A3 ALDH1A3 TRPA1 TRPA1 SSBP1 SSBP1 AQP10 AQP10 ENSUAMP00000017155 ENSUAMP00000017155 THG1L THG1L ME1 ME1 MAT1A MAT1A CRTC3 CRTC3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CBY1Chibby family member 1, beta catenin antagonist. (127 aa)
CRYZCrystallin zeta. (330 aa)
UPB1Beta-ureidopropionase 1. (384 aa)
ENSUAMP00000013328Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (237 aa)
ACACBAcetyl-CoA carboxylase beta. (2045 aa)
ENSUAMP00000011933WH1 domain-containing protein. (160 aa)
SHMT1Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (484 aa)
ENSUAMP00000001906Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (270 aa)
ENSUAMP00000003272SHMT domain-containing protein. (59 aa)
USP16Ubiquitin carboxyl-terminal hydrolase 16; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. (827 aa)
ENSUAMP00000005111Aldedh domain-containing protein. (208 aa)
AQP5Aquaporin 5; Belongs to the MIP/aquaporin (TC 1.A.8) family. (265 aa)
ENSUAMP00000006423Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (89 aa)
ENSUAMP00000008156Uncharacterized protein. (93 aa)
ENSUAMP00000008512Biotin carboxylation domain-containing protein. (206 aa)
SAMHD1SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1. (597 aa)
APIPAPAF1 interacting protein. (199 aa)
ENSUAMP00000011307Uncharacterized protein. (1315 aa)
ENSUAMP00000011425Malic domain-containing protein. (254 aa)
ENSUAMP00000011619Malic_M domain-containing protein. (256 aa)
ENSUAMP00000011922VASP_tetra domain-containing protein. (53 aa)
MCOLN1Mucolipin 1. (595 aa)
GNMTGlycine N-methyltransferase. (295 aa)
B2MBeta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (118 aa)
CBR4Carbonyl reductase 4. (237 aa)
VASPVasodilator stimulated phosphoprotein. (359 aa)
AQP4Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family. (323 aa)
SHMT2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (504 aa)
TK1Thymidine kinase. (239 aa)
TDO2Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (406 aa)
ENSUAMP00000020428Uncharacterized protein. (511 aa)
MIPMajor intrinsic protein of lens fiber; Belongs to the MIP/aquaporin (TC 1.A.8) family. (263 aa)
ENSUAMP00000028824LSDAT_euk domain-containing protein. (181 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (897 aa)
HSD17B10Hydroxysteroid 17-beta dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (261 aa)
ENSUAMP00000031850TORC_C domain-containing protein. (261 aa)
ENSUAMP00000031851TORC_N domain-containing protein. (145 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1488 aa)
ATP5IF1ATP synthase inhibitory factor subunit 1. (103 aa)
KCNJ2Potassium voltage-gated channel subfamily J member 2. (427 aa)
ACOT13Acyl-CoA thioesterase 13. (143 aa)
APPL2Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (652 aa)
ENSUAMP00000036260Uncharacterized protein. (1033 aa)
CRTC1CREB regulated transcription coactivator 1. (613 aa)
PKD2L1Polycystin 2 like 1, transient receptor potential cation channel. (807 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (851 aa)
ALDH1A3Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family. (512 aa)
TRPA1Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1068 aa)
SSBP1Single stranded DNA binding protein 1. (143 aa)
AQP10Aquaporin 10; Belongs to the MIP/aquaporin (TC 1.A.8) family. (301 aa)
ENSUAMP00000017155Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (518 aa)
THG1LtRNA(His) guanylyltransferase; Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. (298 aa)
ME1Malic enzyme. (580 aa)
MAT1AS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (396 aa)
CRTC3CREB regulated transcription coactivator 3. (582 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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