STRINGSTRING
ENSUAMP00000035527 ENSUAMP00000035527 CES5A CES5A ENSUAMP00000035567 ENSUAMP00000035567 ENSUAMP00000035568 ENSUAMP00000035568 ENSUAMP00000035580 ENSUAMP00000035580 ABHD6 ABHD6 PNPLA3 PNPLA3 ACHE ACHE ABHD10 ABHD10 ABHD16B ABHD16B PGLS PGLS ENSUAMP00000001793 ENSUAMP00000001793 ENSUAMP00000001835 ENSUAMP00000001835 TM7SF3 TM7SF3 ENSUAMP00000002388 ENSUAMP00000002388 ENSUAMP00000002465 ENSUAMP00000002465 ENSUAMP00000003362 ENSUAMP00000003362 PPME1 PPME1 FAAH FAAH ENSUAMP00000004111 ENSUAMP00000004111 DDHD2 DDHD2 ENSUAMP00000004579 ENSUAMP00000004579 LARS2 LARS2 ACOT7 ACOT7 GDPD1 GDPD1 ENSUAMP00000005012 ENSUAMP00000005012 PAFAH1B2 PAFAH1B2 PLAAT5 PLAAT5 PLAAT3 PLAAT3 ENSUAMP00000005514 ENSUAMP00000005514 ALDH1B1 ALDH1B1 PROCA1 PROCA1 PNPLA4 PNPLA4 ENSUAMP00000006010 ENSUAMP00000006010 ENSUAMP00000006085 ENSUAMP00000006085 ENSUAMP00000006194 ENSUAMP00000006194 PLAAT4 PLAAT4 LIPF LIPF ENSUAMP00000006820 ENSUAMP00000006820 PLAAT1 PLAAT1 PLA2G12B PLA2G12B PON2 PON2 PON3 PON3 PON1 PON1 CES2 CES2 LIPC LIPC ABHD1 ABHD1 ENSUAMP00000008067 ENSUAMP00000008067 AARS1 AARS1 ENSUAMP00000009753 ENSUAMP00000009753 PLA2G10 PLA2G10 FAM78A FAM78A LIPG LIPG LYPLA2 LYPLA2 LIPH LIPH ENSUAMP00000011405 ENSUAMP00000011405 ENSUAMP00000011947 ENSUAMP00000011947 ENSUAMP00000011951 ENSUAMP00000011951 CA2 CA2 PLA1A PLA1A PLA2G4A PLA2G4A ENSUAMP00000012232 ENSUAMP00000012232 PLA2G3 PLA2G3 APMAP APMAP PLA2G2E PLA2G2E MRPL58 MRPL58 LIPE LIPE PAFAH1B3 PAFAH1B3 PLA2G7 PLA2G7 ABHD8 ABHD8 PLA2G5 PLA2G5 PLA2G2D PLA2G2D PNPLA5 PNPLA5 PLA2G2F PLA2G2F PLA2G2C PLA2G2C VARS1 VARS1 ABHD16A ABHD16A PNLIPRP3 PNLIPRP3 PNLIP PNLIP PNLIPRP1 PNLIPRP1 PNLIPRP2 PNLIPRP2 LYPLAL1 LYPLAL1 ENSUAMP00000016236 ENSUAMP00000016236 ENSUAMP00000016237 ENSUAMP00000016237 ENSUAMP00000016262 ENSUAMP00000016262 ENSUAMP00000016299 ENSUAMP00000016299 ENSUAMP00000016481 ENSUAMP00000016481 ENSUAMP00000016577 ENSUAMP00000016577 ACOT11 ACOT11 ABHD3 ABHD3 IARS1 IARS1 ENSUAMP00000018685 ENSUAMP00000018685 ENSUAMP00000019169 ENSUAMP00000019169 BPHL BPHL PGAP6 PGAP6 PLA2G15 PLA2G15 PGAP1 PGAP1 ENSUAMP00000020855 ENSUAMP00000020855 ABHD11 ABHD11 NCEH1 NCEH1 ESD ESD LPL LPL DEPDC1 DEPDC1 RPE65 RPE65 TNFAIP6 TNFAIP6 DTD2 DTD2 DAGLA DAGLA LYPLA1 LYPLA1 PNPLA6 PNPLA6 PLA2G1B PLA2G1B ENSUAMP00000024768 ENSUAMP00000024768 ENSUAMP00000025194 ENSUAMP00000025194 GDE1 GDE1 LARS1 LARS1 PNPLA8 PNPLA8 PLA2G4F PLA2G4F PLA2G4D PLA2G4D ENSUAMP00000026182 ENSUAMP00000026182 LCAT LCAT IARS2 IARS2 ENSUAMP00000027756 ENSUAMP00000027756 MGLL MGLL ENSUAMP00000027887 ENSUAMP00000027887 ACOT12 ACOT12 PNPLA2 PNPLA2 ENSUAMP00000028672 ENSUAMP00000028672 ABHD15 ABHD15 ENSUAMP00000029152 ENSUAMP00000029152 ABHD4 ABHD4 PLA2G4E PLA2G4E DAGLB DAGLB PTRH1 PTRH1 TARS2 TARS2 H6PD H6PD ENSUAMP00000031478 ENSUAMP00000031478 GDPD3 GDPD3 SMIM26 SMIM26 NOTUM NOTUM CEL CEL PLA2G12A PLA2G12A PNPLA1 PNPLA1 ENSUAMP00000032602 ENSUAMP00000032602 PAFAH2 PAFAH2 RGN RGN VARS2 VARS2 BCHE BCHE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSUAMP00000035527Uncharacterized protein. (192 aa)
CES5ACarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (552 aa)
ENSUAMP00000035567Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (566 aa)
ENSUAMP00000035568Uncharacterized protein. (99 aa)
ENSUAMP00000035580Lipase domain-containing protein. (153 aa)
ABHD6Abhydrolase domain containing 6. (337 aa)
PNPLA3Patatin like phospholipase domain containing 3. (433 aa)
ACHECarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (689 aa)
ABHD10Abhydrolase domain containing 10. (266 aa)
ABHD16BAbhydrolase domain containing 16B. (470 aa)
PGLS6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (321 aa)
ENSUAMP00000001793HotDog ACOT-type domain-containing protein. (187 aa)
ENSUAMP00000001835Aldedh domain-containing protein. (222 aa)
TM7SF3Transmembrane 7 superfamily member 3. (570 aa)
ENSUAMP00000002388Uncharacterized protein. (84 aa)
ENSUAMP00000002465Uncharacterized protein. (476 aa)
ENSUAMP00000003362Uncharacterized protein. (118 aa)
PPME1Protein phosphatase methylesterase 1; Demethylates proteins that have been reversibly carboxymethylated. (324 aa)
FAAHFatty acid amide hydrolase. (579 aa)
ENSUAMP00000004111Amidase domain-containing protein. (608 aa)
DDHD2DDHD domain containing 2. (748 aa)
ENSUAMP00000004579Abhydrolase_3 domain-containing protein. (224 aa)
LARS2Leucyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (903 aa)
ACOT7Acyl-CoA thioesterase 7. (357 aa)
GDPD1Glycerophosphodiester phosphodiesterase domain containing 1. (200 aa)
ENSUAMP00000005012Uncharacterized protein. (59 aa)
PAFAH1B2Platelet activating factor acetylhydrolase 1b catalytic subunit 2. (229 aa)
PLAAT5Phospholipase A and acyltransferase 5. (269 aa)
PLAAT3Phospholipase A and acyltransferase 3. (189 aa)
ENSUAMP00000005514LRAT domain-containing protein. (143 aa)
ALDH1B1Aldehyde dehydrogenase 1 family member B1. (491 aa)
PROCA1Protein interacting with cyclin A1. (379 aa)
PNPLA4Patatin like phospholipase domain containing 4. (253 aa)
ENSUAMP00000006010AA_TRNA_LIGASE_II_ALA domain-containing protein. (568 aa)
ENSUAMP00000006085Uncharacterized protein. (64 aa)
ENSUAMP00000006194ANK_REP_REGION domain-containing protein. (259 aa)
PLAAT4Phospholipase A and acyltransferase 4. (148 aa)
LIPFLipase; Belongs to the AB hydrolase superfamily. Lipase family. (398 aa)
ENSUAMP00000006820Lipase_GDSL domain-containing protein. (326 aa)
PLAAT1Phospholipase A and acyltransferase 1. (169 aa)
PLA2G12BPhospholipase A2 group XIIB. (117 aa)
PON2Paraoxonase 2. (354 aa)
PON3Paraoxonase 3. (354 aa)
PON1Paraoxonase 1. (355 aa)
CES2Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (559 aa)
LIPCLipase C, hepatic type. (498 aa)
ABHD1Abhydrolase domain containing 1. (374 aa)
ENSUAMP00000008067BAAT_C domain-containing protein. (197 aa)
AARS1Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family. (968 aa)
ENSUAMP00000009753Uncharacterized protein. (77 aa)
PLA2G10Phospholipase A(2). (157 aa)
FAM78AFamily with sequence similarity 78 member A. (283 aa)
LIPGLipase G, endothelial type. (494 aa)
LYPLA2Lysophospholipase 2. (307 aa)
LIPHLipase H. (396 aa)
ENSUAMP00000011405Uncharacterized protein. (482 aa)
ENSUAMP00000011947Uncharacterized protein. (190 aa)
ENSUAMP00000011951Uncharacterized protein. (175 aa)
CA2Carbonic anhydrase 2; Belongs to the alpha-carbonic anhydrase family. (251 aa)
PLA1APhospholipase A1 member A. (456 aa)
PLA2G4APhospholipase A2. (756 aa)
ENSUAMP00000012232Uncharacterized protein. (938 aa)
PLA2G3Phospholipase A2 group III. (508 aa)
APMAPAdipocyte plasma membrane associated protein. (381 aa)
PLA2G2EPhospholipase A(2). (142 aa)
MRPL58Mitochondrial ribosomal protein L58. (206 aa)
LIPELipase E, hormone sensitive type. (805 aa)
PAFAH1B3Platelet activating factor acetylhydrolase 1b catalytic subunit 3. (231 aa)
PLA2G7Platelet-activating factor acetylhydrolase. (405 aa)
ABHD8Abhydrolase domain containing 8. (432 aa)
PLA2G5Phospholipase A(2). (137 aa)
PLA2G2DPhospholipase A(2). (159 aa)
PNPLA5Patatin like phospholipase domain containing 5. (462 aa)
PLA2G2FPhospholipase A(2). (199 aa)
PLA2G2CPhospholipase A(2). (144 aa)
VARS1Valyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (1263 aa)
ABHD16AAbhydrolase domain containing 16A. (558 aa)
PNLIPRP3Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (362 aa)
PNLIPTriacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (465 aa)
PNLIPRP1Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (467 aa)
PNLIPRP2Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (469 aa)
LYPLAL1Lysophospholipase like 1. (239 aa)
ENSUAMP00000016236Uncharacterized protein. (113 aa)
ENSUAMP00000016237Uncharacterized protein. (211 aa)
ENSUAMP00000016262Cyclic nucleotide-binding domain-containing protein. (259 aa)
ENSUAMP00000016299Uncharacterized protein. (200 aa)
ENSUAMP00000016481AA_TRNA_LIGASE_II_ALA domain-containing protein. (412 aa)
ENSUAMP00000016577Uncharacterized protein. (135 aa)
ACOT11Acyl-CoA thioesterase 11. (539 aa)
ABHD3Abhydrolase domain containing 3. (369 aa)
IARS1Isoleucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (1261 aa)
ENSUAMP00000018685Uncharacterized protein. (936 aa)
ENSUAMP00000019169Uncharacterized protein. (883 aa)
BPHLBiphenyl hydrolase like. (295 aa)
PGAP6Transmembrane protein 8A. (743 aa)
PLA2G15Phospholipase A2 group XV. (408 aa)
PGAP1GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI- anchored proteins from the endoplasmic reticulum to the Golgi. (922 aa)
ENSUAMP00000020855Uncharacterized protein. (512 aa)
ABHD11Abhydrolase domain containing 11. (313 aa)
NCEH1Neutral cholesterol ester hydrolase 1. (402 aa)
ESDS-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (292 aa)
LPLLipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (476 aa)
DEPDC1DEP domain containing 1. (811 aa)
RPE65Retinoid isomerohydrolase RPE65. (530 aa)
TNFAIP6TNF alpha induced protein 6. (277 aa)
DTD2D-aminoacyl-tRNA deacylase 2. (168 aa)
DAGLADiacylglycerol lipase alpha. (1038 aa)
LYPLA1Lysophospholipase 1. (230 aa)
PNPLA6Patatin like phospholipase domain containing 6. (1326 aa)
PLA2G1BPhospholipase A(2). (119 aa)
ENSUAMP00000024768AB hydrolase-1 domain-containing protein. (164 aa)
ENSUAMP00000025194tRNA_edit domain-containing protein. (172 aa)
GDE1Glycerophosphodiester phosphodiesterase 1. (331 aa)
LARS1Leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (1113 aa)
PNPLA8Patatin like phospholipase domain containing 8. (780 aa)
PLA2G4FPhospholipase A2. (837 aa)
PLA2G4DPhospholipase A2. (776 aa)
ENSUAMP00000026182Abhydrolase_3 domain-containing protein. (237 aa)
LCATLecithin-cholesterol acyltransferase. (440 aa)
IARS2Isoleucyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (1012 aa)
ENSUAMP00000027756D-aminoacyl-tRNA deacylase. (157 aa)
MGLLMonoglyceride lipase. (304 aa)
ENSUAMP00000027887Uncharacterized protein. (303 aa)
ACOT12Acyl-CoA thioesterase 12. (460 aa)
PNPLA2Patatin like phospholipase domain containing 2. (518 aa)
ENSUAMP00000028672Phospholipase A2. (765 aa)
ABHD15Abhydrolase domain containing 15. (464 aa)
ENSUAMP00000029152Thioredoxin domain-containing protein. (268 aa)
ABHD4Abhydrolase domain containing 4. (355 aa)
PLA2G4EPhospholipase A2. (822 aa)
DAGLBDiacylglycerol lipase beta. (671 aa)
PTRH1Peptidyl-tRNA hydrolase 1 homolog. (222 aa)
TARS2Threonyl-tRNA synthetase 2, mitochondrial. (613 aa)
H6PDHexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase. (804 aa)
ENSUAMP00000031478Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (221 aa)
GDPD3Glycerophosphodiester phosphodiesterase domain containing 3. (318 aa)
SMIM26Small integral membrane protein 26. (90 aa)
NOTUMNotum, palmitoleoyl-protein carboxylesterase. (498 aa)
CELCarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (599 aa)
PLA2G12APhospholipase A2 group XIIA. (190 aa)
PNPLA1Patatin like phospholipase domain containing 1. (522 aa)
ENSUAMP00000032602Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (72 aa)
PAFAH2Platelet activating factor acetylhydrolase 2. (323 aa)
RGNRegucalcin. (299 aa)
VARS2Valyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (1093 aa)
BCHECarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (607 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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