STRINGSTRING
BMPR1A BMPR1A NOG NOG ENSUAMP00000004725 ENSUAMP00000004725 ENSUAMP00000004728 ENSUAMP00000004728 ENSUAMP00000004918 ENSUAMP00000004918 PTCH1 PTCH1 HES1 HES1 NKX2-6 NKX2-6 TGFBR1 TGFBR1 BMPR2 BMPR2 HOXA2 HOXA2 ENSUAMP00000019144 ENSUAMP00000019144 ENSUAMP00000019152 ENSUAMP00000019152 EYA1 EYA1 ENSUAMP00000020431 ENSUAMP00000020431 SIX4 SIX4 GATA3 GATA3 BMP4 BMP4 ADGRF5 ADGRF5 EDN1 EDN1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
ENSUAMP00000004725G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (253 aa)
ENSUAMP00000004728G_PROTEIN_RECEP_F1_2 domain-containing protein. (155 aa)
ENSUAMP00000004918Homeobox domain-containing protein. (230 aa)
PTCH1Patched 1. (1453 aa)
HES1Hes family bHLH transcription factor 1. (259 aa)
NKX2-6NK2 homeobox 6. (268 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (501 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (857 aa)
HOXA2Homeobox A2. (374 aa)
ENSUAMP00000019144Plexin_cytopl domain-containing protein. (215 aa)
ENSUAMP00000019152Sema domain-containing protein. (489 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (515 aa)
ENSUAMP00000020431Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (76 aa)
SIX4SIX homeobox 4. (783 aa)
GATA3GATA binding protein 3. (444 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
ADGRF5Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. (1346 aa)
EDN1Endothelin 1. (202 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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