STRINGSTRING
TGFB1 TGFB1 SH2B1 SH2B1 NODAL NODAL DAB2 DAB2 ENSUAMP00000015435 ENSUAMP00000015435 ENSUAMP00000016756 ENSUAMP00000016756 BMP2 BMP2 TGFBR1 TGFBR1 NUP93 NUP93 BMP4 BMP4 ENSUAMP00000034691 ENSUAMP00000034691 BMPR1A BMPR1A BMPR2 BMPR2 SMAD4 SMAD4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
SH2B1SH2B adaptor protein 1. (760 aa)
NODALNodal growth differentiation factor. (348 aa)
DAB2DAB adaptor protein 2. (763 aa)
ENSUAMP00000015435Uncharacterized protein. (194 aa)
ENSUAMP00000016756Uncharacterized protein. (210 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (501 aa)
NUP93Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (819 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
ENSUAMP00000034691RRM domain-containing protein. (153 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (857 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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