STRINGSTRING
ENSUAMP00000033749 ENSUAMP00000033749 TMEM161A TMEM161A ETV5 ETV5 ENSUAMP00000000893 ENSUAMP00000000893 TP53 TP53 ENSUAMP00000001033 ENSUAMP00000001033 ENSUAMP00000001538 ENSUAMP00000001538 ENSUAMP00000001779 ENSUAMP00000001779 ENSUAMP00000002198 ENSUAMP00000002198 ENSUAMP00000002781 ENSUAMP00000002781 RAD52 RAD52 FOXO1 FOXO1 ZNF277 ZNF277 ENSUAMP00000004725 ENSUAMP00000004725 ENSUAMP00000004728 ENSUAMP00000004728 ATF4 ATF4 MGAT3 MGAT3 ENSUAMP00000004964 ENSUAMP00000004964 SETX SETX ENSUAMP00000005458 ENSUAMP00000005458 ANXA1 ANXA1 CAPN3 CAPN3 MAP3K5 MAP3K5 MELK MELK NFE2L2 NFE2L2 NET1 NET1 CAV1 CAV1 ENSUAMP00000008796 ENSUAMP00000008796 ENSUAMP00000008823 ENSUAMP00000008823 WNK3 WNK3 JUN JUN ANKZF1 ANKZF1 PIK3CA PIK3CA CAT CAT ABL1 ABL1 PRKD1 PRKD1 ENSUAMP00000010033 ENSUAMP00000010033 PRDX1 PRDX1 ATF2 ATF2 STK25 STK25 NCF1 NCF1 EPAS1 EPAS1 ENSUAMP00000010575 ENSUAMP00000010575 SOD1 SOD1 EIF2S1 EIF2S1 ENSUAMP00000011130 ENSUAMP00000011130 ENSUAMP00000011295 ENSUAMP00000011295 ENSUAMP00000011462 ENSUAMP00000011462 PRDX3 PRDX3 SELENOS SELENOS FOXO3 FOXO3 FOXO3B FOXO3B ANKRD2 ANKRD2 ENSUAMP00000012831 ENSUAMP00000012831 ARNT ARNT SOD3 SOD3 ROMO1 ROMO1 SLC4A11 SLC4A11 PJVK PJVK ENSUAMP00000013203 ENSUAMP00000013203 HDAC6 HDAC6 ZFP36L1 ZFP36L1 UCP1 UCP1 MAPK1 MAPK1 SIRT2 SIRT2 G6PD G6PD RNF112 RNF112 PINK1 PINK1 STOX1 STOX1 IMPACT IMPACT NR4A2 NR4A2 PRKAA2 PRKAA2 AIF1 AIF1 ERRFI1 ERRFI1 PARK7 PARK7 LRRK2 LRRK2 ENSUAMP00000033750 ENSUAMP00000033750 ENSUAMP00000016276 ENSUAMP00000016276 ENSUAMP00000016418 ENSUAMP00000016418 DDX3X DDX3X ENSUAMP00000016793 ENSUAMP00000016793 ENSUAMP00000016990 ENSUAMP00000016990 STK26 STK26 ZC3H12A ZC3H12A ENSUAMP00000018082 ENSUAMP00000018082 PARP1 PARP1 ENSUAMP00000018315 ENSUAMP00000018315 SLC2A4 SLC2A4 CCS CCS PDGFRA PDGFRA CYP1B1 CYP1B1 PRDX5 PRDX5 RIPK1 RIPK1 ENSUAMP00000019742 ENSUAMP00000019742 ARHGEF2 ARHGEF2 TP53INP1 TP53INP1 SMPD3 SMPD3 TRPA1 TRPA1 CASP3 CASP3 ENSUAMP00000020667 ENSUAMP00000020667 PTPRK PTPRK ENSUAMP00000021280 ENSUAMP00000021280 YBX3 YBX3 SIRT1 SIRT1 PYCR1 PYCR1 ENSUAMP00000021600 ENSUAMP00000021600 OSER1 OSER1 NFE2L1 NFE2L1 PDCD10 PDCD10 WNT16 WNT16 RCSD1 RCSD1 SIGMAR1 SIGMAR1 ENSUAMP00000022567 ENSUAMP00000022567 PLEKHA1 PLEKHA1 PNPT1 PNPT1 KEAP1 KEAP1 SLC7A11 SLC7A11 ATG5 ATG5 ENSUAMP00000024788 ENSUAMP00000024788 OXR1 OXR1 ENSUAMP00000025110 ENSUAMP00000025110 ENSUAMP00000025156 ENSUAMP00000025156 BDKRB2 BDKRB2 ZNF580 ZNF580 ENSUAMP00000026632 ENSUAMP00000026632 SLC12A6 SLC12A6 RELA RELA PPARGC1A PPARGC1A TNFAIP3 TNFAIP3 GSR GSR LRRC8E LRRC8E RPS3 RPS3 ENSUAMP00000027993 ENSUAMP00000027993 HTRA2 HTRA2 MAPK9 MAPK9 EZH2 EZH2 PLA2R1 PLA2R1 SPHK1 SPHK1 ENSUAMP00000029334 ENSUAMP00000029334 PKD2 PKD2 SRC SRC PRR5L PRR5L ENSUAMP00000030402 ENSUAMP00000030402 EDN1 EDN1 BRF2 BRF2 ENSUAMP00000030773 ENSUAMP00000030773 ENSUAMP00000030775 ENSUAMP00000030775 ENSUAMP00000031224 ENSUAMP00000031224 ZNF622 ZNF622 RETREG1 RETREG1 MAPK3 MAPK3 CHD6 CHD6 PDK1 PDK1 RIPK3 RIPK3 PPIF PPIF ENSUAMP00000037561 ENSUAMP00000037561 PCGF2 PCGF2 NQO1 NQO1 ENSUAMP00000037129 ENSUAMP00000037129 CHUK CHUK ENSUAMP00000036762 ENSUAMP00000036762 TRPV4 TRPV4 ENSUAMP00000036338 ENSUAMP00000036338 ENSUAMP00000036314 ENSUAMP00000036314 ENSUAMP00000036162 ENSUAMP00000036162 RBM11 RBM11 PDK2 PDK2 ENSUAMP00000035193 ENSUAMP00000035193 ENSUAMP00000035192 ENSUAMP00000035192 NOX1 NOX1 HIF1A HIF1A SRXN1 SRXN1 ADNP2 ADNP2 GSKIP GSKIP ATP13A2 ATP13A2 LONP1 LONP1 TRPM2 TRPM2 SESN2 SESN2 MAPK13 MAPK13 PRKAA1 PRKAA1 ENSUAMP00000032909 ENSUAMP00000032909 PML PML DDIT3 DDIT3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSUAMP00000033749Uncharacterized protein. (344 aa)
TMEM161ATransmembrane protein 161A. (421 aa)
ETV5ETS variant 5. (510 aa)
ENSUAMP00000000893PMSR domain-containing protein. (54 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa)
ENSUAMP00000001033Uncharacterized protein. (106 aa)
ENSUAMP00000001538Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (149 aa)
ENSUAMP00000001779Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (113 aa)
ENSUAMP00000002198Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (143 aa)
ENSUAMP00000002781calpain_III domain-containing protein. (81 aa)
RAD52RAD52 homolog, DNA repair protein. (415 aa)
FOXO1Forkhead box O1. (660 aa)
ZNF277Zinc finger protein 277. (409 aa)
ENSUAMP00000004725G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (253 aa)
ENSUAMP00000004728G_PROTEIN_RECEP_F1_2 domain-containing protein. (155 aa)
ATF4Activating transcription factor 4. (351 aa)
MGAT3Mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase. (545 aa)
ENSUAMP00000004964Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1696 aa)
SETXSenataxin. (2692 aa)
ENSUAMP00000005458Uncharacterized protein. (51 aa)
ANXA1Annexin. (345 aa)
CAPN3Calpain 3; Belongs to the peptidase C2 family. (750 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1212 aa)
MELKNon-specific serine/threonine protein kinase. (642 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (606 aa)
NET1Neuroepithelial cell transforming 1. (542 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
ENSUAMP00000008796KH type-2 domain-containing protein. (92 aa)
ENSUAMP00000008823TAN domain-containing protein. (111 aa)
WNK3WNK lysine deficient protein kinase 3. (1645 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa)
ANKZF1Ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1. (732 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa)
ABL1Tyrosine-protein kinase. (1138 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (848 aa)
ENSUAMP00000010033Uncharacterized protein. (55 aa)
PRDX1Peroxiredoxin 1. (185 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
STK25Serine/threonine kinase 25. (426 aa)
NCF1Neutrophil cytosolic factor 1. (396 aa)
EPAS1Endothelial PAS domain protein 1. (863 aa)
ENSUAMP00000010575Uncharacterized protein. (237 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (153 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit alpha. (315 aa)
ENSUAMP00000011130Uncharacterized protein. (295 aa)
ENSUAMP00000011295VKc domain-containing protein. (163 aa)
ENSUAMP00000011462Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
PRDX3Peroxiredoxin 3. (216 aa)
SELENOSSelenoprotein S. (180 aa)
FOXO3Forkhead box O3. (453 aa)
FOXO3BForkhead box O3B. (244 aa)
ANKRD2Ankyrin repeat domain 2. (335 aa)
ENSUAMP00000012831Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (259 aa)
ARNTAryl hydrocarbon receptor nuclear translocator. (481 aa)
SOD3Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (247 aa)
ROMO1Reactive oxygen species modulator 1. (79 aa)
SLC4A11Solute carrier family 4 member 11. (886 aa)
PJVKPejvakin. (352 aa)
ENSUAMP00000013203DRBM domain-containing protein. (106 aa)
HDAC6Histone deacetylase 6. (1136 aa)
ZFP36L1ZFP36 ring finger protein like 1. (338 aa)
UCP1Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (308 aa)
MAPK1Mitogen-activated protein kinase. (364 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (426 aa)
G6PDGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (572 aa)
RNF112Ring finger protein 112. (630 aa)
PINK1PTEN induced kinase 1. (602 aa)
STOX1Storkhead box 1. (1069 aa)
IMPACTImpact RWD domain protein. (300 aa)
NR4A2Nuclear receptor subfamily 4 group A member 2. (598 aa)
PRKAA2Non-specific serine/threonine protein kinase. (525 aa)
AIF1Allograft inflammatory factor 1. (147 aa)
ERRFI1ERBB receptor feedback inhibitor 1. (410 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
LRRK2Leucine rich repeat kinase 2. (1967 aa)
ENSUAMP00000033750Uncharacterized protein. (66 aa)
ENSUAMP00000016276Uncharacterized protein; Belongs to the DEAD box helicase family. (661 aa)
ENSUAMP00000016418Uncharacterized protein. (553 aa)
DDX3XDEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. (675 aa)
ENSUAMP00000016793BZIP domain-containing protein. (179 aa)
ENSUAMP00000016990Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (169 aa)
STK26Serine/threonine kinase 26. (416 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (598 aa)
ENSUAMP00000018082Uncharacterized protein. (249 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (975 aa)
ENSUAMP00000018315Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (152 aa)
SLC2A4Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
CCSCopper chaperone for superoxide dismutase. (274 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa)
PRDX5Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (219 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (550 aa)
ENSUAMP00000019742Uncharacterized protein. (182 aa)
ARHGEF2Rho/Rac guanine nucleotide exchange factor 2. (1188 aa)
TP53INP1Tumor protein p53 inducible nuclear protein 1. (239 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (658 aa)
TRPA1Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1068 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (266 aa)
ENSUAMP00000020667OSR1_C domain-containing protein. (287 aa)
PTPRKUncharacterized protein. (786 aa)
ENSUAMP00000021280Uncharacterized protein. (128 aa)
YBX3Y-box binding protein 3. (273 aa)
SIRT1Sirtuin 1. (618 aa)
PYCR1Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (320 aa)
ENSUAMP00000021600Uncharacterized protein; Belongs to the metallothionein superfamily. Type 1 family. (203 aa)
OSER1Oxidative stress responsive serine rich 1. (292 aa)
NFE2L1Nuclear factor, erythroid 2 like 1. (798 aa)
PDCD10Programmed cell death 10. (212 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (362 aa)
RCSD1RCSD domain containing 1. (385 aa)
SIGMAR1Sigma non-opioid intracellular receptor 1. (223 aa)
ENSUAMP00000022567Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (161 aa)
PLEKHA1Pleckstrin homology domain containing A1. (374 aa)
PNPT1Polyribonucleotide nucleotidyltransferase 1. (694 aa)
KEAP1Kelch like ECH associated protein 1. (624 aa)
SLC7A11Solute carrier family 7 member 11. (466 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
ENSUAMP00000024788Protein kinase domain-containing protein. (102 aa)
OXR1Oxidation resistance 1. (873 aa)
ENSUAMP00000025110Uncharacterized protein. (88 aa)
ENSUAMP00000025156Thioredoxin domain-containing protein. (198 aa)
BDKRB2Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. (392 aa)
ZNF580Zinc finger protein 580. (199 aa)
ENSUAMP00000026632Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (132 aa)
SLC12A6Solute carrier family 12 member 6. (1090 aa)
RELARELA proto-oncogene, NF-kB subunit. (508 aa)
PPARGC1APPARG coactivator 1 alpha. (761 aa)
TNFAIP3TNF alpha induced protein 3. (790 aa)
GSRGlutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (519 aa)
LRRC8ELeucine rich repeat containing 8 VRAC subunit E. (793 aa)
RPS3Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa)
ENSUAMP00000027993Pannexin_like domain-containing protein. (145 aa)
HTRA2HtrA serine peptidase 2. (458 aa)
MAPK9Mitogen-activated protein kinase. (433 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (746 aa)
PLA2R1Phospholipase A2 receptor 1. (1559 aa)
SPHK1Sphingosine kinase 1. (387 aa)
ENSUAMP00000029334Uncharacterized protein. (124 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (897 aa)
SRCTyrosine-protein kinase. (557 aa)
PRR5LProline rich 5 like. (368 aa)
ENSUAMP00000030402Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (156 aa)
EDN1Endothelin 1. (202 aa)
BRF2BRF2 RNA polymerase III transcription initiation factor subunit. (418 aa)
ENSUAMP00000030773Uncharacterized protein. (87 aa)
ENSUAMP00000030775Uncharacterized protein. (128 aa)
ENSUAMP00000031224Uncharacterized protein. (323 aa)
ZNF622Zinc finger protein 622. (471 aa)
RETREG1Reticulophagy regulator 1. (277 aa)
MAPK3Mitogen-activated protein kinase. (354 aa)
CHD6Chromodomain helicase DNA binding protein 6. (2724 aa)
PDK1Protein-serine/threonine kinase. (438 aa)
RIPK3Receptor interacting serine/threonine kinase 3; Belongs to the protein kinase superfamily. (451 aa)
PPIFPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (210 aa)
ENSUAMP00000037561Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (374 aa)
PCGF2Polycomb group ring finger 2. (344 aa)
NQO1NAD(P)H quinone dehydrogenase 1. (261 aa)
ENSUAMP00000037129Uncharacterized protein. (66 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
ENSUAMP00000036762Thioredoxin domain-containing protein. (152 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (861 aa)
ENSUAMP00000036338Uncharacterized protein. (747 aa)
ENSUAMP00000036314Protein kinase domain-containing protein. (321 aa)
ENSUAMP00000036162Protein kinase domain-containing protein. (462 aa)
RBM11RNA binding motif protein 11. (238 aa)
PDK2Protein-serine/threonine kinase. (249 aa)
ENSUAMP00000035193Uncharacterized protein. (279 aa)
ENSUAMP00000035192Uncharacterized protein. (82 aa)
NOX1NADPH oxidase 1. (594 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (823 aa)
SRXN1Sulfiredoxin. (137 aa)
ADNP2ADNP homeobox 2. (1141 aa)
GSKIPGSK3B interacting protein. (153 aa)
ATP13A2Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (736 aa)
LONP1Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand- specific manner. May regulate mi [...] (961 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1488 aa)
SESN2Sestrin 2. (463 aa)
MAPK13Mitogen-activated protein kinase. (366 aa)
PRKAA1Non-specific serine/threonine protein kinase. (559 aa)
ENSUAMP00000032909Uncharacterized protein. (592 aa)
PMLPromyelocytic leukemia. (877 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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