STRINGSTRING
ENSUAMP00000028083 ENSUAMP00000028083 ENSUAMP00000028028 ENSUAMP00000028028 ENSUAMP00000026961 ENSUAMP00000026961 SART1 SART1 ENSUAMP00000003643 ENSUAMP00000003643 ENSUAMP00000003688 ENSUAMP00000003688 SNU13 SNU13 TXNL4A TXNL4A ZMAT2 ZMAT2 ENSUAMP00000005212 ENSUAMP00000005212 PRPF31 PRPF31 ENSUAMP00000005947 ENSUAMP00000005947 ENSUAMP00000006861 ENSUAMP00000006861 SF3A3 SF3A3 SF3A1 SF3A1 SF3B3 SF3B3 LSM8 LSM8 LSM8-2 LSM8-2 SNRPD2 SNRPD2 ENSUAMP00000010072 ENSUAMP00000010072 ENSUAMP00000010166 ENSUAMP00000010166 ENSUAMP00000010169 ENSUAMP00000010169 ENSUAMP00000011444 ENSUAMP00000011444 PRPF3 PRPF3 SNRPA1 SNRPA1 BUD13 BUD13 SF3B1 SF3B1 PRPF4 PRPF4 ENSUAMP00000033911 ENSUAMP00000033911 DHX16 DHX16 SF3B5 SF3B5 ENSUAMP00000037248 ENSUAMP00000037248 PRPF38A PRPF38A ENSUAMP00000000623 ENSUAMP00000000623 LSM4 LSM4 LSM7 LSM7 RBMX2 RBMX2 ENSUAMP00000000999 ENSUAMP00000000999 ENSUAMP00000001028 ENSUAMP00000001028 EFTUD2 EFTUD2 PRPF6 PRPF6 C19orf54 C19orf54 SNRPB2 SNRPB2 SRRM2 SRRM2 SNRPD2-2 SNRPD2-2 SNRPD2-3 SNRPD2-3 PHF5A PHF5A SMU1 SMU1 ENSUAMP00000033230 ENSUAMP00000033230 MFAP1 MFAP1 PRPF38B PRPF38B WBP4 WBP4 SNRPE SNRPE SNRPD3 SNRPD3 CWC22 CWC22 SNRPD1 SNRPD1 SF3B2 SF3B2 CWC27 CWC27 SNIP1 SNIP1 ENSUAMP00000019788 ENSUAMP00000019788 ENSUAMP00000021056 ENSUAMP00000021056 LSM3 LSM3 ENSUAMP00000026187 ENSUAMP00000026187
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSUAMP00000028083Uncharacterized protein. (88 aa)
ENSUAMP00000028028Sm domain-containing protein. (48 aa)
ENSUAMP00000026961Uncharacterized protein. (113 aa)
SART1Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (765 aa)
ENSUAMP00000003643Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (72 aa)
ENSUAMP00000003688Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (78 aa)
SNU13Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (128 aa)
TXNL4AThioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (188 aa)
ZMAT2Zinc finger matrin-type 2. (192 aa)
ENSUAMP00000005212RED_C domain-containing protein. (188 aa)
PRPF31Pre-mRNA processing factor 31. (499 aa)
ENSUAMP00000005947annotation not available (78 aa)
ENSUAMP00000006861Sm domain-containing protein. (52 aa)
SF3A3Splicing factor 3a subunit 3. (501 aa)
SF3A1Splicing factor 3a subunit 1. (795 aa)
SF3B3Splicing factor 3b subunit 3. (1217 aa)
LSM8U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (92 aa)
LSM8-2U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (96 aa)
SNRPD2Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (53 aa)
ENSUAMP00000010072Sm domain-containing protein. (105 aa)
ENSUAMP00000010166SEC63 domain-containing protein. (329 aa)
ENSUAMP00000010169Uncharacterized protein. (1045 aa)
ENSUAMP00000011444PWI domain-containing protein. (112 aa)
PRPF3Pre-mRNA processing factor 3. (548 aa)
SNRPA1Small nuclear ribonucleoprotein polypeptide A. (257 aa)
BUD13BUD13 homolog. (657 aa)
SF3B1Splicing factor 3b subunit 1. (1122 aa)
PRPF4Pre-mRNA processing factor 4. (369 aa)
ENSUAMP00000033911Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (76 aa)
DHX16DEAH-box helicase 16. (1041 aa)
SF3B5Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa)
ENSUAMP00000037248MPN domain-containing protein. (979 aa)
PRPF38APre-mRNA processing factor 38A. (312 aa)
ENSUAMP00000000623Uncharacterized protein. (86 aa)
LSM4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (139 aa)
LSM7LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. (120 aa)
RBMX2RNA binding motif protein X-linked 2. (311 aa)
ENSUAMP00000000999RRM domain-containing protein. (126 aa)
ENSUAMP00000001028SF3A2 domain-containing protein. (192 aa)
EFTUD2Elongation factor Tu GTP binding domain containing 2. (970 aa)
PRPF6Pre-mRNA processing factor 6. (758 aa)
C19orf54Chromosome 19 open reading frame 54. (346 aa)
SNRPB2Small nuclear ribonucleoprotein polypeptide B2. (224 aa)
SRRM2Serine/arginine repetitive matrix 2. (2862 aa)
SNRPD2-2Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (123 aa)
SNRPD2-3Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (118 aa)
PHF5APHD finger protein 5A. (85 aa)
SMU1SMU1 DNA replication regulator and spliceosomal factor. (513 aa)
ENSUAMP00000033230RRM domain-containing protein. (125 aa)
MFAP1Microfibril associated protein 1. (439 aa)
PRPF38BPre-mRNA processing factor 38B. (549 aa)
WBP4WW domain binding protein 4. (373 aa)
SNRPESmall nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (88 aa)
SNRPD3Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (126 aa)
CWC22CWC22 spliceosome associated protein homolog. (910 aa)
SNRPD1Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (117 aa)
SF3B2Splicing factor 3b subunit 2. (910 aa)
CWC27CWC27 spliceosome associated cyclophilin. (340 aa)
SNIP1Smad nuclear interacting protein 1. (392 aa)
ENSUAMP00000019788Uncharacterized protein. (1338 aa)
ENSUAMP00000021056Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (153 aa)
LSM3U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (114 aa)
ENSUAMP00000026187Sm domain-containing protein. (72 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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