(20 nodes) Ceramide binding network (Ursus americanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CPTP	Ceramide-1-phosphate transfer protein. (214 aa)
	EPDR1	Ependymin related 1. (122 aa)
	ENSUAMP00000010224	PH domain-containing protein. (66 aa)
	LAPTM4A	Lysosomal protein transmembrane 4 alpha. (233 aa)
	GLTPD2	Glycolipid transfer protein domain containing 2. (307 aa)
	PSAP	Prosaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling. (524 aa)
	PLEKHA8	Pleckstrin homology domain containing A8. (519 aa)
	ENSUAMP00000026830	Uncharacterized protein. (454 aa)
	CLIP3	CAP-Gly domain containing linker protein 3. (546 aa)
	GLTP	Glycolipid transfer protein. (209 aa)
	ENSUAMP00000034850	Uncharacterized protein. (294 aa)
	ENSUAMP00000034023	Uncharacterized protein. (155 aa)
	ENSUAMP00000023390	Uncharacterized protein. (286 aa)
	CLN8	CLN8 transmembrane ER and ERGIC protein. (288 aa)
	ENSUAMP00000019477	Uncharacterized protein. (393 aa)
	PLA2G4A	Phospholipase A2. (756 aa)
	RTN4R	Reticulon 4 receptor. (472 aa)
	PLEKHA3	Pleckstrin homology domain containing A3. (300 aa)
	PLTP	Phospholipid transfer protein. (496 aa)
	ENSUAMP00000012758	START domain-containing protein. (327 aa)

Your Current Organism:

Ursus americanus

NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CPTP	GLTP	ENSUAMP00000016039	ENSUAMP00000036723	Ceramide-1-phosphate transfer protein.	Glycolipid transfer protein.	0.530
ENSUAMP00000010224	ENSUAMP00000012758	ENSUAMP00000010224	ENSUAMP00000012758	PH domain-containing protein.	START domain-containing protein.	0.900
ENSUAMP00000010224	GLTP	ENSUAMP00000010224	ENSUAMP00000036723	PH domain-containing protein.	Glycolipid transfer protein.	0.429
ENSUAMP00000012758	ENSUAMP00000010224	ENSUAMP00000012758	ENSUAMP00000010224	START domain-containing protein.	PH domain-containing protein.	0.900
ENSUAMP00000012758	GLTP	ENSUAMP00000012758	ENSUAMP00000036723	START domain-containing protein.	Glycolipid transfer protein.	0.429
ENSUAMP00000019477	RTN4R	ENSUAMP00000019477	ENSUAMP00000013412	Uncharacterized protein.	Reticulon 4 receptor.	0.459
ENSUAMP00000023390	ENSUAMP00000034850	ENSUAMP00000023390	ENSUAMP00000034850	Uncharacterized protein.	Uncharacterized protein.	0.543
ENSUAMP00000026830	RTN4R	ENSUAMP00000026830	ENSUAMP00000013412	Uncharacterized protein.	Reticulon 4 receptor.	0.459
ENSUAMP00000034023	LAPTM4A	ENSUAMP00000034023	ENSUAMP00000009767	Uncharacterized protein.	Lysosomal protein transmembrane 4 alpha.	0.950
ENSUAMP00000034850	ENSUAMP00000023390	ENSUAMP00000034850	ENSUAMP00000023390	Uncharacterized protein.	Uncharacterized protein.	0.543
GLTP	CPTP	ENSUAMP00000036723	ENSUAMP00000016039	Glycolipid transfer protein.	Ceramide-1-phosphate transfer protein.	0.530
GLTP	ENSUAMP00000010224	ENSUAMP00000036723	ENSUAMP00000010224	Glycolipid transfer protein.	PH domain-containing protein.	0.429
GLTP	ENSUAMP00000012758	ENSUAMP00000036723	ENSUAMP00000012758	Glycolipid transfer protein.	START domain-containing protein.	0.429
GLTP	GLTPD2	ENSUAMP00000036723	ENSUAMP00000006182	Glycolipid transfer protein.	Glycolipid transfer protein domain containing 2.	0.521
GLTPD2	GLTP	ENSUAMP00000006182	ENSUAMP00000036723	Glycolipid transfer protein domain containing 2.	Glycolipid transfer protein.	0.521
LAPTM4A	ENSUAMP00000034023	ENSUAMP00000009767	ENSUAMP00000034023	Lysosomal protein transmembrane 4 alpha.	Uncharacterized protein.	0.950
RTN4R	ENSUAMP00000019477	ENSUAMP00000013412	ENSUAMP00000019477	Reticulon 4 receptor.	Uncharacterized protein.	0.459
RTN4R	ENSUAMP00000026830	ENSUAMP00000013412	ENSUAMP00000026830	Reticulon 4 receptor.	Uncharacterized protein.	0.459