(34 nodes) Sperm midpiece network (Ursus americanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FAM71D	Family with sequence similarity 71 member D. (393 aa)
	LYZL6	Lysozyme like 6; Belongs to the glycosyl hydrolase 22 family. (148 aa)
	SQSTM1	Sequestosome 1. (491 aa)
	ENSUAMP00000034850	Uncharacterized protein. (294 aa)
	SLC26A3	Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (691 aa)
	TBC1D21	TBC1 domain family member 21. (336 aa)
	TACR1	Tachykinin receptor 1; Belongs to the G-protein coupled receptor 1 family. (407 aa)
	SLC9A3R1	Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (366 aa)
	AKAP4	A-kinase anchoring protein 4. (856 aa)
	CCR6	C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (381 aa)
	CFAP65	Cilia and flagella associated protein 65. (1850 aa)
	ENSUAMP00000025814	Uncharacterized protein. (1846 aa)
	SLC26A6	Solute carrier family 26 member 6. (758 aa)
	MROH2B	Maestro heat like repeat family member 2B. (1575 aa)
	ENSUAMP00000023390	Uncharacterized protein. (286 aa)
	TACR2	Tachykinin receptor 2; Belongs to the G-protein coupled receptor 1 family. (383 aa)
	TACR3	Tachykinin receptor 3; Belongs to the G-protein coupled receptor 1 family. (460 aa)
	RAP1A	RAP1A, member of RAS oncogene family. (184 aa)
	ENSUAMP00000016191	Uncharacterized protein. (112 aa)
	ENSUAMP00000016003	Uncharacterized protein. (447 aa)
	CCDC172	Coiled-coil domain containing 172. (245 aa)
	ENSUAMP00000013294	Uncharacterized protein. (724 aa)
	SPATA19	Spermatogenesis associated 19. (190 aa)
	CD52	CD52 molecule. (66 aa)
	ENSUAMP00000006890	IFT81_CH domain-containing protein. (235 aa)
	CFAP69	Cilia and flagella associated protein 69. (629 aa)
	IL4I1	Interleukin 4 induced 1. (572 aa)
	RHO	Rhodopsin. (348 aa)
	ATG16L1	Autophagy related 16 like 1. (602 aa)
	CFAP58	Cilia and flagella associated protein 58. (831 aa)
	AKAP3	A-kinase anchoring protein 3. (510 aa)
	FSIP2	Fibrous sheath interacting protein 2. (6461 aa)
	ENSUAMP00000001008	Uncharacterized protein. (6384 aa)
	HYAL3	Hyaluronidase. (417 aa)

Your Current Organism:

Ursus americanus

NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKAP3	ENSUAMP00000001008	ENSUAMP00000002816	ENSUAMP00000001008	A-kinase anchoring protein 3.	Uncharacterized protein.	0.443
AKAP3	FSIP2	ENSUAMP00000002816	ENSUAMP00000001512	A-kinase anchoring protein 3.	Fibrous sheath interacting protein 2.	0.443
AKAP3	SPATA19	ENSUAMP00000002816	ENSUAMP00000012809	A-kinase anchoring protein 3.	Spermatogenesis associated 19.	0.553
AKAP4	ENSUAMP00000001008	ENSUAMP00000029742	ENSUAMP00000001008	A-kinase anchoring protein 4.	Uncharacterized protein.	0.582
AKAP4	ENSUAMP00000016003	ENSUAMP00000029742	ENSUAMP00000016003	A-kinase anchoring protein 4.	Uncharacterized protein.	0.463
AKAP4	FSIP2	ENSUAMP00000029742	ENSUAMP00000001512	A-kinase anchoring protein 4.	Fibrous sheath interacting protein 2.	0.582
ATG16L1	SQSTM1	ENSUAMP00000036519	ENSUAMP00000035933	Autophagy related 16 like 1.	Sequestosome 1.	0.602
ENSUAMP00000001008	AKAP3	ENSUAMP00000001008	ENSUAMP00000002816	Uncharacterized protein.	A-kinase anchoring protein 3.	0.443
ENSUAMP00000001008	AKAP4	ENSUAMP00000001008	ENSUAMP00000029742	Uncharacterized protein.	A-kinase anchoring protein 4.	0.582
ENSUAMP00000006890	SLC9A3R1	ENSUAMP00000006890	ENSUAMP00000030868	IFT81_CH domain-containing protein.	Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.	0.461
ENSUAMP00000013294	ENSUAMP00000025814	ENSUAMP00000013294	ENSUAMP00000025814	Uncharacterized protein.	Uncharacterized protein.	0.922
ENSUAMP00000016003	AKAP4	ENSUAMP00000016003	ENSUAMP00000029742	Uncharacterized protein.	A-kinase anchoring protein 4.	0.463
ENSUAMP00000016003	ENSUAMP00000016191	ENSUAMP00000016003	ENSUAMP00000016191	Uncharacterized protein.	Uncharacterized protein.	0.898
ENSUAMP00000016191	ENSUAMP00000016003	ENSUAMP00000016191	ENSUAMP00000016003	Uncharacterized protein.	Uncharacterized protein.	0.898
ENSUAMP00000023390	ENSUAMP00000034850	ENSUAMP00000023390	ENSUAMP00000034850	Uncharacterized protein.	Uncharacterized protein.	0.543
ENSUAMP00000023390	SQSTM1	ENSUAMP00000023390	ENSUAMP00000035933	Uncharacterized protein.	Sequestosome 1.	0.588
ENSUAMP00000025814	ENSUAMP00000013294	ENSUAMP00000025814	ENSUAMP00000013294	Uncharacterized protein.	Uncharacterized protein.	0.922
ENSUAMP00000034850	ENSUAMP00000023390	ENSUAMP00000034850	ENSUAMP00000023390	Uncharacterized protein.	Uncharacterized protein.	0.543
ENSUAMP00000034850	SQSTM1	ENSUAMP00000034850	ENSUAMP00000035933	Uncharacterized protein.	Sequestosome 1.	0.588
FSIP2	AKAP3	ENSUAMP00000001512	ENSUAMP00000002816	Fibrous sheath interacting protein 2.	A-kinase anchoring protein 3.	0.443