STRINGSTRING
ENSUAMP00000006452 ENSUAMP00000006452 ZBTB10 ZBTB10 PPP1R10 PPP1R10 NUP160 NUP160 ENSUAMP00000032974 ENSUAMP00000032974 SEC13 SEC13 DYNLT3 DYNLT3 FBXW11 FBXW11 SYCP3 SYCP3 ENSUAMP00000032054 ENSUAMP00000032054 SUN2 SUN2 RANGAP1 RANGAP1 TINF2 TINF2 MDP1 MDP1 CHMP4A CHMP4A FBXO28 FBXO28 NCAPD3 NCAPD3 REC8 REC8 ENSUAMP00000031131 ENSUAMP00000031131 SMC1A SMC1A CHMP7 CHMP7 SMARCA5 SMARCA5 ZWILCH ZWILCH CENPW CENPW MIS18BP1 MIS18BP1 NDEL1 NDEL1 ENSUAMP00000029725 ENSUAMP00000029725 SIN3A SIN3A ENSUAMP00000029249 ENSUAMP00000029249 ENSUAMP00000029109 ENSUAMP00000029109 HNRNPU HNRNPU EZH2 EZH2 CBX5 CBX5 OIP5 OIP5 ENSUAMP00000028112 ENSUAMP00000028112 ENSUAMP00000028111 ENSUAMP00000028111 ENSUAMP00000027974 ENSUAMP00000027974 TP53BP1 TP53BP1 SKA1 SKA1 PPP2CB PPP2CB WRN WRN ENSUAMP00000027388 ENSUAMP00000027388 AFMID AFMID BIRC5 BIRC5 SMCHD1 SMCHD1 CEBPB CEBPB CENPT CENPT KAT5 KAT5 CENPQ CENPQ ENSUAMP00000026733 ENSUAMP00000026733 CHMP1A CHMP1A ENSUAMP00000026245 ENSUAMP00000026245 ZNF330 ZNF330 ERCC1 ERCC1 ENSUAMP00000025844 ENSUAMP00000025844 SPO11 SPO11 NSMCE1 NSMCE1 CENPL CENPL KMT5B KMT5B ENSUAMP00000024868 ENSUAMP00000024868 CHMP6 CHMP6 ENSUAMP00000024860 ENSUAMP00000024860 KIF2C KIF2C ENSUAMP00000024673 ENSUAMP00000024673 SIRT6 SIRT6 ZNF827 ZNF827 FAM193A FAM193A ENSUAMP00000007405 ENSUAMP00000007405 CENPM CENPM ENSUAMP00000007487 ENSUAMP00000007487 GATAD2B GATAD2B IKZF1 IKZF1 CENPF CENPF UPF1 UPF1 DNMT1 DNMT1 DMC1 DMC1 CENPO CENPO ENSUAMP00000008823 ENSUAMP00000008823 APC APC CHMP2B CHMP2B DYNC1I1 DYNC1I1 ENSUAMP00000000068 ENSUAMP00000000068 ENSUAMP00000000198 ENSUAMP00000000198 ENSUAMP00000000300 ENSUAMP00000000300 ORC1 ORC1 WRNIP1 WRNIP1 ENSUAMP00000000618 ENSUAMP00000000618 TOP2A TOP2A NABP1 NABP1 SKA3 SKA3 ENSUAMP00000001565 ENSUAMP00000001565 ENSUAMP00000001591 ENSUAMP00000001591 KNSTRN KNSTRN ENSUAMP00000001644 ENSUAMP00000001644 ENSUAMP00000001691 ENSUAMP00000001691 CHMP1B CHMP1B ENSUAMP00000001840 ENSUAMP00000001840 ENSUAMP00000002092 ENSUAMP00000002092 ENSUAMP00000002099 ENSUAMP00000002099 INCENP INCENP TERF2 TERF2 ZNF207 ZNF207 ENSUAMP00000002444 ENSUAMP00000002444 ENSUAMP00000002466 ENSUAMP00000002466 ENSUAMP00000002604 ENSUAMP00000002604 RSKR RSKR ENSUAMP00000003044 ENSUAMP00000003044 SUV39H2 SUV39H2 ENSUAMP00000003100 ENSUAMP00000003100 SMC1B SMC1B TERB1 TERB1 ENSUAMP00000003355 ENSUAMP00000003355 ENSUAMP00000003358 ENSUAMP00000003358 NSL1 NSL1 SPC25 SPC25 ENSUAMP00000003566 ENSUAMP00000003566 ENSUAMP00000003585 ENSUAMP00000003585 ENSUAMP00000003633 ENSUAMP00000003633 GALK1 GALK1 CHMP2A CHMP2A ENSUAMP00000003972 ENSUAMP00000003972 HELLS HELLS SEPTIN7 SEPTIN7 KIF2B KIF2B ENSUAMP00000004397 ENSUAMP00000004397 ENSUAMP00000004502 ENSUAMP00000004502 XRCC5 XRCC5 ENSUAMP00000004606 ENSUAMP00000004606 ENSUAMP00000004684 ENSUAMP00000004684 ENSUAMP00000004964 ENSUAMP00000004964 ENSUAMP00000005048 ENSUAMP00000005048 KAT2B KAT2B THOC1 THOC1 TEX14 TEX14 CTC1 CTC1 AURKB AURKB SEPTIN6 SEPTIN6 TOX4 TOX4 DSCC1 DSCC1 ATRX ATRX PSEN2 PSEN2 DYNC1LI1 DYNC1LI1 ENSUAMP00000036811 ENSUAMP00000036811 ENSUAMP00000036809 ENSUAMP00000036809 ENSUAMP00000036686 ENSUAMP00000036686 ENSUAMP00000036676 ENSUAMP00000036676 HSF1 HSF1 CENPU CENPU NUP107 NUP107 DCLRE1B DCLRE1B FMR1 FMR1 FEN1 FEN1 NSMCE2 NSMCE2 ENSUAMP00000023307 ENSUAMP00000023307 TRAPPC12 TRAPPC12 NBN NBN PPP2CA PPP2CA ZW10 ZW10 NCAPG NCAPG SEPTIN2 SEPTIN2 SEH1L SEH1L KMT5C KMT5C DCTN3 DCTN3 TERF2IP TERF2IP ENSUAMP00000022173 ENSUAMP00000022173 CBX1 CBX1 MRE11 MRE11 CHMP4C CHMP4C DHX36 DHX36 ENSUAMP00000021647 ENSUAMP00000021647 ENSUAMP00000021642 ENSUAMP00000021642 PIF1 PIF1 BAZ1B BAZ1B SPOUT1 SPOUT1 TFIP11 TFIP11 ENSUAMP00000020419 ENSUAMP00000020419 ACD ACD ERCC6L ERCC6L RCC2 RCC2 ENSUAMP00000019602 ENSUAMP00000019602 PINX1 PINX1 MAD2L1 MAD2L1 KDM4B KDM4B CHAMP1 CHAMP1 NDE1 NDE1 POLD1 POLD1 ENSUAMP00000018470 ENSUAMP00000018470 SPAG5 SPAG5 ENSUAMP00000018174 ENSUAMP00000018174 ENSUAMP00000018101 ENSUAMP00000018101 KIF18A KIF18A SGO2 SGO2 BRCA2 BRCA2 CDCA8 CDCA8 MEAF6 MEAF6 SMC4 SMC4 STN1 STN1 NUP98 NUP98 MTA2 MTA2 NABP2 NABP2 ENSUAMP00000035738 ENSUAMP00000035738 SMC3 SMC3 DAXX DAXX CENPB CENPB RASSF4 RASSF4 ENSUAMP00000035191 ENSUAMP00000035191 DOT1L DOT1L CENPI CENPI SNAI1 SNAI1 HMBOX1 HMBOX1 XPO1 XPO1 RIF1 RIF1 NSMCE4A NSMCE4A ENSUAMP00000034422 ENSUAMP00000034422 CKAP5 CKAP5 PHF6 PHF6 ENSUAMP00000033824 ENSUAMP00000033824 NUP43 NUP43 PHF2 PHF2 BOD1L1 BOD1L1 RASSF2 RASSF2 CHEK1 CHEK1 BAZ1A BAZ1A TTK TTK NEK2 NEK2 ENSUAMP00000009187 ENSUAMP00000009187 BUB3 BUB3 HAT1 HAT1 DSN1 DSN1 NUP37 NUP37 THOC6 THOC6 RBBP7 RBBP7 ZBTB48 ZBTB48 ENSUAMP00000009862 ENSUAMP00000009862 ENSUAMP00000009972 ENSUAMP00000009972 KAT8 KAT8 ANAPC16 ANAPC16 LRIF1 LRIF1 AHCTF1 AHCTF1 ENSUAMP00000011819 ENSUAMP00000011819 ENSUAMP00000011824 ENSUAMP00000011824 NDC80 NDC80 ENSUAMP00000011876 ENSUAMP00000011876 ENSUAMP00000012508 ENSUAMP00000012508 BUB1 BUB1 NUP85 NUP85 XRCC1 XRCC1 DNMT3A DNMT3A THOC3 THOC3 PPP1CC PPP1CC CENPC CENPC ORC2 ORC2 CHEK2 CHEK2 LRWD1 LRWD1 TEP1 TEP1 ENSUAMP00000014202 ENSUAMP00000014202 ENSUAMP00000014243 ENSUAMP00000014243 SPC24 SPC24 ORC4 ORC4 ZNF618 ZNF618 MIS12 MIS12 ENSUAMP00000015206 ENSUAMP00000015206 CHMP5 CHMP5 PML PML CBX3 CBX3 DCTN2 DCTN2 NGDN NGDN CDCA5 CDCA5 MIS18A MIS18A ENSUAMP00000015392 ENSUAMP00000015392 WDR82 WDR82 ENSUAMP00000016108 ENSUAMP00000016108 PAFAH1B1 PAFAH1B1 TNKS TNKS MACROH2A1 MACROH2A1 ENSUAMP00000017193 ENSUAMP00000017193 THOC5 THOC5 ENSUAMP00000017329 ENSUAMP00000017329 ZWINT ZWINT SKA2 SKA2 CENPP CENPP TERT TERT ENSUAMP00000017773 ENSUAMP00000017773 GAR1 GAR1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSUAMP00000006452Zinc-hook domain-containing protein. (855 aa)
ZBTB10Zinc finger and BTB domain containing 10. (873 aa)
PPP1R10Protein phosphatase 1 regulatory subunit 10. (941 aa)
NUP160Nucleoporin 160. (1435 aa)
ENSUAMP00000032974Uncharacterized protein. (190 aa)
SEC13SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (311 aa)
DYNLT3Dynein light chain Tctex-type 3. (112 aa)
FBXW11F-box and WD repeat domain containing 11. (543 aa)
SYCP3Synaptonemal complex protein 3. (217 aa)
ENSUAMP00000032054Uncharacterized protein. (105 aa)
SUN2Sad1 and UNC84 domain containing 2. (725 aa)
RANGAP1Ran GTPase activating protein 1. (589 aa)
TINF2TERF1 interacting nuclear factor 2. (452 aa)
MDP1Uncharacterized protein. (210 aa)
CHMP4ACharged multivesicular body protein 4A. (235 aa)
FBXO28F-box protein 28. (368 aa)
NCAPD3Condensin-2 complex subunit D3; Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. (1491 aa)
REC8REC8 meiotic recombination protein. (482 aa)
ENSUAMP00000031131Protein kinase domain-containing protein. (264 aa)
SMC1AStructural maintenance of chromosomes protein. (1239 aa)
CHMP7Charged multivesicular body protein 7. (482 aa)
SMARCA5SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5. (1047 aa)
ZWILCHZwilch kinetochore protein. (584 aa)
CENPWCentromere protein W. (88 aa)
MIS18BP1MIS18 binding protein 1. (1108 aa)
NDEL1NudE neurodevelopment protein 1 like 1. (345 aa)
ENSUAMP00000029725Uncharacterized protein. (1947 aa)
SIN3ASIN3 transcription regulator family member A. (1275 aa)
ENSUAMP00000029249Uncharacterized protein. (112 aa)
ENSUAMP00000029109RECA_2 domain-containing protein. (300 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U. (825 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (746 aa)
CBX5Chromobox 5. (191 aa)
OIP5Opa interacting protein 5. (229 aa)
ENSUAMP00000028112CBFD_NFYB_HMF domain-containing protein. (55 aa)
ENSUAMP00000028111CAP-Gly domain-containing protein. (1261 aa)
ENSUAMP00000027974Uncharacterized protein. (70 aa)
TP53BP1Tumor protein p53 binding protein 1. (1542 aa)
SKA1Spindle and kinetochore associated complex subunit 1. (255 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
WRNWRN RecQ like helicase. (1363 aa)
ENSUAMP00000027388Uncharacterized protein. (60 aa)
AFMIDKynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. (285 aa)
BIRC5Baculoviral IAP repeat containing 5. (142 aa)
SMCHD1Structural maintenance of chromosomes flexible hinge domain containing 1. (1174 aa)
CEBPBCCAAT/enhancer-binding protein. (346 aa)
CENPTCentromere protein T. (490 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa)
CENPQCentromere protein Q. (268 aa)
ENSUAMP00000026733ANK_REP_REGION domain-containing protein. (314 aa)
CHMP1ACharged multivesicular body protein 1A. (196 aa)
ENSUAMP00000026245ZAD domain-containing protein. (305 aa)
ZNF330Zinc finger protein 330. (320 aa)
ERCC1ERCC excision repair 1, endonuclease non-catalytic subunit. (294 aa)
ENSUAMP00000025844Uncharacterized protein. (269 aa)
SPO11SPO11 initiator of meiotic double stranded breaks. (396 aa)
NSMCE1NSE1 homolog, SMC5-SMC6 complex component. (283 aa)
CENPLCentromere protein L. (346 aa)
KMT5BLysine methyltransferase 5B. (853 aa)
ENSUAMP00000024868Uncharacterized protein. (79 aa)
CHMP6Charged multivesicular body protein 6. (193 aa)
ENSUAMP00000024860Uncharacterized protein. (221 aa)
KIF2CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (725 aa)
ENSUAMP00000024673Uncharacterized protein. (102 aa)
SIRT6Sirtuin 6. (338 aa)
ZNF827Zinc finger protein 827. (1003 aa)
FAM193AFamily with sequence similarity 193 member A. (1110 aa)
ENSUAMP00000007405Uncharacterized protein. (485 aa)
CENPMCentromere protein M. (146 aa)
ENSUAMP00000007487Chromo domain-containing protein. (72 aa)
GATAD2BGATA zinc finger domain containing 2B. (593 aa)
IKZF1IKAROS family zinc finger 1. (347 aa)
CENPFCentromere protein F. (3110 aa)
UPF1UPF1 RNA helicase and ATPase. (1119 aa)
DNMT1DNA methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (981 aa)
DMC1Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (328 aa)
CENPOCentromere protein O. (285 aa)
ENSUAMP00000008823TAN domain-containing protein. (111 aa)
APCAPC regulator of WNT signaling pathway. (2832 aa)
CHMP2BCharged multivesicular body protein 2B. (213 aa)
DYNC1I1Dynein cytoplasmic 1 intermediate chain 1. (590 aa)
ENSUAMP00000000068FHA domain-containing protein. (85 aa)
ENSUAMP00000000198Uncharacterized protein. (238 aa)
ENSUAMP00000000300Bromo domain-containing protein. (84 aa)
ORC1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (858 aa)
WRNIP1WRN helicase interacting protein 1. (663 aa)
ENSUAMP00000000618GFA domain-containing protein. (285 aa)
TOP2ADNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1505 aa)
NABP1Nucleic acid binding protein 1. (199 aa)
SKA3Spindle and kinetochore associated complex subunit 3. (413 aa)
ENSUAMP00000001565Uncharacterized protein. (305 aa)
ENSUAMP00000001591Uncharacterized protein. (65 aa)
KNSTRNKinetochore localized astrin (SPAG5) binding protein. (238 aa)
ENSUAMP00000001644GFA domain-containing protein. (213 aa)
ENSUAMP00000001691Uncharacterized protein. (297 aa)
CHMP1BCharged multivesicular body protein 1B. (199 aa)
ENSUAMP00000001840Uncharacterized protein. (586 aa)
ENSUAMP00000002092Uncharacterized protein. (63 aa)
ENSUAMP00000002099AAA_23 domain-containing protein. (1035 aa)
INCENPInner centromere protein. (879 aa)
TERF2Telomeric repeat binding factor 2. (521 aa)
ZNF207Zinc finger protein 207. (448 aa)
ENSUAMP00000002444SCAN box domain-containing protein. (418 aa)
ENSUAMP00000002466Uncharacterized protein. (487 aa)
ENSUAMP00000002604CAF1C_H4-bd domain-containing protein. (133 aa)
RSKRRibosomal protein S6 kinase related. (387 aa)
ENSUAMP00000003044Uncharacterized protein. (204 aa)
SUV39H2Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (483 aa)
ENSUAMP00000003100Uncharacterized protein. (106 aa)
SMC1BStructural maintenance of chromosomes protein. (1194 aa)
TERB1Telomere repeat binding bouquet formation protein 1. (726 aa)
ENSUAMP00000003355Uncharacterized protein. (76 aa)
ENSUAMP00000003358SER_THR_PHOSPHATASE domain-containing protein. (106 aa)
NSL1NSL1 component of MIS12 kinetochore complex. (178 aa)
SPC25SPC25 component of NDC80 kinetochore complex. (226 aa)
ENSUAMP00000003566Uncharacterized protein; Belongs to the RNA polymerase beta chain family. (942 aa)
ENSUAMP00000003585Uncharacterized protein. (112 aa)
ENSUAMP00000003633Uncharacterized protein. (444 aa)
GALK1Galactokinase 1. (392 aa)
CHMP2ACharged multivesicular body protein 2A. (222 aa)
ENSUAMP00000003972Rod_C domain-containing protein. (136 aa)
HELLSHelicase, lymphoid specific. (827 aa)
SEPTIN7Septin 7; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (436 aa)
KIF2BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (683 aa)
ENSUAMP00000004397Uncharacterized protein. (297 aa)
ENSUAMP00000004502annotation not available (297 aa)
XRCC5X-ray repair cross complementing 5. (501 aa)
ENSUAMP00000004606Uncharacterized protein. (1041 aa)
ENSUAMP00000004684Uncharacterized protein. (191 aa)
ENSUAMP00000004964Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1696 aa)
ENSUAMP00000005048Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (241 aa)
KAT2BLysine acetyltransferase 2B. (629 aa)
THOC1THO complex 1. (792 aa)
TEX14Testis expressed 14, intercellular bridge forming factor. (1425 aa)
CTC1CST telomere replication complex component 1. (1227 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (344 aa)
SEPTIN6Septin 6; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (431 aa)
TOX4TOX high mobility group box family member 4. (611 aa)
DSCC1DNA replication and sister chromatid cohesion 1. (392 aa)
ATRXATRX chromatin remodeler. (2087 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (479 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (524 aa)
ENSUAMP00000036811Uncharacterized protein. (669 aa)
ENSUAMP00000036809Uncharacterized protein. (68 aa)
ENSUAMP00000036686TRF domain-containing protein. (247 aa)
ENSUAMP00000036676JmjN domain-containing protein. (161 aa)
HSF1Heat shock transcription factor 1. (554 aa)
CENPUCentromere protein U. (384 aa)
NUP107Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (641 aa)
DCLRE1BDNA cross-link repair 1B. (454 aa)
FMR1Fragile X mental retardation 1. (621 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa)
NSMCE2NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. (157 aa)
ENSUAMP00000023307Uncharacterized protein. (243 aa)
TRAPPC12Trafficking protein particle complex 12. (786 aa)
NBNNibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (753 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
ZW10Zw10 kinetochore protein. (739 aa)
NCAPGNon-SMC condensin I complex subunit G. (1015 aa)
SEPTIN2Septin 2; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (362 aa)
SEH1LSEH1 like nucleoporin; Belongs to the WD repeat SEC13 family. (357 aa)
KMT5CLysine methyltransferase 5C. (467 aa)
DCTN3Dynactin subunit 3. (186 aa)
TERF2IPTERF2 interacting protein. (401 aa)
ENSUAMP00000022173Uncharacterized protein. (86 aa)
CBX1Chromobox 1. (185 aa)
MRE11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (708 aa)
CHMP4CCharged multivesicular body protein 4C. (237 aa)
DHX36DEAH-box helicase 36. (964 aa)
ENSUAMP00000021647Rad21_Rec8_N domain-containing protein. (566 aa)
ENSUAMP00000021642Rad21_Rec8 domain-containing protein. (69 aa)
PIF1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] (646 aa)
BAZ1BBromodomain adjacent to zinc finger domain 1B. (1482 aa)
SPOUT1SPOUT domain containing methyltransferase 1. (376 aa)
TFIP11Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...] (777 aa)
ENSUAMP00000020419Uncharacterized protein. (490 aa)
ACDACD shelterin complex subunit and telomerase recruitment factor. (452 aa)
ERCC6LERCC excision repair 6 like, spindle assembly checkpoint helicase. (1117 aa)
RCC2Regulator of chromosome condensation 2. (508 aa)
ENSUAMP00000019602AAA_23 domain-containing protein. (520 aa)
PINX1PIN2 (TERF1) interacting telomerase inhibitor 1. (318 aa)
MAD2L1Mitotic arrest deficient 2 like 1. (205 aa)
KDM4BLysine demethylase 4B. (797 aa)
CHAMP1Chromosome alignment maintaining phosphoprotein 1. (674 aa)
NDE1NudE neurodevelopment protein 1. (346 aa)
POLD1DNA polymerase. (1109 aa)
ENSUAMP00000018470Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (298 aa)
SPAG5Sperm associated antigen 5. (720 aa)
ENSUAMP00000018174Uncharacterized protein. (156 aa)
ENSUAMP00000018101Uncharacterized protein. (269 aa)
KIF18AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (890 aa)
SGO2Shugoshin 2. (1094 aa)
BRCA2BRCA2 DNA repair associated. (3458 aa)
CDCA8Cell division cycle associated 8. (281 aa)
MEAF6MYST/Esa1 associated factor 6. (202 aa)
SMC4Structural maintenance of chromosomes protein. (1333 aa)
STN1STN1 subunit of CST complex. (285 aa)
NUP98Nucleoporin 98. (1157 aa)
MTA2Metastasis associated 1 family member 2. (668 aa)
NABP2Nucleic acid binding protein 2. (211 aa)
ENSUAMP00000035738Uncharacterized protein. (1448 aa)
SMC3Structural maintenance of chromosomes protein. (1215 aa)
DAXXDeath domain associated protein. (756 aa)
CENPBCentromere protein B. (608 aa)
RASSF4Ras association domain family member 4. (321 aa)
ENSUAMP00000035191SKA2 domain-containing protein. (57 aa)
DOT1LHistone-lysine N-methyltransferase, H3 lysine-79 specific. (1520 aa)
CENPICentromere protein I. (725 aa)
SNAI1Snail family transcriptional repressor 1. (259 aa)
HMBOX1Homeobox containing 1. (408 aa)
XPO1Exportin 1. (1071 aa)
RIF1Replication timing regulatory factor 1. (2251 aa)
NSMCE4ANon-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (350 aa)
ENSUAMP00000034422Uncharacterized protein. (251 aa)
CKAP5Cytoskeleton associated protein 5. (1740 aa)
PHF6PHD finger protein 6. (365 aa)
ENSUAMP00000033824CDT1 domain-containing protein. (780 aa)
NUP43Nucleoporin 43. (380 aa)
PHF2PHD finger protein 2. (1088 aa)
BOD1L1Biorientation of chromosomes in cell division 1 like 1. (2862 aa)
RASSF2Ras association domain family member 2. (361 aa)
CHEK1Checkpoint kinase 1; Belongs to the protein kinase superfamily. (476 aa)
BAZ1ABromodomain adjacent to zinc finger domain 1A. (1557 aa)
TTKTTK protein kinase. (853 aa)
NEK2NIMA related kinase 2. (444 aa)
ENSUAMP00000009187Uncharacterized protein. (1046 aa)
BUB3BUB3 mitotic checkpoint protein. (326 aa)
HAT1Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. (378 aa)
DSN1DSN1 component of MIS12 kinetochore complex. (356 aa)
NUP37Nucleoporin 37. (276 aa)
THOC6THO complex 6. (341 aa)
RBBP7RB binding protein 7, chromatin remodeling factor. (427 aa)
ZBTB48Zinc finger and BTB domain containing 48. (688 aa)
ENSUAMP00000009862Uncharacterized protein. (1645 aa)
ENSUAMP00000009972Uncharacterized protein. (80 aa)
KAT8Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (458 aa)
ANAPC16Anaphase promoting complex subunit 16. (125 aa)
LRIF1Ligand dependent nuclear receptor interacting factor 1. (762 aa)
AHCTF1AT-hook containing transcription factor 1. (2138 aa)
ENSUAMP00000011819GFA domain-containing protein. (267 aa)
ENSUAMP00000011824GFA domain-containing protein. (264 aa)
NDC80NDC80 kinetochore complex component. (642 aa)
ENSUAMP00000011876ERCC4 domain-containing protein. (277 aa)
ENSUAMP00000012508SMC_N domain-containing protein. (1106 aa)
BUB1BUB1 mitotic checkpoint serine/threonine kinase. (1071 aa)
NUP85Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (655 aa)
XRCC1X-ray repair cross complementing 1. (630 aa)
DNMT3ADNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (912 aa)
THOC3THO complex 3. (351 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (326 aa)
CENPCCentromere protein C. (929 aa)
ORC2Origin recognition complex subunit 2. (577 aa)
CHEK2Checkpoint kinase 2. (530 aa)
LRWD1Leucine rich repeats and WD repeat domain containing 1. (601 aa)
TEP1Telomerase associated protein 1. (2614 aa)
ENSUAMP00000014202Uncharacterized protein. (81 aa)
ENSUAMP00000014243Histone H2B; Belongs to the histone H2B family. (126 aa)
SPC24SPC24 component of NDC80 kinetochore complex. (201 aa)
ORC4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa)
ZNF618Zinc finger protein 618. (944 aa)
MIS12MIS12 kinetochore complex component. (212 aa)
ENSUAMP00000015206Uncharacterized protein. (392 aa)
CHMP5Charged multivesicular body protein 5. (219 aa)
PMLPromyelocytic leukemia. (877 aa)
CBX3Chromobox 3. (183 aa)
DCTN2Dynactin subunit 2. (422 aa)
NGDNNeuroguidin. (318 aa)
CDCA5Cell division cycle associated 5. (253 aa)
MIS18AMIS18 kinetochore protein A. (237 aa)
ENSUAMP00000015392Uncharacterized protein. (1523 aa)
WDR82WD repeat domain 82. (313 aa)
ENSUAMP00000016108Uncharacterized protein. (92 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)
TNKSPoly [ADP-ribose] polymerase. (908 aa)
MACROH2A1Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (371 aa)
ENSUAMP00000017193Uncharacterized protein. (91 aa)
THOC5THO complex 5. (660 aa)
ENSUAMP00000017329Uncharacterized protein. (205 aa)
ZWINTZW10 interacting kinetochore protein. (286 aa)
SKA2Spindle and kinetochore associated complex subunit 2. (117 aa)
CENPPCentromere protein P. (276 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1117 aa)
ENSUAMP00000017773CAF1C_H4-bd domain-containing protein. (87 aa)
GAR1H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (192 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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