STRINGSTRING
ENSUAMP00000036878 ENSUAMP00000036878 ENSUAMP00000037086 ENSUAMP00000037086 PDHA2 PDHA2 NDUFA6 NDUFA6 DLAT DLAT ETFB ETFB IDH3A IDH3A ENSUAMP00000023210 ENSUAMP00000023210 NDUFV2 NDUFV2 NDUFB7 NDUFB7 NCF2 NCF2 DBT DBT NDUFA8 NDUFA8 P4HB P4HB NDUFAB1 NDUFAB1 ENSUAMP00000020992 ENSUAMP00000020992 IDH3G IDH3G NDUFS3 NDUFS3 UQCRB UQCRB ENSUAMP00000000384 ENSUAMP00000000384 NDUFV3 NDUFV3 ENSUAMP00000001521 ENSUAMP00000001521 ENSUAMP00000002141 ENSUAMP00000002141 ENSUAMP00000002193 ENSUAMP00000002193 ENSUAMP00000003048 ENSUAMP00000003048 ENSUAMP00000003276 ENSUAMP00000003276 GMPR GMPR ENSUAMP00000004451 ENSUAMP00000004451 GLDC GLDC NCF4 NCF4 ENSUAMP00000005938 ENSUAMP00000005938 NDUFB4 NDUFB4 FOXRED1 FOXRED1 NDUFA2 NDUFA2 ENSUAMP00000006504 ENSUAMP00000006504 IDH3B IDH3B ENSUAMP00000007782 ENSUAMP00000007782 ENSUAMP00000007991 ENSUAMP00000007991 ENSUAMP00000008092 ENSUAMP00000008092 BCKDHB BCKDHB CAT CAT NCF1 NCF1 BCKDK BCKDK ENSUAMP00000011085 ENSUAMP00000011085 ENSUAMP00000011699 ENSUAMP00000011699 ENSUAMP00000012006 ENSUAMP00000012006 NDUFV1 NDUFV1 DMAC2 DMAC2 ENSUAMP00000012476 ENSUAMP00000012476 ENSUAMP00000012538 ENSUAMP00000012538 ENSUAMP00000012541 ENSUAMP00000012541 ENSUAMP00000012629 ENSUAMP00000012629 DLD DLD ENSUAMP00000014276 ENSUAMP00000014276 NDUFC1 NDUFC1 ENSUAMP00000014708 ENSUAMP00000014708 ENSUAMP00000014859 ENSUAMP00000014859 ENSUAMP00000016658 ENSUAMP00000016658 ENSUAMP00000017059 ENSUAMP00000017059 OGDHL OGDHL UQCR10 UQCR10 ENSUAMP00000019572 ENSUAMP00000019572 NOXA1 NOXA1 ENSUAMP00000018569 ENSUAMP00000018569 NDUFS7 NDUFS7 ENSUAMP00000018005 ENSUAMP00000018005 OGDH OGDH ENSUAMP00000017612 ENSUAMP00000017612 ENSUAMP00000017600 ENSUAMP00000017600 GPD1 GPD1 ENSUAMP00000023721 ENSUAMP00000023721 UQCRC1 UQCRC1 NDUFB2 NDUFB2 NOXO1 NOXO1 NDUFB10 NDUFB10 ENSUAMP00000024903 ENSUAMP00000024903 ENSUAMP00000024931 ENSUAMP00000024931 MRPS36 MRPS36 CBR4 CBR4 ENSUAMP00000025782 ENSUAMP00000025782 NDUFB6 NDUFB6 PDHX PDHX ENSUAMP00000027510 ENSUAMP00000027510 ENSUAMP00000027773 ENSUAMP00000027773 RRM2 RRM2 NOX3 NOX3 ENSUAMP00000028021 ENSUAMP00000028021 ENSUAMP00000028798 ENSUAMP00000028798 ENSUAMP00000028954 ENSUAMP00000028954 ENSUAMP00000029474 ENSUAMP00000029474 ENSUAMP00000029554 ENSUAMP00000029554 ENSUAMP00000029622 ENSUAMP00000029622 NDUFS4 NDUFS4 NDUFA10 NDUFA10 ENSUAMP00000030397 ENSUAMP00000030397 ENSUAMP00000030544 ENSUAMP00000030544 ENSUAMP00000030699 ENSUAMP00000030699 UQCRFS1 UQCRFS1 ENSUAMP00000030923 ENSUAMP00000030923 ENSUAMP00000030994 ENSUAMP00000030994 ENSUAMP00000031664 ENSUAMP00000031664 PDK1 PDK1 KAT2A KAT2A PDHA1 PDHA1 GMPR2 GMPR2 SDHB SDHB ENSUAMP00000032116 ENSUAMP00000032116 ENSUAMP00000032194 ENSUAMP00000032194 XK XK CYBB CYBB DUOX1 DUOX1 DUOX2 DUOX2 GPD2 GPD2 ETFA ETFA ENSUAMP00000032762 ENSUAMP00000032762 ENSUAMP00000033248 ENSUAMP00000033248 ENSUAMP00000033338 ENSUAMP00000033338 ENSUAMP00000033428 ENSUAMP00000033428 NDUFS2 NDUFS2 UQCC3 UQCC3 UQCRQ UQCRQ NDUFB11 NDUFB11 ENSUAMP00000034251 ENSUAMP00000034251 CYB5R3 CYB5R3 ENSUAMP00000034778 ENSUAMP00000034778 NOX1 NOX1 ENSUAMP00000035339 ENSUAMP00000035339 PDK2 PDK2 HSD17B8 HSD17B8 PDHB PDHB ENSUAMP00000035973 ENSUAMP00000035973 CYC1 CYC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSUAMP00000036878Uncharacterized protein. (61 aa)
ENSUAMP00000037086Uncharacterized protein. (118 aa)
PDHA2Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (391 aa)
NDUFA6NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (128 aa)
DLATAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (647 aa)
ETFBElectron transfer flavoprotein subunit beta. (255 aa)
IDH3AIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (380 aa)
ENSUAMP00000023210Uncharacterized protein. (196 aa)
NDUFV2NADH:ubiquinone oxidoreductase core subunit V2. (249 aa)
NDUFB7NADH:ubiquinone oxidoreductase subunit B7. (137 aa)
NCF2Neutrophil cytosolic factor 2. (517 aa)
DBTDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (482 aa)
NDUFA8NADH:ubiquinone oxidoreductase subunit A8. (144 aa)
P4HBProtein disulfide-isomerase. (510 aa)
NDUFAB1Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (154 aa)
ENSUAMP00000020992ATP-cone domain-containing protein. (123 aa)
IDH3GIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (395 aa)
NDUFS3NADH:ubiquinone oxidoreductase core subunit S3; Belongs to the complex I 30 kDa subunit family. (337 aa)
UQCRBCytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. (111 aa)
ENSUAMP00000000384NAD_binding_6 domain-containing protein. (147 aa)
NDUFV3NADH:ubiquinone oxidoreductase subunit V3. (435 aa)
ENSUAMP00000001521Lipoyl-binding domain-containing protein. (129 aa)
ENSUAMP00000002141Uncharacterized protein. (70 aa)
ENSUAMP00000002193Uncharacterized protein; Belongs to the complex I LYR family. (224 aa)
ENSUAMP00000003048Uncharacterized protein. (94 aa)
ENSUAMP00000003276Uncharacterized protein. (80 aa)
GMPRGMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (291 aa)
ENSUAMP00000004451IMPDH domain-containing protein. (161 aa)
GLDCGlycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (991 aa)
NCF4Neutrophil cytosolic factor 4. (338 aa)
ENSUAMP00000005938Uncharacterized protein. (84 aa)
NDUFB4NADH:ubiquinone oxidoreductase subunit B4. (129 aa)
FOXRED1FAD dependent oxidoreductase domain containing 1. (486 aa)
NDUFA2NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (99 aa)
ENSUAMP00000006504Uncharacterized protein. (101 aa)
IDH3BIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (385 aa)
ENSUAMP00000007782Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (156 aa)
ENSUAMP00000007991Uncharacterized protein. (97 aa)
ENSUAMP00000008092Uncharacterized protein. (70 aa)
BCKDHBBranched chain keto acid dehydrogenase E1 subunit beta. (318 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa)
NCF1Neutrophil cytosolic factor 1. (396 aa)
BCKDKProtein-serine/threonine kinase. (412 aa)
ENSUAMP00000011085Uncharacterized protein. (53 aa)
ENSUAMP00000011699NAD_Gly3P_dh_C domain-containing protein. (117 aa)
ENSUAMP00000012006Uncharacterized protein. (255 aa)
NDUFV1NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (464 aa)
DMAC2Distal membrane arm assembly complex 2. (289 aa)
ENSUAMP000000124762-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (466 aa)
ENSUAMP000000125382-oxoacid_dh domain-containing protein. (170 aa)
ENSUAMP00000012541Uncharacterized protein. (98 aa)
ENSUAMP00000012629Uncharacterized protein. (211 aa)
DLDDihydrolipoyl dehydrogenase. (509 aa)
ENSUAMP00000014276Uncharacterized protein. (118 aa)
NDUFC1NADH:ubiquinone oxidoreductase subunit C1. (76 aa)
ENSUAMP00000014708UCR_hinge domain-containing protein. (100 aa)
ENSUAMP00000014859Iso_dh domain-containing protein. (372 aa)
ENSUAMP00000016658Uncharacterized protein. (84 aa)
ENSUAMP000000170592-oxoacid_dh domain-containing protein. (248 aa)
OGDHLOxoglutarate dehydrogenase like. (1025 aa)
UQCR10Ubiquinol-cytochrome c reductase, complex III subunit X. (64 aa)
ENSUAMP00000019572Uncharacterized protein. (112 aa)
NOXA1NADPH oxidase activator 1. (467 aa)
ENSUAMP00000018569Uncharacterized protein. (56 aa)
NDUFS7NADH:ubiquinone oxidoreductase core subunit S7; Belongs to the complex I 20 kDa subunit family. (216 aa)
ENSUAMP00000018005Uncharacterized protein. (86 aa)
OGDHOxoglutarate dehydrogenase. (1083 aa)
ENSUAMP00000017612zf-CHCC domain-containing protein. (117 aa)
ENSUAMP00000017600Uncharacterized protein. (136 aa)
GPD1Glycerol-3-phosphate dehydrogenase [NAD(+)]. (349 aa)
ENSUAMP00000023721Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (159 aa)
UQCRC1Ubiquinol-cytochrome c reductase core protein 1. (481 aa)
NDUFB2NADH:ubiquinone oxidoreductase subunit B2. (105 aa)
NOXO1NADPH oxidase organizer 1. (391 aa)
NDUFB10NADH:ubiquinone oxidoreductase subunit B10. (176 aa)
ENSUAMP00000024903Uncharacterized protein. (210 aa)
ENSUAMP00000024931Uncharacterized protein. (162 aa)
MRPS36Mitochondrial ribosomal protein S36. (102 aa)
CBR4Carbonyl reductase 4. (237 aa)
ENSUAMP00000025782Uncharacterized protein. (257 aa)
NDUFB6NADH:ubiquinone oxidoreductase subunit B6. (97 aa)
PDHXDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (501 aa)
ENSUAMP00000027510zf-CHCC domain-containing protein. (124 aa)
ENSUAMP00000027773Uncharacterized protein. (116 aa)
RRM2Ribonucleotide reductase regulatory subunit M2. (297 aa)
NOX3NADPH oxidase 3. (567 aa)
ENSUAMP00000028021Uncharacterized protein. (135 aa)
ENSUAMP00000028798Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (665 aa)
ENSUAMP00000028954Uncharacterized protein. (177 aa)
ENSUAMP00000029474Uncharacterized protein. (141 aa)
ENSUAMP00000029554Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (159 aa)
ENSUAMP00000029622Uncharacterized protein. (173 aa)
NDUFS4NADH:ubiquinone oxidoreductase subunit S4. (175 aa)
NDUFA10NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (355 aa)
ENSUAMP00000030397NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (145 aa)
ENSUAMP00000030544NADH dehydrogenase [ubiquinone] 1 subunit C2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (120 aa)
ENSUAMP00000030699NAD_Gly3P_dh_N domain-containing protein. (180 aa)
UQCRFS1Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (274 aa)
ENSUAMP00000030923annotation not available (80 aa)
ENSUAMP00000030994Uncharacterized protein. (72 aa)
ENSUAMP00000031664annotation not available (372 aa)
PDK1Protein-serine/threonine kinase. (438 aa)
KAT2AHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa)
PDHA1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (390 aa)
GMPR2GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (348 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (254 aa)
ENSUAMP00000032116Uncharacterized protein. (70 aa)
ENSUAMP00000032194Uncharacterized protein. (104 aa)
XKXK-related protein. (433 aa)
CYBBCytochrome b-245 beta chain. (570 aa)
DUOX1Dual oxidase 1. (1539 aa)
DUOX2Dual oxidase 2. (1531 aa)
GPD2Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (699 aa)
ETFAElectron transfer flavoprotein subunit alpha. (333 aa)
ENSUAMP00000032762Uncharacterized protein. (81 aa)
ENSUAMP00000033248Uncharacterized protein. (198 aa)
ENSUAMP00000033338NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (98 aa)
ENSUAMP00000033428Uncharacterized protein. (169 aa)
NDUFS2NADH:ubiquinone oxidoreductase core subunit S2; Belongs to the complex I 49 kDa subunit family. (533 aa)
UQCC3Ubiquinol-cytochrome c reductase complex assembly factor 3. (89 aa)
UQCRQUbiquinol-cytochrome c reductase complex III subunit VII. (82 aa)
NDUFB11NADH:ubiquinone oxidoreductase subunit B11. (154 aa)
ENSUAMP00000034251Uncharacterized protein. (66 aa)
CYB5R3NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (301 aa)
ENSUAMP00000034778Uncharacterized protein. (361 aa)
NOX1NADPH oxidase 1. (594 aa)
ENSUAMP00000035339Uncharacterized protein. (80 aa)
PDK2Protein-serine/threonine kinase. (249 aa)
HSD17B8Hydroxysteroid 17-beta dehydrogenase 8. (259 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (359 aa)
ENSUAMP00000035973Uncharacterized protein. (76 aa)
CYC1Cytochrome c1. (325 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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