STRINGSTRING
B4GALT1 B4GALT1 HOXD13 HOXD13 NR5A1 NR5A1 ENSUAMP00000033485 ENSUAMP00000033485 TCP11 TCP11 UNC5C UNC5C SOX9 SOX9 OVOL1 OVOL1 ENSUAMP00000026963 ENSUAMP00000026963 IQCF1 IQCF1 IQCF5 IQCF5 ENSUAMP00000027032 ENSUAMP00000027032 ENSUAMP00000027033 ENSUAMP00000027033 FBXO43 FBXO43 SULF1 SULF1 RNASE10 RNASE10 ENSUAMP00000028309 ENSUAMP00000028309 ENSUAMP00000028310 ENSUAMP00000028310 ENSUAMP00000028577 ENSUAMP00000028577 ENSUAMP00000028583 ENSUAMP00000028583 BHMG1 BHMG1 CCR6 CCR6 BMP4 BMP4 ENSUAMP00000029157 ENSUAMP00000029157 NANOS2 NANOS2 PTGDR2 PTGDR2 CDC25A CDC25A STXBP1 STXBP1 TACR1 TACR1 ENSUAMP00000000133 ENSUAMP00000000133 ENSUAMP00000000421 ENSUAMP00000000421 MSX1 MSX1 LFNG LFNG CDC20 CDC20 ENSUAMP00000001430 ENSUAMP00000001430 ENSUAMP00000001445 ENSUAMP00000001445 ENSUAMP00000001461 ENSUAMP00000001461 ENSUAMP00000001661 ENSUAMP00000001661 ARHGDIB ARHGDIB PRDX4 PRDX4 ENSUAMP00000001879 ENSUAMP00000001879 MEIOC MEIOC SYCE3 SYCE3 ENSUAMP00000002265 ENSUAMP00000002265 RAD51AP1 RAD51AP1 NPM2 NPM2 VIP VIP FBXO42 FBXO42 ENSUAMP00000003848 ENSUAMP00000003848 SFRP1 SFRP1 DHX37 DHX37 FGF9 FGF9 ENSUAMP00000004918 ENSUAMP00000004918 CFAP69 CFAP69 ENSUAMP00000005628 ENSUAMP00000005628 ENSUAMP00000005720 ENSUAMP00000005720 ZP2 ZP2 ESR1 ESR1 ENSUAMP00000006800 ENSUAMP00000006800 ZP4 ZP4 INHBA INHBA CDKN1B CDKN1B PLAT PLAT LIF LIF TTK TTK GCM1 GCM1 GLRA1 GLRA1 NODAL NODAL FBXO5 FBXO5 PLA2G10 PLA2G10 PHLDA2 PHLDA2 ENSUAMP00000010431 ENSUAMP00000010431 GPR3 GPR3 YTHDF2 YTHDF2 CHFR CHFR NPR2 NPR2 CCDC36 CCDC36 NUPR1 NUPR1 HORMAD1 HORMAD1 TEX101 TEX101 EAF2 EAF2 AGO2 AGO2 LHFPL2 LHFPL2 SIRT2 SIRT2 ASTL ASTL ZP1 ZP1 ENSUAMP00000014099 ENSUAMP00000014099 ENSUAMP00000015168 ENSUAMP00000015168 YTHDF3 YTHDF3 MAPK15 MAPK15 OOEP OOEP ENSUAMP00000016192 ENSUAMP00000016192 CACNA1H CACNA1H CNTD1 CNTD1 ENSUAMP00000016615 ENSUAMP00000016615 SYCP2 SYCP2 SMURF2 SMURF2 GJA1 GJA1 ACVR1B ACVR1B WEE2 WEE2 WDR77 WDR77 CCDC87 CCDC87 FAM170B FAM170B KIT KIT ENSUAMP00000018907 ENSUAMP00000018907 TRIP13 TRIP13 ZFPM2 ZFPM2 TACR3 TACR3 TACR2 TACR2 SERPINF1 SERPINF1 ENSUAMP00000019810 ENSUAMP00000019810 YBX3 YBX3 BNC1 BNC1 PDE3A PDE3A ENSUAMP00000021520 ENSUAMP00000021520 FZR1 FZR1 ADA ADA STK4 STK4 ACVR1C ACVR1C DDB1 DDB1 CITED2 CITED2 PRSS37 PRSS37 MAEL MAEL AURKA AURKA CIB1 CIB1 HYAL3 HYAL3 ENSUAMP00000037141 ENSUAMP00000037141 SPATA22 SPATA22 STRA8 STRA8 SYDE1 SYDE1 CDC25B CDC25B FANCA FANCA PRDM14 PRDM14 SNAI1 SNAI1 JAG1 JAG1 MOS MOS NOTCH1 NOTCH1 ENSUAMP00000034140 ENSUAMP00000034140
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
B4GALT1Beta-1,4-galactosyltransferase 1. (400 aa)
HOXD13Homeobox D13. (333 aa)
NR5A1Nuclear receptor subfamily 5 group A member 1. (461 aa)
ENSUAMP00000033485ZP domain-containing protein. (405 aa)
TCP11T-complex 11. (519 aa)
UNC5CUnc-5 netrin receptor C. (927 aa)
SOX9SRY-box transcription factor 9. (484 aa)
OVOL1Ovo like transcriptional repressor 1. (247 aa)
ENSUAMP00000026963Protein kinase domain-containing protein. (93 aa)
IQCF1IQ motif containing F1. (203 aa)
IQCF5IQ motif containing F5. (135 aa)
ENSUAMP00000027032Uncharacterized protein. (146 aa)
ENSUAMP00000027033Uncharacterized protein. (145 aa)
FBXO43F-box protein 43. (687 aa)
SULF1Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (940 aa)
RNASE10Ribonuclease A family member 10 (inactive); Belongs to the pancreatic ribonuclease family. (214 aa)
ENSUAMP00000028309Uncharacterized protein. (214 aa)
ENSUAMP00000028310DM domain-containing protein. (221 aa)
ENSUAMP00000028577Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1824 aa)
ENSUAMP00000028583Myosin N-terminal SH3-like domain-containing protein. (135 aa)
BHMG1Basic helix-loop-helix and HMG-box containing 1. (565 aa)
CCR6C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (381 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
ENSUAMP00000029157Uncharacterized protein. (281 aa)
NANOS2Nanos C2HC-type zinc finger 2; Belongs to the nanos family. (138 aa)
PTGDR2Prostaglandin D2 receptor 2; Belongs to the G-protein coupled receptor 1 family. (386 aa)
CDC25ACell division cycle 25A. (498 aa)
STXBP1Syntaxin binding protein 1; Belongs to the STXBP/unc-18/SEC1 family. (580 aa)
TACR1Tachykinin receptor 1; Belongs to the G-protein coupled receptor 1 family. (407 aa)
ENSUAMP00000000133Uncharacterized protein. (193 aa)
ENSUAMP00000000421NTR domain-containing protein. (132 aa)
MSX1Msh homeobox 1. (303 aa)
LFNGLFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase. (251 aa)
CDC20Cell division cycle 20. (516 aa)
ENSUAMP00000001430Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (180 aa)
ENSUAMP00000001445Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (181 aa)
ENSUAMP00000001461Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (164 aa)
ENSUAMP00000001661TGF_BETA_2 domain-containing protein. (194 aa)
ARHGDIBRho GDP dissociation inhibitor beta. (200 aa)
PRDX4Peroxiredoxin 4. (272 aa)
ENSUAMP00000001879Protein kinase domain-containing protein. (335 aa)
MEIOCMeiosis specific with coiled-coil domain. (960 aa)
SYCE3Synaptonemal complex central element protein 3. (88 aa)
ENSUAMP00000002265Uncharacterized protein. (503 aa)
RAD51AP1RAD51 associated protein 1. (336 aa)
NPM2Nucleophosmin/nucleoplasmin 2. (261 aa)
VIPVasoactive intestinal peptide. (170 aa)
FBXO42F-box protein 42. (401 aa)
ENSUAMP00000003848Uncharacterized protein. (142 aa)
SFRP1Secreted frizzled related protein 1. (337 aa)
DHX37DEAH-box helicase 37. (1149 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
ENSUAMP00000004918Homeobox domain-containing protein. (230 aa)
CFAP69Cilia and flagella associated protein 69. (629 aa)
ENSUAMP00000005628SH2 domain-containing protein. (508 aa)
ENSUAMP00000005720Piwi domain-containing protein. (184 aa)
ZP2Zona pellucida glycoprotein 2. (702 aa)
ESR1Estrogen receptor 1. (490 aa)
ENSUAMP00000006800Uncharacterized protein. (97 aa)
ZP4Zona pellucida glycoprotein 4. (568 aa)
INHBAInhibin subunit beta A. (424 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (200 aa)
PLATPlasminogen activator; Belongs to the peptidase S1 family. (563 aa)
LIFLIF interleukin 6 family cytokine. (202 aa)
TTKTTK protein kinase. (853 aa)
GCM1Glial cells missing transcription factor 1. (435 aa)
GLRA1Glycine receptor alpha 1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (472 aa)
NODALNodal growth differentiation factor. (348 aa)
FBXO5F-box protein 5. (448 aa)
PLA2G10Phospholipase A(2). (157 aa)
PHLDA2Pleckstrin homology like domain family A member 2. (131 aa)
ENSUAMP00000010431Uncharacterized protein. (415 aa)
GPR3G protein-coupled receptor 3; Belongs to the G-protein coupled receptor 1 family. (330 aa)
YTHDF2YTH N6-methyladenosine RNA binding protein 2. (580 aa)
CHFRCheckpoint with forkhead and ring finger domains. (648 aa)
NPR2Guanylate cyclase. (1048 aa)
CCDC36Coiled-coil domain containing 36. (559 aa)
NUPR1Nuclear protein 1, transcriptional regulator. (82 aa)
HORMAD1HORMA domain containing 1. (390 aa)
TEX101Testis expressed 101. (243 aa)
EAF2ELL associated factor 2. (249 aa)
AGO2Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (911 aa)
LHFPL2LHFPL tetraspan subfamily member 2. (219 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (426 aa)
ASTLMetalloendopeptidase. (424 aa)
ZP1Zona pellucida glycoprotein 1. (623 aa)
ENSUAMP00000014099ZP domain-containing protein. (417 aa)
ENSUAMP00000015168Uncharacterized protein. (119 aa)
YTHDF3YTH N6-methyladenosine RNA binding protein 3. (588 aa)
MAPK15Mitogen-activated protein kinase. (680 aa)
OOEPOocyte expressed protein. (156 aa)
ENSUAMP00000016192Integrin beta; Belongs to the integrin beta chain family. (786 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (2205 aa)
CNTD1Cyclin N-terminal domain containing 1. (331 aa)
ENSUAMP00000016615Uncharacterized protein. (147 aa)
SYCP2Synaptonemal complex protein 2. (1469 aa)
SMURF2E3 ubiquitin-protein ligase. (736 aa)
GJA1Gap junction alpha-1 protein; Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli a [...] (382 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (505 aa)
WEE2Wee1-like protein kinase. (530 aa)
WDR77WD repeat domain 77. (342 aa)
CCDC87Coiled-coil domain containing 87. (861 aa)
FAM170BFamily with sequence similarity 170 member B. (286 aa)
KITKIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (999 aa)
ENSUAMP00000018907Uncharacterized protein. (888 aa)
TRIP13Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family. (432 aa)
ZFPM2Zinc finger protein, FOG family member 2. (1193 aa)
TACR3Tachykinin receptor 3; Belongs to the G-protein coupled receptor 1 family. (460 aa)
TACR2Tachykinin receptor 2; Belongs to the G-protein coupled receptor 1 family. (383 aa)
SERPINF1Serpin family F member 1; Belongs to the serpin family. (418 aa)
ENSUAMP00000019810Uncharacterized protein. (884 aa)
YBX3Y-box binding protein 3. (273 aa)
BNC1Basonuclin 1. (1021 aa)
PDE3APhosphodiesterase. (777 aa)
ENSUAMP00000021520Uncharacterized protein. (210 aa)
FZR1Fizzy and cell division cycle 20 related 1. (493 aa)
ADAAdenosine deaminase. (385 aa)
STK4Serine/threonine kinase 4. (487 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (494 aa)
DDB1Damage specific DNA binding protein 1. (1151 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa)
PRSS37Serine protease 37. (236 aa)
MAELMaelstrom spermatogenic transposon silencer. (434 aa)
AURKAAurora kinase A; Belongs to the protein kinase superfamily. (405 aa)
CIB1Calcium and integrin binding 1. (191 aa)
HYAL3Hyaluronidase. (417 aa)
ENSUAMP00000037141Uncharacterized protein. (54 aa)
SPATA22Spermatogenesis associated 22. (362 aa)
STRA8Stimulated by retinoic acid 8. (372 aa)
SYDE1Synapse defective Rho GTPase homolog 1. (735 aa)
CDC25BCell division cycle 25B. (559 aa)
FANCAFA complementation group A. (1441 aa)
PRDM14PR/SET domain 14. (566 aa)
SNAI1Snail family transcriptional repressor 1. (259 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1226 aa)
MOSMOS proto-oncogene, serine/threonine kinase; Belongs to the protein kinase superfamily. (349 aa)
NOTCH1Notch receptor 1. (2547 aa)
ENSUAMP00000034140Uncharacterized protein. (256 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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