40 items (Ursus americanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FBXL15	F-box and leucine rich repeat protein 15. (300 aa)
	FBXO9	F-box protein 9. (435 aa)
	USP47	Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1275 aa)
	FBXL6	F-box and leucine rich repeat protein 6. (533 aa)
	TMEM183A	Transmembrane protein 183A. (376 aa)
	FBH1	F-box DNA helicase 1. (1046 aa)
	ENSUAMP00000004242	Uncharacterized protein. (138 aa)
	FBXO42	F-box protein 42. (401 aa)
	FBXW5	F-box and WD repeat domain containing 5. (725 aa)
	NCBP3	Nuclear cap binding subunit 3. (630 aa)
	CKS1B	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
	FBXO31	F-box protein 31. (542 aa)
	LRRC29	Leucine rich repeat containing 29. (166 aa)
	CKS2	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (74 aa)
	FBXL14	F-box and leucine rich repeat protein 14. (420 aa)
	FBXO2	F-box protein 2. (294 aa)
	ENSUAMP00000017316	F-box domain-containing protein. (71 aa)
	SKP2	S-phase kinase associated protein 2. (436 aa)
	ZC3HC1	Zinc finger C3HC-type containing 1. (502 aa)
	FBXL3	F-box and leucine rich repeat protein 3. (428 aa)
	FBXO4	F-box protein 4. (303 aa)
	FBXL7	F-box and leucine rich repeat protein 7. (457 aa)
	ENSUAMP00000027679	Uncharacterized protein. (51 aa)
	FBXO27	F-box protein 27. (279 aa)
	FBXL2	F-box and leucine rich repeat protein 2. (422 aa)
	CUL1	Cullin 1; Belongs to the cullin family. (742 aa)
	ENSUAMP00000029036	Uncharacterized protein. (233 aa)
	FBXL5	F-box and leucine rich repeat protein 5. (691 aa)
	ENSUAMP00000033960	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (58 aa)
	FBXO33	F-box protein 33. (556 aa)
	RBX1	Ring-box 1. (108 aa)
	BTRC	Beta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
	FBXL19	F-box and leucine rich repeat protein 19. (703 aa)
	ENSUAMP00000031825	FBA domain-containing protein. (158 aa)
	FBXW11	F-box and WD repeat domain containing 11. (543 aa)
	CCNF	Cyclin F; Belongs to the cyclin family. (776 aa)
	FBXO17	F-box protein 17. (277 aa)
	FBXO25	F-box protein 25. (366 aa)
	ENSUAMP00000010403	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (66 aa)
	FBXL17	F-box and leucine rich repeat protein 17. (662 aa)

Your Current Organism:

Ursus americanus

NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BTRC	CCNF	ENSUAMP00000031418	ENSUAMP00000016434	Beta-transducin repeat containing E3 ubiquitin protein ligase.	Cyclin F; Belongs to the cyclin family.	0.426
BTRC	CUL1	ENSUAMP00000031418	ENSUAMP00000028874	Beta-transducin repeat containing E3 ubiquitin protein ligase.	Cullin 1; Belongs to the cullin family.	0.987
BTRC	ENSUAMP00000027679	ENSUAMP00000031418	ENSUAMP00000027679	Beta-transducin repeat containing E3 ubiquitin protein ligase.	Uncharacterized protein.	0.987
BTRC	FBXO2	ENSUAMP00000031418	ENSUAMP00000024523	Beta-transducin repeat containing E3 ubiquitin protein ligase.	F-box protein 2.	0.959
BTRC	FBXO4	ENSUAMP00000031418	ENSUAMP00000000932	Beta-transducin repeat containing E3 ubiquitin protein ligase.	F-box protein 4.	0.950
BTRC	FBXW11	ENSUAMP00000031418	ENSUAMP00000032203	Beta-transducin repeat containing E3 ubiquitin protein ligase.	F-box and WD repeat domain containing 11.	0.986
BTRC	RBX1	ENSUAMP00000031418	ENSUAMP00000030890	Beta-transducin repeat containing E3 ubiquitin protein ligase.	Ring-box 1.	0.995
BTRC	SKP2	ENSUAMP00000031418	ENSUAMP00000025997	Beta-transducin repeat containing E3 ubiquitin protein ligase.	S-phase kinase associated protein 2.	0.969
BTRC	USP47	ENSUAMP00000031418	ENSUAMP00000007347	Beta-transducin repeat containing E3 ubiquitin protein ligase.	Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family.	0.593
CCNF	BTRC	ENSUAMP00000016434	ENSUAMP00000031418	Cyclin F; Belongs to the cyclin family.	Beta-transducin repeat containing E3 ubiquitin protein ligase.	0.426
CCNF	CKS1B	ENSUAMP00000016434	ENSUAMP00000018064	Cyclin F; Belongs to the cyclin family.	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	0.605
CCNF	CKS2	ENSUAMP00000016434	ENSUAMP00000020627	Cyclin F; Belongs to the cyclin family.	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	0.605
CCNF	CUL1	ENSUAMP00000016434	ENSUAMP00000028874	Cyclin F; Belongs to the cyclin family.	Cullin 1; Belongs to the cullin family.	0.839
CCNF	ENSUAMP00000010403	ENSUAMP00000016434	ENSUAMP00000010403	Cyclin F; Belongs to the cyclin family.	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	0.605
CCNF	ENSUAMP00000027679	ENSUAMP00000016434	ENSUAMP00000027679	Cyclin F; Belongs to the cyclin family.	Uncharacterized protein.	0.839
CCNF	ENSUAMP00000033960	ENSUAMP00000016434	ENSUAMP00000033960	Cyclin F; Belongs to the cyclin family.	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	0.605
CCNF	RBX1	ENSUAMP00000016434	ENSUAMP00000030890	Cyclin F; Belongs to the cyclin family.	Ring-box 1.	0.708
CCNF	SKP2	ENSUAMP00000016434	ENSUAMP00000025997	Cyclin F; Belongs to the cyclin family.	S-phase kinase associated protein 2.	0.842
CKS1B	CCNF	ENSUAMP00000018064	ENSUAMP00000016434	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	Cyclin F; Belongs to the cyclin family.	0.605
CKS1B	CUL1	ENSUAMP00000018064	ENSUAMP00000028874	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	Cullin 1; Belongs to the cullin family.	0.872