STRINGSTRING
TFEC TFEC TCF12 TCF12 OLIG3 OLIG3 NEUROG3 NEUROG3 TAL2 TAL2 BHLHA15 BHLHA15 HAND1 HAND1 TCF21 TCF21 NCOA3 NCOA3 ATOH7 ATOH7 HEY1 HEY1 NHLH2 NHLH2 BHMG1 BHMG1 ENSUAMP00000028801 ENSUAMP00000028801 TCF4 TCF4 MGA MGA ARNTL ARNTL ASCL4 ASCL4 LYL1 LYL1 MITF MITF ID3 ID3 ID1 ID1 ASCL2 ASCL2 MYC MYC HES3 HES3 ARNT2 ARNT2 MNT MNT USF1 USF1 NPAS1 NPAS1 HIF1A HIF1A USF3 USF3 TFE3 TFE3 ENSUAMP00000035193 ENSUAMP00000035193 NCOA2 NCOA2 NPAS4 NPAS4 ENSUAMP00000036303 ENSUAMP00000036303 SCX SCX MXD3 MXD3 MYOD1 MYOD1 OLIG2 OLIG2 MESP2 MESP2 TFAP4 TFAP4 ENSUAMP00000006139 ENSUAMP00000006139 HES7 HES7 HIF3A HIF3A NEUROG2 NEUROG2 NEUROD4 NEUROD4 NEUROD6 NEUROD6 FERD3L FERD3L ID2 ID2 MSGN1 MSGN1 ENSUAMP00000001356 ENSUAMP00000001356 MYCL MYCL HEYL HEYL MXD1 MXD1 SIM1 SIM1 SIM2 SIM2 MYOG MYOG HAND2 HAND2 SREBF2 SREBF2 ENSUAMP00000007797 ENSUAMP00000007797 NPAS2 NPAS2 TCF23 TCF23 MYF6 MYF6 MYF5 MYF5 MLXIPL MLXIPL ENSUAMP00000021070 ENSUAMP00000021070 MSC MSC NEUROD2 NEUROD2 USF2 USF2 ATOH1 ATOH1 ENSUAMP00000018971 ENSUAMP00000018971 TCF3 TCF3 NEUROG1 NEUROG1 MAX MAX HES6 HES6 HELT HELT NHLH1 NHLH1 ATOH8 ATOH8 TFEB TFEB SREBF1 SREBF1 ASCL3 ASCL3 TWIST2 TWIST2 MXD4 MXD4 MLXIP MLXIP EPAS1 EPAS1 ENSUAMP00000010461 ENSUAMP00000010461 HEY2 HEY2 FIGLA FIGLA ASCL1 ASCL1 MXI1 MXI1 HES1 HES1 ENSUAMP00000009330 ENSUAMP00000009330 MLX MLX NCOA1 NCOA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TFECTranscription factor EC. (280 aa)
TCF12Transcription factor 12. (632 aa)
OLIG3Oligodendrocyte transcription factor 3. (272 aa)
NEUROG3Neurogenin 3. (215 aa)
TAL2TAL bHLH transcription factor 2. (137 aa)
BHLHA15Basic helix-loop-helix family member a15. (187 aa)
HAND1Heart and neural crest derivatives expressed 1. (218 aa)
TCF21Transcription factor 21. (179 aa)
NCOA3Nuclear receptor coactivator. (1431 aa)
ATOH7Atonal bHLH transcription factor 7. (149 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
NHLH2Nescient helix-loop-helix 2. (135 aa)
BHMG1Basic helix-loop-helix and HMG-box containing 1. (565 aa)
ENSUAMP00000028801BHLH domain-containing protein. (234 aa)
TCF4Transcription factor 4. (581 aa)
MGAMAX dimerization protein MGA. (3115 aa)
ARNTLAryl hydrocarbon receptor nuclear translocator like. (626 aa)
ASCL4Achaete-scute family bHLH transcription factor 4. (172 aa)
LYL1LYL1 basic helix-loop-helix family member. (280 aa)
MITFMelanocyte inducing transcription factor. (525 aa)
ID3Inhibitor of DNA binding 3, HLH protein. (119 aa)
ID1Inhibitor of DNA binding 1, HLH protein. (154 aa)
ASCL2Achaete-scute family bHLH transcription factor 2. (194 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa)
HES3Hes family bHLH transcription factor 3. (178 aa)
ARNT2Aryl hydrocarbon receptor nuclear translocator 2. (706 aa)
MNTMAX network transcriptional repressor. (547 aa)
USF1Upstream transcription factor 1. (373 aa)
NPAS1Neuronal PAS domain protein 1. (604 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (823 aa)
USF3Upstream transcription factor family member 3. (2234 aa)
TFE3Transcription factor binding to IGHM enhancer 3. (565 aa)
ENSUAMP00000035193Uncharacterized protein. (279 aa)
NCOA2Nuclear receptor coactivator 2. (945 aa)
NPAS4Neuronal PAS domain protein 4. (800 aa)
ENSUAMP00000036303Orange domain-containing protein. (330 aa)
SCXScleraxis bHLH transcription factor. (201 aa)
MXD3MAX dimerization protein 3. (206 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa)
OLIG2Oligodendrocyte transcription factor 2. (302 aa)
MESP2Mesoderm posterior bHLH transcription factor 2. (376 aa)
TFAP4Transcription factor AP-4. (339 aa)
ENSUAMP00000006139BHLH domain-containing protein. (282 aa)
HES7Hes family bHLH transcription factor 7. (183 aa)
HIF3AHypoxia inducible factor 3 subunit alpha. (645 aa)
NEUROG2Neurogenin 2. (272 aa)
NEUROD4Neurogenic differentiation factor. (331 aa)
NEUROD6Neurogenic differentiation factor. (337 aa)
FERD3LFer3 like bHLH transcription factor. (164 aa)
ID2Inhibitor of DNA binding 2. (134 aa)
MSGN1Mesogenin 1. (187 aa)
ENSUAMP00000001356BHLH domain-containing protein. (350 aa)
MYCLMYCL proto-oncogene, bHLH transcription factor. (364 aa)
HEYLHes related family bHLH transcription factor with YRPW motif like. (328 aa)
MXD1MAX dimerization protein 1. (220 aa)
SIM1SIM bHLH transcription factor 1. (766 aa)
SIM2SIM bHLH transcription factor 2. (650 aa)
MYOGMyogenin. (224 aa)
HAND2Heart and neural crest derivatives expressed 2. (217 aa)
SREBF2Sterol regulatory element binding transcription factor 2. (1117 aa)
ENSUAMP00000007797BHLH domain-containing protein. (70 aa)
NPAS2Neuronal PAS domain protein 2. (822 aa)
TCF23Transcription factor 23. (213 aa)
MYF6Myogenic factor 6. (242 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
MLXIPLMLX interacting protein like. (829 aa)
ENSUAMP00000021070Uncharacterized protein. (833 aa)
MSCMusculin. (198 aa)
NEUROD2Neurogenic differentiation factor. (382 aa)
USF2Upstream transcription factor 2, c-fos interacting. (335 aa)
ATOH1Atonal bHLH transcription factor 1. (356 aa)
ENSUAMP00000018971BHLH domain-containing protein. (233 aa)
TCF3Transcription factor 3. (640 aa)
NEUROG1Neurogenin 1. (251 aa)
MAXMYC associated factor X. (143 aa)
HES6Hes family bHLH transcription factor 6. (224 aa)
HELTHelt bHLH transcription factor. (242 aa)
NHLH1Nescient helix-loop-helix 1. (133 aa)
ATOH8Atonal bHLH transcription factor 8. (322 aa)
TFEBTranscription factor EB. (476 aa)
SREBF1Sterol regulatory element binding transcription factor 1. (1147 aa)
ASCL3Achaete-scute family bHLH transcription factor 3. (180 aa)
TWIST2Twist family bHLH transcription factor 2. (160 aa)
MXD4MAX dimerization protein 4. (197 aa)
MLXIPMLX interacting protein. (922 aa)
EPAS1Endothelial PAS domain protein 1. (863 aa)
ENSUAMP00000010461BHLH domain-containing protein. (178 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
FIGLAFolliculogenesis specific bHLH transcription factor. (219 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (213 aa)
MXI1BHLH domain-containing protein. (195 aa)
HES1Hes family bHLH transcription factor 1. (259 aa)
ENSUAMP00000009330BHLH domain-containing protein. (87 aa)
MLXMAX dimerization protein MLX. (288 aa)
NCOA1Nuclear receptor coactivator. (1441 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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