(31 nodes) Periplasmic binding protein-like I network (Ursus americanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GRM3	Glutamate metabotropic receptor 3. (879 aa)
	ENSUAMP00000025663	ANF_receptor domain-containing protein. (192 aa)
	GRM2	Glutamate metabotropic receptor 2. (872 aa)
	GRIN3A	Glutamate ionotropic receptor NMDA type subunit 3A. (1103 aa)
	GRIK5	Glutamate ionotropic receptor kainate type subunit 5. (969 aa)
	NPR1	Guanylate cyclase. (1115 aa)
	GRIA1	Glutamate ionotropic receptor AMPA type subunit 1. (906 aa)
	GRIN1	Glutamate ionotropic receptor NMDA type subunit 1. (814 aa)
	ENSUAMP00000029001	ANF_receptor domain-containing protein. (195 aa)
	GRM4	Glutamate metabotropic receptor 4. (947 aa)
	GRIK4	Glutamate ionotropic receptor kainate type subunit 4. (903 aa)
	GRIN2B	Glutamate ionotropic receptor NMDA type subunit 2B. (1484 aa)
	GRM6	Glutamate metabotropic receptor 6. (908 aa)
	ENSUAMP00000035186	ANF_receptor domain-containing protein. (305 aa)
	CASR	Calcium sensing receptor. (1079 aa)
	TAS1R2	Taste 1 receptor member 2. (837 aa)
	GPRC6A	G protein-coupled receptor class C group 6 member A. (928 aa)
	ENSUAMP00000015620	Uncharacterized protein. (577 aa)
	ENSUAMP00000015381	ANF_receptor domain-containing protein. (158 aa)
	GRIA3	Glutamate ionotropic receptor AMPA type subunit 3. (601 aa)
	GABBR1	Gamma-aminobutyric acid type B receptor subunit 1. (844 aa)
	GRIK3	Glutamate ionotropic receptor kainate type subunit 3. (950 aa)
	NPR2	Guanylate cyclase. (1048 aa)
	TAS1R1	Taste 1 receptor member 1. (841 aa)
	GRIN3B	Glutamate ionotropic receptor NMDA type subunit 3B; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1001 aa)
	GUCY2D	Guanylate cyclase. (1112 aa)
	GRIA4	Glutamate ionotropic receptor AMPA type subunit 4. (957 aa)
	ENSUAMP00000000349	Guanylate cyclase. (775 aa)
	NPR3	Natriuretic peptide receptor 3. (537 aa)
	TAS1R3	Taste 1 receptor member 3. (853 aa)
	GRIN2A	Glutamate ionotropic receptor NMDA type subunit 2A. (1427 aa)

Your Current Organism:

Ursus americanus

NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CASR	ENSUAMP00000035186	ENSUAMP00000035930	ENSUAMP00000035186	Calcium sensing receptor.	ANF_receptor domain-containing protein.	0.430
CASR	GABBR1	ENSUAMP00000035930	ENSUAMP00000012589	Calcium sensing receptor.	Gamma-aminobutyric acid type B receptor subunit 1.	0.583
CASR	GPRC6A	ENSUAMP00000035930	ENSUAMP00000015782	Calcium sensing receptor.	G protein-coupled receptor class C group 6 member A.	0.959
CASR	GRM2	ENSUAMP00000035930	ENSUAMP00000027035	Calcium sensing receptor.	Glutamate metabotropic receptor 2.	0.544
CASR	GRM3	ENSUAMP00000035930	ENSUAMP00000016173	Calcium sensing receptor.	Glutamate metabotropic receptor 3.	0.544
CASR	GRM6	ENSUAMP00000035930	ENSUAMP00000034522	Calcium sensing receptor.	Glutamate metabotropic receptor 6.	0.544
CASR	TAS1R1	ENSUAMP00000035930	ENSUAMP00000009589	Calcium sensing receptor.	Taste 1 receptor member 1.	0.571
CASR	TAS1R3	ENSUAMP00000035930	ENSUAMP00000016049	Calcium sensing receptor.	Taste 1 receptor member 3.	0.563
ENSUAMP00000015381	ENSUAMP00000015620	ENSUAMP00000015381	ENSUAMP00000015620	ANF_receptor domain-containing protein.	Uncharacterized protein.	0.839
ENSUAMP00000015381	GRIA1	ENSUAMP00000015381	ENSUAMP00000027706	ANF_receptor domain-containing protein.	Glutamate ionotropic receptor AMPA type subunit 1.	0.987
ENSUAMP00000015381	GRIA3	ENSUAMP00000015381	ENSUAMP00000014478	ANF_receptor domain-containing protein.	Glutamate ionotropic receptor AMPA type subunit 3.	0.990
ENSUAMP00000015381	GRIA4	ENSUAMP00000015381	ENSUAMP00000001395	ANF_receptor domain-containing protein.	Glutamate ionotropic receptor AMPA type subunit 4.	0.872
ENSUAMP00000015381	GRIK4	ENSUAMP00000015381	ENSUAMP00000033785	ANF_receptor domain-containing protein.	Glutamate ionotropic receptor kainate type subunit 4.	0.530
ENSUAMP00000015381	GRIN1	ENSUAMP00000015381	ENSUAMP00000027919	ANF_receptor domain-containing protein.	Glutamate ionotropic receptor NMDA type subunit 1.	0.450
ENSUAMP00000015381	GRIN2B	ENSUAMP00000015381	ENSUAMP00000033963	ANF_receptor domain-containing protein.	Glutamate ionotropic receptor NMDA type subunit 2B.	0.457
ENSUAMP00000015381	GRM2	ENSUAMP00000015381	ENSUAMP00000027035	ANF_receptor domain-containing protein.	Glutamate metabotropic receptor 2.	0.428
ENSUAMP00000015381	GRM3	ENSUAMP00000015381	ENSUAMP00000016173	ANF_receptor domain-containing protein.	Glutamate metabotropic receptor 3.	0.485
ENSUAMP00000015381	GRM6	ENSUAMP00000015381	ENSUAMP00000034522	ANF_receptor domain-containing protein.	Glutamate metabotropic receptor 6.	0.469
ENSUAMP00000015620	ENSUAMP00000015381	ENSUAMP00000015620	ENSUAMP00000015381	Uncharacterized protein.	ANF_receptor domain-containing protein.	0.839
ENSUAMP00000015620	GRIA1	ENSUAMP00000015620	ENSUAMP00000027706	Uncharacterized protein.	Glutamate ionotropic receptor AMPA type subunit 1.	0.988