STRINGSTRING
ENSUAMP00000021498 ENSUAMP00000021498 UGDH UGDH ABHD10 ABHD10 ENSUAMP00000001312 ENSUAMP00000001312 ENSUAMP00000001920 ENSUAMP00000001920 GSTO2 GSTO2 GSTO1 GSTO1 ENSUAMP00000002632 ENSUAMP00000002632 ENSUAMP00000003239 ENSUAMP00000003239 ENSUAMP00000003787 ENSUAMP00000003787 ENSUAMP00000003899 ENSUAMP00000003899 GSTM3 GSTM3 ENSUAMP00000004109 ENSUAMP00000004109 ENSUAMP00000004754 ENSUAMP00000004754 ENSUAMP00000004759 ENSUAMP00000004759 ENSUAMP00000004765 ENSUAMP00000004765 ENSUAMP00000004774 ENSUAMP00000004774 ENSUAMP00000005458 ENSUAMP00000005458 ENSUAMP00000006241 ENSUAMP00000006241 MAT2B MAT2B SUSD1 SUSD1 ENSUAMP00000006430 ENSUAMP00000006430 SULT1C3 SULT1C3 ENSUAMP00000008117 ENSUAMP00000008117 AHCY AHCY ENSUAMP00000009040 ENSUAMP00000009040 ENSUAMP00000009042 ENSUAMP00000009042 ENSUAMP00000009044 ENSUAMP00000009044 GSTA4 GSTA4 CHAC2 CHAC2 AKR1A1 AKR1A1 TPST1 TPST1 CNDP1 CNDP1 CNDP2 CNDP2 UGT1A1 UGT1A1 ENSUAMP00000012071 ENSUAMP00000012071 ENSUAMP00000012575 ENSUAMP00000012575 MTRR MTRR ENSUAMP00000013015 ENSUAMP00000013015 SULT2B1 SULT2B1 ENSUAMP00000013400 ENSUAMP00000013400 GGT5 GGT5 ENSUAMP00000013421 ENSUAMP00000013421 ENSUAMP00000013425 ENSUAMP00000013425 GSTT4 GSTT4 ENSUAMP00000013433 ENSUAMP00000013433 ENSUAMP00000013435 ENSUAMP00000013435 COMT COMT GSTZ1 GSTZ1 GSS GSS ENSUAMP00000015867 ENSUAMP00000015867 ENSUAMP00000015869 ENSUAMP00000015869 N6AMT1 N6AMT1 MAT1A MAT1A MGST3 MGST3 TPMT TPMT ENSUAMP00000019210 ENSUAMP00000019210 TPST2 TPST2 CHAC1 CHAC1 SLC35B2 SLC35B2 ACSM5 ACSM5 ACSM1 ACSM1 NNMT NNMT SULT1C4 SULT1C4 ESD ESD GGT7 GGT7 MTR MTR ENSUAMP00000023714 ENSUAMP00000023714 GSTK1 GSTK1 OPLAH OPLAH UGP2 UGP2 C1orf141 C1orf141 SLC35D1 SLC35D1 IMPAD1 IMPAD1 BPNT1 BPNT1 ABHD14A ABHD14A ABHD14B ABHD14B SLC26A1 SLC26A1 PODXL2 PODXL2 HPGDS HPGDS MGST2 MGST2 GGT6 GGT6 SLC35B3 SLC35B3 SLC26A2 SLC26A2 ENSUAMP00000032778 ENSUAMP00000032778 ENSUAMP00000033021 ENSUAMP00000033021 GLYAT GLYAT GCLC GCLC AS3MT AS3MT CYP1A2 CYP1A2 ENSUAMP00000035868 ENSUAMP00000035868 MAT2A MAT2A GCLM GCLM SULT4A1 SULT4A1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSUAMP00000021498Uncharacterized protein. (452 aa)
UGDHUDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (494 aa)
ABHD10Abhydrolase domain containing 10. (266 aa)
ENSUAMP00000001312Sulfotransferase; Belongs to the sulfotransferase 1 family. (312 aa)
ENSUAMP00000001920Uncharacterized protein. (229 aa)
GSTO2Glutathione S-transferase omega 2; Belongs to the GST superfamily. (244 aa)
GSTO1Glutathione S-transferase omega 1; Belongs to the GST superfamily. (278 aa)
ENSUAMP00000002632Sulfotransferase; Belongs to the sulfotransferase 1 family. (160 aa)
ENSUAMP00000003239Sulfotransferase; Belongs to the sulfotransferase 1 family. (199 aa)
ENSUAMP00000003787Uncharacterized protein. (209 aa)
ENSUAMP00000003899Uncharacterized protein; Belongs to the arylamine N-acetyltransferase family. (290 aa)
GSTM3Glutathione S-transferase. (226 aa)
ENSUAMP00000004109Uncharacterized protein; Belongs to the GST superfamily. (256 aa)
ENSUAMP00000004754UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (521 aa)
ENSUAMP00000004759Uncharacterized protein. (68 aa)
ENSUAMP00000004765UDPGT domain-containing protein; Belongs to the UDP-glycosyltransferase family. (610 aa)
ENSUAMP00000004774Uncharacterized protein. (122 aa)
ENSUAMP00000005458Uncharacterized protein. (51 aa)
ENSUAMP00000006241GST N-terminal domain-containing protein. (60 aa)
MAT2BMethionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. (324 aa)
SUSD1Sushi domain containing 1. (780 aa)
ENSUAMP00000006430Uncharacterized protein; Belongs to the GST superfamily. (226 aa)
SULT1C3Sulfotransferase; Belongs to the sulfotransferase 1 family. (304 aa)
ENSUAMP00000008117Uncharacterized protein. (230 aa)
AHCYAdenosylhomocysteinase; Belongs to the adenosylhomocysteinase family. (445 aa)
ENSUAMP00000009040GST N-terminal domain-containing protein. (150 aa)
ENSUAMP00000009042Uncharacterized protein. (158 aa)
ENSUAMP00000009044Uncharacterized protein; Belongs to the GST superfamily. (222 aa)
GSTA4Glutathione S-transferase alpha 4; Belongs to the GST superfamily. (223 aa)
CHAC2Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (184 aa)
AKR1A1Aldo-keto reductase family 1 member A1. (333 aa)
TPST1Protein-tyrosine sulfotransferase; Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate; Belongs to the protein sulfotransferase family. (356 aa)
CNDP1Carnosine dipeptidase 1. (485 aa)
CNDP2Carnosine dipeptidase 2. (473 aa)
UGT1A1UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (533 aa)
ENSUAMP00000012071GST N-terminal domain-containing protein. (193 aa)
ENSUAMP00000012575Sulfotransferase; Belongs to the sulfotransferase 1 family. (295 aa)
MTRR5-methyltetrahydrofolate-homocysteine methyltransferase reductase. (723 aa)
ENSUAMP00000013015DSBA domain-containing protein. (172 aa)
SULT2B1Sulfotransferase; Belongs to the sulfotransferase 1 family. (333 aa)
ENSUAMP00000013400Uncharacterized protein. (569 aa)
GGT5Gamma-glutamyltransferase 5. (570 aa)
ENSUAMP00000013421Uncharacterized protein. (240 aa)
ENSUAMP00000013425Uncharacterized protein; Belongs to the GST superfamily. (240 aa)
GSTT4Glutathione S-transferase theta 4; Belongs to the GST superfamily. (241 aa)
ENSUAMP00000013433Uncharacterized protein; Belongs to the GST superfamily. (242 aa)
ENSUAMP00000013435Uncharacterized protein; Belongs to the GST superfamily. (244 aa)
COMTCatechol-O-methyltransferase. (334 aa)
GSTZ1Glutathione S-transferase zeta 1; Belongs to the GST superfamily. (213 aa)
GSSGlutathione synthetase. (536 aa)
ENSUAMP00000015867Sulfotransferase; Belongs to the sulfotransferase 1 family. (307 aa)
ENSUAMP00000015869Sulfotransferase; Belongs to the sulfotransferase 1 family. (310 aa)
N6AMT1N-6 adenine-specific DNA methyltransferase 1. (214 aa)
MAT1AS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (396 aa)
MGST3Microsomal glutathione S-transferase 3. (152 aa)
TPMTThiopurine S-methyltransferase. (220 aa)
ENSUAMP00000019210Uncharacterized protein. (148 aa)
TPST2Protein-tyrosine sulfotransferase; Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate; Belongs to the protein sulfotransferase family. (421 aa)
CHAC1Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (234 aa)
SLC35B2Solute carrier family 35 member B2. (432 aa)
ACSM5Acyl-CoA synthetase medium chain family member 5. (588 aa)
ACSM1Acyl-CoA synthetase medium chain family member 1. (577 aa)
NNMTNicotinamide N-methyltransferase. (264 aa)
SULT1C4Sulfotransferase; Belongs to the sulfotransferase 1 family. (303 aa)
ESDS-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (292 aa)
GGT7Gamma-glutamyltransferase 7. (662 aa)
MTRMethionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1178 aa)
ENSUAMP00000023714Uncharacterized protein. (125 aa)
GSTK1Glutathione S-transferase kappa. (190 aa)
OPLAH5-oxoprolinase, ATP-hydrolysing. (1289 aa)
UGP2UTP--glucose-1-phosphate uridylyltransferase. (508 aa)
C1orf141Chromosome 1 open reading frame 141. (392 aa)
SLC35D1Solute carrier family 35 member D1. (355 aa)
IMPAD1Inositol monophosphatase domain containing 1. (360 aa)
BPNT13'(2'), 5'-bisphosphate nucleotidase 1. (323 aa)
ABHD14AAbhydrolase domain containing 14A. (276 aa)
ABHD14BAbhydrolase domain containing 14B. (291 aa)
SLC26A1Sulfate anion transporter 1; Mediates sulfate transport with high affinity. Mediates oxalate transport. Mediates bicarbonate transport. Does not accept succinate as cosubstrate; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (704 aa)
PODXL2Podocalyxin like 2. (608 aa)
HPGDSHematopoietic prostaglandin D synthase; Belongs to the GST superfamily. (199 aa)
MGST2Microsomal glutathione S-transferase 2. (146 aa)
GGT6Gamma-glutamyltransferase 6. (497 aa)
SLC35B3Solute carrier family 35 member B3. (423 aa)
SLC26A2Sulfate transporter; Sulfate transporter. May play a role in endochondral bone formation; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (741 aa)
ENSUAMP00000032778Sulfotransferase; Belongs to the sulfotransferase 1 family. (171 aa)
ENSUAMP00000033021Uncharacterized protein. (295 aa)
GLYATUncharacterized protein. (295 aa)
GCLCGlutamate-cysteine ligase catalytic subunit. (576 aa)
AS3MTArsenite methyltransferase. (457 aa)
CYP1A2Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family. (512 aa)
ENSUAMP00000035868Sulfotransferase; Belongs to the sulfotransferase 1 family. (286 aa)
MAT2AS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (395 aa)
GCLMGlutamate-cysteine ligase modifier subunit. (278 aa)
SULT4A1Sulfotransferase; Belongs to the sulfotransferase 1 family. (284 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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