36 items (Ursus americanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CYP46A1	Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family. (506 aa)
	OSBP2	Oxysterol-binding protein; Belongs to the OSBP family. (744 aa)
	AMACR	Alpha-methylacyl-CoA racemase. (248 aa)
	OSBPL7	Oxysterol binding protein like 7. (941 aa)
	SCP2D1	SCP2 sterol binding domain containing 1. (156 aa)
	ENSUAMP00000004665	AMP-binding domain-containing protein. (629 aa)
	ENSUAMP00000004668	Uncharacterized protein. (95 aa)
	HSDL2	Hydroxysteroid dehydrogenase like 2. (390 aa)
	CYP7B1	Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. (485 aa)
	AKR1C8P	Aldo-keto reductase family 1 member C8, pseudogene. (324 aa)
	NCOA1	Nuclear receptor coactivator. (1441 aa)
	OSBP	Oxysterol-binding protein; Belongs to the OSBP family. (793 aa)
	ACOT8	Acyl-CoA thioesterase 8. (317 aa)
	OSBPL1A	Oxysterol-binding protein; Belongs to the OSBP family. (856 aa)
	OSBPL6	Oxysterol-binding protein; Belongs to the OSBP family. (954 aa)
	ENSUAMP00000017381	Uncharacterized protein. (128 aa)
	HSD3B7	Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7; Belongs to the 3-beta-HSD family. (369 aa)
	CYP39A1	Cytochrome P450 family 39 subfamily A member 1; Belongs to the cytochrome P450 family. (469 aa)
	AKR1D1	Aldo-keto reductase family 1 member D1. (323 aa)
	SCP2	Sterol carrier protein 2. (457 aa)
	CYP8B1	Cytochrome P450 family 8 subfamily B member 1; Belongs to the cytochrome P450 family. (501 aa)
	OSBPL9	Oxysterol-binding protein; Belongs to the OSBP family. (660 aa)
	ENSUAMP00000024543	Uncharacterized protein. (554 aa)
	ENSUAMP00000024577	Uncharacterized protein. (146 aa)
	ABCB11	ATP binding cassette subfamily B member 11. (1319 aa)
	PTGIS	Prostaglandin I2 synthase; Belongs to the cytochrome P450 family. (499 aa)
	RXRA	Retinoid X receptor alpha. (469 aa)
	ENSUAMP00000027762	Uncharacterized protein. (188 aa)
	CYP27A1	Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family. (441 aa)
	ENSUAMP00000028186	Uncharacterized protein. (505 aa)
	SLC27A2	Solute carrier family 27 member 2. (385 aa)
	OSBPL3	Oxysterol-binding protein; Belongs to the OSBP family. (891 aa)
	ENSUAMP00000034832	PH domain-containing protein. (61 aa)
	NCOA2	Nuclear receptor coactivator 2. (945 aa)
	ACOX2	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (681 aa)
	NR1H4	Nuclear receptor subfamily 1 group H member 4. (482 aa)

Your Current Organism:

Ursus americanus

NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCB11	CYP8B1	ENSUAMP00000024712	ENSUAMP00000022678	ATP binding cassette subfamily B member 11.	Cytochrome P450 family 8 subfamily B member 1; Belongs to the cytochrome P450 family.	0.630
ABCB11	NR1H4	ENSUAMP00000024712	ENSUAMP00000036456	ATP binding cassette subfamily B member 11.	Nuclear receptor subfamily 1 group H member 4.	0.670
ABCB11	OSBPL6	ENSUAMP00000024712	ENSUAMP00000016092	ATP binding cassette subfamily B member 11.	Oxysterol-binding protein; Belongs to the OSBP family.	0.400
ACOT8	ACOX2	ENSUAMP00000012788	ENSUAMP00000035772	Acyl-CoA thioesterase 8.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.600
ACOT8	ENSUAMP00000004665	ENSUAMP00000012788	ENSUAMP00000004665	Acyl-CoA thioesterase 8.	AMP-binding domain-containing protein.	0.889
ACOT8	ENSUAMP00000004668	ENSUAMP00000012788	ENSUAMP00000004668	Acyl-CoA thioesterase 8.	Uncharacterized protein.	0.889
ACOT8	ENSUAMP00000024543	ENSUAMP00000012788	ENSUAMP00000024543	Acyl-CoA thioesterase 8.	Uncharacterized protein.	0.565
ACOT8	ENSUAMP00000024577	ENSUAMP00000012788	ENSUAMP00000024577	Acyl-CoA thioesterase 8.	Uncharacterized protein.	0.565
ACOT8	HSDL2	ENSUAMP00000012788	ENSUAMP00000006360	Acyl-CoA thioesterase 8.	Hydroxysteroid dehydrogenase like 2.	0.587
ACOT8	SCP2	ENSUAMP00000012788	ENSUAMP00000020492	Acyl-CoA thioesterase 8.	Sterol carrier protein 2.	0.967
ACOT8	SCP2D1	ENSUAMP00000012788	ENSUAMP00000003895	Acyl-CoA thioesterase 8.	SCP2 sterol binding domain containing 1.	0.497
ACOX2	ACOT8	ENSUAMP00000035772	ENSUAMP00000012788	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	Acyl-CoA thioesterase 8.	0.600
ACOX2	AKR1D1	ENSUAMP00000035772	ENSUAMP00000019949	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	Aldo-keto reductase family 1 member D1.	0.456
ACOX2	AMACR	ENSUAMP00000035772	ENSUAMP00000002709	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	Alpha-methylacyl-CoA racemase.	0.966
ACOX2	CYP46A1	ENSUAMP00000035772	ENSUAMP00000013176	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family.	0.428
ACOX2	CYP8B1	ENSUAMP00000035772	ENSUAMP00000022678	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	Cytochrome P450 family 8 subfamily B member 1; Belongs to the cytochrome P450 family.	0.607
ACOX2	ENSUAMP00000004665	ENSUAMP00000035772	ENSUAMP00000004665	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	AMP-binding domain-containing protein.	0.548
ACOX2	ENSUAMP00000004668	ENSUAMP00000035772	ENSUAMP00000004668	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	Uncharacterized protein.	0.548
ACOX2	ENSUAMP00000017381	ENSUAMP00000035772	ENSUAMP00000017381	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	Uncharacterized protein.	0.512
ACOX2	ENSUAMP00000024543	ENSUAMP00000035772	ENSUAMP00000024543	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	Uncharacterized protein.	0.948