STRINGSTRING
PTGIS PTGIS NR1H4 NR1H4 NCOA2 NCOA2 ENSUAMP00000028186 ENSUAMP00000028186 CYP27A1 CYP27A1 ENSUAMP00000027762 ENSUAMP00000027762 RXRA RXRA CYP8B1 CYP8B1 AKR1D1 AKR1D1 HSD3B7 HSD3B7 NCOA1 NCOA1 AKR1C8P AKR1C8P CYP7B1 CYP7B1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PTGISProstaglandin I2 synthase; Belongs to the cytochrome P450 family. (499 aa)
NR1H4Nuclear receptor subfamily 1 group H member 4. (482 aa)
NCOA2Nuclear receptor coactivator 2. (945 aa)
ENSUAMP00000028186Uncharacterized protein. (505 aa)
CYP27A1Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family. (441 aa)
ENSUAMP00000027762Uncharacterized protein. (188 aa)
RXRARetinoid X receptor alpha. (469 aa)
CYP8B1Cytochrome P450 family 8 subfamily B member 1; Belongs to the cytochrome P450 family. (501 aa)
AKR1D1Aldo-keto reductase family 1 member D1. (323 aa)
HSD3B7Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7; Belongs to the 3-beta-HSD family. (369 aa)
NCOA1Nuclear receptor coactivator. (1441 aa)
AKR1C8PAldo-keto reductase family 1 member C8, pseudogene. (324 aa)
CYP7B1Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. (485 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.