STRINGSTRING
TLE4 TLE4 BCL9L BCL9L ENSUAMP00000036463 ENSUAMP00000036463 TCF7L1 TCF7L1 ENSUAMP00000035777 ENSUAMP00000035777 ENSUAMP00000033950 ENSUAMP00000033950 ENSUAMP00000033949 ENSUAMP00000033949 ENSUAMP00000033945 ENSUAMP00000033945 ENSUAMP00000033939 ENSUAMP00000033939 ENSUAMP00000033919 ENSUAMP00000033919 ENSUAMP00000033918 ENSUAMP00000033918 ENSUAMP00000033915 ENSUAMP00000033915 H2BC11 H2BC11 EP300 EP300 ENSUAMP00000031302 ENSUAMP00000031302 TLE3 TLE3 CREBBP CREBBP ENSUAMP00000029966 ENSUAMP00000029966 H2BE1 H2BE1 ENSUAMP00000029196 ENSUAMP00000029196 ENSUAMP00000029195 ENSUAMP00000029195 ENSUAMP00000029193 ENSUAMP00000029193 H2BC21 H2BC21 KAT5 KAT5 TRRAP TRRAP TCF7L2 TCF7L2 H3-3A H3-3A ENSUAMP00000022270 ENSUAMP00000022270 BCL9 BCL9 ENSUAMP00000020853 ENSUAMP00000020853 ENSUAMP00000020825 ENSUAMP00000020825 ENSUAMP00000020808 ENSUAMP00000020808 LEO1 LEO1 H2AX H2AX PYGO1 PYGO1 PYGO2 PYGO2 HDAC1 HDAC1 TERT TERT CTNNB1 CTNNB1 HIST3H2BB HIST3H2BB ENSUAMP00000017069 ENSUAMP00000017069 ENSUAMP00000016536 ENSUAMP00000016536 MEN1 MEN1 ENSUAMP00000014288 ENSUAMP00000014288 ENSUAMP00000014264 ENSUAMP00000014264 ENSUAMP00000014262 ENSUAMP00000014262 ENSUAMP00000014260 ENSUAMP00000014260 ENSUAMP00000014243 ENSUAMP00000014243 ENSUAMP00000014224 ENSUAMP00000014224 ENSUAMP00000014212 ENSUAMP00000014212 ENSUAMP00000014210 ENSUAMP00000014210 ENSUAMP00000014208 ENSUAMP00000014208 ENSUAMP00000012266 ENSUAMP00000012266 CDC73 CDC73 ENSUAMP00000007849 ENSUAMP00000007849 TCF7 TCF7 ENSUAMP00000007225 ENSUAMP00000007225 ENSUAMP00000006561 ENSUAMP00000006561 RUVBL1 RUVBL1 ENSUAMP00000006335 ENSUAMP00000006335 ENSUAMP00000006323 ENSUAMP00000006323 ENSUAMP00000006306 ENSUAMP00000006306 ENSUAMP00000006129 ENSUAMP00000006129 SLC39A13 SLC39A13 RBBP5 RBBP5 H2BC1 H2BC1 ASH2L ASH2L ENSUAMP00000004341 ENSUAMP00000004341 H2AZ1 H2AZ1 H3F3B H3F3B ENSUAMP00000003497 ENSUAMP00000003497 ENSUAMP00000002618 ENSUAMP00000002618 ENSUAMP00000000906 ENSUAMP00000000906
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TLE4TLE family member 4, transcriptional corepressor. (702 aa)
BCL9LBCL9 like. (1497 aa)
ENSUAMP00000036463TLE_N domain-containing protein. (120 aa)
TCF7L1Transcription factor 7 like 1. (597 aa)
ENSUAMP00000035777HMG box domain-containing protein. (191 aa)
ENSUAMP00000033950annotation not available (103 aa)
ENSUAMP00000033949annotation not available (126 aa)
ENSUAMP00000033945Histone H3; Belongs to the histone H3 family. (93 aa)
ENSUAMP00000033939Histone H2B; Belongs to the histone H2B family. (132 aa)
ENSUAMP00000033919Histone domain-containing protein; Belongs to the histone H2B family. (128 aa)
ENSUAMP00000033918annotation not available (103 aa)
ENSUAMP00000033915Histone domain-containing protein. (125 aa)
H2BC11Histone H2B; Belongs to the histone H2B family. (126 aa)
EP300E1A binding protein p300. (2399 aa)
ENSUAMP00000031302Histone domain-containing protein; Belongs to the histone H2B family. (170 aa)
TLE3TLE family member 3, transcriptional corepressor. (787 aa)
CREBBPCREB binding protein. (2333 aa)
ENSUAMP00000029966annotation not available (113 aa)
H2BE1Histone H2B; Belongs to the histone H2B family. (122 aa)
ENSUAMP00000029196Histone H3; Belongs to the histone H3 family. (136 aa)
ENSUAMP00000029195annotation not available (103 aa)
ENSUAMP00000029193annotation not available (126 aa)
H2BC21Histone H2B; Belongs to the histone H2B family. (126 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa)
TRRAPTransformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3832 aa)
TCF7L2Transcription factor 7 like 2. (524 aa)
H3-3AHistone domain-containing protein. (142 aa)
ENSUAMP00000022270Histone H2B; Belongs to the histone H2B family. (127 aa)
BCL9BCL9 transcription coactivator. (1426 aa)
ENSUAMP00000020853Histone domain-containing protein. (178 aa)
ENSUAMP00000020825annotation not available (103 aa)
ENSUAMP00000020808annotation not available (126 aa)
LEO1LEO1 homolog, Paf1/RNA polymerase II complex component. (618 aa)
H2AXHistone H2A; Belongs to the histone H2A family. (143 aa)
PYGO1Pygopus family PHD finger 1. (398 aa)
PYGO2Pygopus family PHD finger 2. (369 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (479 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1117 aa)
CTNNB1Catenin beta 1. (781 aa)
HIST3H2BBHistone H2B; Belongs to the histone H2B family. (126 aa)
ENSUAMP00000017069Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSUAMP00000016536Uncharacterized protein. (119 aa)
MEN1Menin 1. (610 aa)
ENSUAMP00000014288Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSUAMP00000014264annotation not available (136 aa)
ENSUAMP00000014262Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (100 aa)
ENSUAMP00000014260annotation not available (103 aa)
ENSUAMP00000014243Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSUAMP00000014224annotation not available (103 aa)
ENSUAMP00000014212annotation not available (126 aa)
ENSUAMP00000014210Uncharacterized protein. (379 aa)
ENSUAMP00000014208WD_REPEATS_REGION domain-containing protein. (574 aa)
ENSUAMP00000012266CTNNB1_binding domain-containing protein. (162 aa)
CDC73Cell division cycle 73. (519 aa)
ENSUAMP00000007849TLE_N domain-containing protein. (144 aa)
TCF7Transcription factor 7. (443 aa)
ENSUAMP00000007225Histone domain-containing protein; Belongs to the histone H2B family. (122 aa)
ENSUAMP00000006561Histone H2B; Belongs to the histone H2B family. (126 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
ENSUAMP00000006335Histone H2B; Belongs to the histone H2B family. (135 aa)
ENSUAMP00000006323Histone H3; Belongs to the histone H3 family. (136 aa)
ENSUAMP00000006306annotation not available (103 aa)
ENSUAMP00000006129Histone domain-containing protein. (199 aa)
SLC39A13Solute carrier family 39 member 13. (454 aa)
RBBP5RB binding protein 5, histone lysine methyltransferase complex subunit. (475 aa)
H2BC1Histone H2B; Belongs to the histone H2B family. (127 aa)
ASH2LASH2 like, histone lysine methyltransferase complex subunit. (628 aa)
ENSUAMP00000004341annotation not available (103 aa)
H2AZ1Histone H2A; Belongs to the histone H2A family. (159 aa)
H3F3BHistone H3; Belongs to the histone H3 family. (136 aa)
ENSUAMP00000003497Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
ENSUAMP00000002618Histone H2A; Belongs to the histone H2A family. (113 aa)
ENSUAMP00000000906TLE_N domain-containing protein. (130 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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