STRINGSTRING
PTPRJ PTPRJ ENSUAMP00000005484 ENSUAMP00000005484 ENSUAMP00000005376 ENSUAMP00000005376 UBE2V1 UBE2V1 PRKCQ PRKCQ ENSUAMP00000004531 ENSUAMP00000004531 CD3E CD3E CD3D CD3D CD3G CD3G PSMB1 PSMB1 ENSUAMP00000003404 ENSUAMP00000003404 ENSUAMP00000003372 ENSUAMP00000003372 ENSUAMP00000003232 ENSUAMP00000003232 ENSUAMP00000003158 ENSUAMP00000003158 ENSUAMP00000003155 ENSUAMP00000003155 TAB2 TAB2 PSMD11 PSMD11 ENSUAMP00000002310 ENSUAMP00000002310 PSMD2 PSMD2 PSMD1 PSMD1 PSMC4 PSMC4 ENSUAMP00000001854 ENSUAMP00000001854 ENSUAMP00000001604 ENSUAMP00000001604 PSMB2 PSMB2 ENSUAMP00000000292 ENSUAMP00000000292 PSMD8 PSMD8 ITK ITK PSMA2 PSMA2 PSMB7 PSMB7 ENSUAMP00000033331 ENSUAMP00000033331 PSMA7 PSMA7 ENSUAMP00000032923 ENSUAMP00000032923 ENSUAMP00000032511 ENSUAMP00000032511 FBXW11 FBXW11 MAP3K7 MAP3K7 CARD11 CARD11 ENSUAMP00000031438 ENSUAMP00000031438 PSME2 PSME2 PSMB9 PSMB9 ENSUAMP00000037283 ENSUAMP00000037283 ENSUAMP00000037175 ENSUAMP00000037175 LCP2 LCP2 PSMD12 PSMD12 CHUK CHUK ENSUAMP00000036637 ENSUAMP00000036637 PAG1 PAG1 INPP5D INPP5D PSMD4 PSMD4 ENSUAMP00000035755 ENSUAMP00000035755 CD4 CD4 ENSUAMP00000035331 ENSUAMP00000035331 CSK CSK NCK1 NCK1 PSMB8 PSMB8 PSMD13 PSMD13 PSME3 PSME3 ENSUAMP00000016547 ENSUAMP00000016547 PDPK1 PDPK1 TRBV30 TRBV30 ENSUAMP00000016042 ENSUAMP00000016042 TRBV28 TRBV28 ENSUAMP00000015824 ENSUAMP00000015824 ENSUAMP00000015819 ENSUAMP00000015819 ENSUAMP00000015817 ENSUAMP00000015817 ENSUAMP00000015662 ENSUAMP00000015662 TRBV19 TRBV19 TRBV16 TRBV16 ENSUAMP00000014720 ENSUAMP00000014720 ENSUAMP00000014590 ENSUAMP00000014590 TRBV13 TRBV13 ENSUAMP00000014588 ENSUAMP00000014588 IKBKG IKBKG ENSUAMP00000012220 ENSUAMP00000012220 ENSUAMP00000011260 ENSUAMP00000011260 ENSUAMP00000011223 ENSUAMP00000011223 PAK3 PAK3 PSMD9 PSMD9 PIK3R1 PIK3R1 PSMB5 PSMB5 ENSUAMP00000010232 ENSUAMP00000010232 PLCG1 PLCG1 SPNS3 SPNS3 PSME4 PSME4 PSMD7 PSMD7 PSMA3 PSMA3 PIK3CA PIK3CA PSMC5 PSMC5 GRAP2 GRAP2 PLCG2 PLCG2 SKP1 SKP1 PSMF1 PSMF1 PSMB11 PSMB11 ENSUAMP00000007195 ENSUAMP00000007195 CD101 CD101 PAK1 PAK1 ENSUAMP00000006872 ENSUAMP00000006872 ENSUAMP00000006865 ENSUAMP00000006865 ENSUAMP00000006595 ENSUAMP00000006595 PSMB3 PSMB3 PSMB6 PSMB6 ENSUAMP00000006110 ENSUAMP00000006110 PSME1 PSME1 FYB1 FYB1 PSMA6 PSMA6 NFKBIA NFKBIA TRAF6 TRAF6 RELA RELA PSMB10 PSMB10 ENSUAMP00000026056 ENSUAMP00000026056 PSMA1 PSMA1 ENSUAMP00000025192 ENSUAMP00000025192 PSMC2 PSMC2 PSMB4 PSMB4 BCL10 BCL10 PAK2 PAK2 ENSUAMP00000023926 ENSUAMP00000023926 ENSUAMP00000023925 ENSUAMP00000023925 ENSUAMP00000023892 ENSUAMP00000023892 ENSUAMP00000023891 ENSUAMP00000023891 RIPK2 RIPK2 ENSUAMP00000022960 ENSUAMP00000022960 PSMA4 PSMA4 ENSUAMP00000022131 ENSUAMP00000022131 ENSUAMP00000022022 ENSUAMP00000022022 ENSUAMP00000021443 ENSUAMP00000021443 NFKB1 NFKB1 PSMD5 PSMD5 ENSUAMP00000020823 ENSUAMP00000020823 ENSUAMP00000020715 ENSUAMP00000020715 KXD1 KXD1 IKBKB IKBKB ENSUAMP00000020458 ENSUAMP00000020458 PSMD10 PSMD10 SPNS1 SPNS1 ENSUAMP00000019945 ENSUAMP00000019945 PSMD3 PSMD3 ENSUAMP00000019252 ENSUAMP00000019252 HLA-DRA HLA-DRA ENSUAMP00000018130 ENSUAMP00000018130 ENSUAMP00000017692 ENSUAMP00000017692 PSMC6 PSMC6 ENSUAMP00000029280 ENSUAMP00000029280 CUL1 CUL1 WAS WAS ENSUAMP00000027679 ENSUAMP00000027679 TMEM189-UBE2V1 TMEM189-UBE2V1 PSMC3 PSMC3 ENSUAMP00000005886 ENSUAMP00000005886 ENSUAMP00000005735 ENSUAMP00000005735 ENSUAMP00000005692 ENSUAMP00000005692
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PTPRJProtein tyrosine phosphatase receptor type J. (1211 aa)
ENSUAMP00000005484Ig-like domain-containing protein. (156 aa)
ENSUAMP00000005376Ig-like domain-containing protein. (115 aa)
UBE2V1Ubiquitin conjugating enzyme E2 V1. (156 aa)
PRKCQProtein kinase C theta. (526 aa)
ENSUAMP00000004531AAA domain-containing protein; Belongs to the AAA ATPase family. (421 aa)
CD3ECD3e molecule. (207 aa)
CD3DCD3d molecule. (171 aa)
CD3GCD3g molecule. (164 aa)
PSMB1Proteasome subunit beta. (241 aa)
ENSUAMP00000003404annotation not available (156 aa)
ENSUAMP00000003372Uncharacterized protein. (157 aa)
ENSUAMP00000003232annotation not available (156 aa)
ENSUAMP00000003158annotation not available (136 aa)
ENSUAMP00000003155annotation not available (168 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (683 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (418 aa)
ENSUAMP00000002310Ig-like domain-containing protein. (156 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (683 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (400 aa)
ENSUAMP00000001854Ig-like domain-containing protein. (168 aa)
ENSUAMP00000001604Ig-like domain-containing protein. (136 aa)
PSMB2Proteasome subunit beta. (167 aa)
ENSUAMP00000000292PCI domain-containing protein. (389 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (351 aa)
ITKTyrosine-protein kinase. (628 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
PSMB7Proteasome subunit beta. (277 aa)
ENSUAMP00000033331UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (172 aa)
PSMA7Proteasome endopeptidase complex. (248 aa)
ENSUAMP00000032923Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (387 aa)
ENSUAMP00000032511Protein kinase domain-containing protein. (132 aa)
FBXW11F-box and WD repeat domain containing 11. (543 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
CARD11Caspase recruitment domain family member 11. (1123 aa)
ENSUAMP00000031438Protein kinase domain-containing protein. (456 aa)
PSME2Proteasome activator subunit 2. (239 aa)
PSMB9Proteasome subunit beta. (220 aa)
ENSUAMP00000037283Ig-like domain-containing protein. (145 aa)
ENSUAMP00000037175MPN domain-containing protein. (156 aa)
LCP2Lymphocyte cytosolic protein 2. (511 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
ENSUAMP00000036637PCI domain-containing protein. (405 aa)
PAG1Phosphoprotein membrane anchor with glycosphingolipid microdomains 1. (434 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1197 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (344 aa)
ENSUAMP00000035755Protein kinase domain-containing protein. (105 aa)
CD4CD4 molecule. (469 aa)
ENSUAMP00000035331Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (506 aa)
CSKTyrosine-protein kinase. (450 aa)
NCK1Cytoplasmic protein. (377 aa)
PSMB8Proteasome subunit beta. (276 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (376 aa)
PSME3Proteasome activator subunit 3. (254 aa)
ENSUAMP00000016547MHC_II_beta domain-containing protein. (275 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (531 aa)
TRBV30T cell receptor beta variable 30 (gene/pseudogene). (117 aa)
ENSUAMP00000016042Ig-like domain-containing protein. (387 aa)
TRBV28T cell receptor beta variable 28. (113 aa)
ENSUAMP00000015824Ig-like domain-containing protein. (166 aa)
ENSUAMP00000015819Ig-like domain-containing protein. (141 aa)
ENSUAMP00000015817Ig-like domain-containing protein. (126 aa)
ENSUAMP00000015662UBIQUITIN_CONJUGAT_2 domain-containing protein. (147 aa)
TRBV19T cell receptor beta variable 19. (153 aa)
TRBV16T cell receptor beta variable 16 (gene/pseudogene). (127 aa)
ENSUAMP00000014720Ig-like domain-containing protein. (177 aa)
ENSUAMP00000014590Ig-like domain-containing protein. (148 aa)
TRBV13T cell receptor beta variable 13. (123 aa)
ENSUAMP00000014588IGv domain-containing protein. (107 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (442 aa)
ENSUAMP00000012220ATPase_AAA_core domain-containing protein. (174 aa)
ENSUAMP00000011260DUF1968 domain-containing protein. (153 aa)
ENSUAMP00000011223Uncharacterized protein. (224 aa)
PAK3P21 (RAC1) activated kinase 3. (547 aa)
PSMD9PDZ domain-containing protein. (309 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (676 aa)
PSMB5Proteasome subunit beta. (263 aa)
ENSUAMP00000010232Ubiquitin-like domain-containing protein. (88 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1256 aa)
SPNS3Sphingolipid transporter 3 (putative). (428 aa)
PSME4Proteasome activator subunit 4. (1436 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (322 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
GRAP2GRB2 related adaptor protein 2. (316 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1252 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (150 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
PSMB11Proteasome subunit beta. (292 aa)
ENSUAMP00000007195Ig-like domain-containing protein. (196 aa)
CD101CD101 molecule. (968 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
ENSUAMP00000006872MHC_II_beta domain-containing protein. (218 aa)
ENSUAMP00000006865MHC_II_beta domain-containing protein. (274 aa)
ENSUAMP00000006595Ig-like domain-containing protein; Belongs to the MHC class II family. (202 aa)
PSMB3Proteasome subunit beta. (202 aa)
PSMB6Proteasome subunit beta. (219 aa)
ENSUAMP00000006110Ig-like domain-containing protein. (196 aa)
PSME1Proteasome activator subunit 1. (249 aa)
FYB1FYN binding protein 1. (765 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
NFKBIANFKB inhibitor alpha. (314 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
RELARELA proto-oncogene, NF-kB subunit. (508 aa)
PSMB10Proteasome subunit beta 10. (327 aa)
ENSUAMP00000026056MitMem_reg domain-containing protein. (95 aa)
PSMA1Proteasome subunit alpha type. (269 aa)
ENSUAMP00000025192Ubiquitin-like domain-containing protein. (156 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
BCL10BCL10 immune signaling adaptor. (234 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
ENSUAMP00000023926Ig-like domain-containing protein. (151 aa)
ENSUAMP00000023925Ig-like domain-containing protein. (180 aa)
ENSUAMP00000023892Tyrosine-protein phosphatase domain-containing protein. (118 aa)
ENSUAMP00000023891Tyrosine-protein phosphatase domain-containing protein. (135 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (536 aa)
ENSUAMP00000022960Uncharacterized protein. (70 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
ENSUAMP00000022131Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (636 aa)
ENSUAMP00000022022Uncharacterized protein. (107 aa)
ENSUAMP00000021443Ubiquitin-like domain-containing protein. (77 aa)
NFKB1Nuclear factor kappa B subunit 1. (972 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (504 aa)
ENSUAMP00000020823IGv domain-containing protein. (156 aa)
ENSUAMP00000020715Ubiquitin-like domain-containing protein. (132 aa)
KXD1KxDL motif containing 1. (128 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (703 aa)
ENSUAMP00000020458IGv domain-containing protein. (196 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (151 aa)
SPNS1Sphingolipid transporter 1 (putative). (528 aa)
ENSUAMP00000019945Uncharacterized protein. (237 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (536 aa)
ENSUAMP00000019252Ig-like domain-containing protein. (196 aa)
HLA-DRAMajor histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (254 aa)
ENSUAMP00000018130Ig-like domain-containing protein. (155 aa)
ENSUAMP00000017692Uncharacterized protein. (704 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa)
ENSUAMP00000029280DUF1968 domain-containing protein. (198 aa)
CUL1Cullin 1; Belongs to the cullin family. (742 aa)
WASWASP actin nucleation promoting factor. (503 aa)
ENSUAMP00000027679Uncharacterized protein. (51 aa)
TMEM189-UBE2V1TMEM189-UBE2V1 readthrough. (247 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (439 aa)
ENSUAMP00000005886Ig-like domain-containing protein. (157 aa)
ENSUAMP00000005735PROTEASOME_ALPHA_1 domain-containing protein. (80 aa)
ENSUAMP00000005692annotation not available (156 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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