STRINGSTRING
FMO2 FMO2 ENSUAMP00000017348 ENSUAMP00000017348 CYP2F1 CYP2F1 ENSUAMP00000017402 ENSUAMP00000017402 ENSUAMP00000018378 ENSUAMP00000018378 ENSUAMP00000018414 ENSUAMP00000018414 CYP39A1 CYP39A1 ENSUAMP00000019082 ENSUAMP00000019082 CYP1B1 CYP1B1 ENSUAMP00000019124 ENSUAMP00000019124 CYP2R1 CYP2R1 ENSUAMP00000019443 ENSUAMP00000019443 ENSUAMP00000019446 ENSUAMP00000019446 BPHL BPHL ENSUAMP00000020529 ENSUAMP00000020529 CYP24A1 CYP24A1 ENSUAMP00000021070 ENSUAMP00000021070 HSP90AB1 HSP90AB1 FDX1 FDX1 ENSUAMP00000021540 ENSUAMP00000021540 ENSUAMP00000022233 ENSUAMP00000022233 ENSUAMP00000022235 ENSUAMP00000022235 CYP8B1 CYP8B1 ENSUAMP00000022865 ENSUAMP00000022865 CBR3 CBR3 ENSUAMP00000023021 ENSUAMP00000023021 ENSUAMP00000023027 ENSUAMP00000023027 ENSUAMP00000023045 ENSUAMP00000023045 PTGS1 PTGS1 CYP20A1 CYP20A1 AADACL4 AADACL4 AADACL3 AADACL3 ENSUAMP00000026182 ENSUAMP00000026182 ENSUAMP00000026294 ENSUAMP00000026294 PTGIS PTGIS RXRA RXRA ENSUAMP00000027042 ENSUAMP00000027042 ENSUAMP00000027762 ENSUAMP00000027762 CYP27A1 CYP27A1 ENSUAMP00000028019 ENSUAMP00000028019 PTGES3 PTGES3 ENSUAMP00000028186 ENSUAMP00000028186 FMO5 FMO5 ENSUAMP00000028801 ENSUAMP00000028801 ENSUAMP00000028802 ENSUAMP00000028802 CYP21A2 CYP21A2 FMO1 FMO1 FMO4 FMO4 CMBL CMBL CCDC160 CCDC160 CYP11A1 CYP11A1 ENSUAMP00000032152 ENSUAMP00000032152 ARNT2 ARNT2 AOC1 AOC1 ENSUAMP00000033175 ENSUAMP00000033175 CYP51A1 CYP51A1 CBFA2T3 CBFA2T3 ENSUAMP00000033863 ENSUAMP00000033863 CYP2E1 CYP2E1 MARC2 MARC2 ENSUAMP00000033988 ENSUAMP00000033988 CYP26B1 CYP26B1 CYP4B1 CYP4B1 CYP4X1 CYP4X1 ENSUAMP00000034394 ENSUAMP00000034394 CYB5R3 CYB5R3 ENSUAMP00000000355 ENSUAMP00000000355 ENSUAMP00000000729 ENSUAMP00000000729 ENSUAMP00000001000 ENSUAMP00000001000 ENSUAMP00000001018 ENSUAMP00000001018 ENSUAMP00000001136 ENSUAMP00000001136 ENSUAMP00000001533 ENSUAMP00000001533 ENSUAMP00000001835 ENSUAMP00000001835 CYP19A1 CYP19A1 ENSUAMP00000002638 ENSUAMP00000002638 CYP26A1 CYP26A1 CYP26C1 CYP26C1 ENSUAMP00000003052 ENSUAMP00000003052 ADH6 ADH6 ENSUAMP00000003802 ENSUAMP00000003802 RUNX1T1 RUNX1T1 ENSUAMP00000005042 ENSUAMP00000005042 ALDH1B1 ALDH1B1 ENSUAMP00000006303 ENSUAMP00000006303 AIP AIP ENSUAMP00000006803 ENSUAMP00000006803 CYP7B1 CYP7B1 ENSUAMP00000007578 ENSUAMP00000007578 CES2 CES2 CES3 CES3 NCOA1 NCOA1 ENSUAMP00000009417 ENSUAMP00000009417 ALDH16A1 ALDH16A1 FAM78A FAM78A NQO2 NQO2 ENSUAMP00000010632 ENSUAMP00000010632 ENSUAMP00000010766 ENSUAMP00000010766 ENSUAMP00000011012 ENSUAMP00000011012 CYP27C1 CYP27C1 POMC POMC ENSUAMP00000012176 ENSUAMP00000012176 ENSUAMP00000012528 ENSUAMP00000012528 CYP2B6 CYP2B6 ARNT ARNT FDXR FDXR FADS6 FADS6 ENSUAMP00000013046 ENSUAMP00000013046 CYP46A1 CYP46A1 ENSUAMP00000013261 ENSUAMP00000013261 CYP2J2 CYP2J2 MAOA MAOA ENSUAMP00000013975 ENSUAMP00000013975 ENSUAMP00000014003 ENSUAMP00000014003 ADH4 ADH4 ENSUAMP00000014774 ENSUAMP00000014774 ENSUAMP00000014798 ENSUAMP00000014798 ENSUAMP00000015522 ENSUAMP00000015522 POR POR ENSUAMP00000016286 ENSUAMP00000016286 TBXAS1 TBXAS1 CYP27B1 CYP27B1 AOC2 AOC2 AOC3 AOC3 EPHX1 EPHX1 CYP4F22 CYP4F22 ENSUAMP00000037275 ENSUAMP00000037275 ENSUAMP00000037273 ENSUAMP00000037273 CYP4F8 CYP4F8 ENSUAMP00000037267 ENSUAMP00000037267 ENSUAMP00000037252 ENSUAMP00000037252 MAOB MAOB NR1H4 NR1H4 SMOX SMOX CYP2U1 CYP2U1 ENSUAMP00000035567 ENSUAMP00000035567 CES5A CES5A TTI2 TTI2 NCOA2 NCOA2 CYP2W1 CYP2W1 ENSUAMP00000035193 ENSUAMP00000035193 ENSUAMP00000035192 ENSUAMP00000035192 CYP1A2 CYP1A2 CYP1A1 CYP1A1 ENSUAMP00000034639 ENSUAMP00000034639 ENSUAMP00000034638 ENSUAMP00000034638 CBFA2T2 CBFA2T2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FMO2Dimethylaniline monooxygenase [N-oxide-forming]. (535 aa)
ENSUAMP00000017348Uncharacterized protein; Belongs to the cytochrome P450 family. (339 aa)
CYP2F1Cytochrome P450 family 2 subfamily F member 1; Belongs to the cytochrome P450 family. (491 aa)
ENSUAMP00000017402Uncharacterized protein. (494 aa)
ENSUAMP00000018378Amino_oxidase domain-containing protein. (141 aa)
ENSUAMP00000018414Uncharacterized protein; Belongs to the cytochrome P450 family. (404 aa)
CYP39A1Cytochrome P450 family 39 subfamily A member 1; Belongs to the cytochrome P450 family. (469 aa)
ENSUAMP00000019082Uncharacterized protein; Belongs to the cytochrome P450 family. (411 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa)
ENSUAMP00000019124Uncharacterized protein. (241 aa)
CYP2R1Cytochrome P450 family 2 subfamily R member 1; Belongs to the cytochrome P450 family. (501 aa)
ENSUAMP00000019443Uncharacterized protein. (281 aa)
ENSUAMP00000019446Uncharacterized protein. (51 aa)
BPHLBiphenyl hydrolase like. (295 aa)
ENSUAMP00000020529Amino_oxidase domain-containing protein. (511 aa)
CYP24A1Cytochrome P450 family 24 subfamily A member 1; Belongs to the cytochrome P450 family. (516 aa)
ENSUAMP00000021070Uncharacterized protein. (833 aa)
HSP90AB1Heat shock protein 90 alpha family class B member 1. (728 aa)
FDX1Ferredoxin 1. (124 aa)
ENSUAMP00000021540Uncharacterized protein. (311 aa)
ENSUAMP00000022233Uncharacterized protein. (413 aa)
ENSUAMP00000022235Uncharacterized protein. (231 aa)
CYP8B1Cytochrome P450 family 8 subfamily B member 1; Belongs to the cytochrome P450 family. (501 aa)
ENSUAMP00000022865ACAS_N domain-containing protein. (125 aa)
CBR3Carbonyl reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (277 aa)
ENSUAMP00000023021Flavin-containing monooxygenase. (254 aa)
ENSUAMP00000023027Flavin-containing monooxygenase. (185 aa)
ENSUAMP00000023045Uncharacterized protein. (125 aa)
PTGS1Prostaglandin-endoperoxide synthase 1. (618 aa)
CYP20A1Cytochrome P450 family 20 subfamily A member 1. (470 aa)
AADACL4Arylacetamide deacetylase like 4. (404 aa)
AADACL3Arylacetamide deacetylase like 3. (350 aa)
ENSUAMP00000026182Abhydrolase_3 domain-containing protein. (237 aa)
ENSUAMP000000262942Fe-2S ferredoxin-type domain-containing protein. (253 aa)
PTGISProstaglandin I2 synthase; Belongs to the cytochrome P450 family. (499 aa)
RXRARetinoid X receptor alpha. (469 aa)
ENSUAMP00000027042ADH_N domain-containing protein. (95 aa)
ENSUAMP00000027762Uncharacterized protein. (188 aa)
CYP27A1Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family. (441 aa)
ENSUAMP00000028019Uncharacterized protein. (163 aa)
PTGES3Prostaglandin E synthase 3. (180 aa)
ENSUAMP00000028186Uncharacterized protein. (505 aa)
FMO5Dimethylaniline monooxygenase [N-oxide-forming]. (533 aa)
ENSUAMP00000028801BHLH domain-containing protein. (234 aa)
ENSUAMP00000028802Uncharacterized protein. (566 aa)
CYP21A2Cytochrome P450 family 21 subfamily A member 2; Belongs to the cytochrome P450 family. (493 aa)
FMO1Dimethylaniline monooxygenase [N-oxide-forming]. (532 aa)
FMO4Dimethylaniline monooxygenase [N-oxide-forming]. (556 aa)
CMBLCarboxymethylenebutenolidase homolog. (245 aa)
CCDC160Coiled-coil domain containing 160. (323 aa)
CYP11A1Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (482 aa)
ENSUAMP00000032152Uncharacterized protein. (503 aa)
ARNT2Aryl hydrocarbon receptor nuclear translocator 2. (706 aa)
AOC1Amine oxidase. (757 aa)
ENSUAMP00000033175Uncharacterized protein. (91 aa)
CYP51A1Cytochrome P450 family 51 subfamily A member 1; Belongs to the cytochrome P450 family. (503 aa)
CBFA2T3CBFA2/RUNX1 partner transcriptional co-repressor 3. (748 aa)
ENSUAMP00000033863Uncharacterized protein; Belongs to the cytochrome P450 family. (496 aa)
CYP2E1Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family. (494 aa)
MARC2Mitochondrial amidoxime reducing component 2. (311 aa)
ENSUAMP00000033988MOSC domain-containing protein. (270 aa)
CYP26B1Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa)
CYP4B1Cytochrome P450 family 4 subfamily B member 1; Belongs to the cytochrome P450 family. (493 aa)
CYP4X1Cytochrome P450 family 4 subfamily X member 1; Belongs to the cytochrome P450 family. (506 aa)
ENSUAMP00000034394Uncharacterized protein; Belongs to the cytochrome P450 family. (506 aa)
CYB5R3NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (301 aa)
ENSUAMP00000000355Uncharacterized protein. (58 aa)
ENSUAMP00000000729Uncharacterized protein; Belongs to the cytochrome P450 family. (180 aa)
ENSUAMP00000001000Aldedh domain-containing protein. (224 aa)
ENSUAMP00000001018Flavin-containing monooxygenase. (265 aa)
ENSUAMP00000001136Uncharacterized protein. (80 aa)
ENSUAMP00000001533Uncharacterized protein. (98 aa)
ENSUAMP00000001835Aldedh domain-containing protein. (222 aa)
CYP19A1Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family. (465 aa)
ENSUAMP00000002638Uncharacterized protein. (76 aa)
CYP26A1Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family. (497 aa)
CYP26C1Cytochrome P450 family 26 subfamily C member 1; Belongs to the cytochrome P450 family. (522 aa)
ENSUAMP00000003052Uncharacterized protein. (372 aa)
ADH6Alcohol dehydrogenase 6 (class V). (400 aa)
ENSUAMP00000003802Uncharacterized protein. (368 aa)
RUNX1T1RUNX1 partner transcriptional co-repressor 1. (603 aa)
ENSUAMP00000005042Uncharacterized protein. (463 aa)
ALDH1B1Aldehyde dehydrogenase 1 family member B1. (491 aa)
ENSUAMP00000006303Uncharacterized protein; Belongs to the cytochrome P450 family. (171 aa)
AIPPeptidylprolyl isomerase. (330 aa)
ENSUAMP00000006803Uncharacterized protein; Belongs to the cytochrome P450 family. (262 aa)
CYP7B1Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. (485 aa)
ENSUAMP00000007578ACAS_N domain-containing protein. (194 aa)
CES2Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (559 aa)
CES3Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (571 aa)
NCOA1Nuclear receptor coactivator. (1441 aa)
ENSUAMP00000009417Uncharacterized protein. (93 aa)
ALDH16A1Aldehyde dehydrogenase family 16 member A1. (819 aa)
FAM78AFamily with sequence similarity 78 member A. (283 aa)
NQO2N-ribosyldihydronicotinamide:quinone reductase 2. (231 aa)
ENSUAMP00000010632Uncharacterized protein; Belongs to the cytochrome P450 family. (494 aa)
ENSUAMP00000010766Uncharacterized protein. (93 aa)
ENSUAMP00000011012Aldedh domain-containing protein. (225 aa)
CYP27C1Cytochrome P450 family 27 subfamily C member 1; Belongs to the cytochrome P450 family. (372 aa)
POMCProopiomelanocortin. (223 aa)
ENSUAMP00000012176Uncharacterized protein. (507 aa)
ENSUAMP00000012528Uncharacterized protein; Belongs to the cytochrome P450 family. (500 aa)
CYP2B6Cytochrome P450 family 2 subfamily B member 6; Belongs to the cytochrome P450 family. (436 aa)
ARNTAryl hydrocarbon receptor nuclear translocator. (481 aa)
FDXRNADPH:adrenodoxin oxidoreductase, mitochondrial. (492 aa)
FADS6Fatty acid desaturase 6. (340 aa)
ENSUAMP00000013046Uncharacterized protein. (120 aa)
CYP46A1Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family. (506 aa)
ENSUAMP00000013261Uncharacterized protein. (134 aa)
CYP2J2Cytochrome P450 family 2 subfamily J member 2; Belongs to the cytochrome P450 family. (469 aa)
MAOAAmine oxidase. (417 aa)
ENSUAMP00000013975Uncharacterized protein; Belongs to the cytochrome P450 family. (181 aa)
ENSUAMP00000014003Aldedh domain-containing protein. (131 aa)
ADH4Alcohol dehydrogenase 4 (class II), pi polypeptide. (380 aa)
ENSUAMP00000014774Uncharacterized protein. (214 aa)
ENSUAMP00000014798S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (374 aa)
ENSUAMP00000015522Uncharacterized protein. (666 aa)
PORNADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (680 aa)
ENSUAMP00000016286Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (249 aa)
TBXAS1Thromboxane A synthase 1. (441 aa)
CYP27B1Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (508 aa)
AOC2Amine oxidase. (756 aa)
AOC3Amine oxidase. (763 aa)
EPHX1Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family. (444 aa)
CYP4F22Cytochrome P450 family 4 subfamily F member 22; Belongs to the cytochrome P450 family. (531 aa)
ENSUAMP00000037275Uncharacterized protein; Belongs to the cytochrome P450 family. (182 aa)
ENSUAMP00000037273Uncharacterized protein. (208 aa)
CYP4F8Uncharacterized protein; Belongs to the cytochrome P450 family. (524 aa)
ENSUAMP00000037267Uncharacterized protein. (83 aa)
ENSUAMP00000037252PKS_ER domain-containing protein. (390 aa)
MAOBAmine oxidase. (529 aa)
NR1H4Nuclear receptor subfamily 1 group H member 4. (482 aa)
SMOXSpermine oxidase. (549 aa)
CYP2U1Cytochrome P450 family 2 subfamily U member 1; Belongs to the cytochrome P450 family. (529 aa)
ENSUAMP00000035567Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (566 aa)
CES5ACarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (552 aa)
TTI2TELO2 interacting protein 2. (477 aa)
NCOA2Nuclear receptor coactivator 2. (945 aa)
CYP2W1Cytochrome P450 family 2 subfamily W member 1; Belongs to the cytochrome P450 family. (501 aa)
ENSUAMP00000035193Uncharacterized protein. (279 aa)
ENSUAMP00000035192Uncharacterized protein. (82 aa)
CYP1A2Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family. (512 aa)
CYP1A1Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. (516 aa)
ENSUAMP00000034639Uncharacterized protein. (463 aa)
ENSUAMP00000034638Uncharacterized protein; Belongs to the cytochrome P450 family. (490 aa)
CBFA2T2CBFA2/RUNX1 partner transcriptional co-repressor 2. (575 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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