STRINGSTRING
ENSUAMP00000029737 ENSUAMP00000029737 ENSUAMP00000028965 ENSUAMP00000028965 ENSUAMP00000028602 ENSUAMP00000028602 TUBB1 TUBB1 TUBB6 TUBB6 ENSUAMP00000027974 ENSUAMP00000027974 RANBP2 RANBP2 SKA1 SKA1 TUBB4B TUBB4B WAPL WAPL PPP2CB PPP2CB BIRC5 BIRC5 CENPT CENPT CENPQ CENPQ ENSUAMP00000026401 ENSUAMP00000026401 ENSUAMP00000026061 ENSUAMP00000026061 ENSUAMP00000025748 ENSUAMP00000025748 MAPRE2 MAPRE2 CENPL CENPL KIF2C KIF2C WDR41 WDR41 ENSUAMP00000024673 ENSUAMP00000024673 CDK1 CDK1 CENPU CENPU NUP107 NUP107 PPP2R5C PPP2R5C DYNC1H1 DYNC1H1 ENSUAMP00000023307 ENSUAMP00000023307 PPP2CA PPP2CA ENSUAMP00000023170 ENSUAMP00000023170 ZW10 ZW10 ENSUAMP00000022900 ENSUAMP00000022900 SEH1L SEH1L PPP2R5E PPP2R5E DYNC1I2 DYNC1I2 ENSUAMP00000022173 ENSUAMP00000022173 PPP2R5D PPP2R5D ENSUAMP00000021647 ENSUAMP00000021647 ENSUAMP00000021642 ENSUAMP00000021642 ENSUAMP00000020419 ENSUAMP00000020419 PPP2R5A PPP2R5A ERCC6L ERCC6L ENSUAMP00000019671 ENSUAMP00000019671 RCC2 RCC2 DYNLL1 DYNLL1 TUBB2A TUBB2A MAD2L1 MAD2L1 TUBE1 TUBE1 NDE1 NDE1 ENSUAMP00000018426 ENSUAMP00000018426 ENSUAMP00000018132 ENSUAMP00000018132 KIF18A KIF18A SGO2 SGO2 CDCA8 CDCA8 ENSUAMP00000017752 ENSUAMP00000017752 CENPP CENPP SKA2 SKA2 ZWINT ZWINT ENSUAMP00000017329 ENSUAMP00000017329 PAFAH1B1 PAFAH1B1 KIF2A KIF2A TUBB2B TUBB2B ENSUAMP00000015392 ENSUAMP00000015392 CDCA5 CDCA5 PPP2R5B PPP2R5B MIS12 MIS12 SPC24 SPC24 ENSUAMP00000014202 ENSUAMP00000014202 CENPC CENPC PPP1CC PPP1CC PPP2R1A PPP2R1A NUP85 NUP85 BUB1 BUB1 B9D2 B9D2 ENSUAMP00000012243 ENSUAMP00000012243 DYNLL2 DYNLL2 NDC80 NDC80 AURKC AURKC AHCTF1 AHCTF1 ENSUAMP00000011107 ENSUAMP00000011107 TUBA4A TUBA4A CLIP1 CLIP1 ENSUAMP00000009972 ENSUAMP00000009972 ENSUAMP00000009862 ENSUAMP00000009862 ENSUAMP00000009816 ENSUAMP00000009816 STAG1 STAG1 NUP37 NUP37 DSN1 DSN1 BUB3 BUB3 PDS5A PDS5A CENPO CENPO ENSUAMP00000008644 ENSUAMP00000008644 TUBAL3 TUBAL3 CENPF CENPF MAPRE3 MAPRE3 CENPA CENPA CCNB2 CCNB2 ENSUAMP00000007772 ENSUAMP00000007772 RAD21L1 RAD21L1 CENPM CENPM ENSUAMP00000007452 ENSUAMP00000007452 NUP43 NUP43 NUP160 NUP160 AURKB AURKB ENSUAMP00000005879 ENSUAMP00000005879 ENSUAMP00000005655 ENSUAMP00000005655 ENSUAMP00000005650 ENSUAMP00000005650 ENSUAMP00000005617 ENSUAMP00000005617 ENSUAMP00000005048 ENSUAMP00000005048 ENSUAMP00000004606 ENSUAMP00000004606 KIF2B KIF2B ENSUAMP00000003972 ENSUAMP00000003972 ENSUAMP00000003913 ENSUAMP00000003913 ENSUAMP00000003901 ENSUAMP00000003901 ENSUAMP00000003585 ENSUAMP00000003585 SPC25 SPC25 NSL1 NSL1 ENSUAMP00000003358 ENSUAMP00000003358 DYNC1LI2 DYNC1LI2 ENSUAMP00000002811 ENSUAMP00000002811 CCNB1 CCNB1 INCENP INCENP MEIOC MEIOC ENSUAMP00000001878 ENSUAMP00000001878 ENSUAMP00000001840 ENSUAMP00000001840 ENSUAMP00000001591 ENSUAMP00000001591 ENSUAMP00000000873 ENSUAMP00000000873 CDC20 CDC20 ENSUAMP00000000621 ENSUAMP00000000621 DYNC1I1 DYNC1I1 NDEL1 NDEL1 TUBB4A TUBB4A ZWILCH ZWILCH ENSUAMP00000030547 ENSUAMP00000030547 ENSUAMP00000030716 ENSUAMP00000030716 SMC1A SMC1A TMEM219 TMEM219 TAOK2 TAOK2 ENSUAMP00000031859 ENSUAMP00000031859 RANGAP1 RANGAP1 SEC13 SEC13 CLIP2 CLIP2 ENSUAMP00000032533 ENSUAMP00000032533 ENSUAMP00000032535 ENSUAMP00000032535 CKAP5 CKAP5 NUDC NUDC ENSUAMP00000034870 ENSUAMP00000034870 STAG2 STAG2 XPO1 XPO1 CENPI CENPI ENSUAMP00000035191 ENSUAMP00000035191 SMC3 SMC3 ENSUAMP00000035738 ENSUAMP00000035738 NUP98 NUP98 DYNC1LI1 DYNC1LI1 ENSUAMP00000036902 ENSUAMP00000036902 ENSUAMP00000037236 ENSUAMP00000037236 ENSUAMP00000037329 ENSUAMP00000037329
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSUAMP00000029737Uncharacterized protein. (105 aa)
ENSUAMP00000028965Uncharacterized protein. (199 aa)
ENSUAMP0000002860240S ribosomal protein S27. (90 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (457 aa)
TUBB6Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (432 aa)
ENSUAMP00000027974Uncharacterized protein. (70 aa)
RANBP2RAN binding protein 2. (2906 aa)
SKA1Spindle and kinetochore associated complex subunit 1. (255 aa)
TUBB4BTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
WAPLWAPL cohesin release factor. (1103 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
BIRC5Baculoviral IAP repeat containing 5. (142 aa)
CENPTCentromere protein T. (490 aa)
CENPQCentromere protein Q. (268 aa)
ENSUAMP0000002640140S ribosomal protein S27. (80 aa)
ENSUAMP00000026061Protein kinase domain-containing protein. (110 aa)
ENSUAMP00000025748Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (190 aa)
MAPRE2Microtubule associated protein RP/EB family member 2. (326 aa)
CENPLCentromere protein L. (346 aa)
KIF2CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (725 aa)
WDR41WD repeat domain 41. (459 aa)
ENSUAMP00000024673Uncharacterized protein. (102 aa)
CDK1Cyclin dependent kinase 1. (305 aa)
CENPUCentromere protein U. (384 aa)
NUP107Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (641 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (503 aa)
DYNC1H1Dynein cytoplasmic 1 heavy chain 1. (4647 aa)
ENSUAMP00000023307Uncharacterized protein. (243 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
ENSUAMP00000023170Uncharacterized protein. (348 aa)
ZW10Zw10 kinetochore protein. (739 aa)
ENSUAMP00000022900Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
SEH1LSEH1 like nucleoporin; Belongs to the WD repeat SEC13 family. (357 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (504 aa)
DYNC1I2Dynein cytoplasmic 1 intermediate chain 2. (650 aa)
ENSUAMP00000022173Uncharacterized protein. (86 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (601 aa)
ENSUAMP00000021647Rad21_Rec8_N domain-containing protein. (566 aa)
ENSUAMP00000021642Rad21_Rec8 domain-containing protein. (69 aa)
ENSUAMP00000020419Uncharacterized protein. (490 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (498 aa)
ERCC6LERCC excision repair 6 like, spindle assembly checkpoint helicase. (1117 aa)
ENSUAMP00000019671Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
RCC2Regulator of chromosome condensation 2. (508 aa)
DYNLL1Dynein light chain. (89 aa)
TUBB2ATubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (373 aa)
MAD2L1Mitotic arrest deficient 2 like 1. (205 aa)
TUBE1Tubulin epsilon 1; Belongs to the tubulin family. (475 aa)
NDE1NudE neurodevelopment protein 1. (346 aa)
ENSUAMP00000018426Tubulin_C domain-containing protein; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (250 aa)
ENSUAMP00000018132Uncharacterized protein. (68 aa)
KIF18AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (890 aa)
SGO2Shugoshin 2. (1094 aa)
CDCA8Cell division cycle associated 8. (281 aa)
ENSUAMP00000017752Uncharacterized protein. (755 aa)
CENPPCentromere protein P. (276 aa)
SKA2Spindle and kinetochore associated complex subunit 2. (117 aa)
ZWINTZW10 interacting kinetochore protein. (286 aa)
ENSUAMP00000017329Uncharacterized protein. (205 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)
KIF2AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (593 aa)
TUBB2BTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
ENSUAMP00000015392Uncharacterized protein. (1523 aa)
CDCA5Cell division cycle associated 5. (253 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (497 aa)
MIS12MIS12 kinetochore complex component. (212 aa)
SPC24SPC24 component of NDC80 kinetochore complex. (201 aa)
ENSUAMP00000014202Uncharacterized protein. (81 aa)
CENPCCentromere protein C. (929 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (326 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
NUP85Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (655 aa)
BUB1BUB1 mitotic checkpoint serine/threonine kinase. (1071 aa)
B9D2B9 domain containing 2. (175 aa)
ENSUAMP00000012243Dynein light chain. (89 aa)
DYNLL2Dynein light chain. (89 aa)
NDC80NDC80 kinetochore complex component. (642 aa)
AURKCAurora kinase C; Belongs to the protein kinase superfamily. (307 aa)
AHCTF1AT-hook containing transcription factor 1. (2138 aa)
ENSUAMP00000011107Uncharacterized protein; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (420 aa)
TUBA4ATubulin alpha 4a; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (708 aa)
CLIP1CAP-Gly domain containing linker protein 1. (1440 aa)
ENSUAMP00000009972Uncharacterized protein. (80 aa)
ENSUAMP00000009862Uncharacterized protein. (1645 aa)
ENSUAMP00000009816Uncharacterized protein. (49 aa)
STAG1Stromal antigen 1. (1002 aa)
NUP37Nucleoporin 37. (276 aa)
DSN1DSN1 component of MIS12 kinetochore complex. (356 aa)
BUB3BUB3 mitotic checkpoint protein. (326 aa)
PDS5AUncharacterized protein. (747 aa)
CENPOCentromere protein O. (285 aa)
ENSUAMP00000008644Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (477 aa)
TUBAL3Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (461 aa)
CENPFCentromere protein F. (3110 aa)
MAPRE3Microtubule associated protein RP/EB family member 3. (281 aa)
CENPACentromere protein A. (138 aa)
CCNB2Cyclin B2; Belongs to the cyclin family. (397 aa)
ENSUAMP00000007772Uncharacterized protein. (100 aa)
RAD21L1RAD21 cohesin complex component like 1. (554 aa)
CENPMCentromere protein M. (146 aa)
ENSUAMP0000000745240S ribosomal protein S27. (67 aa)
NUP43Nucleoporin 43. (380 aa)
NUP160Nucleoporin 160. (1435 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (344 aa)
ENSUAMP0000000587940S ribosomal protein S27. (128 aa)
ENSUAMP00000005655Tubulin domain-containing protein. (85 aa)
ENSUAMP00000005650Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (434 aa)
ENSUAMP00000005617Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (485 aa)
ENSUAMP00000005048Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (241 aa)
ENSUAMP00000004606Uncharacterized protein. (1041 aa)
KIF2BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (683 aa)
ENSUAMP00000003972Rod_C domain-containing protein. (136 aa)
ENSUAMP00000003913SNF2_N domain-containing protein. (268 aa)
ENSUAMP00000003901Uncharacterized protein. (1263 aa)
ENSUAMP00000003585Uncharacterized protein. (112 aa)
SPC25SPC25 component of NDC80 kinetochore complex. (226 aa)
NSL1NSL1 component of MIS12 kinetochore complex. (178 aa)
ENSUAMP00000003358SER_THR_PHOSPHATASE domain-containing protein. (106 aa)
DYNC1LI2Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (492 aa)
ENSUAMP00000002811Tubulin domain-containing protein. (97 aa)
CCNB1Cyclin B1; Belongs to the cyclin family. (425 aa)
INCENPInner centromere protein. (879 aa)
MEIOCMeiosis specific with coiled-coil domain. (960 aa)
ENSUAMP00000001878Dynein light chain. (174 aa)
ENSUAMP00000001840Uncharacterized protein. (586 aa)
ENSUAMP00000001591Uncharacterized protein. (65 aa)
ENSUAMP00000000873Uncharacterized protein. (805 aa)
CDC20Cell division cycle 20. (516 aa)
ENSUAMP00000000621Uncharacterized protein. (164 aa)
DYNC1I1Dynein cytoplasmic 1 intermediate chain 1. (590 aa)
NDEL1NudE neurodevelopment protein 1 like 1. (345 aa)
TUBB4ATubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
ZWILCHZwilch kinetochore protein. (584 aa)
ENSUAMP00000030547Uncharacterized protein. (268 aa)
ENSUAMP00000030716Uncharacterized protein. (98 aa)
SMC1AStructural maintenance of chromosomes protein. (1239 aa)
TMEM219Transmembrane protein 219. (240 aa)
TAOK2TAO kinase 2. (1049 aa)
ENSUAMP00000031859Uncharacterized protein. (107 aa)
RANGAP1Ran GTPase activating protein 1. (589 aa)
SEC13SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (311 aa)
CLIP2CAP-Gly domain containing linker protein 2. (1057 aa)
ENSUAMP00000032533Uncharacterized protein. (127 aa)
ENSUAMP00000032535Uncharacterized protein. (145 aa)
CKAP5Cytoskeleton associated protein 5. (1740 aa)
NUDCNuclear distribution C, dynein complex regulator. (308 aa)
ENSUAMP00000034870Uncharacterized protein. (48 aa)
STAG2Stromal antigen 2. (1189 aa)
XPO1Exportin 1. (1071 aa)
CENPICentromere protein I. (725 aa)
ENSUAMP00000035191SKA2 domain-containing protein. (57 aa)
SMC3Structural maintenance of chromosomes protein. (1215 aa)
ENSUAMP00000035738Uncharacterized protein. (1448 aa)
NUP98Nucleoporin 98. (1157 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (524 aa)
ENSUAMP00000036902Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (388 aa)
ENSUAMP00000037236Uncharacterized protein. (715 aa)
ENSUAMP00000037329Calponin-homology (CH) domain-containing protein. (205 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
Server load: low (38%) [HD]