STRINGSTRING
KAT6A KAT6A KANSL1L KANSL1L KAT8 KAT8 WDR5 WDR5 ING5 ING5 DMAP1 DMAP1 ATF2 ATF2 TADA2A TADA2A ENSUAMP00000009805 ENSUAMP00000009805 RBBP7 RBBP7 HAT1 HAT1 NCOA1 NCOA1 ENSUAMP00000007225 ENSUAMP00000007225 ENSUAMP00000006568 ENSUAMP00000006568 MORF4L2 MORF4L2 ENSUAMP00000023511 ENSUAMP00000023511 TEX30 TEX30 KAT7 KAT7 WDR5B WDR5B ELP6 ELP6 ENSUAMP00000029194 ENSUAMP00000029194 CREB5 CREB5 ZNF518A ZNF518A MORF4L1 MORF4L1 ENSUAMP00000027161 ENSUAMP00000027161 OGT OGT ENSUAMP00000029147 ENSUAMP00000029147 H2AC21 H2AC21 H2BC21 H2BC21 ENSUAMP00000029191 ENSUAMP00000029191 ENSUAMP00000029193 ENSUAMP00000029193 ENSUAMP00000014288 ENSUAMP00000014288 ENSUAMP00000014302 ENSUAMP00000014302 ENSUAMP00000015007 ENSUAMP00000015007 DR1 DR1 ENSUAMP00000015486 ENSUAMP00000015486 ENSUAMP00000015490 ENSUAMP00000015490 MRGBP MRGBP ENSUAMP00000016862 ENSUAMP00000016862 PHF20 PHF20 ENSUAMP00000006561 ENSUAMP00000006561 ENSUAMP00000006335 ENSUAMP00000006335 ENSUAMP00000006330 ENSUAMP00000006330 ENSUAMP00000006323 ENSUAMP00000006323 ENSUAMP00000006306 ENSUAMP00000006306 ENSUAMP00000006129 ENSUAMP00000006129 ENY2-2 ENY2-2 H2BC1 H2BC1 ENSUAMP00000004341 ENSUAMP00000004341 H2AJ H2AJ ENSUAMP00000003497 ENSUAMP00000003497 MEAF6 MEAF6 ENSUAMP00000018590 ENSUAMP00000018590 ENSUAMP00000018677 ENSUAMP00000018677 TAF5L TAF5L MSL2 MSL2 MSL1 MSL1 BRD1 BRD1 ENY2 ENY2 ENSUAMP00000014264 ENSUAMP00000014264 ENSUAMP00000014262 ENSUAMP00000014262 ENSUAMP00000014260 ENSUAMP00000014260 ENSUAMP00000014255 ENSUAMP00000014255 ENSUAMP00000014243 ENSUAMP00000014243 ENSUAMP00000014224 ENSUAMP00000014224 ENSUAMP00000014212 ENSUAMP00000014212 ENSUAMP00000014195 ENSUAMP00000014195 MCRS1 MCRS1 BRD8 BRD8 ENSUAMP00000002152 ENSUAMP00000002152 JADE1 JADE1 ENSUAMP00000001390 ENSUAMP00000001390 ENSUAMP00000001376 ENSUAMP00000001376 KANSL1 KANSL1 MSL3 MSL3 ENSUAMP00000029195 ENSUAMP00000029195 ENSUAMP00000000293 ENSUAMP00000000293 H2AC6 H2AC6 ENSUAMP00000020808 ENSUAMP00000020808 ENSUAMP00000020825 ENSUAMP00000020825 ENSUAMP00000020853 ENSUAMP00000020853 ELP3 ELP3 ENSUAMP00000017069 ENSUAMP00000017069 HIST3H2BB HIST3H2BB H2AW H2AW ENSUAMP00000021258 ENSUAMP00000021258 ELP2 ELP2 ENSUAMP00000022269 ENSUAMP00000022269 ENSUAMP00000022270 ENSUAMP00000022270 ENSUAMP00000022406 ENSUAMP00000022406 BRPF3 BRPF3 ENSUAMP00000033281 ENSUAMP00000033281 JADE3 JADE3 KAT14 KAT14 MBIP MBIP H2BC11 H2BC11 ENSUAMP00000033915 ENSUAMP00000033915 ENSUAMP00000033918 ENSUAMP00000033918 ENSUAMP00000033919 ENSUAMP00000033919 ENSUAMP00000033920 ENSUAMP00000033920 ENSUAMP00000033939 ENSUAMP00000033939 ENSUAMP00000033942 ENSUAMP00000033942 ENSUAMP00000033947 ENSUAMP00000033947 ENSUAMP00000033949 ENSUAMP00000033949 ENSUAMP00000033950 ENSUAMP00000033950 TAF6L TAF6L ENSUAMP00000034282 ENSUAMP00000034282 HCFC2 HCFC2 ENSUAMP00000034960 ENSUAMP00000034960 ELP1 ELP1 NCOA2 NCOA2 KANSL2 KANSL2 VPS72 VPS72 PAX3 PAX3 ENSUAMP00000029196 ENSUAMP00000029196 H2BC18 H2BC18 H2BE1 H2BE1 ING4 ING4 ATXN7L3 ATXN7L3 ENSUAMP00000031302 ENSUAMP00000031302 EP300 EP300 BRPF1 BRPF1 RUVBL2 RUVBL2 YEATS2 YEATS2 SGF29 SGF29 SAP130 SAP130 ENSUAMP00000011014 ENSUAMP00000011014
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KAT6AHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2004 aa)
KANSL1LKAT8 regulatory NSL complex subunit 1 like. (592 aa)
KAT8Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (458 aa)
WDR5WD repeat domain 5. (378 aa)
ING5Inhibitor of growth protein. (240 aa)
DMAP1DNA methyltransferase 1 associated protein 1. (468 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
TADA2ATranscriptional adapter. (443 aa)
ENSUAMP00000009805H15 domain-containing protein. (216 aa)
RBBP7RB binding protein 7, chromatin remodeling factor. (427 aa)
HAT1Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. (378 aa)
NCOA1Nuclear receptor coactivator. (1441 aa)
ENSUAMP00000007225Histone domain-containing protein; Belongs to the histone H2B family. (122 aa)
ENSUAMP00000006568annotation not available (130 aa)
MORF4L2Mortality factor 4 like 2. (288 aa)
ENSUAMP00000023511Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2075 aa)
TEX30Testis expressed 30. (225 aa)
KAT7Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (592 aa)
WDR5BWD repeat domain 5B. (330 aa)
ELP6Elongator acetyltransferase complex subunit 6. (266 aa)
ENSUAMP00000029194Histone H2A; Belongs to the histone H2A family. (130 aa)
CREB5cAMP responsive element binding protein 5. (327 aa)
ZNF518AZinc finger protein 518A. (1491 aa)
MORF4L1Mortality factor 4 like 1. (235 aa)
ENSUAMP00000027161Uncharacterized protein. (1009 aa)
OGTO-linked N-acetylglucosamine (GlcNAc) transferase. (978 aa)
ENSUAMP00000029147Histone H2A; Belongs to the histone H2A family. (128 aa)
H2AC21Histone H2A; Belongs to the histone H2A family. (130 aa)
H2BC21Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSUAMP00000029191Histone H2B; Belongs to the histone H2B family. (135 aa)
ENSUAMP00000029193annotation not available (126 aa)
ENSUAMP00000014288Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSUAMP00000014302Histone H2A; Belongs to the histone H2A family. (141 aa)
ENSUAMP00000015007ING domain-containing protein. (97 aa)
DR1Down-regulator of transcription 1. (176 aa)
ENSUAMP00000015486BTP domain-containing protein. (270 aa)
ENSUAMP00000015490Uncharacterized protein. (199 aa)
MRGBPMRG domain binding protein. (199 aa)
ENSUAMP00000016862Uncharacterized protein. (903 aa)
PHF20PHD finger protein 20. (1001 aa)
ENSUAMP00000006561Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSUAMP00000006335Histone H2B; Belongs to the histone H2B family. (135 aa)
ENSUAMP00000006330Histone H2A; Belongs to the histone H2A family. (130 aa)
ENSUAMP00000006323Histone H3; Belongs to the histone H3 family. (136 aa)
ENSUAMP00000006306annotation not available (103 aa)
ENSUAMP00000006129Histone domain-containing protein. (199 aa)
ENY2-2Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] (101 aa)
H2BC1Histone H2B; Belongs to the histone H2B family. (127 aa)
ENSUAMP00000004341annotation not available (103 aa)
H2AJHistone H2A; Belongs to the histone H2A family. (129 aa)
ENSUAMP00000003497Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
MEAF6MYST/Esa1 associated factor 6. (202 aa)
ENSUAMP00000018590Uncharacterized protein. (63 aa)
ENSUAMP00000018677Uncharacterized protein. (405 aa)
TAF5LTATA-box binding protein associated factor 5 like. (589 aa)
MSL2MSL complex subunit 2. (577 aa)
MSL1MSL complex subunit 1. (614 aa)
BRD1Bromodomain containing 1. (1129 aa)
ENY2Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] (163 aa)
ENSUAMP00000014264annotation not available (136 aa)
ENSUAMP00000014262Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (100 aa)
ENSUAMP00000014260annotation not available (103 aa)
ENSUAMP00000014255Histone H2A; Belongs to the histone H2A family. (130 aa)
ENSUAMP00000014243Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSUAMP00000014224annotation not available (103 aa)
ENSUAMP00000014212annotation not available (126 aa)
ENSUAMP00000014195annotation not available (130 aa)
MCRS1Microspherule protein 1. (534 aa)
BRD8Bromo domain-containing protein. (936 aa)
ENSUAMP00000002152Uncharacterized protein. (107 aa)
JADE1Jade family PHD finger 1. (843 aa)
ENSUAMP00000001390Uncharacterized protein. (232 aa)
ENSUAMP00000001376Uncharacterized protein. (256 aa)
KANSL1KAT8 regulatory NSL complex subunit 1. (662 aa)
MSL3MSL complex subunit 3. (448 aa)
ENSUAMP00000029195annotation not available (103 aa)
ENSUAMP00000000293Histone H2B; Belongs to the histone H2B family. (67 aa)
H2AC6Histone H2A; Belongs to the histone H2A family. (130 aa)
ENSUAMP00000020808annotation not available (126 aa)
ENSUAMP00000020825annotation not available (103 aa)
ENSUAMP00000020853Histone domain-containing protein. (178 aa)
ELP3Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. (524 aa)
ENSUAMP00000017069Histone H2B; Belongs to the histone H2B family. (126 aa)
HIST3H2BBHistone H2B; Belongs to the histone H2B family. (126 aa)
H2AWHistone H2A; Belongs to the histone H2A family. (130 aa)
ENSUAMP00000021258Uncharacterized protein. (129 aa)
ELP2Elongator acetyltransferase complex subunit 2. (737 aa)
ENSUAMP00000022269Histone H2A; Belongs to the histone H2A family. (132 aa)
ENSUAMP00000022270Histone H2B; Belongs to the histone H2B family. (127 aa)
ENSUAMP00000022406Uncharacterized protein. (242 aa)
BRPF3Bromodomain and PHD finger containing 3. (1206 aa)
ENSUAMP00000033281Uncharacterized protein. (173 aa)
JADE3Jade family PHD finger 3. (825 aa)
KAT14Lysine acetyltransferase 14. (780 aa)
MBIPMAP3K12 binding inhibitory protein 1. (343 aa)
H2BC11Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSUAMP00000033915Histone domain-containing protein. (125 aa)
ENSUAMP00000033918annotation not available (103 aa)
ENSUAMP00000033919Histone domain-containing protein; Belongs to the histone H2B family. (128 aa)
ENSUAMP00000033920annotation not available (128 aa)
ENSUAMP00000033939Histone H2B; Belongs to the histone H2B family. (132 aa)
ENSUAMP00000033942annotation not available (130 aa)
ENSUAMP00000033947Histone H2A; Belongs to the histone H2A family. (136 aa)
ENSUAMP00000033949annotation not available (126 aa)
ENSUAMP00000033950annotation not available (103 aa)
TAF6LTATA-box binding protein associated factor 6 like. (619 aa)
ENSUAMP00000034282Homeobox domain-containing protein. (301 aa)
HCFC2Host cell factor C2. (792 aa)
ENSUAMP00000034960C2H2-type domain-containing protein. (123 aa)
ELP1Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. (1311 aa)
NCOA2Nuclear receptor coactivator 2. (945 aa)
KANSL2KAT8 regulatory NSL complex subunit 2. (492 aa)
VPS72Vacuolar protein sorting 72 homolog. (364 aa)
PAX3Paired box 3. (489 aa)
ENSUAMP00000029196Histone H3; Belongs to the histone H3 family. (136 aa)
H2BC18Histone H2B; Belongs to the histone H2B family. (166 aa)
H2BE1Histone H2B; Belongs to the histone H2B family. (122 aa)
ING4Inhibitor of growth protein. (247 aa)
ATXN7L3Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] (408 aa)
ENSUAMP00000031302Histone domain-containing protein; Belongs to the histone H2B family. (170 aa)
EP300E1A binding protein p300. (2399 aa)
BRPF1Uncharacterized protein. (1253 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (525 aa)
YEATS2YEATS domain containing 2. (1327 aa)
SGF29SAGA complex associated factor 29. (334 aa)
SAP130Sin3A associated protein 130. (973 aa)
ENSUAMP00000011014Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (474 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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