50 items (Ursus americanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DLAT	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (647 aa)
	DHRS9	Dehydrogenase/reductase 9; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (319 aa)
	DHRS3	Dehydrogenase/reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa)
	PDK3	Protein-serine/threonine kinase. (382 aa)
	RXRA	Retinoid X receptor alpha. (469 aa)
	PDHX	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (501 aa)
	ENSUAMP00000027844	Nuc_recep-AF1 domain-containing protein. (202 aa)
	ENSUAMP00000027845	Uncharacterized protein. (347 aa)
	ENSUAMP00000028100	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (330 aa)
	ENSUAMP00000031210	Uncharacterized protein. (296 aa)
	PDK1	Protein-serine/threonine kinase. (438 aa)
	PDHA1	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (390 aa)
	RDH14	Retinol dehydrogenase 14; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (336 aa)
	CPT1A	Carnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (773 aa)
	SDR16C5	Short chain dehydrogenase/reductase family 16C member 5; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (309 aa)
	PDK2	Protein-serine/threonine kinase. (249 aa)
	PDHB	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (359 aa)
	ENSUAMP00000037358	Uncharacterized protein. (119 aa)
	ALDH1A3	Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family. (512 aa)
	PDHA2	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (391 aa)
	ADH4	Alcohol dehydrogenase 4 (class II), pi polypeptide. (380 aa)
	RDH16	Retinol dehydrogenase 16; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (317 aa)
	ENSUAMP00000013328	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (237 aa)
	DLD	Dihydrolipoyl dehydrogenase. (509 aa)
	RARB	Retinoic acid receptor beta. (336 aa)
	ENSUAMP00000012221	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (317 aa)
	ENSUAMP00000012166	FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa)
	RDH10	Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
	DHRS2	Dehydrogenase/reductase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (245 aa)
	CPT1C	Carnitine palmitoyltransferase 1C; Belongs to the carnitine/choline acetyltransferase family. (803 aa)
	RARA	Retinoic acid receptor alpha. (462 aa)
	AKR1C8P	Aldo-keto reductase family 1 member C8, pseudogene. (324 aa)
	PDK4	Protein-serine/threonine kinase. (412 aa)
	ENSUAMP00000006381	Uncharacterized protein. (307 aa)
	ENSUAMP00000005111	Aldedh domain-containing protein. (208 aa)
	ENSUAMP00000003802	Uncharacterized protein. (368 aa)
	RARG	Retinoic acid receptor gamma. (458 aa)
	ENSUAMP00000003052	Uncharacterized protein. (372 aa)
	ENSUAMP00000016286	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (249 aa)
	CRABP2	Cellular retinoic acid binding protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (185 aa)
	PPARD	Peroxisome proliferator activated receptor delta. (441 aa)
	RDH5	Retinol dehydrogenase 5; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (318 aa)
	CYP26C1	Cytochrome P450 family 26 subfamily C member 1; Belongs to the cytochrome P450 family. (522 aa)
	CPT1B	Carnitine palmitoyltransferase 1B; Belongs to the carnitine/choline acetyltransferase family. (772 aa)
	ALDH8A1	Aldehyde dehydrogenase 8 family member A1; Belongs to the aldehyde dehydrogenase family. (487 aa)
	ENSUAMP00000001000	Aldedh domain-containing protein. (224 aa)
	DHRS13	Dehydrogenase/reductase 13. (374 aa)
	ENSUAMP00000021877	Uncharacterized protein. (80 aa)
	RDH13	Retinol dehydrogenase 13; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (334 aa)
	CRABP1	Cellular retinoic acid binding protein 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (137 aa)

Your Current Organism:

Ursus americanus

NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADH4	ALDH1A3	ENSUAMP00000014759	ENSUAMP00000037474	Alcohol dehydrogenase 4 (class II), pi polypeptide.	Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family.	0.952
ADH4	ALDH8A1	ENSUAMP00000014759	ENSUAMP00000001146	Alcohol dehydrogenase 4 (class II), pi polypeptide.	Aldehyde dehydrogenase 8 family member A1; Belongs to the aldehyde dehydrogenase family.	0.583
ADH4	DHRS3	ENSUAMP00000014759	ENSUAMP00000024908	Alcohol dehydrogenase 4 (class II), pi polypeptide.	Dehydrogenase/reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.478
ADH4	ENSUAMP00000001000	ENSUAMP00000014759	ENSUAMP00000001000	Alcohol dehydrogenase 4 (class II), pi polypeptide.	Aldedh domain-containing protein.	0.920
ADH4	ENSUAMP00000003052	ENSUAMP00000014759	ENSUAMP00000003052	Alcohol dehydrogenase 4 (class II), pi polypeptide.	Uncharacterized protein.	0.873
ADH4	ENSUAMP00000003802	ENSUAMP00000014759	ENSUAMP00000003802	Alcohol dehydrogenase 4 (class II), pi polypeptide.	Uncharacterized protein.	0.873
ADH4	ENSUAMP00000005111	ENSUAMP00000014759	ENSUAMP00000005111	Alcohol dehydrogenase 4 (class II), pi polypeptide.	Aldedh domain-containing protein.	0.890
ADH4	ENSUAMP00000013328	ENSUAMP00000014759	ENSUAMP00000013328	Alcohol dehydrogenase 4 (class II), pi polypeptide.	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	0.890
ADH4	ENSUAMP00000016286	ENSUAMP00000014759	ENSUAMP00000016286	Alcohol dehydrogenase 4 (class II), pi polypeptide.	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	0.920
AKR1C8P	RDH16	ENSUAMP00000008587	ENSUAMP00000013503	Aldo-keto reductase family 1 member C8, pseudogene.	Retinol dehydrogenase 16; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.819
ALDH1A3	ADH4	ENSUAMP00000037474	ENSUAMP00000014759	Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family.	Alcohol dehydrogenase 4 (class II), pi polypeptide.	0.952
ALDH1A3	CYP26C1	ENSUAMP00000037474	ENSUAMP00000002970	Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family.	Cytochrome P450 family 26 subfamily C member 1; Belongs to the cytochrome P450 family.	0.958
ALDH1A3	DHRS2	ENSUAMP00000037474	ENSUAMP00000008969	Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family.	Dehydrogenase/reductase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.853
ALDH1A3	DHRS3	ENSUAMP00000037474	ENSUAMP00000024908	Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family.	Dehydrogenase/reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.971
ALDH1A3	DHRS9	ENSUAMP00000037474	ENSUAMP00000024710	Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family.	Dehydrogenase/reductase 9; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.955
ALDH1A3	ENSUAMP00000001000	ENSUAMP00000037474	ENSUAMP00000001000	Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family.	Aldedh domain-containing protein.	0.872
ALDH1A3	ENSUAMP00000003052	ENSUAMP00000037474	ENSUAMP00000003052	Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family.	Uncharacterized protein.	0.890
ALDH1A3	ENSUAMP00000003802	ENSUAMP00000037474	ENSUAMP00000003802	Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family.	Uncharacterized protein.	0.890
ALDH1A3	ENSUAMP00000005111	ENSUAMP00000037474	ENSUAMP00000005111	Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family.	Aldedh domain-containing protein.	0.873
ALDH1A3	ENSUAMP00000006381	ENSUAMP00000037474	ENSUAMP00000006381	Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family.	Uncharacterized protein.	0.887